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Transcript: Ezra Klein Interviews Patrick Collison - The New York Times
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font-size: 14px;
color: rgba(0,0,0,1);
}
.light-13aB1LNX .error-17l_qAZg{
color: rgba(255,255,255,1);
}
.error__message-3PJMFdo7 {
display: flex;
flex-direction: column;
justify-content: center;
}
.error__message-3PJMFdo7 span {
line-height: normal;
}
.transcript-AcUHctkp svg path,
.retry-1jk1WyCq svg,
.fatal-2c7Uwq9U svg {
fill: rgba(0,0,0,1);
transition: fill 0.25s, transform 300ms ease-out;
}
.light-13aB1LNX .transcript-AcUHctkp svg path,
.light-13aB1LNX .retry-1jk1WyCq svg,
.light-13aB1LNX .fatal-2c7Uwq9U svg {
fill: #ffffff;
}
.retry-1jk1WyCq {
width: 30px;
height: 30px;
flex-shrink: 0;
}
.fatal-2c7Uwq9U {
display: flex;
justify-content: center;
align-items: center;
width: 30px;
height: 30px;
}
.container__playback-MRa1r7AF{
display: flex;
justify-content: center;
align-items: center;
width: 100%;
flex: 1 0 auto;
padding-bottom: 20px;
}
.container__duration-3gYKdJ0v {
position: absolute;
top: 50%;
margin-top: 10px;
}
.container__transcript-V0fC4Xbd{
position: absolute;
top: 50%;
margin-top: 40px;
}
.container__timeline-_2TEK9Uc{
display: flex;
align-items: center;
flex-shrink: 0;
width: 100%;
height: 40px;
}
]]>
</style>
<style>
<![CDATA[
.fast-forward-1JbaMpeL svg {
fill: rgba(0,0,0,1);
transition: fill 0.25s, transform 300ms;
}
.desktop-Q_FP0IBX.fast-forward-1JbaMpeL:hover svg,
.desktop-Q_FP0IBX.fast-forward-1JbaMpeL:focus svg {
fill: rgba(0,0,0,.8);
}
.light-1gwOs_oX.fast-forward-1JbaMpeL svg {
fill: #ffffff;
}
.desktop-Q_FP0IBX.light-1gwOs_oX.fast-forward-1JbaMpeL:hover svg,
.desktop-Q_FP0IBX.light-1gwOs_oX.fast-forward-1JbaMpeL:focus svg{
fill: rgba(255, 255, 255, 0.8);
}
/* on safari the svg is cropped,
* so increase the container's size as a hacky fix */
.fast-forward-1JbaMpeL {
width: 31px;
height: 31px;
}
.fast-forward-1JbaMpeL svg {
width: 30px;
height: 30px;
}
/* disable these buttons */
.fast-forward-1JbaMpeL:disabled svg {
fill: rgba(68, 68, 68, 0.2);
}
.light-1gwOs_oX.fast-forward-1JbaMpeL:disabled svg {
fill: rgba(255, 255, 255, 0.2);
}
/* temp fix, without .desktop these disabled rules will not apply on desktop */
.desktop-Q_FP0IBX.fast-forward-1JbaMpeL:disabled svg {
fill: rgba(68, 68, 68, 0.2);
}
.desktop-Q_FP0IBX.light-1gwOs_oX.fast-forward-1JbaMpeL:disabled svg {
fill: rgba(255, 255, 255, 0.2);
}
]]>
</style>
<style>
<![CDATA[
.spinner-1Hq-hFPQ {
position: absolute;
top: 0;
right: 0;
bottom: 0;
left: 0;
z-index: 1;
opacity: 0;
transition: opacity 300ms ease-out;
box-sizing: border-box;
display: block;
}
.light-3nw-C-jF.spinner-1Hq-hFPQ {
border-color: #ffffff;
}
@-webkit-keyframes spin-2z3vTCsk {
0% {
transform: rotate(0deg);
}
100% {
transform: rotate(360deg);
}
}
@keyframes spin-2z3vTCsk {
0% {
transform: rotate(0deg);
}
100% {
transform: rotate(360deg);
}
}
.spinner-1Hq-hFPQ span {
display: block;
box-sizing: border-box;
position: absolute;
top: 0;
right: 0;
bottom: 0;
left: 0;
clip: rect(20px, 40px, 40px, 0);
opacity: 0;
-webkit-animation: none;
animation: none;
}
.vhs-xxs-3hr2ui_L.spinner-1Hq-hFPQ span{
clip: rect(15px, 30px, 30px, 0);
}
.vhs-l-1ZqhWwUO.spinner-1Hq-hFPQ span,
.vhs-xl-3MIWo5E4.spinner-1Hq-hFPQ span,
.vhs-xxl-U4fBIHnp.spinner-1Hq-hFPQ span {
clip: rect(25px, 60px, 60px, 0);
}
.mobile-2uGwuiaY.spinner-1Hq-hFPQ span {
clip: rect(25px, 60px, 60px, 0);
}
.spinner-1Hq-hFPQ span::after {
content: '';
box-sizing: border-box;
position: absolute;
top: 0;
right: 0;
bottom: 0;
left: 0;
border: 2px solid rgba(0,0,0,1);
border-radius: 50%;
}
.light-3nw-C-jF.spinner-1Hq-hFPQ span::after {
border-color: #ffffff;
}
.show-ucO_HEmS.spinner-1Hq-hFPQ {
opacity: 1;
transition: opacity 300ms ease-out 300ms;
-webkit-animation: spin-2z3vTCsk 3000ms linear infinite;
animation: spin-2z3vTCsk 3000ms linear infinite;
}
.show-ucO_HEmS.spinner-1Hq-hFPQ span {
opacity: 1;
transition: opacity 300ms ease-out;
-webkit-animation: spin-2z3vTCsk 1500ms cubic-bezier(0.77, 0, 0.175, 1) infinite;
animation: spin-2z3vTCsk 1500ms cubic-bezier(0.77, 0, 0.175, 1) infinite;
}
]]>
</style>
<style>
<![CDATA[
.circle-3tIPiHv_ {
position: absolute;
top: 0;
right: 0;
bottom: 0;
left: 0;
background: rgba(0, 0, 0, 0.1) !important;
border: 2px solid rgba(0,0,0,1);
border-radius: 50%;
opacity: 0;
transition: opacity 300ms;
}
.light-r2C9sdad .circle-3tIPiHv_{
border-color: #ffffff;
}
.circle-3tIPiHv_.show-2_w5iJaH {
opacity: 1;
}
.play-28dQRyDj svg,
.pause-37Q2gZNG svg {
fill: rgba(0,0,0,1);
transition: fill 300ms, transform 300ms 150ms, opacity 300ms;
}
.desktop-33nblbsH.play-28dQRyDj.hover-10Dv3gd- svg,
.desktop-33nblbsH.play-28dQRyDj:focus svg,
.desktop-33nblbsH.pause-37Q2gZNG:hover svg,
.desktop-33nblbsH.pause-37Q2gZNG:focus svg {
fill: rgba(0,0,0,.8);
transition: transform 300ms;
}
.light-r2C9sdad.play-28dQRyDj svg,
.light-r2C9sdad.pause-37Q2gZNG svg {
fill: #ffffff;
}
.desktop-33nblbsH.light-r2C9sdad.play-28dQRyDj.hover-10Dv3gd- svg,
.desktop-33nblbsH.light-r2C9sdad.play-28dQRyDj:focus svg,
.desktop-33nblbsH.light-r2C9sdad.pause-37Q2gZNG:hover svg,
.desktop-33nblbsH.light-r2C9sdad.pause-37Q2gZNG:focus svg{
fill: rgba(255, 255, 255, 0.8);
}
.play-28dQRyDj,
.pause-37Q2gZNG {
width: 40px;
height: 40px;
position: relative;
}
.vhs-xxs-rHlekkTR.play-28dQRyDj,
.vhs-xxs-rHlekkTR.pause-37Q2gZNG {
width: 30px;
height: 30px;
}
.vhs-xxl-3lVk_QqP.play-28dQRyDj,
.vhs-xxl-3lVk_QqP.pause-37Q2gZNG,
.vhs-xl-2OarcCIE.play-28dQRyDj,
.vhs-xl-2OarcCIE.pause-37Q2gZNG,
.vhs-l-2D9eQpBq.play-28dQRyDj,
.vhs-l-2D9eQpBq.pause-37Q2gZNG {
width: 50px;
height: 50px;
}
.mobile-1Jw2b02E.play-28dQRyDj,
.mobile-1Jw2b02E.pause-37Q2gZNG {
width: 60px;
height: 60px;
margin: 0 25px;
flex-shrink: 0;
margin-bottom: 12px !important;
}
.mobile-1Jw2b02E .play-triangle-3-_pUfBt {
transform: scale(0.5) translateX(8px);
fill: rgba(0,0,0,1);
}
.desktop-33nblbsH.cover-3XHYXLXi.play-28dQRyDj.hover-10Dv3gd- .play-triangle-3-_pUfBt {
transform: scale(0.5) translateX(5px);
fill: rgba(0,0,0,1);
}
.vhs-xxs-rHlekkTR.cover-3XHYXLXi.play-28dQRyDj.hover-10Dv3gd- .play-triangle-3-_pUfBt {
transform: scale(0.5) translateX(4px);
}
.vhs-l-2D9eQpBq.cover-3XHYXLXi.play-28dQRyDj.hover-10Dv3gd- .play-triangle-3-_pUfBt,
.vhs-xl-2OarcCIE.cover-3XHYXLXi.play-28dQRyDj.hover-10Dv3gd- .play-triangle-3-_pUfBt,
.vhs-xxl-3lVk_QqP.cover-3XHYXLXi.play-28dQRyDj.hover-10Dv3gd- .play-triangle-3-_pUfBt {
transform: scale(0.5) translateX(6px);
}
.mobile-1Jw2b02E .pause-bars-rOm1UnhP {
transform: scale(0.5);
fill: rgba(0,0,0,1);
}
.light-r2C9sdad.mobile-1Jw2b02E .play-triangle-3-_pUfBt,
.light-r2C9sdad.cover-3XHYXLXi.play-28dQRyDj.hover-10Dv3gd- .play-triangle-3-_pUfBt,
.light-r2C9sdad.mobile-1Jw2b02E .pause-bars-rOm1UnhP {
fill: #ffffff;
}
.play-triangle-3-_pUfBt,
.pause-bars-rOm1UnhP {
z-index: 2;
opacity: 1;
transform: scale(1) translateX(0);
}
.buffering-2_Sqh_Nu .play-triangle-3-_pUfBt {
opacity: 0.5;
transform: scale(0.5) translateX(5px);
transform-origin: center;
transition: transform 300ms, opacity 300ms;
}
.vhs-xxs-rHlekkTR.buffering-2_Sqh_Nu .play-triangle-3-_pUfBt {
transform: scale(0.5) translateX(4px);
}
.vhs-l-2D9eQpBq.buffering-2_Sqh_Nu .play-triangle-3-_pUfBt,
.vhs-xl-2OarcCIE.buffering-2_Sqh_Nu .play-triangle-3-_pUfBt,
.vhs-xxl-3lVk_QqP.buffering-2_Sqh_Nu .play-triangle-3-_pUfBt {
transform: scale(0.5) translateX(6px);
}
.mobile-1Jw2b02E.buffering-2_Sqh_Nu .play-triangle-3-_pUfBt {
transform: scale(0.5) translateX(8px);
}
.buffering-2_Sqh_Nu .pause-bars-rOm1UnhP {
opacity: 0.5;
transform: scale(0.5);
transition: transform 300ms, opacity 300ms;
}
]]>
</style>
<style>
<![CDATA[
.rewind-3JjXn1Ko svg {
fill: rgba(0,0,0,1);
transition: fill 0.25s, transform 300ms;
}
.desktop-o0RixJeK.rewind-3JjXn1Ko:hover svg,
.desktop-o0RixJeK.rewind-3JjXn1Ko:focus svg {
fill: rgba(0,0,0,.8);
}
.light-Lxh25U-X.rewind-3JjXn1Ko svg {
fill: #ffffff;
}
.desktop-o0RixJeK.light-Lxh25U-X.rewind-3JjXn1Ko:hover svg,
.desktop-o0RixJeK.light-Lxh25U-X.rewind-3JjXn1Ko:focus svg {
fill: rgba(255, 255, 255, 0.8);
}
/* on safari the svg is cropped,
* so increase the container's size as a hacky fix */
.rewind-3JjXn1Ko {
width: 31px;
height: 31px;
}
.rewind-3JjXn1Ko svg{
width: 30px;
height: 30px;
}
/* disable these buttons */
.rewind-3JjXn1Ko:disabled svg {
fill: rgba(68, 68, 68, 0.2);
}
.light-Lxh25U-X.rewind-3JjXn1Ko:disabled svg {
fill: rgba(255, 255, 255, 0.2);
}
/* temp fix, without .desktop these disabled rules will not apply on desktop */
.desktop-o0RixJeK.rewind-3JjXn1Ko:disabled svg {
fill: rgba(68, 68, 68, 0.2);
}
.desktop-o0RixJeK.light-Lxh25U-X.rewind-3JjXn1Ko:disabled svg {
fill: rgba(255, 255, 255, 0.2);
}
]]>
</style>
<style>
<![CDATA[
.handle-yWumRNVF {
position: absolute;
top: 50%;
left: 50%;
transform: translate(-50%, -50%);
z-index: 5;
fill:#000000;
}
.light-1iQ_-Gik .handle-yWumRNVF {
fill: #f7f7f7;
}
.desktop-1y6HQ4wj .handle-yWumRNVF {
width: 12px;
height: 12px;
}
.desktop-1y6HQ4wj.scrubbing-1jGsslgJ .handle-yWumRNVF {
width: 6px;
height: 6px;
}
.scrubbing-1jGsslgJ .handle-yWumRNVF {
width: 12px;
height: 12px;
}
.ink-2JygG5tZ {
transform: scale(0);
width: 40px;
height: 40px;
}
.scrubbing-1jGsslgJ .ink-2JygG5tZ {
transform: scale(1) ;
-webkit-animation: ripple-3czL9qGK 200ms ease;
animation: ripple-3czL9qGK 200ms ease;
z-index: 4;
fill: rgba(0, 0, 0, 0.2);
}
.light-1iQ_-Gik.scrubbing-1jGsslgJ .ink-2JygG5tZ {
fill: rgba(255, 255, 255, 0.2);
}
@-webkit-keyframes ripple-3czL9qGK {
from {
transform: scale(0);
}
to {
transform: scale(1);
}
}
@keyframes ripple-3czL9qGK {
from {
transform: scale(0);
}
to {
transform: scale(1);
}
}
]]>
</style>
<style>
<![CDATA[
.scrubberContainer-1WyrbTR8 {
position: absolute;
left: 0;
z-index: 4;
height: 100%;
opacity: 1;
transform: scale(1);
transform-origin: center left;
transition: opacity 150ms ease-out, transform 150ms ease-out;
}
.scrubberContainer-1WyrbTR8.scrubberContainerHide-38e1Psy2{
opacity: 0;
transform: scale(0.1);
transition: opacity 150ms ease-in, transform 150ms ease-in;
}
.center-2ePOhelf {
display: flex;
justify-content: center;
align-items: center;
height: 100%;
width: 100%;
}
.timeline-3hWvXF_F {
flex-grow: 1;
cursor: pointer;
position: relative;
height: 40px;
transition: transform 400ms ease-out;
transform-origin: right;
transform: scaleX(1);
}
.timeline-3hWvXF_F.timeline--placeholder-3vi2HDMp {
cursor: inherit;
}
.timeline__progress-1G5PcPam {
width: 0%;
height: 2px;
margin: 19px 0;
position: absolute;
background: rgba(0, 0, 0, 1);
z-index: 3;
}
.light-Hbch6i4G .timeline__progress-1G5PcPam {
background: rgba(255, 255, 255);
}
.timeline__buffered-3wXSHzxd {
width: 0%;
height: 2px;
margin: 19px 0;
position: absolute;
background: rgba(0, 0, 0, .2);
z-index: 2;
}
.light-Hbch6i4G .timeline__buffered-3wXSHzxd {
background: rgba(255, 255, 255, 0.4);
}
.timeline__duration-2wArYQHv {
width: 100%;
height: 2px;
margin: 19px 0;
position: absolute;
background: rgba(0, 0, 0, .1);
z-index: 1;
}
.light-Hbch6i4G .timeline__duration-2wArYQHv {
background: rgba(255, 255, 255, 0.2);
}
.animate-25gH6GDN {
transition: all 800ms ease !important;
}
/*
* This is just used for keyboard control of the "slider"
* We have to use the ARIA slider role instead of an input
* It's just an extra <div> with some keyboard handlers and an outline
*/
.timeline__slider-3bratC31:focus {
height: 2px;
width: 100%;
outline: 1px solid #4a90e2;
outline-offset: 1px;
}
]]>
</style>
<style>
<![CDATA[
.volume-1O8d0eUA {
width: 24px;
height: 24px;
flex-shrink: 0;
}
.volume-1O8d0eUA svg {
fill: rgba(0,0,0,1);
transition: fill 0.25s, transform 300ms;
}
.desktop-3zq1efKR.volume-1O8d0eUA:hover svg,
.desktop-3zq1efKR.volume-1O8d0eUA:focus svg {
fill: rgba(0,0,0,.8);
}
.light-npGsxX0d.volume-1O8d0eUA svg {
fill: #ffffff;
}
.desktop-3zq1efKR.light-npGsxX0d.volume-1O8d0eUA:hover svg,
.desktop-3zq1efKR.light-npGsxX0d.volume-1O8d0eUA:focus svg {
fill: rgba(255, 255, 255, 0.8);
}
.volume-1O8d0eUA:disabled svg {
fill: rgba(68, 68, 68, 0.2);
}
.light-npGsxX0d.volume-1O8d0eUA:disabled svg {
fill: rgba(255, 255, 255, 0.2);
}
/* temp fix, without .desktop these disabled rules will not apply on desktop */
.desktop-3zq1efKR.volume-1O8d0eUA:disabled svg {
fill: rgba(68, 68, 68, 0.2);
}
.desktop-3zq1efKR.light-npGsxX0d.volume-1O8d0eUA:disabled svg {
fill: rgba(255, 255, 255, 0.2);
}
]]>
</style>
<style>
<![CDATA[
.center-1rJo-uv- {
display: flex;
justify-content: center;
align-items: center;
height: 100%;
width: 100%;
}
]]>
</style>
<style>
<![CDATA[
.tbutton-2L0GaJtC {
margin-top: 5px !important;
background: transparent;
height: 45px;
width: 140px;
color: white;
border: 1px solid !important;
border-radius: 4px;
box-sizing: border-box;
display: flex;
flex-direction: column;
justify-content: center;
align-self: center;
align-items: center;
transition: 0.3s ease;
}
.tbuttonLightTheme-3bup-CvX.tbutton-2L0GaJtC {
border-color: transparent !important;
background: rgba(0, 0, 0, 0.1) !important;
}
.tbuttonDarkTheme-cv8xEMJI.tbutton-2L0GaJtC {
border-color: #000000 !important;
}
.tbutton-2L0GaJtC:hover {
border: 1px rgba(255, 255, 255, 1) solid;
background: rgba(0, 0, 0, 0.1);
}
.tbutton-2L0GaJtC:focus {
border: 1px rgba(255, 255, 255, 1) solid;
background: rgba(0, 0, 0, 0.25);
}
.textSpan-2JDJ9ilH {
font-weight: bold;
font-size: 14px;
line-height: 20px;
margin-left: 15px;
}
.tbuttonLightTheme-3bup-CvX .textSpan-2JDJ9ilH {
color: #ffffff;
}
.tbuttonDarkTheme-cv8xEMJI .textSpan-2JDJ9ilH {
color: #000000;
}
.buttonContentContainer-1HitmpQG {
display: flex;
flex-direction: row;
margin: auto 15px;
}
]]>
</style>
<style>
<![CDATA[
.wrapper-1psnlQub {
position: relative;
height: 70px;
}
.fadeable-card-7GXsqINn {
position: absolute;
top: 0;
right: 0;
bottom: 0;
left: 0;
opacity: 0;
transition: opacity 300ms ease-in;
pointer-events: none;
}
.fadeable-card--show-3JkJnOAd {
pointer-events: auto;
opacity: 1;
transition: opacity 300ms ease-out 600ms;
}
.container-PA2EXLwh {
display: flex;
align-items: center;
height: 40px;
line-height: 40px;
padding: 15px 20px;
}
.chunk-140HiJJE + .chunk-140HiJJE {
margin-left: 20px;
}
.small-zlxYcudU .chunk-140HiJJE + .chunk-140HiJJE {
margin-left: 10px;
}
.wrapper-1psnlQub button {
border: none;
margin: 0;
padding: 0;
background: none;
cursor: pointer;
-webkit-tap-highlight-color: transparent;
}
/* https://stackoverflow.com/a/30871205/3437335 */
.wrapper-1psnlQub use {
pointer-events: none;
}
.play-3nZmdAx2 svg,
.pause-ohgGg9mU svg,
.rewind-3plmLEaJ svg,
.fast-forward-1eC-z6CY svg,
.volume-2gdcbXfJ svg,
.retry-2FkTPmFi svg,
.fatal-2lTbqkU4 svg {
fill: #666666;
}
.play-3nZmdAx2:hover svg,
.play-3nZmdAx2:focus svg,
.pause-ohgGg9mU:hover svg,
.pause-ohgGg9mU:focus svg,
.rewind-3plmLEaJ:hover svg,
.rewind-3plmLEaJ:focus svg,
.fast-forward-1eC-z6CY:hover svg,
.fast-forward-1eC-z6CY:focus svg,
.volume-2gdcbXfJ:hover svg,
.volume-2gdcbXfJ:focus svg {
fill: #999999;
}
.play-3nZmdAx2.active-NDVLZmwo:hover svg,
.play-3nZmdAx2.active-NDVLZmwo:focus svg,
.pause-ohgGg9mU.active-NDVLZmwo:hover svg,
.pause-ohgGg9mU.active-NDVLZmwo:focus svg,
.retry-2FkTPmFi:hover svg,
.retry-2FkTPmFi:focus svg {
fill: #6288a5;
}
.volume-2gdcbXfJ svg .volume__stroke-3KYHtFZw {
stroke: #666666;
}
.volume-2gdcbXfJ:hover svg .volume__stroke-3KYHtFZw,
.volume-2gdcbXfJ:focus svg .volume__stroke-3KYHtFZw {
stroke: #999999;
}
.play-3nZmdAx2,
.pause-ohgGg9mU {
width: 40px;
height: 40px;
cursor: pointer;
position: relative;
transform: scale(1);
}
.small-zlxYcudU .play-3nZmdAx2,
.small-zlxYcudU .pause-ohgGg9mU {
transform: scale(0.75);
transform-origin: center right;
margin-left: -10px;
}
.rewind-3plmLEaJ,
.fast-forward-1eC-z6CY,
.volume-2gdcbXfJ,
.retry-2FkTPmFi {
width: 30px;
height: 30px;
cursor: pointer;
}
.fatal-2lTbqkU4 {
width: 30px;
height: 30px;
display: flex;
justify-content: center;
align-items: center;
}
.center-1fXFgRoW {
display: flex;
justify-content: center;
align-items: center;
height: 100%;
width: 100%;
}
.play-triangle-2g8X_Wrg,
.pause-bars-3qWQKO4b {
z-index: 2;
opacity: 1;
transform: scale(1) translateX(0);
transition: transform 300ms ease-in, opacity 300ms ease-in;
}
.play-3nZmdAx2:hover .play-triangle-2g8X_Wrg,
.active-NDVLZmwo .play-triangle-2g8X_Wrg {
transform: scale(0.5) translateX(3px);
transform-origin: center;
transition: transform 300ms ease-out;
fill: #6288a5;
}
.buffering-2eCRMkd1 .play-triangle-2g8X_Wrg {
opacity: 0.5;
transform: scale(0.5) translateX(3px);
transform-origin: center;
transition: transform 300ms ease-out, opacity 300ms ease-out,
fill 300ms ease-out;
fill: #6288a5;
}
.pause-ohgGg9mU:hover .pause-bars-3qWQKO4b,
.active-NDVLZmwo .pause-bars-3qWQKO4b {
transform: scale(0.5);
transform-origin: center;
transition: transform 300ms ease-out, fill 300ms ease-out;
fill: #6288a5;
}
.buffering-2eCRMkd1 .pause-bars-3qWQKO4b {
opacity: 0.5;
transform: scale(0.5);
transition: transform 300ms ease-out 300ms, opacity 300ms ease-out 300ms,
fill 300ms ease-out 300ms;
fill: #6288a5;
}
.spinner-3-QgGKxJ {
position: absolute;
top: 0;
right: 0;
bottom: 0;
left: 0;
z-index: 1;
opacity: 0;
transition: opacity 300ms ease-out;
box-sizing: border-box;
display: block;
height: 40px;
width: 40px;
border: 1px solid #6288a5;
border-radius: 50%;
}
.active-NDVLZmwo .spinner-3-QgGKxJ {
opacity: 1;
transition: opacity 300ms ease-out 300ms;
}
.play-3nZmdAx2:hover .spinner-3-QgGKxJ,
.pause-ohgGg9mU:hover .spinner-3-QgGKxJ {
opacity: 1;
transition: opacity 300ms ease-out;
}
.buffering-2eCRMkd1 .spinner-3-QgGKxJ {
opacity: 1;
transition: opacity 300ms ease-out 300ms;
-webkit-animation: spin-1xisgdKG 3000ms linear infinite;
animation: spin-1xisgdKG 3000ms linear infinite;
border: none;
}
@-webkit-keyframes spin-1xisgdKG {
0% {
transform: rotate(0deg);
}
100% {
transform: rotate(360deg);
}
}
@keyframes spin-1xisgdKG {
0% {
transform: rotate(0deg);
}
100% {
transform: rotate(360deg);
}
}
.spinner-3-QgGKxJ span {
display: block;
box-sizing: border-box;
position: absolute;
top: 0;
right: 0;
bottom: 0;
left: 0;
height: 40px;
width: 40px;
clip: rect(20px, 40px, 40px, 0);
opacity: 0;
-webkit-animation: none;
animation: none;
}
.buffering-2eCRMkd1 .spinner-3-QgGKxJ span {
opacity: 1;
transition: opacity 300ms ease-out;
-webkit-animation: spin-1xisgdKG 1500ms cubic-bezier(0.77, 0, 0.175, 1) infinite;
animation: spin-1xisgdKG 1500ms cubic-bezier(0.77, 0, 0.175, 1) infinite;
}
.spinner-3-QgGKxJ span::before {
content: '';
display: block;
box-sizing: border-box;
position: absolute;
top: 0;
right: 0;
bottom: 0;
left: 0;
height: 40px;
width: 40px;
border: 1px solid transparent;
border-top: 1px solid #6288a5;
border-radius: 50%;
-webkit-animation: none;
animation: none;
}
.buffering-2eCRMkd1 .spinner-3-QgGKxJ span::before {
-webkit-animation: spin-1xisgdKG 1500ms cubic-bezier(0.77, 0, 0.175, 1) infinite;
animation: spin-1xisgdKG 1500ms cubic-bezier(0.77, 0, 0.175, 1) infinite;
}
.spinner-3-QgGKxJ span::after {
content: '';
display: block;
box-sizing: border-box;
position: absolute;
top: 0;
right: 0;
bottom: 0;
left: 0;
height: 40px;
width: 40px;
border: 1px solid #6288a5;
border-radius: 50%;
}
@-webkit-keyframes fadeIn-l910csyW {
from {
opacity: 0;
}
to {
opacity: 1;
}
}
@keyframes fadeIn-l910csyW {
from {
opacity: 0;
}
to {
opacity: 1;
}
}
.duration-2IOln_4E {
font-size: 14px;
color: #666666;
text-align: right;
-webkit-user-select: none;
-moz-user-select: none;
-ms-user-select: none;
user-select: none;
opacity: 0;
-webkit-animation: fadeIn-l910csyW 400ms ease-in 600ms forwards;
animation: fadeIn-l910csyW 400ms ease-in 600ms forwards;
}
.duration-2IOln_4E.duration--placeholder-23ekiDrQ {
font-weight: 600;
-webkit-animation: none;
animation: none;
opacity: 1;
}
.timeline-FLWx8HaN {
flex-grow: 1;
cursor: pointer;
position: relative;
height: 30px;
transition: transform 400ms ease-out;
transform-origin: right;
transform: scaleX(1);
}
.timeline-FLWx8HaN.timeline--placeholder-2c56g3DK {
cursor: inherit;
}
.timeline__progress-2DxHusDz {
width: 0%;
height: 2px;
margin: 14px 0;
position: absolute;
background: #6288a5;
z-index: 3;
}
.timeline__buffered-31MAg1_h {
width: 0%;
height: 2px;
margin: 14px 0;
position: absolute;
background: #bbbbbb;
z-index: 2;
}
.timeline__duration-1zWj-_wf {
width: 100%;
height: 2px;
margin: 14px 0;
position: absolute;
background: #e2e2e2;
z-index: 1;
}
/*
* This is just used for keyboard control of the "slider"
* We have to use the ARIA slider role instead of an input
* It's just an extra <div> with some keyboard handlers and an outline
*/
.timeline__slider-1oXbNbyO:focus {
height: 2px;
width: 100%;
outline: 1px solid #4a90e2;
outline-offset: 1px;
}
.timeline__scrubber-1KW7G1LV {
opacity: 0;
position: absolute;
top: 3px;
left: 0;
z-index: 4;
transform: scale(0.1);
transform-origin: center left;
transition: opacity 150ms ease-in, transform 150ms ease-in;
}
.timeline__scrubber--scrubbing-16_Qm_Ir {
top: 10px;
}
.timeline--hovered-3hy8rDQy .timeline__scrubber-1KW7G1LV {
opacity: 1;
transform: scale(1);
transform-origin: center left;
transition: opacity 150ms ease-out, transform 150ms ease-out;
}
.timeline__scrubber-1KW7G1LV svg.scrub-indicator-PzkVedth {
margin-left: -12.5px;
}
.timeline__scrubber--scrubbing-16_Qm_Ir svg.handle-2zqBDnfr {
position: absolute;
top: 0;
left: -5px;
z-index: 5;
}
.timeline__scrubber--scrubbing-16_Qm_Ir svg.ink-2uIAwEoF {
position: absolute;
top: -15px;
left: -20px;
opacity: 0.65;
transform: scale(1);
-webkit-animation: ripple-2UbN71DW 200ms ease;
animation: ripple-2UbN71DW 200ms ease;
z-index: 4;
}
@-webkit-keyframes ripple-2UbN71DW {
from {
transform: scale(0);
}
to {
transform: scale(1);
}
}
@keyframes ripple-2UbN71DW {
from {
transform: scale(0);
}
to {
transform: scale(1);
}
}
.error-1OQiDW0M {
font-size: 14px;
color: #666666;
}
.error__message-1xpi7c0p {
display: flex;
flex-direction: column;
justify-content: center;
}
.error__message-1xpi7c0p span {
line-height: normal;
}
]]>
</style>
<style>
<![CDATA[
.vhs-plugin-browser-not-supported{position:absolute;z-index:50;background:#000;width:100%;height:100%;top:0;left:0;display:none}.vhs-plugin-browser-not-supported .vhs-plugin-browser-not-supported-message{position:relative;top:50%;-webkit-transform:translateY(-50%);-ms-transform:translateY(-50%);transform:translateY(-50%);text-align:center}.vhs-plugin-browser-not-supported .vhs-plugin-browser-not-supported-message .vhs-icon-alert{color:#fff;font-size:30px;margin-right:20px;vertical-align:middle}.vhs-plugin-browser-not-supported .vhs-plugin-browser-not-supported-message p{text-align:left;font-family:arial, helvetica, sans-serif;font-weight:400;font-size:13px;color:#fff;display:inline-block;margin:0;vertical-align:middle}.vhs-xxs .vhs-plugin-browser-not-supported .vhs-plugin-browser-not-supported-message p,.vhs-xs .vhs-plugin-browser-not-supported .vhs-plugin-browser-not-supported-message p,.vhs-s .vhs-plugin-browser-not-supported .vhs-plugin-browser-not-supported-message p{margin-top:15px;text-align:center;display:block}
]]>
</style>
<style>
<![CDATA[
@keyframes spin{to{transform:rotate(1turn)}}.vhs-buffering-container{z-index:6;position:absolute;margin:auto;top:0;left:0;right:0;bottom:0;cursor:wait}.vhs-buffering-spinner{width:5em;height:5em;text-indent:999em;animation:spin 1s infinite steps(8);font-size:8px;position:absolute;top:0;left:0;right:0;bottom:0;margin:auto}.vhs-buffering-spinner:before,.vhs-buffering-spinner:after,.vhs-buffering-spinner>div:before,.vhs-buffering-spinner>div:after{content:'';position:absolute;top:0;left:2.25em;width:0.5em;height:1.5em;border-radius:0.2em;background:#eee;box-shadow:0 3.5em #eee;transform-origin:50% 2.5em}.vhs-buffering-spinner:before{background:#555}.vhs-buffering-spinner:after{transform:rotate(-45deg);background:#777}.vhs-buffering-spinner>div:before{transform:rotate(-90deg);background:#999}.vhs-buffering-spinner>div:after{transform:rotate(-135deg);background:#bbb}
]]>
</style>
<style>
<![CDATA[
.poster-plugin-z-index-2PI2645M {
z-index: 44;
}
.captions-plugin-z-index-OjsfQXtY {
z-index: 39;
}
]]>
</style>
<style>
<![CDATA[
.container-3YGvWbv8 {
position: absolute;
bottom: 21px;
width: 100%;
pointer-events: none;
transition: bottom 0.2s 0.333s;
/**
* Force Safari on iOS 11 to redraw some elements on the DOM that were not being drawn on screen.
* @see https://davidwalsh.name/translate3d
*
* Note: I was shocked to find that `will-change: transform;` did _not_ work here.
* Both `transform: translate3d(0, 0, 0);` and the approach in the above link with
* `backface-visibility` and `perspective` worked. Here I've chosen the `transform`
* based approach since it's just one line.
*/
transform: translate3d(0, 0, 0);
}
.cueWrap-2P4Ue4VQ {
width: 68%;
margin: 0 auto;
text-align: center;
pointer-events: none;
}
.captions-2YSIFrBk {
color: white;
background-color: rgba(0, 0, 0, 0.9);
box-shadow: 9px 0 0 rgba(0, 0, 0, 0.9), -9px 0 0 rgba(0, 0, 0, 0.9);
-webkit-box-decoration-break: clone;
box-decoration-break: clone;
font-family: 'franklin', 'nyt-franklin', Arial, helvetica, sans-serif;
font-weight: 600;
font-size: 16px;
pointer-events: none;
line-height: 26px;
padding: 6px 0 4px 0;
white-space: pre-line;
}
.raised--tQnNY7r {
transition: bottom 0.2s;
}
.vhs-xxs-23weYfvK {
bottom: 10px;
}
.vhs-xs-6et0hWqr,
.vhs-s-1RsNrFsB {
bottom: 12px;
}
.vhs-xxs-23weYfvK.raised--tQnNY7r {
bottom: 34.4px;
}
.vhs-s-1RsNrFsB.raised--tQnNY7r,
.vhs-xs-6et0hWqr.raised--tQnNY7r {
bottom: 46px;
}
.vhs-m-3marGH-Z.raised--tQnNY7r {
bottom: 51.6px;
}
.vhs-xl-IRfj3CcU.raised--tQnNY7r,
.vhs-l-I7vvj8yD.raised--tQnNY7r {
bottom: 66px;
}
.vhs-xxs-23weYfvK .cueWrap-2P4Ue4VQ,
.vhs-xs-6et0hWqr .cueWrap-2P4Ue4VQ {
width: 70%;
}
.vhs-s-1RsNrFsB .cueWrap-2P4Ue4VQ,
.vhs-m-3marGH-Z .cueWrap-2P4Ue4VQ,
.vhs-l-I7vvj8yD .cueWrap-2P4Ue4VQ,
.vhs-xl-IRfj3CcU .cueWrap-2P4Ue4VQ {
max-width: 320px;
}
.vhs-xxl-1MpJ1M8o .cueWrap-2P4Ue4VQ {
max-width: 370px;
}
.vhs-xxl-1MpJ1M8o.raised--tQnNY7r {
bottom: 81.6px;
}
.vhs-xxs-23weYfvK .captions-2YSIFrBk,
.vhs-xs-6et0hWqr .captions-2YSIFrBk,
.vhs-s-1RsNrFsB .captions-2YSIFrBk {
font-size: 14px;
line-height: 21px;
padding: 4px 0 3px 0;
box-shadow: 8px 0 0 rgba(0, 0, 0, 0.9), -8px 0 0 rgba(0, 0, 0, 0.9);
}
.vhs-m-3marGH-Z .captions-2YSIFrBk,
.vhs-l-I7vvj8yD .captions-2YSIFrBk {
font-size: 16px;
line-height: 26px;
}
.vhs-xl-IRfj3CcU .captions-2YSIFrBk {
font-size: 18px;
line-height: 26px;
padding: 5px 0 3px 0;
box-shadow: 7px 0 0 rgba(0, 0, 0, 0.9), -7px 0 0 rgba(0, 0, 0, 0.9);
}
.vhs-xxl-1MpJ1M8o .captions-2YSIFrBk {
font-size: 24px;
line-height: 32px;
padding: 5px 0 3px 0;
box-shadow: 10px 0 0 rgba(0, 0, 0, 0.9), -7px 0 0 rgba(0, 0, 0, 0.9);
}
]]>
</style>
<style>
<![CDATA[
.vhs-plugin-contextual-menu{position:absolute;top:0;left:0;z-index:80;background-color:white;width:230px;-webkit-border-radius:5px;-khtml-border-radius:5px;-moz-border-radius:5px;-ms-border-radius:5px;-o-border-radius:5px;border-radius:5px;margin:0;padding:0;overflow:hidden;-webkit-box-shadow:0 5px 14px rgba(0,0,0,0.3);-khtml-box-shadow:0 5px 14px rgba(0,0,0,0.3);-moz-box-shadow:0 5px 14px rgba(0,0,0,0.3);-ms-box-shadow:0 5px 14px rgba(0,0,0,0.3);-o-box-shadow:0 5px 14px rgba(0,0,0,0.3);box-shadow:0 5px 14px rgba(0,0,0,0.3)}.vhs-plugin-contextual-menu li{background:none;list-style-type:none;margin:0;padding:8px 12px;border-bottom:1px solid #eaeaea;color:#b3b3b3;-webkit-user-select:none;-khtml-user-select:none;-moz-user-select:none;-ms-user-select:none;-o-user-select:none;user-select:none;cursor:default;font-family:'franklin', 'nyt-franklin', Arial, helvetica, sans-serif;font-size:12px;font-weight:normal}.vhs-plugin-contextual-menu li.active{color:#808080;cursor:pointer}.vhs-plugin-contextual-menu li.active:hover{color:#000000;background-color:#f0f0f0}.vhs-plugin-contextual-menu li.version{font-size:11px;padding:12px}.vhs-plugin-contextual-menu li:last-child{border-bottom:none}
]]>
</style>
<style>
<![CDATA[
.vhs-plugin-controls,.vhs-plugin-controls-gradient{-webkit-user-select:none;-khtml-user-select:none;-moz-user-select:none;-ms-user-select:none;-o-user-select:none;user-select:none;position:absolute;bottom:-1px;left:0;right:0;pointer-events:none;transition:bottom 0.3s, opacity 0.3s}.vhs-plugin-controls-gradient{z-index:38;background-color:transparent;background-image:linear-gradient(transparent, rgba(0,0,0,0.7));background-repeat:no-repeat;opacity:0;transition:opacity 0.4s ease-in-out;-moz-transition:opacity 0.4s ease-in-out;-webkit-transition:opacity 0.4s ease-in-out}.vhs-plugin-controls-gradient.vhs-controls-hidden{opacity:0}.vhs-plugin-controls-gradient.vhs-controls-active{opacity:1}.vhs-plugin-controls{-webkit-user-select:none;-khtml-user-select:none;-moz-user-select:none;-ms-user-select:none;-o-user-select:none;user-select:none;z-index:40;position:absolute;bottom:-1px;left:0;right:0;pointer-events:none;font-size:1.3em;transition:bottom 0.3s, opacity 0.3s;line-height:normal;display:none;align-items:center;color:white}.vhs-plugin-controls [class^='vhs-icon-'],.vhs-plugin-controls [class*=' vhs-icon-'],.vhs-plugin-controls [class^='vhs-icon-']:before,.vhs-plugin-controls [class*=' vhs-icon-']:before{width:auto;font-size:1em;font-family:'vhs'}.vhs-plugin-controls.vhs-controls-enabled{display:-webkit-box !important;display:-moz-box !important;display:-ms-flexbox !important;display:-webkit-flex !important;display:flex !important}.vhs-plugin-controls.vhs-controls-hidden{opacity:0;transition:opacity 0.4s ease-in-out;-moz-transition:opacity 0.4s ease-in-out;-webkit-transition:opacity 0.4s ease-in-out}.vhs-plugin-controls.vhs-controls-active{opacity:1;transition:opacity 0.4s ease-in-out;-moz-transition:opacity 0.4s ease-in-out;-webkit-transition:opacity 0.4s ease-in-out}.vhs-plugin-controls-message-container{display:none}.vhs-plugin-controls-message-container .vhs-plugin-controls-ad-label,.vhs-plugin-controls-message-container .vhs-plugin-controls-live-label{display:none;align-items:center}.vhs-plugin-controls-message-container .vhs-plugin-controls-live-circle{float:left;border-radius:50%;width:10px;height:10px;display:inline;background:red;margin:0 7px 0px 0px}.vhs-plugin-controls-play-container,.vhs-plugin-controls-progress,.vhs-plugin-controls-options-container{display:inline-block;pointer-events:auto;-webkit-align-self:center}.vhs-plugin-controls-play-container{-moz-box-ordinal-group:1;-ms-flex-order:1;-webkit-order:1;order:1;height:0;text-align:center;line-height:1;cursor:pointer;width:1.3em}.vhs-plugin-controls-play-container .vhs-plugin-controls-play{position:relative;bottom:0.55em;font-size:1.3em;color:white}.vhs-plugin-controls-play-container .vhs-plugin-controls-play.vhs-icon-play:before{content:'\e81c'}.vhs-plugin-controls-play-container .vhs-plugin-controls-play.vhs-icon-pause:before{content:'\e81d'}.vhs-plugin-controls-message-container{-webkit-box-flex:1;-moz-box-flex:1;-webkit-flex:1;-ms-flex:1;flex:1;-moz-box-ordinal-group:2;-ms-flex-order:2;-webkit-order:2;order:2;font-size:13px;font-family:'franklin', 'nyt-franklin', sans-serif;color:#b5b5b5;display:none;letter-spacing:0.3px;font-weight:bold}.vhs-plugin-controls-message-container.vhs-message-container-enabled{display:-webkit-box;display:-moz-box;display:-ms-flexbox;display:-webkit-flex;display:flex}.nytd-player-ad-controls .vhs-plugin-controls-message-container{display:block}.nytd-player-ad-controls .vhs-plugin-controls-message-container .vhs-plugin-controls-ad-label{display:block}.vhs-plugin-controls-progress{-webkit-box-flex:1;-moz-box-flex:1;-webkit-flex:1;-ms-flex:1;flex:1;-moz-box-ordinal-group:3;-ms-flex-order:3;-webkit-order:3;order:3;display:-webkit-box;display:-moz-box;display:-ms-flexbox;display:-webkit-flex;display:flex;align-items:center;cursor:pointer}.vhs-plugin-controls-progress.vhs-progress-hidden{display:none}.vhs-plugin-controls-progress .vhs-plugin-controls-current-time,.vhs-plugin-controls-progress .vhs-plugin-controls-duration{font:normal bold 10px/1 'franklin', 'nyt-franklin', sans-serif;cursor:default}.vhs-plugin-controls-progress .vhs-plugin-controls-progress-timeline{position:relative;-webkit-box-flex:1;-moz-box-flex:1;-webkit-flex:1;-ms-flex:1;flex:1;align-items:center;margin-right:15px;display:block;box-sizing:border-box;background-color:#000;border-radius:100px;padding:2px}.vhs-plugin-controls-progress .vhs-plugin-controls-progress-slider{position:absolute;top:2px;left:2px;right:2px;bottom:2px}.vhs-plugin-controls-progress .vhs-plugin-controls-progress-slider:focus{outline:none}.vhs-plugin-controls-progress .vhs-plugin-controls-progress-buffer,.vhs-plugin-controls-progress .vhs-plugin-controls-progress-time{display:block;height:100%;position:absolute;background-color:rgba(255,255,255,0.4);border-radius:100px}.vhs-plugin-controls-progress .vhs-plugin-controls-progress-time{background-color:rgba(255,255,255,0.7)}.vhs-plugin-controls-progress .vhs-plugin-controls-progress-marker{position:absolute;font-size:0.8em;top:50%;text-shadow:0 0 7px rgba(0,0,0,0.6);-moz-transform:translate(-50%, -50%);-o-transform:translate(-50%, -50%);-ms-transform:translate(-50%, -50%);-webkit-transform:translate(-50%, -50%);transform:translate(-50%, -50%);opacity:0;transition:opacity 300ms ease-out;z-index:1}.vhs-plugin-controls-progress .vhs-plugin-controls-progress-marker.vhs-icon-circle:before{content:'\e81e'}.vhs-plugin-controls-progress .vhs-plugin-controls-progress-marker:before{transition:transform 0.3s}.vhs-plugin-controls-progress .vhs-plugin-controls-progress-marker:after{content:'';width:20px;height:20px;left:22px;top:10px;opacity:0;position:absolute;border:2px solid rgba(255,255,255,0.5);transform:translate(-26px, -13px);border-radius:50%;z-index:-1;transition:opacity 0.3s}.vhs-plugin-controls-progress .vhs-plugin-controls-progress-marker.vhs-plugin-controls-progress-marker--active{opacity:1;transition:opacity 300ms ease-in}.vhs-plugin-controls-progress input[type='range']{width:100%;height:100%;border:none;background:transparent;position:absolute;top:0;right:0;bottom:0;left:0;margin:0;-webkit-appearance:none;z-index:0}.vhs-plugin-controls-progress input[type='range']::-ms-tooltip{display:none}.vhs-plugin-controls-progress input[type='range']::-webkit-slider-thumb{-webkit-appearance:none;height:100%;width:1px;background:transparent;cursor:pointer;margin-top:0}.vhs-plugin-controls-progress input[type='range']::-moz-range-thumb{height:100%;width:1px;background:transparent;cursor:pointer}.vhs-plugin-controls-progress input[type='range']::-ms-thumb{height:100%;width:1px;background:transparent;cursor:pointer}.vhs-plugin-controls-progress input[type='range']::-webkit-slider-runnable-track{width:100%;height:100%;cursor:pointer;background:transparent;border-radius:2px}.vhs-plugin-controls-progress input[type='range']::-moz-range-track{width:100%;height:100%;cursor:pointer;background:transparent;border-radius:2px}.vhs-plugin-controls-progress input[type='range']::-ms-track{width:100%;height:100%;cursor:pointer;background:transparent;border-color:transparent;border-radius:2px;color:transparent}.vhs-controls-no-touch .vhs-plugin-controls-progress-slider:focus{outline:1px solid #4a90e2;outline-offset:1px}.vhs-plugin-controls-options-container{display:-webkit-box;display:-moz-box;display:-ms-flexbox;display:-webkit-flex;display:flex;-moz-box-ordinal-group:4;-ms-flex-order:4;-webkit-order:4;order:4}.vhs-plugin-controls-options-container .vhs-plugin-controls-option{font-family:'vhs';display:inline-block;width:auto;text-align:center;cursor:pointer;color:rgba(255,255,255,0.8)}.vhs-plugin-controls-options-container .vhs-plugin-controls-option:hover,.vhs-plugin-controls-options-container .vhs-plugin-controls-option:focus{color:white}.vhs-plugin-controls-options-container .vhs-plugin-controls-option:last-child{margin-right:0}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-icon-resize-full:before{content:'\e809'}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-icon-resize-default:before{content:'\e812'}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-icon-reload:before{content:'\e804'}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-icon-gear:before{content:'\e816'}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-icon-cc-disabled{display:none}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-icon-cc-on:before,.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-icon-cc-off:before{content:'\e807'}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-icon-cc-on{color:#fff}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-icon-cc-off{color:rgba(255,255,255,0.3)}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-icon-cc-off:hover,.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-icon-cc-off:focus{color:rgba(255,255,255,0.5)}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-plugin-controls-transcript{opacity:0.8}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-plugin-controls-transcript .vhs-icon-transcript-container{display:flex;justify-content:center;align-items:center;height:100%;width:100%}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-plugin-controls-transcript:hover{opacity:1}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-icon-transcript-disabled,.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-icon-transcript-hidden{display:none}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-plugin-controls-volume-container{position:relative}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-plugin-controls-volume-container .vhs-plugin-controls-volume{font-family:'vhs';color:rgba(255,255,255,0.8)}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-plugin-controls-volume-container .vhs-plugin-controls-volume.vhs-icon-volume-off:before{content:'\e811'}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-plugin-controls-volume-container .vhs-plugin-controls-volume.vhs-icon-volume-on:before{content:'\e80a'}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-plugin-controls-volume-container .vhs-plugin-controls-volume.vhs-icon-volume-half:before{content:'\e813'}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-plugin-controls-volume-container .vhs-plugin-controls-volume:hover,.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-plugin-controls-volume-container .vhs-plugin-controls-volume:focus{color:white}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-plugin-controls-volume-container .vhs-plugin-controls-volume-slider-container{padding-top:150%;padding-left:105%;position:absolute;top:140%;left:-23%;transform:rotate(270deg);transform-origin:top left;background-color:rgba(0,0,0,0.27);border-radius:2px;z-index:-1;backface-visibility:hidden;opacity:0}@keyframes show-volume-slider-container{0%{width:135px}1%{width:135px;opacity:0}100%{width:135px;opacity:1}}@keyframes hide-volume-slider-container{0%{width:135px;opacity:1}99%{width:135px;opacity:0}100%{width:0}}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-plugin-controls-volume-container .vhs-plugin-controls-volume-slider-container.vhs-plugin-controls-volume-slider-show{animation:show-volume-slider-container 300ms ease-out forwards}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-plugin-controls-volume-container .vhs-plugin-controls-volume-slider-container.vhs-plugin-controls-volume-slider-hide{animation:hide-volume-slider-container 300ms ease-in forwards}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-plugin-controls-volume-container .vhs-plugin-controls-volume-slider-container .vhs-plugin-controls-volume-slider-track{height:3px;width:65%;border-radius:2px;background:transparent;position:absolute;top:0;right:15px;bottom:0;z-index:1;margin:auto}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-plugin-controls-volume-container .vhs-plugin-controls-volume-slider-container .vhs-plugin-controls-volume-slider-track .vhs-plugin-controls-volume-slider-fill{width:100%;height:100%;background:white;border-radius:2px}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-plugin-controls-volume-container .vhs-plugin-controls-volume-slider-container input[type='range']{width:65%;height:5px;border:1px solid white;border-radius:2px;background:transparent;position:absolute;top:0;right:15px;bottom:0;margin:auto;z-index:2;-webkit-appearance:none}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-plugin-controls-volume-container .vhs-plugin-controls-volume-slider-container input[type='range']::-ms-tooltip{display:none}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-plugin-controls-volume-container .vhs-plugin-controls-volume-slider-container input[type='range']::-webkit-slider-thumb{-webkit-appearance:none;height:100%;width:1px;background:transparent;cursor:pointer;margin-top:0}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-plugin-controls-volume-container .vhs-plugin-controls-volume-slider-container input[type='range']::-moz-range-thumb{height:100%;width:1px;background:transparent;cursor:pointer}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-plugin-controls-volume-container .vhs-plugin-controls-volume-slider-container input[type='range']::-ms-thumb{height:100%;width:1px;background:transparent;cursor:pointer}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-plugin-controls-volume-container .vhs-plugin-controls-volume-slider-container input[type='range']::-webkit-slider-runnable-track{width:100%;height:3px;cursor:pointer;background:transparent;border-radius:2px}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-plugin-controls-volume-container .vhs-plugin-controls-volume-slider-container input[type='range']::-moz-range-track{width:100%;height:3px;cursor:pointer;background:transparent;border-radius:2px}.vhs-plugin-controls-options-container .vhs-plugin-controls-option.vhs-plugin-controls-volume-container .vhs-plugin-controls-volume-slider-container input[type='range']::-ms-track{width:100%;height:3px;cursor:pointer;background:transparent;border-color:transparent;border-radius:2px;color:transparent}
]]>
</style>
<style>
<![CDATA[
.vhs-copy-slate{position:absolute;top:0;right:0;bottom:0;left:0;z-index:60;background:rgba(0,0,0,0.8)}.vhs-copy-slate .vhs-copy-slate-close-button{box-sizing:content-box;display:block;font-size:20px;font-style:normal;line-height:1;color:#fff;position:absolute;top:-10px;right:-10px;width:35px;height:35px;margin:15px;cursor:pointer;opacity:0.8;-moz-transition:opacity 0.3s ease-in-out;-o-transition:opacity 0.3s ease-in-out;-webkit-transition:opacity 0.3s ease-in-out;transition:opacity 0.3s ease-in-out}.vhs-copy-slate .vhs-copy-slate-close-button .vhs-copy-slate-close-button-x{margin:5px}.vhs-copy-slate .vhs-copy-slate-close-button:hover,.vhs-copy-slate .vhs-copy-slate-close-button:focus{opacity:1}.vhs-copy-slate .vhs-copy-slate-close-button:focus{outline:1px solid #4a90e2;outline-offset:1px}.vhs-copy-slate .vhs-copy-slate-center-container{position:absolute;top:0;right:0;bottom:0;left:0;margin:auto;padding:20px;height:110px;width:65%;max-width:500px;overflow:hidden}.vhs-copy-slate .vhs-copy-slate-center-container h4{margin:0 0 10px 0;padding:0;font-family:'franklin', 'nyt-franklin', Arial, helvetica, sans-serif;font-size:14px;font-weight:700;color:#fff}.vhs-copy-slate .vhs-copy-slate-center-container p{font-family:'franklin', 'nyt-franklin', Arial, helvetica, sans-serif;font-size:14px;font-weight:500;color:#fff}.vhs-copy-slate .vhs-copy-slate-center-container .vhs-embed-form-container{position:relative}.vhs-copy-slate .vhs-copy-slate-center-container .vhs-embed-form-container input{width:100%;height:auto;box-sizing:border-box;margin:0;padding:10px;border-radius:3px;border:2px solid #ffffff;overflow:hidden;font-family:'franklin', 'nyt-franklin', Arial, helvetica, sans-serif;font-size:12px;font-weight:normal;color:#000}.vhs-copy-slate .vhs-copy-slate-center-container .vhs-embed-form-container input:focus{outline:none;border-color:#44cafc}.vhs-copy-slate .vhs-copy-slate-center-container .vhs-embed-form-container:after{content:'';position:absolute;right:3px;top:3px;height:80%;width:70%;border-radius:3px;background-image:-webkit-linear-gradient(right, #fff, rgba(255,255,255,0));background-image:-moz-linear-gradient(right, #fff, rgba(255,255,255,0));background-image:-ms-linear-gradient(right, #fff, rgba(255,255,255,0));background-image:-o-linear-gradient(right, #fff, rgba(255,255,255,0));background-image:linear-gradient(right, #fff, rgba(255,255,255,0));filter:progid:DXImageTransform.Microsoft.gradient( GradientType=0, StartColorStr='#FFFFFFFF', EndColorStr='#00FFFFFF' );pointer-events:none}
]]>
</style>
<style>
<![CDATA[
.vhs-plugin-error-slate{display:none;width:100%;height:100%;position:absolute;background:#000;line-height:1;-webkit-touch-callout:none;-webkit-user-select:none;-khtml-user-select:none;-moz-user-select:none;-ms-user-select:none;-o-user-select:none;user-select:none;z-index:50}.vhs-plugin-error-slate .vhs-plugin-error{display:block;font-family:'franklin', 'nyt-franklin', arial, helvetica, sans-serif;font-size:13px;font-weight:700;text-align:center;color:#fff;z-index:50;position:relative;top:50%;-webkit-transform:translateY(-50%);-ms-transform:translateY(-50%);transform:translateY(-50%)}.vhs-plugin-error-slate .vhs-plugin-error .vhs-plugin-error-reload-icon{cursor:pointer;color:#fff;font-family:vhs;font-size:17px;margin-right:5px}.vhs-plugin-error-slate .vhs-plugin-error .vhs-plugin-error-reload-icon:before{content:'\e804'}.vhs-plugin-error-slate .vhs-plugin-error .vhs-icon-alert{color:#fff;font-family:vhs;font-size:22px;margin-right:5px;display:none}.vhs-plugin-error-slate .vhs-plugin-error .vhs-icon-alert:before{width:1.1em}.vhs-plugin-error-slate .vhs-plugin-error .vhs-plugin-error-msg{display:inline-block}
]]>
</style>
<style>
<![CDATA[
@-webkit-keyframes fade-in-1mDrHEhL {
from {
opacity: 0;
}
to {
opacity: 1;
}
}
@keyframes fade-in-1mDrHEhL {
from {
opacity: 0;
}
to {
opacity: 1;
}
}
.overlay-19fDZ37B {
position: absolute;
height: 100%;
width: 100%;
/* Matches `$zindex-controls` in `src/stylesheet/z-index.scss` */
z-index: 40;
-webkit-animation: fade-in-1mDrHEhL 500ms ease-out forwards;
animation: fade-in-1mDrHEhL 500ms ease-out forwards;
display: flex;
justify-content: center;
align-items: center;
background-color: transparent;
border: none;
}
.unmuteCta-2JotPa9b {
color: white;
font-weight: 700;
font-size: 14px;
line-height: 16px;
display: flex;
align-items: center;
background-color: #0000006b;
padding: 10px 15px;
border-radius: 3px;
display: flex;
align-items: center;
}
.cta-2ofTjDz9 {
text-transform: uppercase;
margin-top: 2px;
}
.volume-1_GozD1r {
margin-right: 10px;
display: flex;
}
.volume-1_GozD1r svg {
fill: white;
}
.volume-1_GozD1r svg path {
stroke: white;
}
.liveBadge-2VLT13-_ {
display: inline-block;
font-size: 14px;
font-weight: 700;
padding: 4px 8px 3px;
color: #fff;
background-color: #d11e26;
border-radius: 3px;
text-transform: uppercase;
position: absolute;
top: 15px;
right: 15px;
}
]]>
</style>
<style>
<![CDATA[
.overlay{position:absolute;height:100%;width:100%;z-index:40;display:flex;justify-content:flex-start;align-items:flex-end;background-color:transparent;border:none;padding:12px 16px}.unmuteIconWrapper{display:flex;align-items:center;justify-content:center;position:relative;height:40px;width:40px}.backgroundCircle{position:absolute;background-color:#000;opacity:50%;border-radius:50%;height:100%;width:100%}.volume-muted{background-image:url("data:image/svg+xml,%3Csvg width='24' height='20' viewBox='0 0 24 20' fill='none' xmlns='http://www.w3.org/2000/svg'%3E%3Cpath d='M21.333 10L24 7.333L22.667 6L20 8.667L17.333 6L16 7.333L18.667 10L16 12.667L17.333 14L20 11.333L22.667 14L24 12.667L21.333 10ZM11 0H13V20H11V0ZM11 20L1 10L11 0' fill='white'/%3E%3Cpath d='M0 6H10V14H0V6Z' fill='white'/%3E%3C/svg%3E%0A");background-position:center center;background-repeat:no-repeat;width:100%;height:100%;z-index:1}
]]>
</style>
<style>
<![CDATA[
.nyt-debate-unmute{bottom:0;background-image:url("data:image/png;base64,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");background-position:center center;background-repeat:no-repeat;background-size:45px auto;height:45px;left:auto;opacity:0.4;padding:8px 15px;position:absolute;text-indent:-9999px;transition:0.35s ease-out;width:45px;z-index:9999;top:0}.nyt-debate-unmute.mute{background-image:url("data:image/png;base64,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")}.nyt-debate-unmute:hover{cursor:pointer;opacity:1}
]]>
</style>
<style>
<![CDATA[
.vhs-plugin-orientation{width:100%;height:50%;position:absolute;bottom:0;pointer-events:none}.vhs-plugin-orientation:before{position:absolute;top:0;left:0;background:linear-gradient(transparent, rgba(0,0,0,0.5));content:'';width:100%;height:100%;transition:opacity 0.3s;opacity:0}.vhs-plugin-orientation.vhs-plugin-orientation-onboarding-message-showing:before{opacity:1}.vhs-plugin-orientation-icon{z-index:99;position:absolute;height:75px;width:75px;right:2%;bottom:12%;opacity:1;pointer-events:auto}.vhs-plugin-orientation-icon.vhs-plugin-orientation-icon-faded{opacity:0.6}.vhs-plugin-orientation-icon.vhs-plugin-orientation-icon-hidden{opacity:0;pointer-events:none;cursor:auto}.vhs-plugin-orientation-icon:hover{cursor:pointer}.vhs-xxs .vhs-plugin-orientation-icon,.vhs-xs .vhs-plugin-orientation-icon,.vhs-s .vhs-plugin-orientation-icon{height:40px;width:40px;bottom:20px;right:15px}.vhs-xxs .vhs-plugin-orientation-icon .vhs-plugin-orientation-clipper,.vhs-xs .vhs-plugin-orientation-icon .vhs-plugin-orientation-clipper,.vhs-s .vhs-plugin-orientation-icon .vhs-plugin-orientation-clipper{border:2px solid white}.vhs-xxs .vhs-plugin-orientation-icon .vhs-plugin-orientation-eyes:before,.vhs-xs .vhs-plugin-orientation-icon .vhs-plugin-orientation-eyes:before,.vhs-s .vhs-plugin-orientation-icon .vhs-plugin-orientation-eyes:before{left:40%}.vhs-xxs .vhs-plugin-orientation-icon .vhs-plugin-orientation-eyes:before,.vhs-xxs .vhs-plugin-orientation-icon .vhs-plugin-orientation-eyes:after,.vhs-xs .vhs-plugin-orientation-icon .vhs-plugin-orientation-eyes:before,.vhs-xs .vhs-plugin-orientation-icon .vhs-plugin-orientation-eyes:after,.vhs-s .vhs-plugin-orientation-icon .vhs-plugin-orientation-eyes:before,.vhs-s .vhs-plugin-orientation-icon .vhs-plugin-orientation-eyes:after{height:3px;width:3px}.vhs-s .vhs-plugin-orientation-icon.vhs-plugin-orientation-raised,.vhs-xs .vhs-plugin-orientation-icon.vhs-plugin-orientation-raised{bottom:46px}.vhs-s .vhs-plugin-orientation-onboarding.vhs-plugin-orientation-raised,.vhs-xs .vhs-plugin-orientation-onboarding.vhs-plugin-orientation-raised{bottom:56px}.vhs-m .vhs-plugin-orientation-icon{height:60px;width:60px;right:17px}.vhs-m .vhs-plugin-orientation-icon.vhs-plugin-orientation-raised{bottom:52px}.vhs-m .vhs-plugin-orientation-icon .vhs-plugin-orientation-fov{right:25%}.vhs-m .vhs-plugin-orientation-onboarding.vhs-plugin-orientation-raised{bottom:62px}.vhs-l .vhs-plugin-orientation-icon{height:65px;width:65px;right:23px}.vhs-l .vhs-plugin-orientation-icon.vhs-plugin-orientation-raised{bottom:66px}.vhs-l .vhs-plugin-orientation-onboarding.vhs-plugin-orientation-raised{bottom:76px}.vhs-xl .vhs-plugin-orientation-icon{height:70px;width:70px;right:23px}.vhs-xl .vhs-plugin-orientation-icon.vhs-plugin-orientation-raised{bottom:66px}.vhs-xl .vhs-plugin-orientation-onboarding.vhs-plugin-orientation-raised{bottom:76px}.vhs-xxl .vhs-plugin-orientation-icon{height:75px;width:75px;right:30px}.vhs-xxl .vhs-plugin-orientation-icon.vhs-plugin-orientation-raised{bottom:82px}.vhs-xxl .vhs-plugin-orientation-onboarding.vhs-plugin-orientation-raised{bottom:92px}.vhs-plugin-orientation-rotator{position:relative;width:100%;height:100%}.vhs-plugin-orientation-clipper{position:relative;height:100%;width:100%;border:2px solid white;box-sizing:border-box;border-radius:100%;background:transparent;overflow:hidden}.vhs-plugin-orientation-fov{position:relative;height:75%;width:75%;transform-origin:bottom right;bottom:33%;right:24%;background-image:radial-gradient(circle at 100% 100%, rgba(255,255,255,0.7) 8%, rgba(255,255,255,0) 39%);transform:rotate(45deg)}.vhs-plugin-orientation-eyes{width:100%;height:100%;position:absolute;top:0}.vhs-plugin-orientation-eyes.vhs-plugin-orientation-blink:before,.vhs-plugin-orientation-eyes.vhs-plugin-orientation-blink:after{animation:'blink';-webkit-animation:'blink';animation-duration:1s;-webkit-animation-duration:1s;animation-iteration-count:2;-webkit-animation-iteration-count:2;animation-delay:1s;-webkit-animation-delay:1s;animation-timing-function:linear;-webkit-animation-timing-function:linear}@-webkit-keyframes blink{16%{transform:rotateX(80deg)}33%{transform:rotateX(0deg)}}.vhs-plugin-orientation-eyes:before{left:43%}.vhs-plugin-orientation-eyes:after{left:54%}.vhs-plugin-orientation-eyes:before,.vhs-plugin-orientation-eyes:after{width:4px;height:4px;position:absolute;top:50%;background:white;border-radius:100%;display:inline-block;content:'';transition:transform 0.1s}.vhs-plugin-orientation-icon{transition:bottom 0.2s, opacity 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Transcript: Ezra Klein Interviews Patrick Collison
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<time class="css-1g7pp1u e16638kd0" datetime="2022-09-27T12:25:17-04:00">Sept. 27, 2022</time>
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Real conversations. Ideas that matter. So many book recommendations.<br />
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Every Tuesday and Friday, Ezra Klein invites you into a conversation about something that matters, like todays episode with Patrick Collison. Listen <a class="css-yywogo" href="https://www.nytimes.com/2021/01/19/opinion/how-to-listen-ezra-klein-show-nyt.html" title="">wherever you get your podcasts</a>.
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We Know Shockingly Little About What Makes Humanity Prosper
</h3><span class="css-1xr8za4">Patrick Collison calls for a new “science of progress.”</span>
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transcript
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<h2 class="css-9wqu2x">
We Know Shockingly Little About What Makes Humanity Prosper
</h2>
<h4 class="css-qsd3hm">
Patrick Collison calls for a new “science of progress.”
</h4>
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<dl class="css-p98d0w">
<dt class="css-xx7kwh">
ezra klein
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
Im Ezra Klein. This is “The Ezra Klein Show.”
</p>
<p class="css-8hvvyd">
This is a great conversation today. But its a tricky one to introduce, because the guest I have — Im not having him on for the thing hes best known for. So Patrick Collison — by day, co-founder and C.E.O. of the multibillion-dollar payments company, Stripe; by night, by weekend, I think, one of the most important thinkers now in Silicon Valley — certainly, one of the most quietly influential, someone who is forging and traversing an intellectual path that a lot of other people are now following.
</p>
<p class="css-8hvvyd">
And its this second incarnation and role that Im really interviewing him in today — the soft power side, I guess, of Patrick Collison. Collisons work here centers around this question of progress. The argument is that human progress is much more precious and rare and fragile than we realize.
</p>
<p class="css-8hvvyd">
We maybe take it for granted. We live in this time when things have been changing, atop decades and decades, even centuries and centuries, even millennia now, when things have kept changing. But for most of human history, that was not true. It was not true.
</p>
<p class="css-8hvvyd">
There just was no market rapid advance in human living standards. Its only in the past 10,000 years, and then practically in the past few hundred — just an eye-blink in the time human beings have been on Earth — that things kept changing, usually for the better. And the question is, why?
</p>
<p class="css-8hvvyd">
And Collisons particular meta question is, given the clear fragility of forward motion here, given how rare it has proven to be — and so how easy it might be to lose — why isnt the question of the conditions of progress more central? Why isnt the study of progress in a wide multidisciplinary way a more common and central discipline?
</p>
<p class="css-8hvvyd">
Collison has written a few influential essays here, with the economist Tyler Cowen. He called for the inauguration of a discipline — they call it progress studies — and that now has people studying it. Theres people creating journals for it, creating syllabi and podcasts and books around the topic. Its one of the more singularly successful calls for a research direction I have seen.
</p>
<p class="css-8hvvyd">
Separately, in a piece co-authored with the scientist, Michael Nielsen, Collison and Nielsen argued that, though it is hard to measure, it seems like the rate of scientific progress is slowing down, and thats particularly true if you account for how much more were putting into science, in terms of money, of people, of time and technology.
</p>
<p class="css-8hvvyd">
Now, these ideas are not original to Collison. The point is not that nobody studied human progress before this or worried about the pace of scientific research. He wouldnt claim that. It wouldnt be true. But he is playing a distinctive role in their framing and their popularization, and in creating and funding a community around them.
</p>
<p class="css-8hvvyd">
And what I see in my travels here is that it is working. Something is burbling here. But I cant find many big pieces where Collison really lays out his worldview. There are a couple essays, tweets, interviews, but hes not been primarily writing this down.
</p>
<p class="css-8hvvyd">
What he has been doing is funding it through Fast Grants, which has been successful, but more than that, intellectually influential effort to show you can give out scientific grants quickly and with very little overhead, through the Arc Institute, a big biotech organization hes creating to push a researcher-first approach to biotech, and through giving a bit of money, and a bit of time, and a bit of prestige, and a bit of networking to a lot of different projects that circle these questions.
</p>
<p class="css-8hvvyd">
Hes got this funny quality of being nowhere in particular, but also somehow, almost everywhere, if youre interested in these questions. So what I wanted to do in this conversation was try to get as close as I could to the Patrick Collison worldview, the underlying theory of the case here that animates his thinking his funding, and the ways in which hes trying to nudge the culture hes a part of, or the ways in which hes trying to actively create a culture he doesnt yet see.
</p>
<p class="css-8hvvyd">
As always, my email — ezrakleinshow@nytimes.com.
</p>
<p class="css-8hvvyd">
Patrick Collison, welcome to the show.
</p>
</dd>
<dt class="css-xx7kwh">
patrick collison
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
Great to be back.
</p>
</dd>
<dt class="css-xx7kwh">
ezra klein
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
So youve made the argument that science — all science — is slowing down, that were putting more money and more people into research, and were getting less and less out of it. Tell me about that.
</p>
</dd>
<dt class="css-xx7kwh">
patrick collison
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
Well, I want to separate two things. Theres a question as to whether science in its totality is slowing down, in terms of the absolute returns from it. I think that might be true. You can maybe divide up the first half of the 20th century and the second half and so on, and sort of try to compare one with the other.
</p>
<p class="css-8hvvyd">
And we had general relativity and quantum mechanics and various other major breakthroughs in the first half. You can ask the question of, well, did we have as many in the second half? But in the second half, we did have the discovery of D.N.A. and molecular biology and lots of other things. So I dont know that I would claim a total slowdown. The thing that I think is clearer and should be very concerning to us is, as you look at the number of scientists engaged in the pursuit of science, and if you look at the total amount that were spending, and as you look at the total output, as coarsely measured by things like papers and number of journals, all of those metrics have grown by, depending on the number, lets say, between 20 and 100x between 1950 and, say, 2010.
</p>
<p class="css-8hvvyd">
And if you look at it on a per-capita basis, or a per-unit-of-work basis, now used to divide all those total outcomes by a factor of 50, and it seems like if you imagine yourself as the median scientist, youre meaningfully less likely to produce anything like as consequential a breakthrough as you would have, say, in 1920. And so Michael Nielsen and I, in order to try to put slightly more rigor on that question — we went and we surveyed a bunch of scientists across a number of universities in a number of different disciplines, and we presented them with different Nobel Prize-winning breakthroughs.
</p>
<p class="css-8hvvyd">
And we tried to compute an approximate ordering of their significance in the eyes of these scientists. And the thing that would kind of have to be true — for the per-capita impact, we remain in constant — is wed have to be discovering much more important things in the latter half of the 20th century in order to compensate for, to make it worthwhile, for us to be investing this 50-fold greater effort.
</p>
<p class="css-8hvvyd">
And we didnt find that. In physics, in the estimation of physicists, there was a kind of flat-to-declining trend. Its not super obvious which way it points, but in as much as theres a trend visible, its probably slightly downwards. And in other fields, it was maybe similarly equivocal, perhaps a slight increase, visible in some, but importantly, in no fields that it looked like were on this crazy, exponentially improving trajectory, which is what you would have to have for this per-capita phenomenon to not be present. And I think that should be something were interested in for multiple reasons. One, because presumably, as a society, were interested in just how much more scientific progress and technological progress and so forth, how much more innovation is there going to be over the next 10 years or the next 50 years or the next century. But also, because theres kind of two possibilities. One possibility is, fundamentally, were running out of low-hanging fruit, and its just going to be harder to do this stuff.
</p>
<p class="css-8hvvyd">
And in as much as were setting investment or making investment decisions around to what degree should be pursuing the stuff, I guess its important to know what we think the returns should be. Or the other possibility is, somehow, were doing it suboptimally. Something changed, and we were pursuing this process of discovery more effectively in the past, and presumably, for inadvertent reasons, something went wrong, and now, were just less efficient at it.
</p>
<p class="css-8hvvyd">
But either explanation — and it doesnt necessarily have to be fully binary — but either explanation is important, and either explanation, I think, has prescriptions for what we should do going forward.
</p>
</dd>
<dt class="css-xx7kwh">
ezra klein
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
Let me start with the low-hanging-fruit explanation, which I think is a more popular one. And you have — in the piece you did on this with Michael Nielsen, the sad, but in the very academic way, very funny quote from the physicist Paul Dirac, who says of the 1920s, there was a time when, quote, “Even second-rate physicists could make first-rate discoveries,” which I just kind of love.
</p>
<p class="css-8hvvyd">
But the theory there is you can only make a lot of the big discoveries once. You discover quantum mechanics once. You discover the atom once. And most of them have just been made, so what you have now is more complicated, smaller, requires much larger teams of people, much more complicated experiments, with much more infrastructure.
</p>
<p class="css-8hvvyd">
So were just structurally in a period where its going to get harder and harder and harder to make big gains. Do you believe that?
</p>
</dd>
<dt class="css-xx7kwh">
patrick collison
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
I think its possible, but even though its intuitively compelling on some level, Im not sure that its true. Its probably true to at least some degree for some particular research direction, right? We go after discovering the various subatomic particles, and initially, without too much difficulty, we discover the electron or whatever.
</p>
<p class="css-8hvvyd">
And by the time weve discovered the nth quark, its now gotten super hard, and even with ever-larger particle accelerators, were not necessarily making breakthroughs of the same magnitude. So I think its pretty true for a given direction. But obviously, the question is, well, to what degree is progress in any area opening up other directions, right?
</p>
<p class="css-8hvvyd">
And so I mean, you mentioned the Dirac quote and, say, physics in the early part of the 20th century. Those discoveries opened up new techniques and investigation methodologies and so on, that then gave rise to molecular biology in the 50s, 60s and 70s. And so theres kind of a combinatorial benefit, where discoveries over here or discoveries over there might unlock opportunities and major breakthroughs in areas that we could not have foreseen in advance.
</p>
<p class="css-8hvvyd">
There are lots of, quote unquote, “low-hanging-fruit discoveries” made in computers and computer science in the 70s, 80s, and 90s. Maybe were even still in that regime, right? Were still making some pretty fundamental breakthroughs. And of course, again, those, quote, “low-hanging discoveries” would not have been possible without a lot of this optimization and discovery in other fields.
</p>
<p class="css-8hvvyd">
And so I think its probably true for a given research direction, but the relevant question for society is, is it true in aggregate. And there, its much less clear to me that it is.
</p>
</dd>
<dt class="css-xx7kwh">
ezra klein
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
I want to read something provocative you said in an interview with the economist Noah Smith. And you said, quote, “Most systems get worse in at least certain ways as they scale. The idea that science could have gotten worse in significant ways sometimes sounds strange to people. Like, were doing so much more. How could that be bad? But I think that misses the many examples of sensitivity of scientific processes to institutions and culture. Swiss nationals have won more than 10 times more science Nobels per capita than Italians have. 10 times. And yet, theyre neighbors. And Italy certainly isnt lacking in scientific tradition — Fermi, Galileo, the oldest university in Europe, et cetera. The how of science just really matters.”
</p>
<p class="css-8hvvyd">
And this seems, to me, to be where your exploration really goes. So tell me what you think might have gone wrong in the “how” of science.
</p>
</dd>
<dt class="css-xx7kwh">
patrick collison
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
So I think this point about the sensitivity of scientific outcomes to the specifics of the institutions and the cultures is very important and probably underappreciated. At the beginning of the 20th century, not only was the U.S. not a scientific powerhouse, but it barely had a presence in frontier research, whatsoever.
</p>
<p class="css-8hvvyd">
To become a credible researcher in the U.S. in 1900, you almost certainly had to go and spend time in, most likely, Germany, and failing that, in France or England — you know, what have you. And by 1900, the U.S. was already a pretty prosperous place, and it had a well-educated society, as societies went.
</p>
<p class="css-8hvvyd">
And yet, somehow — and it had universities, right? I mean, Harvard was hundreds of years old by that time. And so it checked many of the ostensible boxes, and yet, the sum total of the U.S. research output as of 1900 was still de minimis.
</p>
<p class="css-8hvvyd">
When James Conant, who was later president of Harvard for 20 years — when he went to Germany as a chemist, which was his original training, in the 1920s, he recounts how dispirited he was by what he found there and how far ahead of Harvard German research was, as of the early 20th century. And then, for a variety of reasons, all sorts of cultural, institutional funding — various transformations happened. And of course, by the latter half of the 20th century, the U.S. was the unquestioned leader at the frontier of scientific progress.
</p>
<p class="css-8hvvyd">
If you look backwards, you see where that locus has been, where the most successful and fertile scientific grounds have been — it has repeatedly moved. As we just said, maybe the 19th century, it was Germany.
</p>
<p class="css-8hvvyd">
Before that, in the 18th century, it was plausibly France. They had a couple of these really successful École Polytechnique and Grande École and so on. And so as a kind of first-order empirical matter, we can just notice, huh, this really seems to matter — and then, the example you just gave of the divergence between Switzerland and Italy.
</p>
<p class="css-8hvvyd">
And so then, if we kind of accept that, and we try to ask ourselves, well, specifically, what are the mechanisms? You know, whats actually going on? Its hard for me to say. It seems like the transmission of research culture by individual researchers matters a great deal.
</p>
<p class="css-8hvvyd">
And you see these kinds of pockets of the cultural transmission repeatedly crop up, where Gerty and Carl Cori — you probably havent heard of — they ran a little biology lab in Missouri, and no fewer than six of their trainees, of students they trained, went on themselves again to win Nobel Prizes.
</p>
<p class="css-8hvvyd">
And if we tell ourselves a standard kind of mechanistic story as to, well, its the funding level, its how much are we investing in science, or its something about whether theres an institution in the courser sense, that can possibly be amenable to it, its very hard to explain these eddies where you see these pockets of excellence really produce these outsized returns. So I think its a complicated question.
</p>
<p class="css-8hvvyd">
I think all of aggregate culture, funding, institutional characteristics, and so on all contribute to it. But if I had to isolate a single variable, it seems to me that the research culture set by specific people and the tacit knowledge transmitted through direct experience is probably the number-one thing.
</p>
</dd>
<dt class="css-xx7kwh">
ezra klein
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
This, I think, is where I sometimes fall into my own pessimism on this. Because I want to believe, as you do, that we can double the rate of scientific advance, maybe even go further than that. But I think the prediction — if Im putting this on institutions, on culture, on pockets of transmission and mentorship — I think the prediction I would make is then, even if you believe, say, that America had a great 20th century, but its institutions have become sclerotic, and weve slowed down, and everything is piled in lawsuits and review boards now, somewhere else that didnt have that, that has a different culture, that has different institutions, would be pulling way ahead.
</p>
<p class="css-8hvvyd">
So you might think, well, China will be pulling way ahead. And youve noted this in some places. Were getting a lot of peer-reviewed research out of China — huge number of citations out of China. Were not seeing them dominate the big breakthrough advances of the era.
</p>
<p class="css-8hvvyd">
It doesnt seem like Europe is lapping us. And so if you think this slowdown is somewhat global, then that seems to me to militate against questions of individual institutions, cultures, how different labs work, because there is so much variation that you should have some of these labs that are doing it right, some of these places that havent piled on a little bit too much bureaucracy. But I dont think we really see that.
</p>
</dd>
<dt class="css-xx7kwh">
patrick collison
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
This diagnosis of these phenomena to cultural, institutional, mentorship-related, interpersonal dynamics, and your observation that its not obviously the case, that there are other places we can pointed that are doing it so much better — for me, my takeaway is that, well, successful cultures are a pretty narrow path. Homo sapiens emerged 200,000 years ago.
</p>
<p class="css-8hvvyd">
And as far as we can tell, for the first 190,000 years of our genesis, we think we were largely biologically equivalent to the people we are today. But as best we can tell, there was some kind of cultural capital that those people lacked for a very extended period of time before human societies in somewhat recognizable modern form started to emerge — agriculture, all the rest.
</p>
<p class="css-8hvvyd">
And in a similar vein, we had many billions of lives and centuries elapsed before the Industrial Revolution., and before we started to put together many of the input ingredients or enough of the input ingredients that we can get sustained improvement in standards of living and ongoing economic growth and progress. And so your point about, well, as I look around, I dont see anything or anywhere thats obviously better, I agree with that.
</p>
<p class="css-8hvvyd">
But again, my takeaway is that thats what makes the question of how do we improve or how can we do somewhat better so urgent and pressing, where its many things have to go right. Its not easy to be even as good as — or to get to a place where things are as good as they are today. What we have is very precious. And I think the threads and the themes that youve been pulling on of late — all of these dynamics underscore their importance.
</p>
</dd>
<dt class="css-xx7kwh">
ezra klein
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
I think thats a good bridge to progress studies as an idea. And I want to have people hold in their heads that idea that progress is very narrow, that it is a very narrow bridge that we have walked on for a very short period of time. But lets try to define it.
</p>
<p class="css-8hvvyd">
When you say progress here, what are you actually talking about? Is it just shorthand for economic growth or G.D.P.? What is progress?
</p>
</dd>
<dt class="css-xx7kwh">
patrick collison
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
Well, I dont know that I would claim to put forth some kind of definitive definition. And I think, to some extent, our intuitions around it are probably broadly correct. And so it might not matter to define it super precisely and finely.
</p>
<p class="css-8hvvyd">
For, me it is something along the lines of our success in realizing a liberal, pluralistic and prosperous society, and a sense among people that their offspring can and probably will do better than they themselves have, and that more broadly, the future will be better than the past, and that were at least making incremental progress towards embodying values and morals that we collectively think we can be proud of.
</p>
<p class="css-8hvvyd">
But I dont think anything that novel in that. I dont think my conception of progress would differ that materially from some kind of average aggregate over any other group of people in the country.
</p>
</dd>
<dt class="css-xx7kwh">
ezra klein
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
I do think theres something interesting, though, which is that if you look at eras that I think progress-studies-type people and economic-growth people and historians of economic growth study most closely, actually, some of the periods where people feel a lot of rapid progress dont fit that at all. You have, say, the Industrial Revolution, where life spans and lifestyle get worse for a lot of the people.
</p>
<p class="css-8hvvyd">
I dont think one will look at that period as unbelievably pluralistic. You have a lot of periods of war when you have very, very, very rapid technological progress, but it happens in context of much more martial societies. So there is an interesting tension, at least in periods — and some of them quite long, actually — where you can have fairly rapid economic progress, but it comes at a cost that I think isnt always acknowledged, but is an important thing to think about.
</p>
</dd>
<dt class="css-xx7kwh">
patrick collison
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
Yeah. So I dont think you could point to some of these periods in the past and say that they definitively embody to the extent that we would fully aspire to some of these broader traits and characteristics. But I think the question is more, what are they doing as — you have to judge it relative to the baseline that preceded them.
</p>
<p class="css-8hvvyd">
And I dont know that the 18th century in the U.K. is some ideal as a society. But if you compare it to the 16th century in the U.K., the ideals and ideas of natural rights and religious tolerance and so on — they were somewhat better embodied by the 18th century than they had just a couple of centuries previously.
</p>
<p class="css-8hvvyd">
And similarly, in the U.S., say, during either war or the 30s or whatever, again, its not like that was any kind of perfect society, but assessed relative to the society of 1830, I think it compares relatively favorably. And I think its not a coincidence that Adam Smith — his first book, of course, was on ethics and morals and trying to instill better general ideals and behaviors across a society.
</p>
<p class="css-8hvvyd">
And maybe after that, he then argued for and laid many of the foundations of what we would recognize as modern economics. So I dont think its perfect. But on average, I think the correlation is positive.
</p>
</dd>
<dt class="css-xx7kwh">
ezra klein
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
So lets talk about the Industrial Revolution for a little bit here. I think a lot of people locate a takeoff in human living standards — it continues to this day — there. And its strange in a way, right? “There” is a very geographically contiguous spot. Its the U.K. — England, actually, I should say, at that point.
</p>
<p class="css-8hvvyd">
And there is a moment in time that probably could have come at another moment in time, depending on how human history plays out in the counterfactual. I know that you have an interest in the theories of why then, why there. How do you work your way through them? What do you think is persuasive for why then, why there?
</p>
</dd>
<dt class="css-xx7kwh">
patrick collison
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
Well, you know, again, I caveat. With all of these topics were discussing through this podcast, maybe the first-order banner for all of them should be, I dont know, these are my best guesses, and I think its important that all of us were pretty humble in the claims and the assertions and the beliefs that we hold.
</p>
<p class="css-8hvvyd">
Recently, Ive been reading a bunch of Irish and Scottish writers around then. Its very interesting, because for both the Irish and the Scots, there was a sort of a pressing and kind of obvious question where England was much more prosperous than they were or we were. And theres no super obvious explanation for that. There wasnt an obvious climatic or natural resource endowment that England benefited from that was lacking in Ireland or Scotland.
</p>
<p class="css-8hvvyd">
It wasnt like England was actually a vastly larger polity. The orders of magnitude were comparable. And Bishop Berkeley wrote this book, “The Querist.” He was asking these questions directly, just like, whats going on? Whats wrong with Ireland? You know, why cant we do this?
</p>
<p class="css-8hvvyd">
And then, you have the Act of Union in 1707, uniting Scotland and England — and sort of similarly, of all these Scottish thinkers being like, all right, were now literally the same country. Why are we so much more impoverished? And then, if you shift to England, theres Joel Mokyr and — youve read his work — and more recently, people like Anton Howes.
</p>
<p class="css-8hvvyd">
And in a similar vein, they go back to — I mean, the word, improvement, came from Francis Bacon, or it was kind of popularized as a concept by Francis Bacon. But thats noteworthy, right? Like, that was not a pervasive broad concept in the 15th century.
</p>
<p class="css-8hvvyd">
I mean, literally, the word, improvement, in this broader societal context, came from word, “translated,” at the beginning of the 17th century. And the ultimate conclusion that these historians and scholars and analysts of the Industrial Revolution come to — and I think its a correct one — is somehow, whether its through Bacon or Newton or various of the tinkerers who produced some of the earliest technological breakthroughs, that somehow, this improving mind-set became pervasive.
</p>
<p class="css-8hvvyd">
You had societies explicitly — like the Hartlib Circle or the Lunar Society, or the Select Society, and the club, and so on — all these societies explicitly devoted to figuring out ways to advance the state of affairs that prevailed. And these societies were comprised of many of the leading people and thinkers and so on of the day.
</p>
<p class="css-8hvvyd">
And it seems maybe a bit satisfyingly squishy to attribute it to something so hard to pin down. But as you run through all the possible other explanations, its differences in IP law. Its difference in the Malthusian conditions. Its difference in the prevalence of coal, you know, et cetera, et cetera. Through various cross-sectional analyses, you can exclude most of these in looking at all of Ireland, Scotland, and England.
</p>
<p class="css-8hvvyd">
It really does seem to me that differences in the mind-set and in the culture are where you have to net out. And thats not to say maybe that its fully sufficient. There might be other preconditions that are important. And then, maybe as a last thing to say, it is striking to me that many of these kind of original 18th-century economic writers and thinkers — and again, the kind of people we look to as the founders of much of the discipline — that they themselves were kind of centrally preoccupied with this.
</p>
<p class="css-8hvvyd">
And yeah, they were in favor of free trade and specialization and human labor and lots of these concepts that were now very familiar with, but they really thought that general mind-set played a big role, too.
</p>
</dd>
<dt class="css-xx7kwh">
ezra klein
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
So lets talk about Joel Mokyr ideas for a minute. So Mokyr is an economic historian. People should read his book, “The Culture of Growth,” which is really fascinating. He argues, as youre saying, that in this period, this mind-set that we can increase the store of usable knowledge, and then use it to alter nature, to better the human condition, takes hold.
</p>
<p class="css-8hvvyd">
Thats a new mind-set. Its different than religious ideas of the past. Its different than cultural ideas of the present. And that, plus a bunch of other things, particularly the republic of letters, the way people are writing letters back and forth, kind of combine into a culture that is able to grow.
</p>
<p class="css-8hvvyd">
But one of the things that I really take from his work, that sits in my head, is he believes its all very contingent. He really believes it might have not happened. But the other is that I think it opens up this question that as a tech person, Im curious to hear your thoughts on, which is, he really believes — Mokyr really believes — that there is a communications infrastructure that arises at that time, that has a kind of culture of generosity and argument and honesty in it, and is built on writing letters slowly to one another, and then copying those letters over to other people.
</p>
<p class="css-8hvvyd">
And that culture is really good for intellectual advancement. I think one of the promises of the internet and the age we live in is, its all faster. We can write to people immediately. Things we write can go viral and be seen by 5 million people all of a sudden.
</p>
<p class="css-8hvvyd">
And that was going to speed up economic growth really, really rapidly. And I would say, you dont see that. So Im curious how you think about communication cultures here and what you think for all the advantages of ours we might not have.
</p>
</dd>
<dt class="css-xx7kwh">
patrick collison
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
I mean, I think its hard to say in aggregate. I feel its pretty likely that the effects are very heterogeneous across different populations. And youve made the case that you think Twitter is bad for journalism and for journalists.
</p>
<p class="css-8hvvyd">
And I guess you live this yourself with your now mostly inactive Twitter account, I guess, apart from announcements. And I think in the case of the internet, that its almost certainly a tremendously large gain that billions of people now have access to educational materials. And some of the otherwise hard-to-communicate tacit knowledge — that things like YouTube videos now made legible and available.
</p>
<p class="css-8hvvyd">
And I think its true that there are various gravity equations that we see across different disciplines. I mean, in economies themselves, in trade, where you rapidly decline in propensities to trade as countries get further from each other — but you have versions of this in academic disciplines as well, where geographic distance correlates inversely with likelihood of the exchange of ideas and so on.
</p>
<p class="css-8hvvyd">
And I think its clearly the case that the sort of reaction surface area has increased substantially by the internet there and represents a kind of efficiency gain for people looking to exchange in ideas. Many of the companies that Stripe works with are remote companies, and they might employ people across myriad countries, and thats a kind of communication and efficiency gain that would certainly not otherwise be achievable.
</p>
<p class="css-8hvvyd">
I think its worth recognizing that the aggregate amount of G.D.P. that we are creating or gaining every year is so much larger now than — I mean, the percentage might be the same. But the total amount of stuff happening, or the increasing amount of stuff happening, is so much larger now than it was 100 or 200 or 300 years ago.
</p>
<p class="css-8hvvyd">
And so for all of those reasons, I think we should give superior communication technologies and faster communication technologies a significant amount of credit, even though the ways in which those are manifests might be hard to measure and somewhat prosaic.
</p>
<p class="css-8hvvyd">
Take my mom, for example. My mom works with a hospital in Minnesota. Our youngest brother has a physical disability. And in the course of that, she trained herself in treatment for cerebral palsy, this condition, and she wrote a book about it, and she did a masters in this. And now, shes trying to improve treatment for this condition throughout Ireland, in the U.S. and other countries as well.
</p>
<p class="css-8hvvyd">
Shes a retired Irish mother who spends some of her year living in the U.S. near her sons, spends the rest of her year living in Ireland, working at a hospital in Minnesota, who just got a proposal to have her book translated into German a couple of days ago. And thats a relatively prosaic story, but literally, millions of these stories exist in kind of aggregate form around the world.
</p>
<p class="css-8hvvyd">
To circle back to the initial thrust of your question, though, I think its at least possible that the internet is bad for civic discourse. Im not saying it is, but its certainly in the realm of plausibility — and that perhaps both things are true, where theres some kind of iceberg where there are these enormous welfare gains that are not that legible, not that visible, lie beneath the surface, and then certain of the most visible manifestations, like what we see on cable news or what we see written in the papers — perhaps that is worse, and perhaps, slightly more structural judiciousness would be desirable there.
</p>
</dd>
<dt class="css-xx7kwh">
ezra klein
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
I want to try to flip that and suggest that — because Im going to push some counter ideas on why we maybe dont see as much progress as we wish we did. But one is that I think possibly, very large welfare losses lie beneath the surface. And beneath the surface of stories like the one you just told about your mother, I think we all have stories of ways or people for whom the internet has unlocked a possibility.
</p>
<p class="css-8hvvyd">
I mean, my whole career is built on the internet. I was an early blogger. I got rejected from my student newspaper. And if there was no blogging, like, god knows what would have happened to me. [LAUGHS] I mean, nothing too terrible, probably, but I wouldnt have the career I have today.
</p>
<p class="css-8hvvyd">
And at the same time, I think that the group of people who, by luck or by temperament, proved very, very good at using the internet, to some degree, distracts from the many, many, many people for whom the internet is fundamentally a distraction machine, or for whom the internet is creating, because of what we built on it. You know, shorter attention spans — how many people would have had an idea, sitting in a room by themselves, or taking a walk, that they never have now, because they never have to have a moment where theyre thinking alone?
</p>
<p class="css-8hvvyd">
And so one thing that I think were all loathe to do is well talk a lot about how its weird that we have so much more knowledge, but productivity isnt increasing faster. Its weird that we have so much more rapid communication between researchers, but science isnt advancing faster. And then, the idea that maybe there are things happening to us that makes us less able to use that increasing stock of knowledge well, or makes us less able to collaborate in a useful way, I think, gets dismissed rather quickly.
</p>
<p class="css-8hvvyd">
But I dont think its totally implausible. Now, I dont want to say, like, the greatest technology we ever had was letter-writing. Obviously, the greatest technology we ever had was blogging in the early aughts when I became a blogger. And whatever happened in your 20s is, like, as good as it was ever going to get.
</p>
<p class="css-8hvvyd">
But I do wonder about these questions. And I think something Mokyr is right to put a lot of attention on is communicative cultures. Communication is how we collaborate. And if communication is in any way getting worse, its going to have pretty big macro effects.
</p>
<p class="css-8hvvyd">
The other thing is if you believe these cultures matter, weirdly, as big as were getting, the internet allows a certain disciplines culture to stretch boundaries and borders in time in a way that it would have been harder. I suspect that labs were more different 50 years ago than they are today.
</p>
<p class="css-8hvvyd">
The countries and the disciplines of researchers and the cultures of researchers in countries or cities are more different from each other 50 years ago than today, which is great if we have the best of all cultures today, but its not that great if you actually think variation is really important.
</p>
</dd>
<dt class="css-xx7kwh">
patrick collison
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
Lets wrap up there. So first, I agree, as a basic matter, that there are welfare losses occurring across society that we should be worried about, and probably everybody listening to this is familiar with the Stephen Pinker case for optimism, and rather than focusing in the headlines, you zoom out, look at these long-term time series. And once one does that, things seem a lot more encouraging, whether you look at it by income or life expectancy or infant mortality or choose your metric.
</p>
<p class="css-8hvvyd">
Something thats been striking to me of late is if you change the x-axis on those time series, and look at many of those phenomena and trends over a much shorter window, the valence changes substantially, and life expectancy in the U.S. is now, in fact, declining. According to C.D.C. data, 54 percent of teenage girls now report persistent feelings of sadness and hopelessness. And you could say, well, teenagers were never stereotyped as the most cheerful lot, but we do have some degree of longitudinal data here, and that number is up from being in the 20s as recently as 2009.
</p>
<p class="css-8hvvyd">
1/2 the population now is either prediabetic or diabetic — again, according to the C.D.C. Basically, point is, when we look at more recent windows, I think there are plenty of aggregate, emergent, complicated outcomes and phenomena that should give us concern. On the degree to which we should attribute the diagnosis to the internet or to our kind of communication media more broadly, its less clear to me in that — not saying its not true, but presumably, the life expectancy one is not — or at least if it is, the mechanism has to be very complicated.
</p>
<p class="css-8hvvyd">
There are a bunch of other health-related ones. So take, for example, say, the incidence of diabetes or pre-diabetes. And you could say, OK, fine, all those things might be true, but theyre totally different. I guess the question I wonder about is, well, we know that lots of basic biological outcomes are correlated with mental states and so on.
</p>
<p class="css-8hvvyd">
And so to what degree is there some more nuanced and complicated relationship there? But I think its a fair question, and I wonder a lot about it myself.
</p>
</dd>
<dt class="css-xx7kwh">
ezra klein
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
Let me ask you about how you think, over the long period here, about the relationship between technology and equity or egalitarianism. And something specific is in my mind. I flicked earlier at the way the Industrial Revolution, for an extended period of time, seems to have reduced a lot of peoples living standards. And it wasnt till later you had changes in redistribution in labor unions and labor protections that the amount of material prosperity that was generating created more broad-based prosperity, particularly at a very high level. I dont know that you can sustain that kind of thing today. We have much more a small-d democratic culture. If things arent working for people, its much easier for them to organize and be heard.
</p>
<p class="css-8hvvyd">
I think theres a much more direct and complicated relationship now between whether or not people feel benefited by technology, and whether or not they are going to accept the conditions and the risks of rapid technological advance. But Im curious, from your vantage point, how you see that both kind of historically and currently.
</p>
</dd>
<dt class="css-xx7kwh">
patrick collison
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
I agree with that. I worry a lot about the basic stability of a society that does not successfully generate and make sufficiently broadly accessible the benefits of economic growth. The world simply has too little prosperity. And if it is not the case that people in the U.S. or people in any country — if they either feel like things arent progressing, or if they feel like maybe somewhere distant from them, things are progressing but they personally will never be able to benefit from it, I think we put ourselves in a very dangerous and likely unstable equilibrium.
</p>
<p class="css-8hvvyd">
And if you go back to — well, you dont have to go back very far in history to see, obviously, plenty of instances where this kind of instability brought the whole house of cards down. And so as a consequence of that, I worry a lot about, how do we simply make sure that — or one of the small things we each individually can do to try to make sure that society is generating enough economic gain and enough broadly experienced welfare gain that the whole compact can be maintained?
</p>
<p class="css-8hvvyd">
And again, I dont think theres a ready neat kind of singular answer to that. Maybe Stripe as part of our small little contribution in one little fissure. But I think the central question youre getting at is super important.
</p>
</dd>
<dt class="css-xx7kwh">
ezra klein
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
And one of the questions I wonder about there — weve talked about the way progress has been very geographically lumpy, lets call it, right? Theres a lot that happens in very small places, and it ends up affecting the whole world. Obviously, then, the gains of progress sometimes have that quality, too.
</p>
<p class="css-8hvvyd">
And I do think of one of the politically destabilizing effects of the past, lets call it, 30 or 40 years of digital progress, is being the concentrations of wealth. We just used to have a lot more spread. Even putting the questions of rising inequality aside, just where rich people were was different.
</p>
<p class="css-8hvvyd">
And so where they were giving a lot of money to the local hospital was more spread out, say, across the country or in other countries across the land. But here, even as the internet is supposed to democratize distance, and in many ways, has — I mean, telework is not a fake phenomenon. It has really concentrated the wealth of that to, literally, where were sitting, but to New York. Theres a lot of money now in Austin.
</p>
<p class="css-8hvvyd">
And then, on top of that, you often have barriers of entry, in terms of how many homes can be bought. So its not even like people can move to the place where all the economic opportunity is happening. And I do think that creates some of the skepticism you see of technology.
</p>
<p class="css-8hvvyd">
I dont think a lot of peoples — I think people are really excited about a lot of the goods theyve gotten from it. But in this kind of macro political sense, as youre saying, in a period of a lot of change, a lot of folks with real backing in the data dont feel life has gotten better at the macro level.
</p>
<p class="css-8hvvyd">
Life expectancy, happiness, political stability — its not like you can look around and say, well, I got this computer in my pocket, and everything else is going great, too. Its like, I got this computer in my pocket, and what it keeps telling me is that everything is going to hell. Now, maybe its telling me that a little bit too much, but there is validity to the narrative.
</p>
</dd>
<dt class="css-xx7kwh">
patrick collison
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
Yeah. So again, vehement in agreement on the sort of central importance of making sure that improvements in the standard of living are actually broadly realized across the society. That, too, I think, could serve as a manifesto for some of these Progress Studies ideas.
</p>
<p class="css-8hvvyd">
On the internet in particular, or on technology and the technology sector and so forth, I think its complicated and difficult to try to sort of fully collapse or linearize it or something, where on the one hand, you have some of these concentration dynamics you identify. At the same time, of course, it is also a tremendous and incredible dispersal agent in making some of those possibilities and opportunities be more broadly available.
</p>
<p class="css-8hvvyd">
I think its dangerous to take an excessively U.S.-centric perspective here. If you interact with or look at survey data, or otherwise try to assess whats the sentiment of people in Poland, whats the sentiment of people in India, or whats the sentiment of people in Indonesia, they view the internet extremely positively. And I think correctly so, where their opportunities for advancement would be substantially curtailed in the absence of much of what the internet makes possible.
</p>
<p class="css-8hvvyd">
I think in places like the U.S., or actually, even at home in Ireland, some of this story is complicated by lots of other things, but including — and I think, substantially — dynamics around housing policy, where theres an extensive literature showing that, for example, a very substantial moderating effect on the increase in wealth inequality that would otherwise have happened, or income inequality, was geographic reallocation and people responding rationally to, OK, things in New York are going great, or things in California are going great.
</p>
<p class="css-8hvvyd">
And if you look at the rate of increase of the Californian population, say, through the 1960s, that was a tremendously potent mechanism for us redistributing some of the economic gains that were being realized at the time. And of course, now, we have this crazy position, where California is losing population at the same time where the market caps of these companies and the profits of these companies are increasing very rapidly.
</p>
<p class="css-8hvvyd">
But as one assesses that dynamic and tries to ask the question of, well, why arent these gains being better or more broadly distributed, its certainly not clear to me that the answer even lies in the realm of technology qua technology. And I think its certainly more broadly, again, some of these considerations like geographic allocation.
</p>
</dd>
<dt class="css-xx7kwh">
ezra klein
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
Let me ask one more question on the geographic dimension, and then Ill move on to it. And its on my mind, in part because when I try to think about progress, when I try to think about what inventions and innovations are coming really quickly, I actually see a bunch here. And Ill use A.I. as an example.
</p>
<p class="css-8hvvyd">
Ive met people who are trying to automate a bunch of legal contracts. It makes a ton of sense. People pay a lot all over the country — to some degree, all over the world — to get fairly basic legal contracts drawn up — wills and real estate documents and merger agreements and all kinds of — from the small to the large.
</p>
<p class="css-8hvvyd">
If you imagine that getting really effectively automated, though —
</p>
<p class="css-8hvvyd">
you think about Saint Louis, Missouri, where some of the people who are important pillars of the community work in law firms there, and what they do is contracts. They do estate planning and all the things that people have to do in contracts. And if it actually does get concentrated to really, really great contracting firms in the Bay Area or in New York, on the one hand, the democratizing potential will really be realized. Those contracts will get cheaper.
</p>
<p class="css-8hvvyd">
Theres also a theory in crypto of smart contracts. And on the other hand, you really will have a lot of that — the gains of that, economically, going to smaller areas and aggregated across a bunch of different domains. So graphic design, in all kinds of areas of the country — midlevel graphic designers get paid to make logos for local businesses.
</p>
<p class="css-8hvvyd">
Its pretty clear theyre going to be able to do that really, really easily on things like DALL-E pretty fast. So you can imagine a lot of that area getting wiped out. And you kind of run through a couple of these. And before you get to really unbelievable and sci-fi-like dimensions of artificial intelligence, you just have a thing that is going to democratize a lot of capabilities in a way thats going to put the money for those capabilities both a little bit back into the pockets of the people who need them, and then a lot into the people who run the best A.I. rigs and is going to have a really weird geographically destabilizing effect.
</p>
<p class="css-8hvvyd">
And that paradox of the internet both democratizing geography, and then concentrating wealth and capital in very small areas is, to me, a central challenge. Because if you get that wrong, if it goes too much in the concentration area, I think were going to lose a lot of the political stability we need here. But youre more on top of these technological advances than I am. Do you think the trends there are going to play out differently than Im worried they will?
</p>
</dd>
<dt class="css-xx7kwh">
patrick collison
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
First, yeah, its not — I dont think its foreordained whether or not these are going to be centralized technologies. I dont know. And on the one hand, theres, I think, an obvious feature we can contemplate, where there are only three A.I. models, and they are rooted in the hegemons, the citadels of Silicon Valley technology, and we all are digital serfs who are subsistence-farming on their gains.
</p>
<p class="css-8hvvyd">
I think theres also a very plausible story where these technologies prove substantially less defensible than we might have expected, and where, instead, they have this enormously decentralizing effect. Because otherwise, economies of scale that only large firms could benefit from can now be realized and pursued, even by massively smaller firms. And if we look at the recent history of A.I. — I dont think any clear story there, but it does feel to me that it has been more biased towards the second story than the first.
</p>
<p class="css-8hvvyd">
There are now multiple companies with large language models. There are a number of very successful open-source A.I. efforts. Actually, there was a really cool example from Replit, which is a service — its a programming I.D. in the browser, used by kids learning to code, but also increasingly used by people who are pursuing serious programming.
</p>
<p class="css-8hvvyd">
And they recently released a GitHub copilot-like technology, where it will kind of autocomplete your code in the editor, and where you can do some pretty cool things. Like, you can highlight a block of code and ask it to be explained, and itll turn code into natural language, into English, and say, hey, heres what this code is doing.
</p>
<p class="css-8hvvyd">
Anyway, they wrote a blog post about how they built this, and they describe how it was built by one guy over the course of a couple of weeks. And maybe thats only the case in the early days of this AI technology. I mean, in early computer games, the first games were built by a single heroic person, and now, its these gigantic studios and enormous CapEx budgets.
</p>
<p class="css-8hvvyd">
And so I think the fact that this is the case today doesnt mean that it will remain the case through time. But my takeaway is that at least not foreordained that AI or any of these other technologies will be centralizing forces. And then, the other thing to observe is that when we talk about these being centralizing, I think theres a question as to, do we look at it in relative or absolute terms?
</p>
<p class="css-8hvvyd">
And my contention would be that, both from a moral standpoint, but maybe more importantly from kind of a political-economy standpoint, what will matter is whether, on an absolute basis, people feel like they are realizing opportunities, their lives are improving, that things are getting better, that their kids will be in a better situation and so forth. And exactly how much value is realized by the companies themselves doesnt actually matter that much, compared to that former question.
</p>
<p class="css-8hvvyd">
And whether A.W.S. or whether any of these organizations has super high or super low profit margins, I dont know is nearly as important as what is the actual effect on these communities and individuals across the society. And so in as much as one means — by centralizing, one means a large share of the profits, I think it is probably a more useful framing to look at it instead in terms of absolutes, and in particular, the absolute surplus generated by the users.
</p>
<p class="css-8hvvyd">
[MUSIC PLAYING]
</p>
</dd>
<dt class="css-xx7kwh">
ezra klein
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
What have you come to believe about the relationship between progress and war?
</p>
</dd>
<dt class="css-xx7kwh">
patrick collison
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
I am somewhat skeptical that war is as conducive to breakthroughs as we might intuitively conclude, or as is sometimes claimed. Youre probably familiar with Alexander Fields work on the 30s here. And his basic claim is, the productivity gains we often attribute to the Second World War in the U.S. — like, those foundations actually were laid in the 30s, and then the first half of the 40s were a period of decreasing productivity as we massively, inefficiently reallocated our economic resources for the purposes of winning the war, which was probably a good thing to do, but inefficient in narrow economic terms.
</p>
<p class="css-8hvvyd">
And he has a new book coming out, I think, next month, that sort of extends this argument into the 50s.
</p>
<p class="css-8hvvyd">
And as one takes stock of the scientific breakthroughs — and so Stripe Press recently republished Vannevar Bushs memoir, where he takes stock of this.
</p>
<p class="css-8hvvyd">
And obviously, you have, say, the Manhattan Project, and thats a big deal, certainly. But it doesnt feel to me that had the Manhattan Project not occurred, that peaceful development of nuclear technology would have been massively stymied. Maybe it would have taken another 10 years, but it was already happening to some meaningful extent.
</p>
<p class="css-8hvvyd">
And then, as you take stock of all the other breakthroughs that took place in the U.S. during the Second World War, there were some meaningful stuff like blood plasma and blood transfusions. There was some significant breakthroughs there. Some of the first antimalarial medications, radar, the proximity fuse, which Im not sure is all that useful outside of military applications.
</p>
<p class="css-8hvvyd">
But by the time you get down to invention 6 on the list, I dont know that as you compare that list to, again, some counterfactual of what would otherwise have ensued, that it looks radically better as you take stock of the Cold War and the enormous fraction of our economic resources and human capital that were devoted towards us, that the gains necessarily look that impressive. And so again, its super hard to judge. You dont have proper controls and so on. But Im skeptical.
</p>
</dd>
<dt class="css-xx7kwh">
ezra klein
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
Let me take the other side. So theres a question of, during war, how much did we invent during World War II. And thats a question of how much the threat of war or the competition with an adversary ends up charging up innovation and convinces us to put resources, both in terms of people and in terms of money, and maybe in terms of institutions, into projects we wouldnt otherwise have done. I think theres an argument, at least, that we went to the moon because of the Soviet Union. It would not have done that for some time. Probably would have eventually done it, but also, who knows?
</p>
<p class="css-8hvvyd">
As Derek Thompson, who Im working on a lot of these ideas with, likes to point out, the Apollo Project was unpopular. It was not something that commanded wide popular support.
</p>
<p class="css-8hvvyd">
Even now, if you look at the CHIPS Act that passed, it passed, with all that spending on semiconductor research and other kinds of next-generation technologies, under the framework of, lets compete more effectively with China. If you look at all the things Darpa has done or been part of, the fact that “defense” is the first word in the Darpa acronym, I think, is meaningful.
</p>
<p class="css-8hvvyd">
Theres something about what threat persuades societies to do, and persuades them to do technologically or what risks it allows otherwise-more-cautious governments to take, or what failures they could justify that allows them to have big successes. Something there doesnt seem to small to me.
</p>
<p class="css-8hvvyd">
And maybe its my political side, where I so often see scientific funding justified in Congress in terms of countries were competing with or are adversaries with. And I see what the defense industry can do that other institutions cannot, because they dont get a lot of political blowback. But I dont know.
</p>
<p class="css-8hvvyd">
I worry a little bit about how much we seem to need the threat of another to accelerate things. And in a small way, maybe, we see what the pandemic — where we were willing to move much, much quicker on things like mRNA technology than I think we would have outside of it.
</p>
</dd>
<dt class="css-xx7kwh">
patrick collison
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
Yeah. So I think its certainly true that the crisis can cause the discontinuous shifts that have large effects, which in your example, say, are probably super beneficial. I dont know. If you take Darpa as an example, it started as Arpa, as a more open-ended research institution and set of programs, and then with the Vietnam War, had the D pretended to it.
</p>
<p class="css-8hvvyd">
And we decided, in the face of threat, to make it more applied, to take more seriously its translational and kind of, quote unquote, “competition-oriented mandate.” And I think that was bad for Darpa. And the internet, which arose under Arpa — its hard to think of innovations of similar magnitudes that then occurred in then-Darpas subsequent, say, two decades.
</p>
<p class="css-8hvvyd">
If you take, say, U.S. science in general, the war — the Second World War — to some extent, the first, but much more so the second — precipitated an enormous centralization of U.S. science in its aftermath. Because we really marshaled together all of the — or a significant fraction of the scientific capacity of the U.S. in service of the war effort.
</p>
<p class="css-8hvvyd">
For, example the 50 percent overhead, the fraction of government grants that goes to universities — that was chosen in the early days of the coordination of the war effort, and has now become a kind of a pillar of academic and research funding in the U.S. And in the aftermath of the war, we sort have this question of OK, weve kind of pulled everything together. Now, what do we do?
</p>
<p class="css-8hvvyd">
And that became, in various ways, the N.I.H. and the N.S.F. and so on. I mean, the N.I.H. predated it, but the growth of the N.I.H. really occurred after the war. And the federal government, shortly thereafter, for the first time, became the majority funder of US science. And all that centralization — and I mean, you pointed out the benefits of variety and of experimentation and of heterogeneity, and having some degree of institutional and structural diversity and so on, I totally agree with all of that.
</p>
<p class="css-8hvvyd">
And I think all of that was very meaningfully curtailed by, again, the aftershocks of some of the threats that we faced during the war. And if you think about the things that were maybe happiest about having happened — the founding of the major new U.S. research universities in the latter parts of the 19th century or the revolution in health care and kind of medical practice that first happened at Johns Hopkins, and then kind of codified in the Flexner Report, or the great industrial research labs of Bell and Park and so on — or excuse me — Xerox — they didnt obviously come from a place of fear or a threat.
</p>
<p class="css-8hvvyd">
They came from a place of hope and optimism and opportunity. And maybe there are some inventions that youre more likely to get to from some of these external pressures. But yeah, if you gave me a dial, and I can kind of turn up or down the threat or fear index of society, its not super obvious to me that one would want to turn it up if what one cared about was the aggregate rate of progress.
</p>
</dd>
<dt class="css-xx7kwh">
ezra klein
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
Thats a good bridge, I think, to the question of institutions. And I take one of the main concerns of yours, of progress studies, as being around institutional slowdown. You have this idea that we dont meta-maintain institutions very well.
</p>
<p class="css-8hvvyd">
They start in one place, and then over time, they crust over, and we dont really know what to do with that. Give me a little bit of your thinking there.
</p>
</dd>
<dt class="css-xx7kwh">
patrick collison
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
I think institutions, the cultures they instill and act as kind of coordination points and training sites for — those of enormous consequence — I think much of the success of the U.S. and of various other Western countries has, in substantial part, been attributable to successful institutions. Most people would accept, I think, that there is, to some extent, consistent trends that tend to happen with institutions through time.
</p>
<p class="css-8hvvyd">
Just maybe most basically, the problem that gives rise to an institution in the first place is probably a pretty real and significant problem. No one would have taken the time to found the institution if it wasnt. And there can be some degree of drift there, where we dont necessarily decommission the institution once the problem has subsided or abated.
</p>
<p class="css-8hvvyd">
And then, you tend to attract a certain kind of person in the early days of an institution — people who are slightly less status and reputation and procedure-oriented, because a new institution almost never has that. And then, through time, the sort of collective or the mission-oriented incentives of the institution can kind of drift somewhat from the individual incentives that particular people are subject to.
</p>
<p class="css-8hvvyd">
I think all this stuff exists. And the thing that I observe, or that I just find myself thinking about is, weve had eras of institution formation in the U.S. It has not been kind of a constant rate through time. And the New Deal maybe, and say, the 30 years afterwards, and the Great Society — we bookend it with those start and endpoints.
</p>
<p class="css-8hvvyd">
That was a period of tremendously active institution construction and formation in the U.S., Darpa being — or Arpa originally being a good example, and indeed, NASA. And I guess I find myself wondering, one, if we didnt have any of these institutions — and Im not saying we should get rid of them. But if we didnt have them, what institutions would we found today, first, and how high in the list would NASA be, for example?
</p>
<p class="css-8hvvyd">
And then, secondly, in as much as we accept that some of these institutional dynamics exist, like the fact that sclerosis as an emergent property arises, what do we do about that? And lots of people have told us its pretty — doesnt need a lot of teasing apart to see it as one compares NASA and SpaceX and the respective budgets, and the respective achievements, and so forth, I think its hard to not at least wonder about their respective efficiencies.
</p>
<p class="css-8hvvyd">
And say, if society could only have SpaceX or NASA, which one would we choose, and what should we conclude from that, and to what extent do those phenomena generalize elsewhere? I dont have answers to these questions. But I find that in the political discourse — not that anybody is celebrating that, but in the discourse, its very easy to get, I think, very wrapped up in questions of optimal funding levels, and should this number be 10 percent or 50 percent or higher or whatever, whereas to me, a lot of our satisfaction with the outcomes seems to hinge on deeper questions about the nature of the institution.
</p>
<p class="css-8hvvyd">
I dont know that the problem or benefit, or anything good or bad about NASA is attributable to the budget, per se. It seems more, kind of, resonant in some of these deeper cultural questions. And then, in the recent pandemic, or in the — I dont know. I was going to say, ongoing pandemic. But I guess as of two days ago, with the Presidents verdict, it is now over.
</p>
</dd>
<dt class="css-xx7kwh">
ezra klein
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
Its over. Congratulations, everybody.
</p>
</dd>
<dt class="css-xx7kwh">
patrick collison
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
Exactly. But anyway, I think that was maybe a vivid demonstration of many of these dynamics, where I dont know this any of the story about the institutional response to the pandemic should be primarily one of funding. I think its much more about the dispositions and the attitudes and the cultural biases of entities like the N.I.H. and the F.D.A. and the C.D.C.
</p>
</dd>
<dt class="css-xx7kwh">
ezra klein
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
I find the NASA SpaceX example an interesting and provocative one. Because on the one hand, I think what youre saying is completely true. And where a lot of the NASA programs and projects have gone in recent decades, is just — its sad. Its just a sad story.
</p>
<p class="css-8hvvyd">
And on the other hand, the idea that you — the thought experiment of choosing between NASA and SpaceX — the thing that it immediately asks is, well, you cant. Because without NASA, there is no SpaceX. And one way the private sector handles a lot of these questions — I mean, Im always struck by how much of the way biotech research works is that big pharmaceutical companies acquire small biotech firms that have made a breakthrough or have come up with a very promising candidate. This is kind of an accepted thing that the big companies — they do a fair amount of research, but a major, major innovation transmission there is small groups do more, quicker, and theyre just going to buy them. And the NASA SpaceX example has a little bit of that dynamic to it, although with a different mechanism of financing. And I dont know. I wonder if there arent deeper lessons there.
</p>
</dd>
<dt class="css-xx7kwh">
patrick collison
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
Yeah, I dont mean here in the NASA example — like, I dont think reducing it to a simple binary of this-or-that is correct. Its more, what should we make of the differences in these two organizations? And given those observations or beliefs, what do we then think an efficient outcome might look like?
</p>
<p class="css-8hvvyd">
And do we think that where we are today — this prevailing status quo — is optimal? Or are there other things we can do better? And maybe an important thing to say within all of this is, to the extent that these are all kind of inevitably determined outcomes, maybe it doesnt really matter if we think things would be better or worse. Were going to end up in the same place, regardless. But I think for all of these, its super contingent. And various aspects of both funding decisions and, kind of, the precepts and methodologies of the N.I.H., how we design I.P. law, how we regulate and require and run clinical trials — there are tons of individual contingent decisions that we kind of have collectively made that give rise to the biotech and to the pharma ecosystem.
</p>
<p class="css-8hvvyd">
And certainly, in the case of space, you know, like, it doesnt have to be this way other. Universes, no pun intended, are possible. I think perhaps the thing that people underappreciated with science in the U.S. is, it has been very different in the not-too-distant past.
</p>
<p class="css-8hvvyd">
Peer review is a relatively recent invention. Modern journals are a relatively recent invention. As I mentioned, the federal government being the primary funder of basic research is a relatively recent invention.
</p>
<p class="css-8hvvyd">
And molecular biology was, in significant part, a thesis by Warren Weaver at the Rockefeller Foundation. Theres a thing here, and we should aggressively pursue it. But importantly, it was not — it required an institution, an organization, that was not part of the standard apparatus, for want of a better term.
</p>
<p class="css-8hvvyd">
And the Broad Institute, over the last 25 years, has been enormously successful in the field of genomics and functional genomics and CRISPR, et cetera. And the Broad Institute is itself a kind of structural innovation, breaking somewhat from the more traditional prevailing university model. And so I think the fact that so many of our successes are associated with some degree of structural and institutional change should be somewhat thought-provoking for us.
</p>
</dd>
<dt class="css-xx7kwh">
ezra klein
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
Youve been trying to work in the space of institution-building here, too. I want to talk about Fast Grants and about Arc a little bit. So lets begin with Fast Grants. What is it, and what has it taught you?
</p>
</dd>
<dt class="css-xx7kwh">
patrick collison
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
Well, its mostly “what was it.” In the early days of the pandemic — well, I should preface all of this by saying — well, Ill reaffirm my preface that I dont know, to every question. But more importantly here, I will say, my now-wife is herself a scientist. Weve known each other since we were teenagers. We spend a lot of time talking about science in various forms.
</p>
</dd>
<dt class="css-xx7kwh">
ezra klein
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
You met — am I allowed to say this? You met at a science competition.
</p>
</dd>
<dt class="css-xx7kwh">
patrick collison
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
That is true. We met at a science competition, 100 teenagers, and —
</p>
</dd>
<dt class="css-xx7kwh">
ezra klein
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
And she beat you.
</p>
</dd>
<dt class="css-xx7kwh">
patrick collison
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
And yes. I was the runner-up, and she was the winner. I had created a programming language and a new dialect of lisp, and she had created a new treatment for urinary tract infections. And so I really dont envy the judges for having to figure out what framework one should use to make all these comparisons and lots of other people.
</p>
</dd>
<dt class="css-xx7kwh">
ezra klein
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
You sound a little bitter, man.
</p>
</dd>
<dt class="css-xx7kwh">
patrick collison
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
[CHUCKLES] I was gonna say, but no, we can all agree this the correct outcomes ensued. Anyway, so we were living together in March of 2020, holed up. And a number of her friends and colleagues were unsurprisingly with, I guess, a large fraction of all biology scientists, were trying to urgently repurpose their work to figure out, well, could they do something that would be somehow benefit to accelerating the end of the pandemic?
</p>
<p class="css-8hvvyd">
And by early April, so a couple of weeks into lockdown, when it was becoming apparent and striking to us, which was it is difficult for these people to get funding for their work. And that might sound a bit, kind of, surprising, because you think, well, dont they have some degree of money already? And couldnt they just go and just spend that?
</p>
<p class="css-8hvvyd">
But there are, obviously, significant rules around and restrictions around that which one can do with ones grant money. This is money provided by the government for a purpose. And so its not like you can go and readily spend it on something totally unrelated.
</p>
<p class="css-8hvvyd">
And the money is administered by the university, and so you have to go through their proper procurement processes. Point is, lots of restrictions on scientists pecuniary ability to suddenly repurpose the research agendas. And we kind of thought, well — we assume maybe in the early weeks, that presumably various bodies — I dont know who — some kind of amorphous other, some combination of C.D.C., F.D.A., N.I.H., philanthropies — whatever.
</p>
<p class="css-8hvvyd">
Somebody will come along and just give these scientists the obvious money that society clearly should, so they can go, and they can pursue these programs. Didnt seem to be happening. I mean, to be fair, I dont want to give us too much credit. Various people were doing things right off the bat in various different places, but we just personally knew of lots of specific examples of really good scientists who were unable to make progress of their work to the extent that they would like. So we tried to set up what we thought would be a pretty small initiative, and called Fast Grants.
</p>
<p class="css-8hvvyd">
The basic idea would be, you send us some kind of proposal. And initially, within 48 hours, you would get a funding decision and either receive money or not. We started out with a pretty small amount of money.
</p>
<p class="css-8hvvyd">
The initial donors — we were among them, but there were a number — contributed, best I recall, about $10 million. Launched the website early April 2020. Quickly inundated with, I think, four and a half thousand applications, which, given our promised 48-hour turnaround, was somewhat challenging.
</p>
<p class="css-8hvvyd">
I should say this was myself. This was Silvana, my wife, and this was Tyler Cohen. So we had an immediate question as to, how do we actually run a philanthropic endeavor? And how do we stand it up in very short order? And he, through Mercatus and through Emergent Ventures, had some experience of very efficient and somewhat-scaled grant-giving. And so the three of us worked together to put it together over the course of a week or so. We proceeded over the course of, roughly speaking, the next year, slightly more, to make about 200 grants, eventually dispersing almost — or slightly over, actually — $50 million in total, to universities around the world, though primarily in the U.S.
</p>
<p class="css-8hvvyd">
And you ask, kind of, what did we learn? A big surprise was how slowly other parts of the establishment mobilized. And various of the projects we funded or the labs we funded and so on — theyve gone on to now do — none of them were directly implicated in the vaccine research project that ended up yielding so much fruit. So again, I dont want to give Fast Grants too much credit. Eventually, the thing that really mattered, we had nothing to do with. But versus the projects, things like Saliva Direct, which was in the summer an early discovery that saliva tests work basically as well as the nasopharyngeal swabs we were all being subject to, or various discoveries around possible therapeutics, some of which are — still continue to go through clinical trials, and may still turn out to matter to a significant extent. And that 500 people are still dying in the U.S. per day from Covid, and — despite the existence of the vaccines and so on.
</p>
<p class="css-8hvvyd">
So anyway, various discoveries ensued that I think will prove to be important. And the second thing we learned, which is not really related to Covid or the pandemic, but has certainly been significant for us, is — it just got us thinking more deeply and broadly about the questions of, how do scientists choose what to do? And what are the constraints theyre subject to as a practical and applied matter?
</p>
<p class="css-8hvvyd">
And this gets back to all this discussion about both culture and institutions. And towards the end of Fast grants, we ran a survey of the grant recipients. And these are essentially all people who dont normally — certainly dont normally work on Covid. Covid didnt exist. But they dont even normally work on viruses, for the most part. These are basically kind of broadly drawn as a cross section across biology. And we just asked them, as a general matter in your regular research, if you could spend your grant money however you want, how much would you change your research agenda? So not an increase in the funding level, which tends to be what we discuss in as much as were discussing science policy across society. But much more specifically and narrowly, if you had complete autonomy in how you spend whatever grant money youre getting, how much of your research agenda would change? And our intuition was that maybe a third of people would like to be doing something meaningfully different to what they actually are.
</p>
<p class="css-8hvvyd">
But of these scientists, and these are really good scientists, four out of five told us that they would change their research agendas, quote, “a lot.” We gave them three options. Not much, or not at all, a little, and then a lot. Four out of five chose the maximum option on our survey. So I just find this incredibly thought-provoking.
</p>
<p class="css-8hvvyd">
Basically, we seem to be in a situation where most of our top scientists arent doing what they think would be best for them to do. And we could say, no, our various committees and governing bodies and decision-making apparatus and so on, they know better. And Im not saying it would be completely unreasonable for one to maintain that. But that would seem to be a very central question about the construction of our scientific apparatus. And I think that should give us some pause.
</p>
</dd>
<dt class="css-xx7kwh">
ezra klein
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
There are a couple things there. One is that it is a consistent observation I have learning about new areas that there is a way were taught the thing works, or people think the thing works, and theres this huge middle layer. Right? So in politics, which I know very well, and legislation, you have the “Schoolhouse Rock” version of how a bill becomes a law. And then its, like, a filibuster is how a bill becomes a law or does not become a law.
</p>
<p class="css-8hvvyd">
We were talking about drug innovation earlier. I think the folk way people think it works is we make a discovery about a drug, and then, like, we make a drug out of it after some tests. But you talk to people who work on pharmaceuticals and just clinical trials.
</p>
<p class="css-8hvvyd">
And in science — I think if you had asked me as a high schooler, had some science classes, Id have told you something about the scientific method. And then you talk to a scientist, and its grants. Like, grants are how science works. Grants are the middle layer between — you are a scientist, and you can do some science. And grants are how the N.S.F. and the N.I.H. work. Theyre how a lot of the universities work. Theres fund-raising. I mean, there are different ways that it happens. To make the question of “Are we doing science well?” a little bit more precise, I think one version of that question is, “Are we doing grants well?” And I think that question is more tractable. People dont feel as defensive about it.
</p>
<p class="css-8hvvyd">
But Ive talked to a lot of scientists in the course of my work. Ive covered health care for my entire career. And I dont know any who think were doing grants well. I dont know any who will not complain to you for hours.
</p>
<p class="css-8hvvyd">
And they may be wrong. And I do want to note — because they also just have somewhat different incentives. I mean, I was noting earlier, and I think its very real. The government, particularly when it gives out grants, needs to worry about the reputational cost of the grant. If the grant goes wrong, if not enough of the grants pay out into useful research. If Rand Paul can stand up in Senate and make what you did sounds silly, these things really end up mattering. And so you get a process that is optimizing for a lot of different things.
</p>
<p class="css-8hvvyd">
But the question of whether or not we do grants well ends up being really, really, really important in every country that does major capital science that I know of, and is just not the main question for a bunch of different reasons we ask.
</p>
</dd>
<dt class="css-xx7kwh">
patrick collison
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
Yeah. Another question we asked in our survey was how much time they spend on the grants. I think to some extent, this is perhaps — at least, of those whove spent some amount of time interacting with scientists, kind of more broadly known than perhaps the finding with respect to how they do — or the degree to which they can choose what they work on. But we found that — or they reported to us that they spend on the order of 40 percent of their time on grant administration.
</p>
<p class="css-8hvvyd">
And even if one were to maintain that the decision-making apparatus around what scientists do is somehow efficient, I think it is a very tenuous position to also try to argue that 40 percent of the best scientists time is optimally allocated towards grant applications, authorship and administration. And were not talking about an inconsequential 40 percent here.
</p>
<p class="css-8hvvyd">
I mean, this is 40 percent of the time of this super-elite 10,000, 100,000, whatever it is, some relatively finite number of people. And weve chosen to take and to redeploy almost half of their time in service of technocratic, bureaucratic undertaking. And getting back again to this point about people perhaps falsely assuming that things have been more inter-temporally consistent than they have, that percentage has increased very substantially over the last couple of decades as the overall edifice of science has grown, and as the kind of acceptance rates and the various thresholds for various grants has become more exacting.
</p>
</dd>
<dt class="css-xx7kwh">
ezra klein
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
How we allocate peoples time is really important. But also, just how we allocate talent is really important. And it brings me to something you said that I wanted to ask you about. This was in response to a question about whether big tech companies are hogging all the talent in society.
</p>
<p class="css-8hvvyd">
And you said, quote, “I dont think that the ambitious upstarts who go into high speed rail in America, anyway, are going to have a great time or have much success in convincing their friends to follow them. And I suspect that for various reasons, too many domains look somewhat like high speed rail.” And so you go on to say that theres a view that the internet is a frontier of last resort, and that you dont think thats totally wrong.
</p>
<p class="css-8hvvyd">
So tell me about that. Tell me about the idea of the internet as a frontier of last resort. But behind that, this idea that other frontiers where talented people might want to go and make their mark on society have closed.
</p>
</dd>
<dt class="css-xx7kwh">
patrick collison
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
Youre familiar with and youve probably written about the Stephen Teles idea of kludgeocracy. And I kind of like the term “kludgeocracy,” because rather than making some of the inhibitions that people might encounter in pursuing something like high speed rail, rather than casting those as being deliberate, the valence is more that its this kind of emergent, inadvertent and kind of complicated phenomena that nobody perhaps particularly wants or chose.
</p>
<p class="css-8hvvyd">
And I think the case of Californias high speed rail is quite striking, where — youve written about this and kind of similar projects and the New York subway expansion and so on. And congestion pricing and so on. But its striking where its not actually obviously a question of first order political will. Like, were willing to fund the high speed rail in California. Were clearly willing to invest in building the subway expansion in New York. But somehow, somewhere between that first order decision and desire and our actual ability to kind of instantiate it, something really goes wrong.
</p>
<p class="css-8hvvyd">
And you contrast that with stories of — in the case of, say, California, Henry Kaiser and these various other early part of the 20th century operators in the physical realm. And for a variety of reasons, but mostly prosaic state and county-level complications and things that would extend the time horizon of ones project, it has simply become meaningfully less-appealing for those people to undertake these initiatives. I mean, Foster City, not too far from where we are now, thats named after the eponymous Mr. Foster.
</p>
<p class="css-8hvvyd">
He was a developer. He decided, well, with reclaimed wetlands, Im going to build a city. California is growing quickly. The Bay Area is a — kind of propitious and will be a long-term successful area. And I think this place simply needs more housing.
</p>
<p class="css-8hvvyd">
And he, with that kind of founder energy, was able to give birth and rise to the city that now bears his name. I havent met anybody pitching me on a similar city on the shores of the Bay in the last couple of years. But I would imagine that were one to adopt that ambition today and to propose that maybe the San Jose Marsh wetlands should themselves be an expansion of San Jose, I dont think one would get very far.
</p>
<p class="css-8hvvyd">
And in fact, even for much more sort of limited things, like additional runways or runway expansions at S.F.O., even they have now been stymied for decades at this point. That ability to translate that into something enunciated has dissipated and deteriorated. And then I think the kind of individual version is, and if I want to be that heroic solar farm entrepreneur or railway magnate, that my practical ability to do so has been meaningfully curtailed.
</p>
</dd>
<dt class="css-xx7kwh">
ezra klein
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
Yeah. I mean, thats what Im getting at here a little bit, which is talent really matters for a society. Where the most talented people go really matters for society. And a lot of those people want to go somewhere where they can have a really big effect. I think theres been a huge rush to digital land because you can build on digital land. You can build quickly. I mean, its interesting to some of the dynamics were talking about, the temporal dynamics were talking about, that you see this dynamic even within the tech world.
</p>
<p class="css-8hvvyd">
There was a while where it was really exciting to go join Facebook, go join Google, go join one of the big companies. Because you could do so much. And thats still, to some degree, true. But they got really big. And so crypto got — whatever you think of crypto, one thing that is exciting about it to people is the idea that its open land. That you can go in there and have a really big effect on it. Build something new just with a couple of friends that might change the whole direction of the field.
</p>
<p class="css-8hvvyd">
And on some level, its always going to be harder for, say, putting high speed rail through the middle of California. Right? I mean, just building things in the world is just going to be tougher.
</p>
<p class="css-8hvvyd">
But on the other hand, if you make building things in the world too hard, if you make grants too difficult — if you — I know a lot of doctors who their advice to young people is dont become a doctor. And it always breaks my heart a little bit. We need really great people to be doctors.
</p>
<p class="css-8hvvyd">
And their point is not, dont go heal sick people. Their point is, being a doctor is too hard now. The amount of time you spend dealing with insurance agencies and malpractice insurance and boards, and this and that, its just too much administration.
</p>
<p class="css-8hvvyd">
When industries become very complicated to operate in, you want to select for people who are good at operating complicated industries, which may be different than the people who are good at moving really fast and changing things dramatically. But two, you kind of subtly bias where different kinds of people in your society go. I think in China, if you want to change a lot, you still probably go into infrastructure construction, among other things. Right?
</p>
<p class="css-8hvvyd">
The idea that you might be a genius rail mind, in China, thats great. Theres probably a lot of rail you can make. Thats not true here. And the point is not to make too much of the rail example, but to make a lot of the idea that talent flows towards where it can have an effect and people can live the kinds of heroic lives they want to lead. And if we have subtly pushed a lot of people into maybe not the right — not the socially optimal directions, that over time will have a pretty big effect on a society.
</p>
</dd>
<dt class="css-xx7kwh">
patrick collison
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
I think a constant is that some number of ambitious young people will want to do something, as you say, heroic. And yeah, I think maybe two things have changed. For one, for whatever reason, our predisposition to putting those people in positions of authority has diminished. And then secondly, even if placed, their ability to actually execute, again for various reasons, has been attenuated.
</p>
<p class="css-8hvvyd">
Ive been reading about the university founders and presidents and those associated with some of the great US research institutions. And one thing that is striking is how many of them were so young when placed in those positions of authority. You know, Daniel Coit Gilman at Johns Hopkins, or William Rainey Harper at the University of Chicago. I think he was 32 when he was appointed president of the University of Chicago. Even in the recent past.
</p>
<p class="css-8hvvyd">
So my dad was in the first year of the University of Limerick in Ireland. Or at the time, it was called N.I.H.E. It kind of acquired university status later in its life. And the Irish guy who founded it and was really the dynamo behind it, I think he was 29 when he was put in charge of that project.
</p>
<p class="css-8hvvyd">
And I think it was in 1970 or 71 that he was charged with this mission. But as recently as 1970 in Ireland, we were willing to put a 29-year-old — I mean, thats a person meaningfully younger than me in charge of the project of overseeing the creation of a major new research institution. And I dont know that I have compelling or confident observations to offer in terms of the etiology underlying these changes. But I think the changes themselves are important, or at least we should assume theyre important if we come from a place of humility, where this is what has worked in the past. Enabling these ambitious young people who are willing to contemplate spending multiple decades in pursuit of some ambitious and idiosyncratic vision.
</p>
<p class="css-8hvvyd">
And maybe were more enlightened now. Maybe we figured out how to get all the same innovation and all the same breakthroughs without unleashing that force. But I guess my starting point, at least, would be, well, we should — before getting super confident in that or before really being deliberate about it, I think we should give some kind of credit and credence to the prescription and the methodology thats worked heretofore.
</p>
</dd>
<dt class="css-xx7kwh">
ezra klein
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
And before books, let me end on this. Weve talked a lot about scientific slowdown, about technological slowdown. But lets say in the next 15-year time frame, what are the three technological or scientific possibilities youre most excited by? If in 20 — I guess itd be 2037, were having a conversation about how dumb this conversation was because it was right on the cusp of so much incredible stuff happening, what do you think is likely to be on that list?
</p>
</dd>
<dt class="css-xx7kwh">
patrick collison
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
I dont know that Ive super non-consensus answers. I think that there are fundamental a priori reasons to believe that the rate of progress in biology could increase substantially over the years, and to your question, kind of decades to come. So if in 2037 we are enormously impressed and struck by the discontinuity there, that would not shock me.
</p>
<p class="css-8hvvyd">
Clearly, over the past couple of years, theres been acceleration in progress in A.I. And kind of far for me to try to point estimate for kind of where that is in 2037. But I would be surprised if that is not somewhere on that list.
</p>
<p class="css-8hvvyd">
And then I think theres something about education in the broadest sense that feels to me like a very significant, and hopefully very positive change happening in the world right now. Maybe best embodied by YouTube. But also by Twitter and by blogs and Substacks and even Zoom and kind of the growing ease of being in some kind of cultural proximity to people one aspires to emulating, or following in the footsteps of, or otherwise kind of being more like.
</p>
<p class="css-8hvvyd">
And to the extent that one believes my story about the significance of sociology, and culture, and mentorship, and the kind of delicate transmission of tacit knowledge, it has until very recently only been possible for that to happen to a meaningful extent through physical co-location. And the fact that weve now thrown open those doors to such an extent feels to me like a really compelling and plausibly transformative change. And if it were the case in 2037 that we have multiplied by 20 the number of people who can — who have the initial mental models and understanding to become successful entrepreneurs, or successful scientists, or successful writers, or successful in whatever one might choose ones domain to be, again, I think that would not be shocking. And I think its a pretty hopeful fact about the world.
</p>
</dd>
<dt class="css-xx7kwh">
ezra klein
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
And then always our final question. What are the three books youd recommend to the audience?
</p>
</dd>
<dt class="css-xx7kwh">
patrick collison
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
Well, Im right now reading “Revolution and Empire,” which is a book about Edmund Burke. And it is just fabulous. I very highly recommend it.
</p>
<p class="css-8hvvyd">
Edmund Burke, Irelands foremost political philosopher. And Im embarrassed to say that I have known less about him than I feel like I ought to have. So I recommend that very highly.
</p>
<p class="css-8hvvyd">
And the autobiography by Warren Weaver, who I mentioned, at Rockefeller. I cant remember if its called “Scene of Change” or “Scene of the Action.” But its Warren Weavers autobiography.
</p>
<p class="css-8hvvyd">
Thats not a great book in the sense that you dont read it — you dont find it to be a vivid, compelling page-turner. And your mind is not blown on every page. But I find myself thinking back to it quite a lot and having various parts of it sort of ricochet to my mind.
</p>
<p class="css-8hvvyd">
And then it all depends on what people are interested in and all the rest. And you should read the things you like. But I have on my desk at home right now “A Widening Sphere,” which is a history of M.I.T. And I was re-reading it recently. And my —
</p>
</dd>
<dt class="css-xx7kwh">
ezra klein
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
Who doesnt re-read the histories of M.I.T.?
</p>
</dd>
<dt class="css-xx7kwh">
patrick collison
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
[LAUGHS] Well, William Barton Rogers, the founder, was the son of an Irishman, and started M.I.T. substantially with his brother. And I find it very inspiring, I guess back to what we were saying earlier, how motivated he was and they were by a kind of broad-based desire for societal betterment. Like, M.I.T. didnt inadvertently end up being a significant contribution to American prosperity and ingenuity and welfare. He was really immersed in that milieu.
</p>
<p class="css-8hvvyd">
He paid a lot of attention to some of the cultural dynamics we were describing in England, and the Darwins. And the early writing on M.I.T., if you go and just read the first two pages of the founding manifesto, it wasnt utopian in some kind of implausibly lofty sense. But it was somebody who knew they werent founding a run of the mill nth technical college.
</p>
<p class="css-8hvvyd">
And I feel like its easy to get cynical always. Its easy to assume that the things that really worked out worked out through happenstance, as opposed to optimism and ambition. But yeah, I find the history of MIT to be a kind of inspiring reminder that sometimes these implausible, lofty, ambitious, long-term initiatives can work out much better than one would hope.
</p>
<p class="css-8hvvyd">
[MUSIC PLAYING]
</p>
</dd>
<dt class="css-xx7kwh">
ezra klein
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
Patrick Collison, thank you very much.
</p>
</dd>
<dt class="css-xx7kwh">
patrick collison
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
Thanks for having me. [MUSIC PLAYING]
</p>
</dd>
<dt class="css-xx7kwh">
ezra klein
</dt>
<dd class="css-4gvq6l">
<p class="css-8hvvyd">
“The Ezra Klein Show” is produced by Annie Galvin and Rogé Karma. Fact-checking by Michelle Harris, Mary Marge Locker and Kate Sinclair. Original music by Isaac Jones.
</p>
<p class="css-8hvvyd">
Mixing by Sonia Herrero, Isaac Jones and Carole Sabouraud. Audience strategy by Shannon Busta. Special thanks to Kristin Lin and Kristina Samulewski.
</p>
<p class="css-8hvvyd">
[MUSIC PLAYING]
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EZRA KLEIN: Im Ezra Klein. This is “The Ezra Klein Show.”
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This is a great conversation today. But its a tricky one to introduce, because the guest I have — Im not having him on for the thing hes best known for. So Patrick Collison — by day, co-founder and C.E.O. of the multibillion-dollar payments company, Stripe; by night, by weekend, I think, one of the most important thinkers now in Silicon Valley — certainly, one of the most quietly influential, someone who is forging and traversing an intellectual path that a lot of other people are now following.
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And its this second incarnation and role that Im really interviewing him in today — the soft power side, I guess, of Patrick Collison. Collisons work here centers around this question of progress. The argument is that human progress is much more precious and rare and fragile than we realize.
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We maybe take it for granted. We live in this time when things have been changing, atop decades and decades, even centuries and centuries, even millennia now, when things have kept changing. But for most of human history, that was not true. It was not true.
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There just was no market rapid advance in human living standards. Its only in the past 10,000 years, and then practically in the past few hundred — just an eye-blink in the time human beings have been on Earth — that things kept changing, usually for the better. And the question is, why?
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And Collisons particular meta question is, given the clear fragility of forward motion here, given how rare it has proven to be — and so how easy it might be to lose — why isnt the question of the conditions of progress more central? Why isnt the study of progress in a wide multidisciplinary way a more common and central discipline?
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Collison has written a few influential essays here, with the economist Tyler Cowen. He called for the inauguration of a discipline — they call it progress studies — and that now has people studying it. Theres people creating journals for it, creating syllabi and podcasts and books around the topic. Its one of the more singularly successful calls for a research direction I have seen.
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Separately, in a piece co-authored with the scientist, Michael Nielsen, Collison and Nielsen argued that, though it is hard to measure, it seems like the rate of scientific progress is slowing down, and thats particularly true if you account for how much more were putting into science, in terms of money, of people, of time and technology.
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Now, these ideas are not original to Collison. The point is not that nobody studied human progress before this or worried about the pace of scientific research. He wouldnt claim that. It wouldnt be true. But he is playing a distinctive role in their framing and their popularization, and in creating and funding a community around them.
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And what I see in my travels here is that it is working. Something is burbling here. But I cant find many big pieces where Collison really lays out his worldview. There are a couple essays, tweets, interviews, but hes not been primarily writing this down.
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What he has been doing is funding it through Fast Grants, which has been successful, but more than that, intellectually influential effort to show you can give out scientific grants quickly and with very little overhead, through the Arc Institute, a big biotech organization hes creating to push a researcher-first approach to biotech, and through giving a bit of money, and a bit of time, and a bit of prestige, and a bit of networking to a lot of different projects that circle these questions.
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Hes got this funny quality of being nowhere in particular, but also somehow, almost everywhere, if youre interested in these questions. So what I wanted to do in this conversation was try to get as close as I could to the Patrick Collison worldview, the underlying theory of the case here that animates his thinking his funding, and the ways in which hes trying to nudge the culture hes a part of, or the ways in which hes trying to actively create a culture he doesnt yet see.
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As always, my email — ezrakleinshow@nytimes.com.
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Patrick Collison, welcome to the show.
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PATRICK COLLISON: Great to be back.
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EZRA KLEIN: So youve made the argument that science — all science — is slowing down, that were putting more money and more people into research, and were getting less and less out of it. Tell me about that.
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PATRICK COLLISON: Well, I want to separate two things. Theres a question as to whether science in its totality is slowing down, in terms of the absolute returns from it. I think that might be true. You can maybe divide up the first half of the 20th century and the second half and so on, and sort of try to compare one with the other.
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And we had general relativity and quantum mechanics and various other major breakthroughs in the first half. You can ask the question of, well, did we have as many in the second half? But in the second half, we did have the discovery of D.N.A. and molecular biology and lots of other things.
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So I dont know that I would claim a total slowdown. The thing that I think is clearer and should be very concerning to us is, as you look at the number of scientists engaged in the pursuit of science, and if you look at the total amount that were spending, and as you look at the total output, as coarsely measured by things like papers and number of journals, all of those metrics have grown by, depending on the number, lets say, between 20 and 100x between 1950 and, say, 2010.
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And if you look at it on a per-capita basis, or a per-unit-of-work basis, now used to divide all those total outcomes by a factor of 50, and it seems like if you imagine yourself as the median scientist, youre meaningfully less likely to produce anything like as consequential a breakthrough as you would have, say, in 1920. And so Michael Nielsen and I, in order to try to put slightly more rigor on that question — we went and we surveyed a bunch of scientists across a number of universities in a number of different disciplines, and we presented them with different Nobel Prize-winning breakthroughs.
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And we tried to compute an approximate ordering of their significance in the eyes of these scientists. And the thing that would kind of have to be true — for the per-capita impact, we remain in constant — is wed have to be discovering much more important things in the latter half of the 20th century in order to compensate for, to make it worthwhile, for us to be investing this 50-fold greater effort.
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<p class="css-at9mc1 evys1bk0">
And we didnt find that. In physics, in the estimation of physicists, there was a kind of flat-to-declining trend. Its not super obvious which way it points, but in as much as theres a trend visible, its probably slightly downwards. And in other fields, it was maybe similarly equivocal, perhaps a slight increase, visible in some, but importantly, in no fields that it looked like were on this crazy, exponentially improving trajectory, which is what you would have to have for this per-capita phenomenon to not be present.
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And I think that should be something were interested in for multiple reasons. One, because presumably, as a society, were interested in just how much more scientific progress and technological progress and so forth, how much more innovation is there going to be over the next 10 years or the next 50 years or the next century. But also, because theres kind of two possibilities. One possibility is, fundamentally, were running out of low-hanging fruit, and its just going to be harder to do this stuff.
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And in as much as were setting investment or making investment decisions around to what degree should be pursuing the stuff, I guess its important to know what we think the returns should be. Or the other possibility is, somehow, were doing it suboptimally. Something changed, and we were pursuing this process of discovery more effectively in the past, and presumably, for inadvertent reasons, something went wrong, and now, were just less efficient at it.
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But either explanation — and it doesnt necessarily have to be fully binary — but either explanation is important, and either explanation, I think, has prescriptions for what we should do going forward.
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EZRA KLEIN: Let me start with the low-hanging-fruit explanation, which I think is a more popular one. And you have — in the piece you did on this with Michael Nielsen, the sad, but in the very academic way, very funny quote from the physicist Paul Dirac, who says of the 1920s, there was a time when, quote, “Even second-rate physicists could make first-rate discoveries,” which I just kind of love.
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But the theory there is you can only make a lot of the big discoveries once. You discover quantum mechanics once. You discover the atom once. And most of them have just been made, so what you have now is more complicated, smaller, requires much larger teams of people, much more complicated experiments, with much more infrastructure.
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So were just structurally in a period where its going to get harder and harder and harder to make big gains. Do you believe that?
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PATRICK COLLISON: I think its possible, but even though its intuitively compelling on some level, Im not sure that its true. Its probably true to at least some degree for some particular research direction, right? We go after discovering the various subatomic particles, and initially, without too much difficulty, we discover the electron or whatever.
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And by the time weve discovered the nth quark, its now gotten super hard, and even with ever-larger particle accelerators, were not necessarily making breakthroughs of the same magnitude. So I think its pretty true for a given direction. But obviously, the question is, well, to what degree is progress in any area opening up other directions, right?
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<p class="css-at9mc1 evys1bk0">
And so I mean, you mentioned the Dirac quote and, say, physics in the early part of the 20th century. Those discoveries opened up new techniques and investigation methodologies and so on, that then gave rise to molecular biology in the 50s, 60s and 70s. And so theres kind of a combinatorial benefit, where discoveries over here or discoveries over there might unlock opportunities and major breakthroughs in areas that we could not have foreseen in advance.
</p>
<p class="css-at9mc1 evys1bk0">
There are lots of, quote unquote, “low-hanging-fruit discoveries” made in computers and computer science in the 70s, 80s, and 90s. Maybe were even still in that regime, right? Were still making some pretty fundamental breakthroughs. And of course, again, those, quote, “low-hanging discoveries” would not have been possible without a lot of this optimization and discovery in other fields.
</p>
<p class="css-at9mc1 evys1bk0">
And so I think its probably true for a given research direction, but the relevant question for society is, is it true in aggregate. And there, its much less clear to me that it is.
</p>
<p class="css-at9mc1 evys1bk0">
EZRA KLEIN: I want to read something provocative you said in an interview with the economist Noah Smith. And you said, quote, “Most systems get worse in at least certain ways as they scale. The idea that science could have gotten worse in significant ways sometimes sounds strange to people. Like, were doing so much more. How could that be bad? But I think that misses the many examples of sensitivity of scientific processes to institutions and culture. Swiss nationals have won more than 10 times more science Nobels per capita than Italians have. 10 times. And yet, theyre neighbors. And Italy certainly isnt lacking in scientific tradition — Fermi, Galileo, the oldest university in Europe, et cetera. The how of science just really matters.”
</p>
<p class="css-at9mc1 evys1bk0">
And this seems, to me, to be where your exploration really goes. So tell me what you think might have gone wrong in the “how” of science.
</p>
<p class="css-at9mc1 evys1bk0">
PATRICK COLLISON: So I think this point about the sensitivity of scientific outcomes to the specifics of the institutions and the cultures is very important and probably underappreciated. At the beginning of the 20th century, not only was the U.S. not a scientific powerhouse, but it barely had a presence in frontier research, whatsoever.
</p>
<p class="css-at9mc1 evys1bk0">
To become a credible researcher in the U.S. in 1900, you almost certainly had to go and spend time in, most likely, Germany, and failing that, in France or England — you know, what have you. And by 1900, the U.S. was already a pretty prosperous place, and it had a well-educated society, as societies went.
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<p class="css-at9mc1 evys1bk0">
And yet, somehow — and it had universities, right? I mean, Harvard was hundreds of years old by that time. And so it checked many of the ostensible boxes, and yet, the sum total of the U.S. research output as of 1900 was still de minimis.
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<p class="css-at9mc1 evys1bk0">
When James Conant, who was later president of Harvard for 20 years — when he went to Germany as a chemist, which was his original training, in the 1920s, he recounts how dispirited he was by what he found there and how far ahead of Harvard German research was, as of the early 20th century. And then, for a variety of reasons, all sorts of cultural, institutional funding — various transformations happened. And of course, by the latter half of the 20th century, the U.S. was the unquestioned leader at the frontier of scientific progress.
</p>
<p class="css-at9mc1 evys1bk0">
If you look backwards, you see where that locus has been, where the most successful and fertile scientific grounds have been — it has repeatedly moved. As we just said, maybe the 19th century, it was Germany.
</p>
<p class="css-at9mc1 evys1bk0">
Before that, in the 18th century, it was plausibly France. They had a couple of these really successful École Polytechnique and Grande École and so on. And so as a kind of first-order empirical matter, we can just notice, huh, this really seems to matter — and then, the example you just gave of the divergence between Switzerland and Italy.
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<p class="css-at9mc1 evys1bk0">
And so then, if we kind of accept that, and we try to ask ourselves, well, specifically, what are the mechanisms? You know, whats actually going on? Its hard for me to say. It seems like the transmission of research culture by individual researchers matters a great deal.
</p>
<p class="css-at9mc1 evys1bk0">
And you see these kinds of pockets of the cultural transmission repeatedly crop up, where Gerty and Carl Cori — you probably havent heard of — they ran a little biology lab in Missouri, and no fewer than six of their trainees, of students they trained, went on themselves again to win Nobel Prizes.
</p>
<p class="css-at9mc1 evys1bk0">
And if we tell ourselves a standard kind of mechanistic story as to, well, its the funding level, its how much are we investing in science, or its something about whether theres an institution in the courser sense, that can possibly be amenable to it, its very hard to explain these eddies where you see these pockets of excellence really produce these outsized returns. So I think its a complicated question.
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<p class="css-at9mc1 evys1bk0">
I think all of aggregate culture, funding, institutional characteristics, and so on all contribute to it. But if I had to isolate a single variable, it seems to me that the research culture set by specific people and the tacit knowledge transmitted through direct experience is probably the number-one thing.
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<p class="css-at9mc1 evys1bk0">
EZRA KLEIN: This, I think, is where I sometimes fall into my own pessimism on this. Because I want to believe, as you do, that we can double the rate of scientific advance, maybe even go further than that. But I think the prediction — if Im putting this on institutions, on culture, on pockets of transmission and mentorship — I think the prediction I would make is then, even if you believe, say, that America had a great 20th century, but its institutions have become sclerotic, and weve slowed down, and everything is piled in lawsuits and review boards now, somewhere else that didnt have that, that has a different culture, that has different institutions, would be pulling way ahead.
</p>
<p class="css-at9mc1 evys1bk0">
So you might think, well, China will be pulling way ahead. And youve noted this in some places. Were getting a lot of peer-reviewed research out of China — huge number of citations out of China. Were not seeing them dominate the big breakthrough advances of the era.
</p>
<p class="css-at9mc1 evys1bk0">
It doesnt seem like Europe is lapping us. And so if you think this slowdown is somewhat global, then that seems to me to militate against questions of individual institutions, cultures, how different labs work, because there is so much variation that you should have some of these labs that are doing it right, some of these places that havent piled on a little bit too much bureaucracy. But I dont think we really see that.
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<p class="css-at9mc1 evys1bk0">
PATRICK COLLISON: This diagnosis of these phenomena to cultural, institutional, mentorship-related, interpersonal dynamics, and your observation that its not obviously the case, that there are other places we can pointed that are doing it so much better — for me, my takeaway is that, well, successful cultures are a pretty narrow path. Homo sapiens emerged 200,000 years ago.
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<p class="css-at9mc1 evys1bk0">
And as far as we can tell, for the first 190,000 years of our genesis, we think we were largely biologically equivalent to the people we are today. But as best we can tell, there was some kind of cultural capital that those people lacked for a very extended period of time before human societies in somewhat recognizable modern form started to emerge — agriculture, all the rest.
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<p class="css-at9mc1 evys1bk0">
And in a similar vein, we had many billions of lives and centuries elapsed before the Industrial Revolution., and before we started to put together many of the input ingredients or enough of the input ingredients that we can get sustained improvement in standards of living and ongoing economic growth and progress. And so your point about, well, as I look around, I dont see anything or anywhere thats obviously better, I agree with that.
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<p class="css-at9mc1 evys1bk0">
But again, my takeaway is that thats what makes the question of how do we improve or how can we do somewhat better so urgent and pressing, where its many things have to go right. Its not easy to be even as good as — or to get to a place where things are as good as they are today. What we have is very precious. And I think the threads and the themes that youve been pulling on of late — all of these dynamics underscore their importance.
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<p class="css-at9mc1 evys1bk0">
EZRA KLEIN: I think thats a good bridge to progress studies as an idea. And I want to have people hold in their heads that idea that progress is very narrow, that it is a very narrow bridge that we have walked on for a very short period of time. But lets try to define it.
</p>
<p class="css-at9mc1 evys1bk0">
When you say progress here, what are you actually talking about? Is it just shorthand for economic growth or G.D.P.? What is progress?
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<p class="css-at9mc1 evys1bk0">
PATRICK COLLISON: Well, I dont know that I would claim to put forth some kind of definitive definition. And I think, to some extent, our intuitions around it are probably broadly correct. And so it might not matter to define it super precisely and finely.
</p>
<p class="css-at9mc1 evys1bk0">
For, me it is something along the lines of our success in realizing a liberal, pluralistic and prosperous society, and a sense among people that their offspring can and probably will do better than they themselves have, and that more broadly, the future will be better than the past, and that were at least making incremental progress towards embodying values and morals that we collectively think we can be proud of.
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<p class="css-at9mc1 evys1bk0">
But I dont think anything that novel in that. I dont think my conception of progress would differ that materially from some kind of average aggregate over any other group of people in the country.
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EZRA KLEIN: I do think theres something interesting, though, which is that if you look at eras that I think progress-studies-type people and economic-growth people and historians of economic growth study most closely, actually, some of the periods where people feel a lot of rapid progress dont fit that at all. You have, say, the Industrial Revolution, where life spans and lifestyle get worse for a lot of the people.
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<p class="css-at9mc1 evys1bk0">
I dont think one will look at that period as unbelievably pluralistic. You have a lot of periods of war when you have very, very, very rapid technological progress, but it happens in context of much more martial societies. So there is an interesting tension, at least in periods — and some of them quite long, actually — where you can have fairly rapid economic progress, but it comes at a cost that I think isnt always acknowledged, but is an important thing to think about.
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<p class="css-at9mc1 evys1bk0">
PATRICK COLLISON: Yeah. So I dont think you could point to some of these periods in the past and say that they definitively embody to the extent that we would fully aspire to some of these broader traits and characteristics. But I think the question is more, what are they doing as — you have to judge it relative to the baseline that preceded them.
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<p class="css-at9mc1 evys1bk0">
And I dont know that the 18th century in the U.K. is some ideal as a society. But if you compare it to the 16th century in the U.K., the ideals and ideas of natural rights and religious tolerance and so on — they were somewhat better embodied by the 18th century than they had just a couple of centuries previously.
</p>
<p class="css-at9mc1 evys1bk0">
And similarly, in the U.S., say, during either war or the 30s or whatever, again, its not like that was any kind of perfect society, but assessed relative to the society of 1830, I think it compares relatively favorably. And I think its not a coincidence that Adam Smith — his first book, of course, was on ethics and morals and trying to instill better general ideals and behaviors across a society.
</p>
<p class="css-at9mc1 evys1bk0">
And maybe after that, he then argued for and laid many of the foundations of what we would recognize as modern economics. So I dont think its perfect. But on average, I think the correlation is positive.
</p>
<p class="css-at9mc1 evys1bk0">
EZRA KLEIN: So lets talk about the Industrial Revolution for a little bit here. I think a lot of people locate a takeoff in human living standards — it continues to this day — there. And its strange in a way, right? “There” is a very geographically contiguous spot. Its the U.K. — England, actually, I should say, at that point.
</p>
<p class="css-at9mc1 evys1bk0">
And there is a moment in time that probably could have come at another moment in time, depending on how human history plays out in the counterfactual. I know that you have an interest in the theories of why then, why there. How do you work your way through them? What do you think is persuasive for why then, why there?
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PATRICK COLLISON: Well, you know, again, I caveat. With all of these topics were discussing through this podcast, maybe the first-order banner for all of them should be, I dont know, these are my best guesses, and I think its important that all of us were pretty humble in the claims and the assertions and the beliefs that we hold.
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<p class="css-at9mc1 evys1bk0">
Recently, Ive been reading a bunch of Irish and Scottish writers around then. Its very interesting, because for both the Irish and the Scots, there was a sort of a pressing and kind of obvious question where England was much more prosperous than they were or we were. And theres no super obvious explanation for that. There wasnt an obvious climatic or natural resource endowment that England benefited from that was lacking in Ireland or Scotland.
</p>
<p class="css-at9mc1 evys1bk0">
It wasnt like England was actually a vastly larger polity. The orders of magnitude were comparable. And Bishop Berkeley wrote this book, “The Querist.” He was asking these questions directly, just like, whats going on? Whats wrong with Ireland? You know, why cant we do this?
</p>
<p class="css-at9mc1 evys1bk0">
And then, you have the Act of Union in 1707, uniting Scotland and England — and sort of similarly, of all these Scottish thinkers being like, all right, were now literally the same country. Why are we so much more impoverished? And then, if you shift to England, theres Joel Mokyr and — youve read his work — and more recently, people like Anton Howes.
</p>
<p class="css-at9mc1 evys1bk0">
And in a similar vein, they go back to — I mean, the word, improvement, came from Francis Bacon, or it was kind of popularized as a concept by Francis Bacon. But thats noteworthy, right? Like, that was not a pervasive broad concept in the 15th century.
</p>
<p class="css-at9mc1 evys1bk0">
I mean, literally, the word, improvement, in this broader societal context, came from word, “translated,” at the beginning of the 17th century. And the ultimate conclusion that these historians and scholars and analysts of the Industrial Revolution come to — and I think its a correct one — is somehow, whether its through Bacon or Newton or various of the tinkerers who produced some of the earliest technological breakthroughs, that somehow, this improving mind-set became pervasive.
</p>
<p class="css-at9mc1 evys1bk0">
You had societies explicitly — like the Hartlib Circle or the Lunar Society, or the Select Society, and the club, and so on — all these societies explicitly devoted to figuring out ways to advance the state of affairs that prevailed. And these societies were comprised of many of the leading people and thinkers and so on of the day.
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<p class="css-at9mc1 evys1bk0">
And it seems maybe a bit satisfyingly squishy to attribute it to something so hard to pin down. But as you run through all the possible other explanations, its differences in IP law. Its difference in the Malthusian conditions. Its difference in the prevalence of coal, you know, et cetera, et cetera. Through various cross-sectional analyses, you can exclude most of these in looking at all of Ireland, Scotland, and England.
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<p class="css-at9mc1 evys1bk0">
It really does seem to me that differences in the mind-set and in the culture are where you have to net out. And thats not to say maybe that its fully sufficient. There might be other preconditions that are important. And then, maybe as a last thing to say, it is striking to me that many of these kind of original 18th-century economic writers and thinkers — and again, the kind of people we look to as the founders of much of the discipline — that they themselves were kind of centrally preoccupied with this.
</p>
<p class="css-at9mc1 evys1bk0">
And yeah, they were in favor of free trade and specialization and human labor and lots of these concepts that were now very familiar with, but they really thought that general mind-set played a big role, too.
</p>
<p class="css-at9mc1 evys1bk0">
EZRA KLEIN: So lets talk about Joel Mokyr ideas for a minute. So Mokyr is an economic historian. People should read his book, “The Culture of Growth,” which is really fascinating. He argues, as youre saying, that in this period, this mind-set that we can increase the store of usable knowledge, and then use it to alter nature, to better the human condition, takes hold.
</p>
<p class="css-at9mc1 evys1bk0">
Thats a new mind-set. Its different than religious ideas of the past. Its different than cultural ideas of the present. And that, plus a bunch of other things, particularly the republic of letters, the way people are writing letters back and forth, kind of combine into a culture that is able to grow.
</p>
<p class="css-at9mc1 evys1bk0">
But one of the things that I really take from his work, that sits in my head, is he believes its all very contingent. He really believes it might have not happened. But the other is that I think it opens up this question that as a tech person, Im curious to hear your thoughts on, which is, he really believes — Mokyr really believes — that there is a communications infrastructure that arises at that time, that has a kind of culture of generosity and argument and honesty in it, and is built on writing letters slowly to one another, and then copying those letters over to other people.
</p>
<p class="css-at9mc1 evys1bk0">
And that culture is really good for intellectual advancement. I think one of the promises of the internet and the age we live in is, its all faster. We can write to people immediately. Things we write can go viral and be seen by 5 million people all of a sudden.
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<p class="css-at9mc1 evys1bk0">
And that was going to speed up economic growth really, really rapidly. And I would say, you dont see that. So Im curious how you think about communication cultures here and what you think for all the advantages of ours we might not have.
</p>
<p class="css-at9mc1 evys1bk0">
PATRICK COLLISON: I mean, I think its hard to say in aggregate. I feel its pretty likely that the effects are very heterogeneous across different populations. And youve made the case that you think Twitter is bad for journalism and for journalists.
</p>
<p class="css-at9mc1 evys1bk0">
And I guess you live this yourself with your now mostly inactive Twitter account, I guess, apart from announcements. And I think in the case of the internet, that its almost certainly a tremendously large gain that billions of people now have access to educational materials. And some of the otherwise hard-to-communicate tacit knowledge — that things like YouTube videos now made legible and available.
</p>
<p class="css-at9mc1 evys1bk0">
And I think its true that there are various gravity equations that we see across different disciplines. I mean, in economies themselves, in trade, where you rapidly decline in propensities to trade as countries get further from each other — but you have versions of this in academic disciplines as well, where geographic distance correlates inversely with likelihood of the exchange of ideas and so on.
</p>
<p class="css-at9mc1 evys1bk0">
And I think its clearly the case that the sort of reaction surface area has increased substantially by the internet there and represents a kind of efficiency gain for people looking to exchange in ideas. Many of the companies that Stripe works with are remote companies, and they might employ people across myriad countries, and thats a kind of communication and efficiency gain that would certainly not otherwise be achievable.
</p>
<p class="css-at9mc1 evys1bk0">
I think its worth recognizing that the aggregate amount of G.D.P. that we are creating or gaining every year is so much larger now than — I mean, the percentage might be the same. But the total amount of stuff happening, or the increasing amount of stuff happening, is so much larger now than it was 100 or 200 or 300 years ago.
</p>
<p class="css-at9mc1 evys1bk0">
And so for all of those reasons, I think we should give superior communication technologies and faster communication technologies a significant amount of credit, even though the ways in which those are manifests might be hard to measure and somewhat prosaic.
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Take my mom, for example. My mom works with a hospital in Minnesota. Our youngest brother has a physical disability. And in the course of that, she trained herself in treatment for cerebral palsy, this condition, and she wrote a book about it, and she did a masters in this. And now, shes trying to improve treatment for this condition throughout Ireland, in the U.S. and other countries as well.
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Shes a retired Irish mother who spends some of her year living in the U.S. near her sons, spends the rest of her year living in Ireland, working at a hospital in Minnesota, who just got a proposal to have her book translated into German a couple of days ago. And thats a relatively prosaic story, but literally, millions of these stories exist in kind of aggregate form around the world.
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<p class="css-at9mc1 evys1bk0">
To circle back to the initial thrust of your question, though, I think its at least possible that the internet is bad for civic discourse. Im not saying it is, but its certainly in the realm of plausibility — and that perhaps both things are true, where theres some kind of iceberg where there are these enormous welfare gains that are not that legible, not that visible, lie beneath the surface, and then certain of the most visible manifestations, like what we see on cable news or what we see written in the papers — perhaps that is worse, and perhaps, slightly more structural judiciousness would be desirable there.
</p>
<p class="css-at9mc1 evys1bk0">
EZRA KLEIN: I want to try to flip that and suggest that — because Im going to push some counter ideas on why we maybe dont see as much progress as we wish we did. But one is that I think possibly, very large welfare losses lie beneath the surface. And beneath the surface of stories like the one you just told about your mother, I think we all have stories of ways or people for whom the internet has unlocked a possibility.
</p>
<p class="css-at9mc1 evys1bk0">
I mean, my whole career is built on the internet. I was an early blogger. I got rejected from my student newspaper. And if there was no blogging, like, god knows what would have happened to me. [LAUGHS] I mean, nothing too terrible, probably, but I wouldnt have the career I have today.
</p>
<p class="css-at9mc1 evys1bk0">
And at the same time, I think that the group of people who, by luck or by temperament, proved very, very good at using the internet, to some degree, distracts from the many, many, many people for whom the internet is fundamentally a distraction machine, or for whom the internet is creating, because of what we built on it. You know, shorter attention spans — how many people would have had an idea, sitting in a room by themselves, or taking a walk, that they never have now, because they never have to have a moment where theyre thinking alone?
</p>
<p class="css-at9mc1 evys1bk0">
And so one thing that I think were all loathe to do is well talk a lot about how its weird that we have so much more knowledge, but productivity isnt increasing faster. Its weird that we have so much more rapid communication between researchers, but science isnt advancing faster. And then, the idea that maybe there are things happening to us that makes us less able to use that increasing stock of knowledge well, or makes us less able to collaborate in a useful way, I think, gets dismissed rather quickly.
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<p class="css-at9mc1 evys1bk0">
But I dont think its totally implausible. Now, I dont want to say, like, the greatest technology we ever had was letter-writing. Obviously, the greatest technology we ever had was blogging in the early aughts when I became a blogger. And whatever happened in your 20s is, like, as good as it was ever going to get.
</p>
<p class="css-at9mc1 evys1bk0">
But I do wonder about these questions. And I think something Mokyr is right to put a lot of attention on is communicative cultures. Communication is how we collaborate. And if communication is in any way getting worse, its going to have pretty big macro effects.
</p>
<p class="css-at9mc1 evys1bk0">
The other thing is if you believe these cultures matter, weirdly, as big as were getting, the internet allows a certain disciplines culture to stretch boundaries and borders in time in a way that it would have been harder. I suspect that labs were more different 50 years ago than they are today.
</p>
<p class="css-at9mc1 evys1bk0">
The countries and the disciplines of researchers and the cultures of researchers in countries or cities are more different from each other 50 years ago than today, which is great if we have the best of all cultures today, but its not that great if you actually think variation is really important.
</p>
<p class="css-at9mc1 evys1bk0">
PATRICK COLLISON: Lets wrap up there. So first, I agree, as a basic matter, that there are welfare losses occurring across society that we should be worried about, and probably everybody listening to this is familiar with the Stephen Pinker case for optimism, and rather than focusing in the headlines, you zoom out, look at these long-term time series. And once one does that, things seem a lot more encouraging, whether you look at it by income or life expectancy or infant mortality or choose your metric.
</p>
<p class="css-at9mc1 evys1bk0">
Something thats been striking to me of late is if you change the x-axis on those time series, and look at many of those phenomena and trends over a much shorter window, the valence changes substantially, and life expectancy in the U.S. is now, in fact, declining. According to C.D.C. data, 54 percent of teenage girls now report persistent feelings of sadness and hopelessness. And you could say, well, teenagers were never stereotyped as the most cheerful lot, but we do have some degree of longitudinal data here, and that number is up from being in the 20s as recently as 2009.
</p>
<p class="css-at9mc1 evys1bk0">
½ the population now is either prediabetic or diabetic — again, according to the C.D.C. Basically, point is, when we look at more recent windows, I think there are plenty of aggregate, emergent, complicated outcomes and phenomena that should give us concern. On the degree to which we should attribute the diagnosis to the internet or to our kind of communication media more broadly, its less clear to me in that — not saying its not true, but presumably, the life expectancy one is not — or at least if it is, the mechanism has to be very complicated.
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<p class="css-at9mc1 evys1bk0">
There are a bunch of other health-related ones. So take, for example, say, the incidence of diabetes or pre-diabetes. And you could say, OK, fine, all those things might be true, but theyre totally different. I guess the question I wonder about is, well, we know that lots of basic biological outcomes are correlated with mental states and so on.
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<p class="css-at9mc1 evys1bk0">
And so to what degree is there some more nuanced and complicated relationship there? But I think its a fair question, and I wonder a lot about it myself.
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<p class="css-at9mc1 evys1bk0">
EZRA KLEIN: Let me ask you about how you think, over the long period here, about the relationship between technology and equity or egalitarianism. And something specific is in my mind. I flicked earlier at the way the Industrial Revolution, for an extended period of time, seems to have reduced a lot of peoples living standards. And it wasnt till later you had changes in redistribution in labor unions and labor protections that the amount of material prosperity that was generating created more broad-based prosperity, particularly at a very high level.
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<p class="css-at9mc1 evys1bk0">
I dont know that you can sustain that kind of thing today. We have much more a small-d democratic culture. If things arent working for people, its much easier for them to organize and be heard.
</p>
<p class="css-at9mc1 evys1bk0">
I think theres a much more direct and complicated relationship now between whether or not people feel benefited by technology, and whether or not they are going to accept the conditions and the risks of rapid technological advance. But Im curious, from your vantage point, how you see that both kind of historically and currently.
</p>
<p class="css-at9mc1 evys1bk0">
PATRICK COLLISON: I agree with that. I worry a lot about the basic stability of a society that does not successfully generate and make sufficiently broadly accessible the benefits of economic growth. The world simply has too little prosperity. And if it is not the case that people in the U.S. or people in any country — if they either feel like things arent progressing, or if they feel like maybe somewhere distant from them, things are progressing but they personally will never be able to benefit from it, I think we put ourselves in a very dangerous and likely unstable equilibrium.
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<p class="css-at9mc1 evys1bk0">
And if you go back to — well, you dont have to go back very far in history to see, obviously, plenty of instances where this kind of instability brought the whole house of cards down. And so as a consequence of that, I worry a lot about, how do we simply make sure that — or one of the small things we each individually can do to try to make sure that society is generating enough economic gain and enough broadly experienced welfare gain that the whole compact can be maintained?
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And again, I dont think theres a ready neat kind of singular answer to that. Maybe Stripe as part of our small little contribution in one little fissure. But I think the central question youre getting at is super important.
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EZRA KLEIN: And one of the questions I wonder about there — weve talked about the way progress has been very geographically lumpy, lets call it, right? Theres a lot that happens in very small places, and it ends up affecting the whole world. Obviously, then, the gains of progress sometimes have that quality, too.
</p>
<p class="css-at9mc1 evys1bk0">
And I do think of one of the politically destabilizing effects of the past, lets call it, 30 or 40 years of digital progress, is being the concentrations of wealth. We just used to have a lot more spread. Even putting the questions of rising inequality aside, just where rich people were was different.
</p>
<p class="css-at9mc1 evys1bk0">
And so where they were giving a lot of money to the local hospital was more spread out, say, across the country or in other countries across the land. But here, even as the internet is supposed to democratize distance, and in many ways, has — I mean, telework is not a fake phenomenon. It has really concentrated the wealth of that to, literally, where were sitting, but to New York. Theres a lot of money now in Austin.
</p>
<p class="css-at9mc1 evys1bk0">
And then, on top of that, you often have barriers of entry, in terms of how many homes can be bought. So its not even like people can move to the place where all the economic opportunity is happening. And I do think that creates some of the skepticism you see of technology.
</p>
<p class="css-at9mc1 evys1bk0">
I dont think a lot of peoples — I think people are really excited about a lot of the goods theyve gotten from it. But in this kind of macro political sense, as youre saying, in a period of a lot of change, a lot of folks with real backing in the data dont feel life has gotten better at the macro level.
</p>
<p class="css-at9mc1 evys1bk0">
Life expectancy, happiness, political stability — its not like you can look around and say, well, I got this computer in my pocket, and everything else is going great, too. Its like, I got this computer in my pocket, and what it keeps telling me is that everything is going to hell. Now, maybe its telling me that a little bit too much, but there is validity to the narrative.
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PATRICK COLLISON: Yeah. So again, vehement in agreement on the sort of central importance of making sure that improvements in the standard of living are actually broadly realized across the society. That, too, I think, could serve as a manifesto for some of these Progress Studies ideas.
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<p class="css-at9mc1 evys1bk0">
On the internet in particular, or on technology and the technology sector and so forth, I think its complicated and difficult to try to sort of fully collapse or linearize it or something, where on the one hand, you have some of these concentration dynamics you identify. At the same time, of course, it is also a tremendous and incredible dispersal agent in making some of those possibilities and opportunities be more broadly available.
</p>
<p class="css-at9mc1 evys1bk0">
I think its dangerous to take an excessively U.S.-centric perspective here. If you interact with or look at survey data, or otherwise try to assess whats the sentiment of people in Poland, whats the sentiment of people in India, or whats the sentiment of people in Indonesia, they view the internet extremely positively. And I think correctly so, where their opportunities for advancement would be substantially curtailed in the absence of much of what the internet makes possible.
</p>
<p class="css-at9mc1 evys1bk0">
I think in places like the U.S., or actually, even at home in Ireland, some of this story is complicated by lots of other things, but including — and I think, substantially — dynamics around housing policy, where theres an extensive literature showing that, for example, a very substantial moderating effect on the increase in wealth inequality that would otherwise have happened, or income inequality, was geographic reallocation and people responding rationally to, OK, things in New York are going great, or things in California are going great.
</p>
<p class="css-at9mc1 evys1bk0">
And if you look at the rate of increase of the Californian population, say, through the 1960s, that was a tremendously potent mechanism for us redistributing some of the economic gains that were being realized at the time. And of course, now, we have this crazy position, where California is losing population at the same time where the market caps of these companies and the profits of these companies are increasing very rapidly.
</p>
<p class="css-at9mc1 evys1bk0">
But as one assesses that dynamic and tries to ask the question of, well, why arent these gains being better or more broadly distributed, its certainly not clear to me that the answer even lies in the realm of technology qua technology. And I think its certainly more broadly, again, some of these considerations like geographic allocation.
</p>
<p class="css-at9mc1 evys1bk0">
EZRA KLEIN: Let me ask one more question on the geographic dimension, and then Ill move on to it. And its on my mind, in part because when I try to think about progress, when I try to think about what inventions and innovations are coming really quickly, I actually see a bunch here. And Ill use A.I. as an example.
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Ive met people who are trying to automate a bunch of legal contracts. It makes a ton of sense. People pay a lot all over the country — to some degree, all over the world — to get fairly basic legal contracts drawn up — wills and real estate documents and merger agreements and all kinds of — from the small to the large.
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<p class="css-at9mc1 evys1bk0">
If you imagine that getting really effectively automated, though —
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<p class="css-at9mc1 evys1bk0">
you think about Saint Louis, Missouri, where some of the people who are important pillars of the community work in law firms there, and what they do is contracts. They do estate planning and all the things that people have to do in contracts. And if it actually does get concentrated to really, really great contracting firms in the Bay Area or in New York, on the one hand, the democratizing potential will really be realized. Those contracts will get cheaper.
</p>
<p class="css-at9mc1 evys1bk0">
Theres also a theory in crypto of smart contracts. And on the other hand, you really will have a lot of that — the gains of that, economically, going to smaller areas and aggregated across a bunch of different domains. So graphic design, in all kinds of areas of the country — midlevel graphic designers get paid to make logos for local businesses.
</p>
<p class="css-at9mc1 evys1bk0">
Its pretty clear theyre going to be able to do that really, really easily on things like DALL-E pretty fast. So you can imagine a lot of that area getting wiped out. And you kind of run through a couple of these. And before you get to really unbelievable and sci-fi-like dimensions of artificial intelligence, you just have a thing that is going to democratize a lot of capabilities in a way thats going to put the money for those capabilities both a little bit back into the pockets of the people who need them, and then a lot into the people who run the best A.I. rigs and is going to have a really weird geographically destabilizing effect.
</p>
<p class="css-at9mc1 evys1bk0">
And that paradox of the internet both democratizing geography, and then concentrating wealth and capital in very small areas is, to me, a central challenge. Because if you get that wrong, if it goes too much in the concentration area, I think were going to lose a lot of the political stability we need here. But youre more on top of these technological advances than I am. Do you think the trends there are going to play out differently than Im worried they will?
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<p class="css-at9mc1 evys1bk0">
PATRICK COLLISON: First, yeah, its not — I dont think its foreordained whether or not these are going to be centralized technologies. I dont know. And on the one hand, theres, I think, an obvious feature we can contemplate, where there are only three A.I. models, and they are rooted in the hegemons, the citadels of Silicon Valley technology, and we all are digital serfs who are subsistence-farming on their gains.
</p>
<p class="css-at9mc1 evys1bk0">
I think theres also a very plausible story where these technologies prove substantially less defensible than we might have expected, and where, instead, they have this enormously decentralizing effect. Because otherwise, economies of scale that only large firms could benefit from can now be realized and pursued, even by massively smaller firms. And if we look at the recent history of A.I. — I dont think any clear story there, but it does feel to me that it has been more biased towards the second story than the first.
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<p class="css-at9mc1 evys1bk0">
There are now multiple companies with large language models. There are a number of very successful open-source A.I. efforts. Actually, there was a really cool example from Replit, which is a service — its a programming I.D. in the browser, used by kids learning to code, but also increasingly used by people who are pursuing serious programming.
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<p class="css-at9mc1 evys1bk0">
And they recently released a GitHub copilot-like technology, where it will kind of autocomplete your code in the editor, and where you can do some pretty cool things. Like, you can highlight a block of code and ask it to be explained, and itll turn code into natural language, into English, and say, hey, heres what this code is doing.
</p>
<p class="css-at9mc1 evys1bk0">
Anyway, they wrote a blog post about how they built this, and they describe how it was built by one guy over the course of a couple of weeks. And maybe thats only the case in the early days of this AI technology. I mean, in early computer games, the first games were built by a single heroic person, and now, its these gigantic studios and enormous CapEx budgets.
</p>
<p class="css-at9mc1 evys1bk0">
And so I think the fact that this is the case today doesnt mean that it will remain the case through time. But my takeaway is that at least not foreordained that AI or any of these other technologies will be centralizing forces. And then, the other thing to observe is that when we talk about these being centralizing, I think theres a question as to, do we look at it in relative or absolute terms?
</p>
<p class="css-at9mc1 evys1bk0">
And my contention would be that, both from a moral standpoint, but maybe more importantly from kind of a political-economy standpoint, what will matter is whether, on an absolute basis, people feel like they are realizing opportunities, their lives are improving, that things are getting better, that their kids will be in a better situation and so forth. And exactly how much value is realized by the companies themselves doesnt actually matter that much, compared to that former question.
</p>
<p class="css-at9mc1 evys1bk0">
And whether A.W.S. or whether any of these organizations has super high or super low profit margins, I dont know is nearly as important as what is the actual effect on these communities and individuals across the society. And so in as much as one means — by centralizing, one means a large share of the profits, I think it is probably a more useful framing to look at it instead in terms of absolutes, and in particular, the absolute surplus generated by the users.
</p>
<p class="css-at9mc1 evys1bk0">
[MUSIC PLAYING]
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<p class="css-at9mc1 evys1bk0">
EZRA KLEIN: What have you come to believe about the relationship between progress and war?
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PATRICK COLLISON: I am somewhat skeptical that war is as conducive to breakthroughs as we might intuitively conclude, or as is sometimes claimed. Youre probably familiar with Alexander Fields work on the 30s here. And his basic claim is, the productivity gains we often attribute to the Second World War in the U.S. — like, those foundations actually were laid in the 30s, and then the first half of the 40s were a period of decreasing productivity as we massively, inefficiently reallocated our economic resources for the purposes of winning the war, which was probably a good thing to do, but inefficient in narrow economic terms.
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<p class="css-at9mc1 evys1bk0">
And he has a new book coming out, I think, next month, that sort of extends this argument into the 50s.
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<p class="css-at9mc1 evys1bk0">
And as one takes stock of the scientific breakthroughs — and so Stripe Press recently republished Vannevar Bushs memoir, where he takes stock of this.
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<p class="css-at9mc1 evys1bk0">
And obviously, you have, say, the Manhattan Project, and thats a big deal, certainly. But it doesnt feel to me that had the Manhattan Project not occurred, that peaceful development of nuclear technology would have been massively stymied. Maybe it would have taken another 10 years, but it was already happening to some meaningful extent.
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<p class="css-at9mc1 evys1bk0">
And then, as you take stock of all the other breakthroughs that took place in the U.S. during the Second World War, there were some meaningful stuff like blood plasma and blood transfusions. There was some significant breakthroughs there. Some of the first antimalarial medications, radar, the proximity fuse, which Im not sure is all that useful outside of military applications.
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<p class="css-at9mc1 evys1bk0">
But by the time you get down to invention 6 on the list, I dont know that as you compare that list to, again, some counterfactual of what would otherwise have ensued, that it looks radically better as you take stock of the Cold War and the enormous fraction of our economic resources and human capital that were devoted towards us, that the gains necessarily look that impressive. And so again, its super hard to judge. You dont have proper controls and so on. But Im skeptical.
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<p class="css-at9mc1 evys1bk0">
EZRA KLEIN: Let me take the other side. So theres a question of, during war, how much did we invent during World War II. And thats a question of how much the threat of war or the competition with an adversary ends up charging up innovation and convinces us to put resources, both in terms of people and in terms of money, and maybe in terms of institutions, into projects we wouldnt otherwise have done.
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I think theres an argument, at least, that we went to the moon because of the Soviet Union. It would not have done that for some time. Probably would have eventually done it, but also, who knows?
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<p class="css-at9mc1 evys1bk0">
As Derek Thompson, who Im working on a lot of these ideas with, likes to point out, the Apollo Project was unpopular. It was not something that commanded wide popular support.
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<p class="css-at9mc1 evys1bk0">
Even now, if you look at the CHIPS Act that passed, it passed, with all that spending on semiconductor research and other kinds of next-generation technologies, under the framework of, lets compete more effectively with China. If you look at all the things Darpa has done or been part of, the fact that “defense” is the first word in the Darpa acronym, I think, is meaningful.
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Theres something about what threat persuades societies to do, and persuades them to do technologically or what risks it allows otherwise-more-cautious governments to take, or what failures they could justify that allows them to have big successes. Something there doesnt seem to small to me.
</p>
<p class="css-at9mc1 evys1bk0">
And maybe its my political side, where I so often see scientific funding justified in Congress in terms of countries were competing with or are adversaries with. And I see what the defense industry can do that other institutions cannot, because they dont get a lot of political blowback. But I dont know.
</p>
<p class="css-at9mc1 evys1bk0">
I worry a little bit about how much we seem to need the threat of another to accelerate things. And in a small way, maybe, we see what the pandemic — where we were willing to move much, much quicker on things like mRNA technology than I think we would have outside of it.
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PATRICK COLLISON: Yeah. So I think its certainly true that the crisis can cause the discontinuous shifts that have large effects, which in your example, say, are probably super beneficial. I dont know. If you take Darpa as an example, it started as Arpa, as a more open-ended research institution and set of programs, and then with the Vietnam War, had the D pretended to it.
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And we decided, in the face of threat, to make it more applied, to take more seriously its translational and kind of, quote unquote, “competition-oriented mandate.” And I think that was bad for Darpa. And the internet, which arose under Arpa — its hard to think of innovations of similar magnitudes that then occurred in then-Darpas subsequent, say, two decades.
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If you take, say, U.S. science in general, the war — the Second World War — to some extent, the first, but much more so the second — precipitated an enormous centralization of U.S. science in its aftermath. Because we really marshaled together all of the — or a significant fraction of the scientific capacity of the U.S. in service of the war effort.
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<p class="css-at9mc1 evys1bk0">
For, example the 50 percent overhead, the fraction of government grants that goes to universities — that was chosen in the early days of the coordination of the war effort, and has now become a kind of a pillar of academic and research funding in the U.S. And in the aftermath of the war, we sort have this question of OK, weve kind of pulled everything together. Now, what do we do?
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<p class="css-at9mc1 evys1bk0">
And that became, in various ways, the N.I.H. and the N.S.F. and so on. I mean, the N.I.H. predated it, but the growth of the N.I.H. really occurred after the war. And the federal government, shortly thereafter, for the first time, became the majority funder of US science. And all that centralization — and I mean, you pointed out the benefits of variety and of experimentation and of heterogeneity, and having some degree of institutional and structural diversity and so on, I totally agree with all of that.
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<p class="css-at9mc1 evys1bk0">
And I think all of that was very meaningfully curtailed by, again, the aftershocks of some of the threats that we faced during the war. And if you think about the things that were maybe happiest about having happened — the founding of the major new U.S. research universities in the latter parts of the 19th century or the revolution in health care and kind of medical practice that first happened at Johns Hopkins, and then kind of codified in the Flexner Report, or the great industrial research labs of Bell and Park and so on — or excuse me — Xerox — they didnt obviously come from a place of fear or a threat.
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<p class="css-at9mc1 evys1bk0">
They came from a place of hope and optimism and opportunity. And maybe there are some inventions that youre more likely to get to from some of these external pressures. But yeah, if you gave me a dial, and I can kind of turn up or down the threat or fear index of society, its not super obvious to me that one would want to turn it up if what one cared about was the aggregate rate of progress.
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<p class="css-at9mc1 evys1bk0">
EZRA KLEIN: Thats a good bridge, I think, to the question of institutions. And I take one of the main concerns of yours, of progress studies, as being around institutional slowdown. You have this idea that we dont meta-maintain institutions very well.
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They start in one place, and then over time, they crust over, and we dont really know what to do with that. Give me a little bit of your thinking there.
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PATRICK COLLISON: I think institutions, the cultures they instill and act as kind of coordination points and training sites for — those of enormous consequence — I think much of the success of the U.S. and of various other Western countries has, in substantial part, been attributable to successful institutions. Most people would accept, I think, that there is, to some extent, consistent trends that tend to happen with institutions through time.
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<p class="css-at9mc1 evys1bk0">
Just maybe most basically, the problem that gives rise to an institution in the first place is probably a pretty real and significant problem. No one would have taken the time to found the institution if it wasnt. And there can be some degree of drift there, where we dont necessarily decommission the institution once the problem has subsided or abated.
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<p class="css-at9mc1 evys1bk0">
And then, you tend to attract a certain kind of person in the early days of an institution — people who are slightly less status and reputation and procedure-oriented, because a new institution almost never has that. And then, through time, the sort of collective or the mission-oriented incentives of the institution can kind of drift somewhat from the individual incentives that particular people are subject to.
</p>
<p class="css-at9mc1 evys1bk0">
I think all this stuff exists. And the thing that I observe, or that I just find myself thinking about is, weve had eras of institution formation in the U.S. It has not been kind of a constant rate through time. And the New Deal maybe, and say, the 30 years afterwards, and the Great Society — we bookend it with those start and endpoints.
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<p class="css-at9mc1 evys1bk0">
That was a period of tremendously active institution construction and formation in the U.S., Darpa being — or Arpa originally being a good example, and indeed, NASA. And I guess I find myself wondering, one, if we didnt have any of these institutions — and Im not saying we should get rid of them. But if we didnt have them, what institutions would we found today, first, and how high in the list would NASA be, for example?
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And then, secondly, in as much as we accept that some of these institutional dynamics exist, like the fact that sclerosis as an emergent property arises, what do we do about that? And lots of people have told us its pretty — doesnt need a lot of teasing apart to see it as one compares NASA and SpaceX and the respective budgets, and the respective achievements, and so forth, I think its hard to not at least wonder about their respective efficiencies.
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And say, if society could only have SpaceX or NASA, which one would we choose, and what should we conclude from that, and to what extent do those phenomena generalize elsewhere? I dont have answers to these questions. But I find that in the political discourse — not that anybody is celebrating that, but in the discourse, its very easy to get, I think, very wrapped up in questions of optimal funding levels, and should this number be 10 percent or 50 percent or higher or whatever, whereas to me, a lot of our satisfaction with the outcomes seems to hinge on deeper questions about the nature of the institution.
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<p class="css-at9mc1 evys1bk0">
I dont know that the problem or benefit, or anything good or bad about NASA is attributable to the budget, per se. It seems more, kind of, resonant in some of these deeper cultural questions. And then, in the recent pandemic, or in the — I dont know. I was going to say, ongoing pandemic. But I guess as of two days ago, with the Presidents verdict, it is now over.
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EZRA KLEIN: Its over. Congratulations, everybody.
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<p class="css-at9mc1 evys1bk0">
PATRICK COLLISON: Exactly. But anyway, I think that was maybe a vivid demonstration of many of these dynamics, where I dont know this any of the story about the institutional response to the pandemic should be primarily one of funding. I think its much more about the dispositions and the attitudes and the cultural biases of entities like the N.I.H. and the F.D.A. and the C.D.C.
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EZRA KLEIN: I find the NASA SpaceX example an interesting and provocative one. Because on the one hand, I think what youre saying is completely true. And where a lot of the NASA programs and projects have gone in recent decades, is just — its sad. Its just a sad story.
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<p class="css-at9mc1 evys1bk0">
And on the other hand, the idea that you — the thought experiment of choosing between NASA and SpaceX — the thing that it immediately asks is, well, you cant. Because without NASA, there is no SpaceX. And one way the private sector handles a lot of these questions — I mean, Im always struck by how much of the way biotech research works is that big pharmaceutical companies acquire small biotech firms that have made a breakthrough or have come up with a very promising candidate. This is kind of an accepted thing that the big companies — they do a fair amount of research, but a major, major innovation transmission there is small groups do more, quicker, and theyre just going to buy them. And the NASA SpaceX example has a little bit of that dynamic to it, although with a different mechanism of financing. And I dont know. I wonder if there arent deeper lessons there.
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PATRICK COLLISON: Yeah, I dont mean here in the NASA example — like, I dont think reducing it to a simple binary of this-or-that is correct. Its more, what should we make of the differences in these two organizations? And given those observations or beliefs, what do we then think an efficient outcome might look like?
</p>
<p class="css-at9mc1 evys1bk0">
And do we think that where we are today — this prevailing status quo — is optimal? Or are there other things we can do better? And maybe an important thing to say within all of this is, to the extent that these are all kind of inevitably determined outcomes, maybe it doesnt really matter if we think things would be better or worse.
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<p class="css-at9mc1 evys1bk0">
Were going to end up in the same place, regardless. But I think for all of these, its super contingent. And various aspects of both funding decisions and, kind of, the precepts and methodologies of the N.I.H., how we design I.P. law, how we regulate and require and run clinical trials — there are tons of individual contingent decisions that we kind of have collectively made that give rise to the biotech and to the pharma ecosystem.
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<p class="css-at9mc1 evys1bk0">
And certainly, in the case of space, you know, like, it doesnt have to be this way other. Universes, no pun intended, are possible. I think perhaps the thing that people underappreciated with science in the U.S. is, it has been very different in the not-too-distant past.
</p>
<p class="css-at9mc1 evys1bk0">
Peer review is a relatively recent invention. Modern journals are a relatively recent invention. As I mentioned, the federal government being the primary funder of basic research is a relatively recent invention.
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<p class="css-at9mc1 evys1bk0">
And molecular biology was, in significant part, a thesis by Warren Weaver at the Rockefeller Foundation. Theres a thing here, and we should aggressively pursue it. But importantly, it was not — it required an institution, an organization, that was not part of the standard apparatus, for want of a better term.
</p>
<p class="css-at9mc1 evys1bk0">
And the Broad Institute, over the last 25 years, has been enormously successful in the field of genomics and functional genomics and CRISPR, et cetera. And the Broad Institute is itself a kind of structural innovation, breaking somewhat from the more traditional prevailing university model. And so I think the fact that so many of our successes are associated with some degree of structural and institutional change should be somewhat thought-provoking for us.
</p>
<p class="css-at9mc1 evys1bk0">
EZRA KLEIN: Youve been trying to work in the space of institution-building here, too. I want to talk about Fast Grants and about Arc a little bit. So lets begin with Fast Grants. What is it, and what has it taught you?
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<p class="css-at9mc1 evys1bk0">
PATRICK COLLISON: Well, its mostly “what was it.” In the early days of the pandemic — well, I should preface all of this by saying — well, Ill reaffirm my preface that I dont know, to every question. But more importantly here, I will say, my now-wife is herself a scientist. Weve known each other since we were teenagers. We spend a lot of time talking about science in various forms.
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EZRA KLEIN: You met — am I allowed to say this? You met at a science competition.
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PATRICK COLLISON: That is true. We met at a science competition, 100 teenagers, and —
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<p class="css-at9mc1 evys1bk0">
EZRA KLEIN: And she beat you.
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<p class="css-at9mc1 evys1bk0">
PATRICK COLLISON: And yes. I was the runner-up, and she was the winner. I had created a programming language and a new dialect of lisp, and she had created a new treatment for urinary tract infections. And so I really dont envy the judges for having to figure out what framework one should use to make all these comparisons and lots of other people.
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EZRA KLEIN: You sound a little bitter, man.
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<p class="css-at9mc1 evys1bk0">
PATRICK COLLISON: [CHUCKLES] I was gonna say, but no, we can all agree this the correct outcomes ensued. Anyway, so we were living together in March of 2020, holed up. And a number of her friends and colleagues were unsurprisingly with, I guess, a large fraction of all biology scientists, were trying to urgently repurpose their work to figure out, well, could they do something that would be somehow benefit to accelerating the end of the pandemic?
</p>
<p class="css-at9mc1 evys1bk0">
And by early April, so a couple of weeks into lockdown, when it was becoming apparent and striking to us, which was it is difficult for these people to get funding for their work. And that might sound a bit, kind of, surprising, because you think, well, dont they have some degree of money already? And couldnt they just go and just spend that?
</p>
<p class="css-at9mc1 evys1bk0">
But there are, obviously, significant rules around and restrictions around that which one can do with ones grant money. This is money provided by the government for a purpose. And so its not like you can go and readily spend it on something totally unrelated.
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<p class="css-at9mc1 evys1bk0">
And the money is administered by the university, and so you have to go through their proper procurement processes. Point is, lots of restrictions on scientists pecuniary ability to suddenly repurpose the research agendas. And we kind of thought, well — we assume maybe in the early weeks, that presumably various bodies — I dont know who — some kind of amorphous other, some combination of C.D.C., F.D.A., N.I.H., philanthropies — whatever.
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<p class="css-at9mc1 evys1bk0">
Somebody will come along and just give these scientists the obvious money that society clearly should, so they can go, and they can pursue these programs. Didnt seem to be happening. I mean, to be fair, I dont want to give us too much credit.
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Various people were doing things right off the bat in various different places, but we just personally knew of lots of specific examples of really good scientists who were unable to make progress of their work to the extent that they would like. So we tried to set up what we thought would be a pretty small initiative, and called Fast Grants.
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<p class="css-at9mc1 evys1bk0">
The basic idea would be, you send us some kind of proposal. And initially, within 48 hours, you would get a funding decision and either receive money or not. We started out with a pretty small amount of money.
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<p class="css-at9mc1 evys1bk0">
The initial donors — we were among them, but there were a number — contributed, best I recall, about $10 million. Launched the website early April 2020. Quickly inundated with, I think, four and a half thousand applications, which, given our promised 48-hour turnaround, was somewhat challenging.
</p>
<p class="css-at9mc1 evys1bk0">
I should say this was myself. This was Silvana, my wife, and this was Tyler Cohen. So we had an immediate question as to, how do we actually run a philanthropic endeavor? And how do we stand it up in very short order? And he, through Mercatus and through Emergent Ventures, had some experience of very efficient and somewhat-scaled grant-giving.
</p>
<p class="css-at9mc1 evys1bk0">
And so the three of us worked together to put it together over the course of a week or so. We proceeded over the course of, roughly speaking, the next year, slightly more, to make about 200 grants, eventually dispersing almost — or slightly over, actually — $50 million in total, to universities around the world, though primarily in the U.S.
</p>
<p class="css-at9mc1 evys1bk0">
And you ask, kind of, what did we learn? A big surprise was how slowly other parts of the establishment mobilized. And various of the projects we funded or the labs we funded and so on — theyve gone on to now do — none of them were directly implicated in the vaccine research project that ended up yielding so much fruit. So again, I dont want to give Fast Grants too much credit. Eventually, the thing that really mattered, we had nothing to do with.
</p>
<p class="css-at9mc1 evys1bk0">
But versus the projects, things like Saliva Direct, which was in the summer an early discovery that saliva tests work basically as well as the nasopharyngeal swabs we were all being subject to, or various discoveries around possible therapeutics, some of which are — still continue to go through clinical trials, and may still turn out to matter to a significant extent. And that 500 people are still dying in the U.S. per day from Covid, and — despite the existence of the vaccines and so on.
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<p class="css-at9mc1 evys1bk0">
So anyway, various discoveries ensued that I think will prove to be important. And the second thing we learned, which is not really related to Covid or the pandemic, but has certainly been significant for us, is — it just got us thinking more deeply and broadly about the questions of, how do scientists choose what to do? And what are the constraints theyre subject to as a practical and applied matter?
</p>
<p class="css-at9mc1 evys1bk0">
And this gets back to all this discussion about both culture and institutions. And towards the end of Fast grants, we ran a survey of the grant recipients. And these are essentially all people who dont normally — certainly dont normally work on Covid. Covid didnt exist.
</p>
<p class="css-at9mc1 evys1bk0">
But they dont even normally work on viruses, for the most part. These are basically kind of broadly drawn as a cross section across biology. And we just asked them, as a general matter in your regular research, if you could spend your grant money however you want, how much would you change your research agenda?
</p>
<p class="css-at9mc1 evys1bk0">
So not an increase in the funding level, which tends to be what we discuss in as much as were discussing science policy across society. But much more specifically and narrowly, if you had complete autonomy in how you spend whatever grant money youre getting, how much of your research agenda would change? And our intuition was that maybe a third of people would like to be doing something meaningfully different to what they actually are.
</p>
<p class="css-at9mc1 evys1bk0">
But of these scientists, and these are really good scientists, four out of five told us that they would change their research agendas, quote, “a lot.” We gave them three options. Not much, or not at all, a little, and then a lot. Four out of five chose the maximum option on our survey. So I just find this incredibly thought-provoking.
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<p class="css-at9mc1 evys1bk0">
Basically, we seem to be in a situation where most of our top scientists arent doing what they think would be best for them to do. And we could say, no, our various committees and governing bodies and decision-making apparatus and so on, they know better. And Im not saying it would be completely unreasonable for one to maintain that. But that would seem to be a very central question about the construction of our scientific apparatus. And I think that should give us some pause.
</p>
<p class="css-at9mc1 evys1bk0">
EZRA KLEIN: There are a couple things there. One is that it is a consistent observation I have learning about new areas that there is a way were taught the thing works, or people think the thing works, and theres this huge middle layer. Right? So in politics, which I know very well, and legislation, you have the “Schoolhouse Rock” version of how a bill becomes a law. And then its, like, a filibuster is how a bill becomes a law or does not become a law.
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We were talking about drug innovation earlier. I think the folk way people think it works is we make a discovery about a drug, and then, like, we make a drug out of it after some tests. But you talk to people who work on pharmaceuticals and just clinical trials.
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<p class="css-at9mc1 evys1bk0">
And in science — I think if you had asked me as a high schooler, had some science classes, Id have told you something about the scientific method. And then you talk to a scientist, and its grants. Like, grants are how science works. Grants are the middle layer between — you are a scientist, and you can do some science. And grants are how the N.S.F. and the N.I.H. work. Theyre how a lot of the universities work. Theres fund-raising.
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<p class="css-at9mc1 evys1bk0">
I mean, there are different ways that it happens. To make the question of “Are we doing science well?” a little bit more precise, I think one version of that question is, “Are we doing grants well?” And I think that question is more tractable. People dont feel as defensive about it.
</p>
<p class="css-at9mc1 evys1bk0">
But Ive talked to a lot of scientists in the course of my work. Ive covered health care for my entire career. And I dont know any who think were doing grants well. I dont know any who will not complain to you for hours.
</p>
<p class="css-at9mc1 evys1bk0">
And they may be wrong. And I do want to note — because they also just have somewhat different incentives. I mean, I was noting earlier, and I think its very real. The government, particularly when it gives out grants, needs to worry about the reputational cost of the grant. If the grant goes wrong, if not enough of the grants pay out into useful research. If Rand Paul can stand up in Senate and make what you did sounds silly, these things really end up mattering. And so you get a process that is optimizing for a lot of different things.
</p>
<p class="css-at9mc1 evys1bk0">
But the question of whether or not we do grants well ends up being really, really, really important in every country that does major capital science that I know of, and is just not the main question for a bunch of different reasons we ask.
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<p class="css-at9mc1 evys1bk0">
PATRICK COLLISON: Yeah. Another question we asked in our survey was how much time they spend on the grants. I think to some extent, this is perhaps — at least, of those whove spent some amount of time interacting with scientists, kind of more broadly known than perhaps the finding with respect to how they do — or the degree to which they can choose what they work on. But we found that — or they reported to us that they spend on the order of 40 percent of their time on grant administration.
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<p class="css-at9mc1 evys1bk0">
And even if one were to maintain that the decision-making apparatus around what scientists do is somehow efficient, I think it is a very tenuous position to also try to argue that 40 percent of the best scientists time is optimally allocated towards grant applications, authorship and administration. And were not talking about an inconsequential 40 percent here.
</p>
<p class="css-at9mc1 evys1bk0">
I mean, this is 40 percent of the time of this super-elite 10,000, 100,000, whatever it is, some relatively finite number of people. And weve chosen to take and to redeploy almost half of their time in service of technocratic, bureaucratic undertaking. And getting back again to this point about people perhaps falsely assuming that things have been more inter-temporally consistent than they have, that percentage has increased very substantially over the last couple of decades as the overall edifice of science has grown, and as the kind of acceptance rates and the various thresholds for various grants has become more exacting.
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<p class="css-at9mc1 evys1bk0">
EZRA KLEIN: How we allocate peoples time is really important. But also, just how we allocate talent is really important. And it brings me to something you said that I wanted to ask you about. This was in response to a question about whether big tech companies are hogging all the talent in society.
</p>
<p class="css-at9mc1 evys1bk0">
And you said, quote, “I dont think that the ambitious upstarts who go into high speed rail in America, anyway, are going to have a great time or have much success in convincing their friends to follow them. And I suspect that for various reasons, too many domains look somewhat like high speed rail.” And so you go on to say that theres a view that the internet is a frontier of last resort, and that you dont think thats totally wrong.
</p>
<p class="css-at9mc1 evys1bk0">
So tell me about that. Tell me about the idea of the internet as a frontier of last resort. But behind that, this idea that other frontiers where talented people might want to go and make their mark on society have closed.
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<p class="css-at9mc1 evys1bk0">
PATRICK COLLISON: Youre familiar with and youve probably written about the Stephen Teles idea of kludgeocracy. And I kind of like the term “kludgeocracy,” because rather than making some of the inhibitions that people might encounter in pursuing something like high speed rail, rather than casting those as being deliberate, the valence is more that its this kind of emergent, inadvertent and kind of complicated phenomena that nobody perhaps particularly wants or chose.
</p>
<p class="css-at9mc1 evys1bk0">
And I think the case of Californias high speed rail is quite striking, where — youve written about this and kind of similar projects and the New York subway expansion and so on. And congestion pricing and so on. But its striking where its not actually obviously a question of first order political will.
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<p class="css-at9mc1 evys1bk0">
Like, were willing to fund the high speed rail in California. Were clearly willing to invest in building the subway expansion in New York. But somehow, somewhere between that first order decision and desire and our actual ability to kind of instantiate it, something really goes wrong.
</p>
<p class="css-at9mc1 evys1bk0">
And you contrast that with stories of — in the case of, say, California, Henry Kaiser and these various other early part of the 20th century operators in the physical realm. And for a variety of reasons, but mostly prosaic state and county-level complications and things that would extend the time horizon of ones project, it has simply become meaningfully less-appealing for those people to undertake these initiatives. I mean, Foster City, not too far from where we are now, thats named after the eponymous Mr. Foster.
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<p class="css-at9mc1 evys1bk0">
He was a developer. He decided, well, with reclaimed wetlands, Im going to build a city. California is growing quickly. The Bay Area is a — kind of propitious and will be a long-term successful area. And I think this place simply needs more housing.
</p>
<p class="css-at9mc1 evys1bk0">
And he, with that kind of founder energy, was able to give birth and rise to the city that now bears his name. I havent met anybody pitching me on a similar city on the shores of the Bay in the last couple of years. But I would imagine that were one to adopt that ambition today and to propose that maybe the San Jose Marsh wetlands should themselves be an expansion of San Jose, I dont think one would get very far.
</p>
<p class="css-at9mc1 evys1bk0">
And in fact, even for much more sort of limited things, like additional runways or runway expansions at S.F.O., even they have now been stymied for decades at this point. That ability to translate that into something enunciated has dissipated and deteriorated. And then I think the kind of individual version is, and if I want to be that heroic solar farm entrepreneur or railway magnate, that my practical ability to do so has been meaningfully curtailed.
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<p class="css-at9mc1 evys1bk0">
EZRA KLEIN: Yeah. I mean, thats what Im getting at here a little bit, which is talent really matters for a society. Where the most talented people go really matters for society. And a lot of those people want to go somewhere where they can have a really big effect.
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<p class="css-at9mc1 evys1bk0">
I think theres been a huge rush to digital land because you can build on digital land. You can build quickly. I mean, its interesting to some of the dynamics were talking about, the temporal dynamics were talking about, that you see this dynamic even within the tech world.
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There was a while where it was really exciting to go join Facebook, go join Google, go join one of the big companies. Because you could do so much. And thats still, to some degree, true. But they got really big.
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<p class="css-at9mc1 evys1bk0">
And so crypto got — whatever you think of crypto, one thing that is exciting about it to people is the idea that its open land. That you can go in there and have a really big effect on it. Build something new just with a couple of friends that might change the whole direction of the field.
</p>
<p class="css-at9mc1 evys1bk0">
And on some level, its always going to be harder for, say, putting high speed rail through the middle of California. Right? I mean, just building things in the world is just going to be tougher.
</p>
<p class="css-at9mc1 evys1bk0">
But on the other hand, if you make building things in the world too hard, if you make grants too difficult — if you — I know a lot of doctors who their advice to young people is dont become a doctor. And it always breaks my heart a little bit. We need really great people to be doctors.
</p>
<p class="css-at9mc1 evys1bk0">
And their point is not, dont go heal sick people. Their point is, being a doctor is too hard now. The amount of time you spend dealing with insurance agencies and malpractice insurance and boards, and this and that, its just too much administration.
</p>
<p class="css-at9mc1 evys1bk0">
When industries become very complicated to operate in, you want to select for people who are good at operating complicated industries, which may be different than the people who are good at moving really fast and changing things dramatically. But two, you kind of subtly bias where different kinds of people in your society go. I think in China, if you want to change a lot, you still probably go into infrastructure construction, among other things. Right?
</p>
<p class="css-at9mc1 evys1bk0">
The idea that you might be a genius rail mind, in China, thats great. Theres probably a lot of rail you can make. Thats not true here. And the point is not to make too much of the rail example, but to make a lot of the idea that talent flows towards where it can have an effect and people can live the kinds of heroic lives they want to lead. And if we have subtly pushed a lot of people into maybe not the right — not the socially optimal directions, that over time will have a pretty big effect on a society.
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PATRICK COLLISON: I think a constant is that some number of ambitious young people will want to do something, as you say, heroic. And yeah, I think maybe two things have changed. For one, for whatever reason, our predisposition to putting those people in positions of authority has diminished. And then secondly, even if placed, their ability to actually execute, again for various reasons, has been attenuated.
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<p class="css-at9mc1 evys1bk0">
Ive been reading about the university founders and presidents and those associated with some of the great US research institutions. And one thing that is striking is how many of them were so young when placed in those positions of authority. You know, Daniel Coit Gilman at Johns Hopkins, or William Rainey Harper at the University of Chicago. I think he was 32 when he was appointed president of the University of Chicago. Even in the recent past.
</p>
<p class="css-at9mc1 evys1bk0">
So my dad was in the first year of the University of Limerick in Ireland. Or at the time, it was called N.I.H.E. It kind of acquired university status later in its life. And the Irish guy who founded it and was really the dynamo behind it, I think he was 29 when he was put in charge of that project.
</p>
<p class="css-at9mc1 evys1bk0">
And I think it was in 1970 or 71 that he was charged with this mission. But as recently as 1970 in Ireland, we were willing to put a 29-year-old — I mean, thats a person meaningfully younger than me in charge of the project of overseeing the creation of a major new research institution. And I dont know that I have compelling or confident observations to offer in terms of the etiology underlying these changes. But I think the changes themselves are important, or at least we should assume theyre important if we come from a place of humility, where this is what has worked in the past. Enabling these ambitious young people who are willing to contemplate spending multiple decades in pursuit of some ambitious and idiosyncratic vision.
</p>
<p class="css-at9mc1 evys1bk0">
And maybe were more enlightened now. Maybe we figured out how to get all the same innovation and all the same breakthroughs without unleashing that force. But I guess my starting point, at least, would be, well, we should — before getting super confident in that or before really being deliberate about it, I think we should give some kind of credit and credence to the prescription and the methodology thats worked heretofore.
</p>
<p class="css-at9mc1 evys1bk0">
EZRA KLEIN: And before books, let me end on this. Weve talked a lot about scientific slowdown, about technological slowdown. But lets say in the next 15-year time frame, what are the three technological or scientific possibilities youre most excited by? If in 20 — I guess itd be 2037, were having a conversation about how dumb this conversation was because it was right on the cusp of so much incredible stuff happening, what do you think is likely to be on that list?
</p>
<p class="css-at9mc1 evys1bk0">
PATRICK COLLISON: I dont know that Ive super non-consensus answers. I think that there are fundamental a priori reasons to believe that the rate of progress in biology could increase substantially over the years, and to your question, kind of decades to come. So if in 2037 we are enormously impressed and struck by the discontinuity there, that would not shock me.
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<p class="css-at9mc1 evys1bk0">
Clearly, over the past couple of years, theres been acceleration in progress in A.I. And kind of far for me to try to point estimate for kind of where that is in 2037. But I would be surprised if that is not somewhere on that list.
</p>
<p class="css-at9mc1 evys1bk0">
And then I think theres something about education in the broadest sense that feels to me like a very significant, and hopefully very positive change happening in the world right now. Maybe best embodied by YouTube. But also by Twitter and by blogs and Substacks and even Zoom and kind of the growing ease of being in some kind of cultural proximity to people one aspires to emulating, or following in the footsteps of, or otherwise kind of being more like.
</p>
<p class="css-at9mc1 evys1bk0">
And to the extent that one believes my story about the significance of sociology, and culture, and mentorship, and the kind of delicate transmission of tacit knowledge, it has until very recently only been possible for that to happen to a meaningful extent through physical co-location. And the fact that weve now thrown open those doors to such an extent feels to me like a really compelling and plausibly transformative change. And if it were the case in 2037 that we have multiplied by 20 the number of people who can — who have the initial mental models and understanding to become successful entrepreneurs, or successful scientists, or successful writers, or successful in whatever one might choose ones domain to be, again, I think that would not be shocking. And I think its a pretty hopeful fact about the world.
</p>
<p class="css-at9mc1 evys1bk0">
EZRA KLEIN: And then always our final question. What are the three books youd recommend to the audience?
</p>
<p class="css-at9mc1 evys1bk0">
PATRICK COLLISON: Well, Im right now reading “Revolution and Empire,” which is a book about Edmund Burke. And it is just fabulous. I very highly recommend it.
</p>
<p class="css-at9mc1 evys1bk0">
Edmund Burke, Irelands foremost political philosopher. And Im embarrassed to say that I have known less about him than I feel like I ought to have. So I recommend that very highly.
</p>
<p class="css-at9mc1 evys1bk0">
And the autobiography by Warren Weaver, who I mentioned, at Rockefeller. I cant remember if its called “Scene of Change” or “Scene of the Action.” But its Warren Weavers autobiography.
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<p class="css-at9mc1 evys1bk0">
Thats not a great book in the sense that you dont read it — you dont find it to be a vivid, compelling page-turner. And your mind is not blown on every page. But I find myself thinking back to it quite a lot and having various parts of it sort of ricochet to my mind.
</p>
<p class="css-at9mc1 evys1bk0">
And then it all depends on what people are interested in and all the rest. And you should read the things you like. But I have on my desk at home right now “A Widening Sphere,” which is a history of M.I.T. And I was re-reading it recently. And my —
</p>
<p class="css-at9mc1 evys1bk0">
EZRA KLEIN: Who doesnt re-read the histories of M.I.T.?
</p>
<p class="css-at9mc1 evys1bk0">
PATRICK COLLISON: [LAUGHS] Well, William Barton Rogers, the founder, was the son of an Irishman, and started M.I.T. substantially with his brother. And I find it very inspiring, I guess back to what we were saying earlier, how motivated he was and they were by a kind of broad-based desire for societal betterment. Like, M.I.T. didnt inadvertently end up being a significant contribution to American prosperity and ingenuity and welfare. He was really immersed in that milieu.
</p>
<p class="css-at9mc1 evys1bk0">
He paid a lot of attention to some of the cultural dynamics we were describing in England, and the Darwins. And the early writing on M.I.T., if you go and just read the first two pages of the founding manifesto, it wasnt utopian in some kind of implausibly lofty sense. But it was somebody who knew they werent founding a run of the mill nth technical college.
</p>
<p class="css-at9mc1 evys1bk0">
And I feel like its easy to get cynical always. Its easy to assume that the things that really worked out worked out through happenstance, as opposed to optimism and ambition. But yeah, I find the history of MIT to be a kind of inspiring reminder that sometimes these implausible, lofty, ambitious, long-term initiatives can work out much better than one would hope.
</p>
<p class="css-at9mc1 evys1bk0">
[MUSIC PLAYING]
</p>
<p class="css-at9mc1 evys1bk0">
EZRA KLEIN: Patrick Collison, thank you very much.
</p>
<p class="css-at9mc1 evys1bk0">
PATRICK COLLISON: Thanks for having me.
</p>
<p class="css-at9mc1 evys1bk0">
[MUSIC PLAYING]
</p>
<p class="css-at9mc1 evys1bk0">
EZRA KLEIN: “The Ezra Klein Show” is produced by Annie Galvin and Rogé Karma. Fact-checking by Michelle Harris, Mary Marge Locker and Kate Sinclair. Original music by Isaac Jones.
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recommendations.","image":{"id":"SW1hZ2U6bnl0Oi8vaW1hZ2UvN2M3NTQ0NjktMjQ5Zi01YjllLWFlODEtMzNlNjk5NDk3ZjY5","crops":[{"renditions":[{"url":"https:\u002F\u002Fstatic01.nyt.com\u002Fimages\u002F2021\u002F01\u002F12\u002Fpodcasts\u002Fezra-klein-album-art\u002Fezra-klein-album-art-articleInline-v2.jpg","name":"articleInline","width":190,"height":190,"__typename":"ImageRendition"},{"url":"https:\u002F\u002Fstatic01.nyt.com\u002Fimages\u002F2021\u002F01\u002F12\u002Fpodcasts\u002Fezra-klein-album-art\u002Fezra-klein-album-art-hpSmall-v2.jpg","name":"hpSmall","width":163,"height":163,"__typename":"ImageRendition"},{"url":"https:\u002F\u002Fstatic01.nyt.com\u002Fimages\u002F2021\u002F01\u002F12\u002Fpodcasts\u002Fezra-klein-album-art\u002Fezra-klein-album-art-blogSmallInline-v2.jpg","name":"blogSmallInline","width":151,"height":151,"__typename":"ImageRendition"},{"url":"https:\u002F\u002Fstatic01.nyt.com\u002Fimages\u002F2021\u002F01\u002F12\u002Fpodcasts\u002Fezra-klein-album-art\u002Fezra-klein-album-art-mediumFlexible177-v2.jpg","name":"mediumFlexible177","width":177,"height":177,"__typename":"ImageRendition"}],"__typename":"ImageCrop"}],"__typename":"Image"},"__typename":"AudioPodcastSeries","name":"Ezra-Klein-Show-Podcast"},"credit":"","audioTranscript":{"transcriptFragment":[{"text":"I'm Ezra Klein.","speaker":"EZRA KLEIN","timecode":{"start":4.975,"end":6.1,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"This is \"The Ezra Klein Show.\"","speaker":"EZRA KLEIN","timecode":{"start":6.1,"end":7.53,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"This is a great conversation today.","speaker":"EZRA KLEIN","timecode":{"start":22.85,"end":24.71,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But it's a tricky one to introduce, because the guest I have --","speaker":"EZRA KLEIN","timecode":{"start":24.71,"end":29.77,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I'm not having him on for the thing he's best known for.","speaker":"EZRA KLEIN","timecode":{"start":29.77,"end":33.22,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So Patrick Collison -- by day, co-founder and C.E.O. of the multibillion-dollar payments company, Stripe; by night, by weekend, I think, one of the most important thinkers now in Silicon Valley -- certainly, one of the most quietly influential,","speaker":"EZRA KLEIN","timecode":{"start":33.22,"end":47.29,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"someone who is forging and traversing an intellectual path that a lot of other people are now following.","speaker":"EZRA KLEIN","timecode":{"start":47.29,"end":53.59,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And it's this second incarnation and role that I'm really interviewing him in today --","speaker":"EZRA KLEIN","timecode":{"start":53.6,"end":59.26,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"the soft power side, I guess, of Patrick Collison.","speaker":"EZRA KLEIN","timecode":{"start":59.26,"end":63.32,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Collison's work here centers around this question of progress.","speaker":"EZRA KLEIN","timecode":{"start":63.32,"end":66.89,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"The argument is that human progress is much more precious and rare and fragile than we realize.","speaker":"EZRA KLEIN","timecode":{"start":66.89,"end":72.2,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"We maybe take it for granted.","speaker":"EZRA KLEIN","timecode":{"start":72.21,"end":73.77,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"We live in this time when things have been changing, atop decades and decades, even centuries and centuries, even millennia now, when things have kept changing.","speaker":"EZRA KLEIN","timecode":{"start":73.77,"end":82.62,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But for most of human history, that was not true.","speaker":"EZRA KLEIN","timecode":{"start":82.62,"end":85.26,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"It was not true.","speaker":"EZRA KLEIN","timecode":{"start":85.26,"end":87.09,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"There just was no market rapid advance in human living standards.","speaker":"EZRA KLEIN","timecode":{"start":87.1,"end":90.89,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"It's only in the past 10,000 years, and then practically in the past few hundred -- just an eye-blink in the time human beings have been on Earth --","speaker":"EZRA KLEIN","timecode":{"start":90.89,"end":99.05,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"that things kept changing, usually for the better.","speaker":"EZRA KLEIN","timecode":{"start":99.05,"end":102.69,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And the question is, why?","speaker":"EZRA KLEIN","timecode":{"start":102.69,"end":104.24,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And Collison's particular meta question is, given the clear fragility of forward motion here, given how rare it has proven to be --","speaker":"EZRA KLEIN","timecode":{"start":104.25,"end":113.73,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"and so how easy it might be to lose -- why isn't the question of the conditions of progress more central?","speaker":"EZRA KLEIN","timecode":{"start":113.73,"end":119.54,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Why isn't the study of progress in a wide multidisciplinary way a more common and central discipline?","speaker":"EZRA KLEIN","timecode":{"start":119.54,"end":129.46,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Collison has written a few influential essays here, with the economist Tyler Cowen.","speaker":"EZRA KLEIN","timecode":{"start":129.47,"end":133.21,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"He called for the inauguration of a discipline -- they call it progress studies -- and that now has people studying it.","speaker":"EZRA KLEIN","timecode":{"start":133.21,"end":138.89,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"There's people creating journals for it, creating syllabi and podcasts and books around the topic.","speaker":"EZRA KLEIN","timecode":{"start":138.89,"end":144.23,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"It's one of the more singularly successful calls for a research direction I have seen.","speaker":"EZRA KLEIN","timecode":{"start":144.23,"end":148.66,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Separately, in a piece co-authored with the scientist, Michael Nielsen, Collison and Nielsen argued that, though it is hard to measure, it seems like the rate of scientific progress is slowing down,","speaker":"EZRA KLEIN","timecode":{"start":148.67,"end":158.89,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"and that's particularly true if you account for how much more we're putting into science, in terms of money, of people, of time and technology.","speaker":"EZRA KLEIN","timecode":{"start":158.89,"end":166.75,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Now, these ideas are not original to Collison.","speaker":"EZRA KLEIN","timecode":{"start":166.76,"end":169.97,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"The point is not that nobody studied human progress before this or worried about the pace of scientific research.","speaker":"EZRA KLEIN","timecode":{"start":169.97,"end":175.18,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"He wouldn't claim that.","speaker":"EZRA KLEIN","timecode":{"start":175.18,"end":176.14,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"It wouldn't be true.","speaker":"EZRA KLEIN","timecode":{"start":176.14,"end":177.31,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But he is playing a distinctive role in their framing and their popularization, and in creating and funding a community around them.","speaker":"EZRA KLEIN","timecode":{"start":177.31,"end":185.35,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And what I see in my travels here is that it is working.","speaker":"EZRA KLEIN","timecode":{"start":185.36,"end":188.62,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Something is burbling here.","speaker":"EZRA KLEIN","timecode":{"start":188.62,"end":190.36,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But I can't find many big pieces where Collison really lays out his worldview.","speaker":"EZRA KLEIN","timecode":{"start":190.36,"end":194.06,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"There are a couple essays, tweets, interviews, but he's not been primarily writing this down.","speaker":"EZRA KLEIN","timecode":{"start":194.06,"end":198.37,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"What he has been doing is funding it through Fast Grants, which has been successful, but more than that, intellectually influential effort to show you can give out scientific grants quickly and with very little overhead,","speaker":"EZRA KLEIN","timecode":{"start":198.38,"end":209.23,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"through the Arc Institute, a big biotech organization he's creating to push a researcher-first approach to biotech, and through giving a bit of money, and a bit of time, and a bit of prestige, and a bit of networking to a lot of different projects that circle these questions.","speaker":"EZRA KLEIN","timecode":{"start":209.23,"end":223.75,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"He's got this funny quality of being nowhere in particular, but also somehow, almost everywhere, if you're interested in these questions.","speaker":"EZRA KLEIN","timecode":{"start":223.76,"end":232.46,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So what I wanted to do in this conversation was try to get as close as I could to the Patrick Collison worldview, the underlying theory of the case here that animates his thinking his funding, and the ways in which he's trying to nudge the culture he's a part of,","speaker":"EZRA KLEIN","timecode":{"start":232.46,"end":245.41,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"or the ways in which he's trying to actively create a culture he doesn't yet see.","speaker":"EZRA KLEIN","timecode":{"start":245.41,"end":249.82,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"As always, my email --","speaker":"EZRA KLEIN","timecode":{"start":249.83,"end":251.33,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"ezrakleinshow@nytimes.com.","speaker":"EZRA KLEIN","timecode":{"start":251.33,"end":252.97,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Patrick Collison, welcome to the show.","speaker":"EZRA KLEIN","timecode":{"start":257.219,"end":258.871,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Great to be back.","speaker":"PATRICK COLLISON","timecode":{"start":258.871,"end":260.329,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So you've made the argument that science -- all science -- is slowing down, that we're putting more money and more people into research, and we're getting less and less out of it.","speaker":"EZRA KLEIN","timecode":{"start":260.339,"end":269.43,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Tell me about that.","speaker":"EZRA KLEIN","timecode":{"start":269.43,"end":270.222,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Well, I want to separate two things.","speaker":"PATRICK COLLISON","timecode":{"start":270.222,"end":272.472,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"There's a question as to whether science in its totality is slowing down, in terms of the absolute returns from it.","speaker":"PATRICK COLLISON","timecode":{"start":272.472,"end":277.65,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I think that might be true.","speaker":"PATRICK COLLISON","timecode":{"start":277.65,"end":279.353,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"You can maybe divide up the first half of the 20th century and the second half and so on, and sort of try to compare one with the other.","speaker":"PATRICK COLLISON","timecode":{"start":279.353,"end":285.02,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And we had general relativity and quantum mechanics and various other major breakthroughs in the first half.","speaker":"PATRICK COLLISON","timecode":{"start":285.03,"end":290.007,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"You can ask the question of, well, did we have as many in the second half?","speaker":"PATRICK COLLISON","timecode":{"start":290.007,"end":293.09,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But in the second half, we did have the discovery of D.N.A. and molecular biology and lots of other things.","speaker":"PATRICK COLLISON","timecode":{"start":293.09,"end":297.548,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So I don't know that I would claim a total slowdown.","speaker":"PATRICK COLLISON","timecode":{"start":297.548,"end":299.84,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"The thing that I think is clearer and should be very concerning to us is, as you look at the number of scientists engaged in the pursuit of science, and if you look at the total amount that we're spending, and as you look at the total output, as coarsely measured by things like papers","speaker":"PATRICK COLLISON","timecode":{"start":299.84,"end":319.67,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"and number of journals, all of those metrics have grown by, depending on the number, let's say, between 20 and 100x between 1950 and, say, 2010.","speaker":"PATRICK COLLISON","timecode":{"start":319.67,"end":331.43,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And if you look at it on a per-capita basis, or a per-unit-of-work basis, now used to divide all those total outcomes by a factor of 50, and it seems like if you imagine yourself as the median scientist,","speaker":"PATRICK COLLISON","timecode":{"start":331.44,"end":346.19,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"you're meaningfully less likely to produce anything like as consequential a breakthrough as you would have, say, in 1920.","speaker":"PATRICK COLLISON","timecode":{"start":346.19,"end":353.58,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And so Michael Nielsen and I, in order to try to put slightly more rigor on that question -- we went and we surveyed a bunch of scientists across a number of universities in a number of different disciplines, and we presented them with different Nobel Prize-winning breakthroughs.","speaker":"PATRICK COLLISON","timecode":{"start":353.58,"end":370.83,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And we tried to compute an approximate ordering of their significance in the eyes of these scientists.","speaker":"PATRICK COLLISON","timecode":{"start":370.84,"end":378.02,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And the thing that would kind of have to be true -- for the per-capita impact, we remain in constant -- is we'd have to be discovering much more important things in the latter half of the 20th century in order to compensate for, to make it worthwhile,","speaker":"PATRICK COLLISON","timecode":{"start":378.02,"end":390.41,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"for us to be investing this 50-fold greater effort.","speaker":"PATRICK COLLISON","timecode":{"start":390.41,"end":393.44,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And we didn't find that.","speaker":"PATRICK COLLISON","timecode":{"start":393.45,"end":394.94,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"In physics, in the estimation of physicists, there was a kind of flat-to-declining trend.","speaker":"PATRICK COLLISON","timecode":{"start":394.94,"end":401.21,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"It's not super obvious which way it points, but in as much as there's a trend visible, it's probably slightly downwards.","speaker":"PATRICK COLLISON","timecode":{"start":401.21,"end":407.67,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And in other fields, it was maybe similarly equivocal, perhaps a slight increase, visible in some, but importantly, in no fields that it looked like we're on this crazy, exponentially improving trajectory, which is what you would have to have for this per-capita phenomenon to not be present.","speaker":"PATRICK COLLISON","timecode":{"start":407.67,"end":424.61,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I think that should be something we're interested in for multiple reasons.","speaker":"PATRICK COLLISON","timecode":{"start":424.61,"end":427.86,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"One, because presumably, as a society, we're interested in just how much more scientific progress and technological progress and so forth, how much more innovation is there going to be over the next 10 years or the next 50 years or the next century.","speaker":"PATRICK COLLISON","timecode":{"start":427.86,"end":439.49,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But also, because there's kind of two possibilities.","speaker":"PATRICK COLLISON","timecode":{"start":439.49,"end":442.5,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"One possibility is, fundamentally, we're running out of low-hanging fruit, and it's just going to be harder to do this stuff.","speaker":"PATRICK COLLISON","timecode":{"start":442.5,"end":449.93,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And in as much as we're setting investment or making investment decisions around to what degree should be pursuing the stuff, I guess it's important to know what we think the returns should be.","speaker":"PATRICK COLLISON","timecode":{"start":449.94,"end":461.27,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Or the other possibility is, somehow, we're doing it suboptimally.","speaker":"PATRICK COLLISON","timecode":{"start":461.27,"end":465.65,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Something changed, and we were pursuing this process of discovery more effectively in the past, and presumably, for inadvertent reasons, something went wrong, and now, we're just less efficient at it.","speaker":"PATRICK COLLISON","timecode":{"start":465.65,"end":477.05,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But either explanation -- and it doesn't necessarily have to be fully binary -- but either explanation is important, and either explanation, I think, has prescriptions for what we should do going forward.","speaker":"PATRICK COLLISON","timecode":{"start":477.06,"end":489.762,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Let me start with the low-hanging-fruit explanation, which I think is a more popular one.","speaker":"EZRA KLEIN","timecode":{"start":489.762,"end":493.97,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And you have -- in the piece you did on this with Michael Nielsen, the sad, but in the very academic way, very funny quote from the physicist Paul Dirac, who says of the 1920s, there was a time when, quote, \"Even second-rate physicists could make first-rate discoveries,\"","speaker":"EZRA KLEIN","timecode":{"start":493.97,"end":508.58,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"which I just kind of love.","speaker":"EZRA KLEIN","timecode":{"start":508.58,"end":510.44,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But the theory there is you can only make a lot of the big discoveries once.","speaker":"EZRA KLEIN","timecode":{"start":510.45,"end":514.309,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"You discover quantum mechanics once.","speaker":"EZRA KLEIN","timecode":{"start":514.309,"end":516.5,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"You discover the atom once.","speaker":"EZRA KLEIN","timecode":{"start":516.5,"end":518.48,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And most of them have just been made, so what you have now is more complicated, smaller, requires much larger teams of people, much more complicated experiments, with much more infrastructure.","speaker":"EZRA KLEIN","timecode":{"start":518.48,"end":529.94,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So we're just structurally in a period where it's going to get harder and harder and harder to make big gains.","speaker":"EZRA KLEIN","timecode":{"start":529.95,"end":537.9,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Do you believe that?","speaker":"EZRA KLEIN","timecode":{"start":537.9,"end":538.74,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I think it's possible, but even though it's intuitively compelling on some level, I'm not sure that it's true.","speaker":"PATRICK COLLISON","timecode":{"start":541.51,"end":548.91,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"It's probably true to at least some degree for some particular research direction, right?","speaker":"PATRICK COLLISON","timecode":{"start":548.91,"end":553.95,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"We go after discovering the various subatomic particles, and initially, without too much difficulty, we discover the electron or whatever.","speaker":"PATRICK COLLISON","timecode":{"start":553.95,"end":562.26,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And by the time we've discovered the nth quark, it's now gotten super hard, and even with ever-larger particle accelerators, we're not necessarily making breakthroughs of the same magnitude.","speaker":"PATRICK COLLISON","timecode":{"start":562.27,"end":571.347,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So I think it's pretty true for a given direction.","speaker":"PATRICK COLLISON","timecode":{"start":571.347,"end":573.43,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But obviously, the question is, well, to what degree is progress in any area opening up other directions, right?","speaker":"PATRICK COLLISON","timecode":{"start":573.43,"end":580.83,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And so I mean, you mentioned the Dirac quote and, say, physics in the early part of the 20th century.","speaker":"PATRICK COLLISON","timecode":{"start":580.84,"end":585.42,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Those discoveries opened up new techniques and investigation methodologies and so on, that then gave rise to molecular biology in the '50s, '60s and '70s.","speaker":"PATRICK COLLISON","timecode":{"start":585.42,"end":598.86,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And so there's kind of a combinatorial benefit, where discoveries over here or discoveries over there might unlock opportunities and major breakthroughs in areas that we could not have foreseen in advance.","speaker":"PATRICK COLLISON","timecode":{"start":598.86,"end":611.04,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"There are lots of, quote unquote, \"low-hanging-fruit discoveries\" made in computers and computer science in the '70s, '80s, and '90s.","speaker":"PATRICK COLLISON","timecode":{"start":611.05,"end":619.515,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Maybe we're even still in that regime, right?","speaker":"PATRICK COLLISON","timecode":{"start":619.515,"end":621.39,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"We're still making some pretty fundamental breakthroughs.","speaker":"PATRICK COLLISON","timecode":{"start":621.39,"end":624.03,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And of course, again, those, quote, \"low-hanging discoveries\" would not have been possible without a lot of this optimization and discovery in other fields.","speaker":"PATRICK COLLISON","timecode":{"start":624.03,"end":633.19,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And so I think it's probably true for a given research direction, but the relevant question for society is, is it true in aggregate.","speaker":"PATRICK COLLISON","timecode":{"start":633.2,"end":642.03,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And there, it's much less clear to me that it is.","speaker":"PATRICK COLLISON","timecode":{"start":642.03,"end":645.077,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I want to read something provocative you said in an interview with the economist Noah Smith.","speaker":"EZRA KLEIN","timecode":{"start":645.077,"end":649.41,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And you said, quote, \"Most systems get worse in at least certain ways as they scale.","speaker":"EZRA KLEIN","timecode":{"start":649.41,"end":655.9,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"The idea that science could have gotten worse in significant ways sometimes sounds strange to people.","speaker":"EZRA KLEIN","timecode":{"start":655.9,"end":660.16,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Like, we're doing so much more.","speaker":"EZRA KLEIN","timecode":{"start":660.16,"end":661.63,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"How could that be bad?","speaker":"EZRA KLEIN","timecode":{"start":661.63,"end":662.89,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But I think that misses the many examples of sensitivity of scientific processes to institutions and culture.","speaker":"EZRA KLEIN","timecode":{"start":662.89,"end":669.64,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Swiss nationals have won more than 10 times more science Nobels per capita than Italians have.","speaker":"EZRA KLEIN","timecode":{"start":669.64,"end":674.83,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"10 times.","speaker":"EZRA KLEIN","timecode":{"start":674.83,"end":676.195,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And yet, they're neighbors.","speaker":"EZRA KLEIN","timecode":{"start":676.195,"end":677.32,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And Italy certainly isn't lacking in scientific tradition --","speaker":"EZRA KLEIN","timecode":{"start":677.32,"end":680.47,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Fermi, Galileo, the oldest university in Europe, et cetera.","speaker":"EZRA KLEIN","timecode":{"start":680.47,"end":683.68,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"The 'how' of science just really matters.\"","speaker":"EZRA KLEIN","timecode":{"start":683.68,"end":687.94,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And this seems, to me, to be where your exploration really goes.","speaker":"EZRA KLEIN","timecode":{"start":687.95,"end":690.7,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So tell me what you think might have gone wrong in the \"how\" of science.","speaker":"EZRA KLEIN","timecode":{"start":690.7,"end":695.836,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So I think this point about the sensitivity of scientific outcomes to the specifics of the institutions and the cultures is very important and probably underappreciated.","speaker":"PATRICK COLLISON","timecode":{"start":695.846,"end":711.34,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"At the beginning of the 20th century, not only was the U.S. not a scientific powerhouse, but it barely had a presence in frontier research, whatsoever.","speaker":"PATRICK COLLISON","timecode":{"start":711.34,"end":725.17,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"To become a credible researcher in the U.S. in 1900, you almost certainly had to go and spend time in, most likely, Germany, and failing that, in France or England -- you know, what have you.","speaker":"PATRICK COLLISON","timecode":{"start":725.18,"end":737.38,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And by 1900, the U.S. was already a pretty prosperous place, and it had a well-educated society, as societies went.","speaker":"PATRICK COLLISON","timecode":{"start":737.38,"end":746.74,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And yet, somehow -- and it had universities, right?","speaker":"PATRICK COLLISON","timecode":{"start":746.75,"end":749.62,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I mean, Harvard was hundreds of years old by that time.","speaker":"PATRICK COLLISON","timecode":{"start":749.62,"end":752.15,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And so it checked many of the ostensible boxes, and yet, the sum total of the U.S.'","speaker":"PATRICK COLLISON","timecode":{"start":752.15,"end":758.29,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"research output as of 1900 was still de minimis.","speaker":"PATRICK COLLISON","timecode":{"start":758.29,"end":761.38,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"When James Conant, who was later president of Harvard for 20 years --","speaker":"PATRICK COLLISON","timecode":{"start":761.39,"end":766.72,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"when he went to Germany as a chemist, which was his original training, in the 1920s, he recounts how dispirited he was by what he found there and how far ahead of Harvard German research was, as of the early 20th century.","speaker":"PATRICK COLLISON","timecode":{"start":766.72,"end":785.24,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And then, for a variety of reasons, all sorts of cultural, institutional funding --","speaker":"PATRICK COLLISON","timecode":{"start":785.24,"end":792.13,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"various transformations happened.","speaker":"PATRICK COLLISON","timecode":{"start":792.13,"end":793.69,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And of course, by the latter half of the 20th century, the U.S. was the unquestioned leader at the frontier of scientific progress.","speaker":"PATRICK COLLISON","timecode":{"start":793.69,"end":801.88,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"If you look backwards, you see where that locus has been, where the most successful and fertile scientific grounds have been -- it has repeatedly moved.","speaker":"PATRICK COLLISON","timecode":{"start":801.89,"end":811.42,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"As we just said, maybe the 19th century, it was Germany.","speaker":"PATRICK COLLISON","timecode":{"start":811.42,"end":814.18,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Before that, in the 18th century, it was plausibly France.","speaker":"PATRICK COLLISON","timecode":{"start":814.19,"end":817.39,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"They had a couple of these really successful École Polytechnique and Grande École and so on.","speaker":"PATRICK COLLISON","timecode":{"start":817.39,"end":822.11,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And so as a kind of first-order empirical matter, we can just notice, huh, this really seems to matter -- and then, the example you just gave of the divergence between Switzerland and Italy.","speaker":"PATRICK COLLISON","timecode":{"start":822.11,"end":833.47,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And so then, if we kind of accept that, and we try to ask ourselves, well, specifically, what are the mechanisms?","speaker":"PATRICK COLLISON","timecode":{"start":833.48,"end":839.32,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"You know, what's actually going on?","speaker":"PATRICK COLLISON","timecode":{"start":839.32,"end":841.45,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"It's hard for me to say.","speaker":"PATRICK COLLISON","timecode":{"start":841.45,"end":843.22,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"It seems like the transmission of research culture by individual researchers matters a great deal.","speaker":"PATRICK COLLISON","timecode":{"start":843.22,"end":852.22,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And you see these kinds of pockets of the cultural transmission repeatedly crop up, where Gerty and Carl Cori -- you probably haven't heard of -- they ran a little biology lab in Missouri, and no fewer than six of their trainees, of students they trained,","speaker":"PATRICK COLLISON","timecode":{"start":852.23,"end":873.52,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"went on themselves again to win Nobel Prizes.","speaker":"PATRICK COLLISON","timecode":{"start":873.52,"end":876.31,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And if we tell ourselves a standard kind of mechanistic story as to, well, it's the funding level, it's how much are we investing in science, or it's something about whether there's an institution in the courser sense, that can possibly be amenable to it, it's very hard to explain these eddies","speaker":"PATRICK COLLISON","timecode":{"start":876.32,"end":894.43,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"where you see these pockets of excellence really produce these outsized returns.","speaker":"PATRICK COLLISON","timecode":{"start":894.43,"end":899.51,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So I think it's a complicated question.","speaker":"PATRICK COLLISON","timecode":{"start":899.51,"end":901.19,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I think all of aggregate culture, funding, institutional characteristics, and so on all contribute to it.","speaker":"PATRICK COLLISON","timecode":{"start":901.2,"end":907.13,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But if I had to isolate a single variable, it seems to me that the research culture set by specific people and the tacit knowledge transmitted through direct experience is probably the number-one thing.","speaker":"PATRICK COLLISON","timecode":{"start":907.13,"end":921.41,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"This, I think, is where I sometimes fall into my own pessimism on this.","speaker":"EZRA KLEIN","timecode":{"start":921.42,"end":925.01,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Because I want to believe, as you do, that we can double the rate of scientific advance, maybe even go further than that.","speaker":"EZRA KLEIN","timecode":{"start":925.01,"end":931.42,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But I think the prediction -- if I'm putting this on institutions, on culture, on pockets of transmission and mentorship --","speaker":"EZRA KLEIN","timecode":{"start":931.42,"end":939.72,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I think the prediction I would make is then, even if you believe, say, that America had a great 20th century, but its institutions have become sclerotic, and we've slowed down,","speaker":"EZRA KLEIN","timecode":{"start":939.72,"end":950.22,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"and everything is piled in lawsuits and review boards now, somewhere else that didn't have that, that has a different culture, that has different institutions, would be pulling way ahead.","speaker":"EZRA KLEIN","timecode":{"start":950.22,"end":960.57,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So you might think, well, China will be pulling way ahead.","speaker":"EZRA KLEIN","timecode":{"start":960.58,"end":963.02,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And you've noted this in some places.","speaker":"EZRA KLEIN","timecode":{"start":963.02,"end":965.213,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"We're getting a lot of peer-reviewed research out of China -- huge number of citations out of China.","speaker":"EZRA KLEIN","timecode":{"start":965.213,"end":969.38,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"We're not seeing them dominate the big breakthrough advances of the era.","speaker":"EZRA KLEIN","timecode":{"start":969.38,"end":974.69,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"It doesn't seem like Europe is lapping us.","speaker":"EZRA KLEIN","timecode":{"start":974.7,"end":978.03,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And so if you think this slowdown is somewhat global, then that seems to me to militate against questions of individual institutions, cultures, how different labs work, because there is so much variation that you should have some of these labs that are doing it right, some of these","speaker":"EZRA KLEIN","timecode":{"start":978.03,"end":995.21,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"places that haven't piled on a little bit too much bureaucracy.","speaker":"EZRA KLEIN","timecode":{"start":995.21,"end":999.53,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But I don't think we really see that.","speaker":"EZRA KLEIN","timecode":{"start":999.53,"end":1002.13,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"This diagnosis of these phenomena to cultural, institutional, mentorship-related, interpersonal dynamics, and your observation that it's not obviously the case, that there are other places we can pointed that are doing it so much better --","speaker":"PATRICK COLLISON","timecode":{"start":1002.14,"end":1015.78,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"for me, my takeaway is that, well, successful cultures are a pretty narrow path.","speaker":"PATRICK COLLISON","timecode":{"start":1015.78,"end":1022.14,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Homo sapiens emerged 200,000 years ago.","speaker":"PATRICK COLLISON","timecode":{"start":1022.14,"end":1025.92,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And as far as we can tell, for the first 190,000 years of our genesis, we think we were largely biologically equivalent to the people we are today.","speaker":"PATRICK COLLISON","timecode":{"start":1025.93,"end":1036.66,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But as best we can tell, there was some kind of cultural capital that those people lacked for a very extended period of time before human societies in somewhat recognizable modern form started to emerge -- agriculture, all the rest.","speaker":"PATRICK COLLISON","timecode":{"start":1036.66,"end":1050.19,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And in a similar vein, we had many billions of lives and centuries elapsed before the Industrial Revolution., and before we started to put together many of the input ingredients or enough of the input ingredients that we can get sustained improvement in standards of living","speaker":"PATRICK COLLISON","timecode":{"start":1050.2,"end":1069.76,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"and ongoing economic growth and progress.","speaker":"PATRICK COLLISON","timecode":{"start":1069.76,"end":1071.61,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And so your point about, well, as I look around, I don't see anything or anywhere that's obviously better, I agree with that.","speaker":"PATRICK COLLISON","timecode":{"start":1071.61,"end":1078.85,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But again, my takeaway is that that's what makes the question of how do we improve or how can we do somewhat better so urgent and pressing, where it's many things have to go right.","speaker":"PATRICK COLLISON","timecode":{"start":1078.86,"end":1091.53,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"It's not easy to be even as good as -- or to get to a place where things are as good as they are today.","speaker":"PATRICK COLLISON","timecode":{"start":1091.53,"end":1097.41,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"What we have is very precious.","speaker":"PATRICK COLLISON","timecode":{"start":1097.41,"end":1099.4,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I think the threads and the themes that you've been pulling on of late --","speaker":"PATRICK COLLISON","timecode":{"start":1099.4,"end":1104.28,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"all of these dynamics underscore their importance.","speaker":"PATRICK COLLISON","timecode":{"start":1104.28,"end":1107.61,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I think that's a good bridge to progress studies as an idea.","speaker":"EZRA KLEIN","timecode":{"start":1107.62,"end":1111.24,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I want to have people hold in their heads that idea that progress is very narrow, that it is a very narrow bridge that we have walked on for a very short period of time.","speaker":"EZRA KLEIN","timecode":{"start":1111.24,"end":1120.57,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But let's try to define it.","speaker":"EZRA KLEIN","timecode":{"start":1120.57,"end":1122.24,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"When you say progress here, what are you actually talking about?","speaker":"EZRA KLEIN","timecode":{"start":1122.25,"end":1126.11,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Is it just shorthand for economic growth or G.D.P.?","speaker":"EZRA KLEIN","timecode":{"start":1126.11,"end":1129.26,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"What is progress?","speaker":"EZRA KLEIN","timecode":{"start":1129.26,"end":1132.23,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Well, I don't know that I would claim to put forth some kind of definitive definition.","speaker":"PATRICK COLLISON","timecode":{"start":1132.24,"end":1139.16,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I think, to some extent, our intuitions around it are probably broadly correct.","speaker":"PATRICK COLLISON","timecode":{"start":1139.16,"end":1145.13,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And so it might not matter to define it super precisely and finely.","speaker":"PATRICK COLLISON","timecode":{"start":1145.13,"end":1149.42,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"For, me it is something along the lines of our success in realizing a liberal, pluralistic and prosperous society, and a sense among people that their offspring can and probably will do better than they themselves have, and that more broadly, the future will be better than the past,","speaker":"PATRICK COLLISON","timecode":{"start":1149.43,"end":1170.69,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"and that we're at least making incremental progress towards embodying values and morals that we collectively think we can be proud of.","speaker":"PATRICK COLLISON","timecode":{"start":1170.69,"end":1181.91,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But I don't think anything that novel in that.","speaker":"PATRICK COLLISON","timecode":{"start":1181.92,"end":1183.83,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I don't think my conception of progress would differ that materially from some kind of average aggregate over any other group of people in the country.","speaker":"PATRICK COLLISON","timecode":{"start":1183.83,"end":1193.12,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I do think there's something interesting, though, which is that if you look at eras that I think progress-studies-type people and economic-growth people and historians of economic growth study most closely, actually, some of the periods where people feel a lot of rapid progress","speaker":"EZRA KLEIN","timecode":{"start":1193.13,"end":1208.08,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"don't fit that at all.","speaker":"EZRA KLEIN","timecode":{"start":1208.08,"end":1209.71,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"You have, say, the Industrial Revolution, where life spans and lifestyle get worse for a lot of the people.","speaker":"EZRA KLEIN","timecode":{"start":1209.71,"end":1216.73,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I don't think one will look at that period as unbelievably pluralistic.","speaker":"EZRA KLEIN","timecode":{"start":1216.74,"end":1220.23,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"You have a lot of periods of war when you have very, very, very rapid technological progress, but it happens in context of much more martial societies.","speaker":"EZRA KLEIN","timecode":{"start":1220.23,"end":1229.3,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So there is an interesting tension, at least in periods -- and some of them quite long, actually --","speaker":"EZRA KLEIN","timecode":{"start":1229.3,"end":1234.15,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"where you can have fairly rapid economic progress, but it comes at a cost that I think isn't always acknowledged, but is an important thing to think about.","speaker":"EZRA KLEIN","timecode":{"start":1234.15,"end":1243.262,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Yeah.","speaker":"PATRICK COLLISON","timecode":{"start":1243.262,"end":1244.22,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So I don't think you could point to some of these periods in the past and say that they definitively embody to the extent that we would fully aspire to some of these broader traits and characteristics.","speaker":"PATRICK COLLISON","timecode":{"start":1244.22,"end":1256.97,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But I think the question is more, what are they doing as -- you have to judge it relative to the baseline that preceded them.","speaker":"PATRICK COLLISON","timecode":{"start":1256.97,"end":1263.73,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I don't know that the 18th century in the U.K. is some ideal as a society.","speaker":"PATRICK COLLISON","timecode":{"start":1263.74,"end":1270.02,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But if you compare it to the 16th century in the U.K., the ideals and ideas of natural rights and religious tolerance and so on -- they were somewhat better embodied by the 18th century than they had just a couple of centuries previously.","speaker":"PATRICK COLLISON","timecode":{"start":1270.02,"end":1284.18,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And similarly, in the U.S., say, during either war or the '30s or whatever, again, it's not like that was any kind of perfect society, but assessed relative to the society of 1830, I think it compares relatively favorably.","speaker":"PATRICK COLLISON","timecode":{"start":1284.19,"end":1297.77,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I think it's not a coincidence that Adam Smith --","speaker":"PATRICK COLLISON","timecode":{"start":1297.77,"end":1302.09,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"his first book, of course, was on ethics and morals and trying to instill better general ideals and behaviors across a society.","speaker":"PATRICK COLLISON","timecode":{"start":1302.09,"end":1310.19,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And maybe after that, he then argued for and laid many of the foundations of what we would recognize as modern economics.","speaker":"PATRICK COLLISON","timecode":{"start":1310.2,"end":1317.21,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So I don't think it's perfect.","speaker":"PATRICK COLLISON","timecode":{"start":1317.21,"end":1318.72,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But on average, I think the correlation is positive.","speaker":"PATRICK COLLISON","timecode":{"start":1318.72,"end":1321.41,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So let's talk about the Industrial Revolution for a little bit here.","speaker":"EZRA KLEIN","timecode":{"start":1321.42,"end":1324.98,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I think a lot of people locate a takeoff in human living standards -- it continues to this day -- there.","speaker":"EZRA KLEIN","timecode":{"start":1324.98,"end":1332.8,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And it's strange in a way, right?","speaker":"EZRA KLEIN","timecode":{"start":1332.8,"end":1334.72,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"\"There\" is a very geographically contiguous spot.","speaker":"EZRA KLEIN","timecode":{"start":1334.72,"end":1337.42,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"It's the U.K. --","speaker":"EZRA KLEIN","timecode":{"start":1337.42,"end":1338.83,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"England, actually, I should say, at that point.","speaker":"EZRA KLEIN","timecode":{"start":1338.83,"end":1341.26,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And there is a moment in time that probably could have come at another moment in time, depending on how human history plays out in the counterfactual.","speaker":"EZRA KLEIN","timecode":{"start":1341.27,"end":1350.4,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I know that you have an interest in the theories of why then, why there.","speaker":"EZRA KLEIN","timecode":{"start":1350.4,"end":1355.1,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"How do you work your way through them?","speaker":"EZRA KLEIN","timecode":{"start":1355.1,"end":1356.9,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"What do you think is persuasive for why then, why there?","speaker":"EZRA KLEIN","timecode":{"start":1356.9,"end":1359.707,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Well, you know, again, I caveat.","speaker":"PATRICK COLLISON","timecode":{"start":1359.707,"end":1361.79,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"With all of these topics we're discussing through this podcast, maybe the first-order banner for all of them should be, I don't know, these are my best guesses, and I think it's important that all of us were pretty humble in the claims and the assertions and the beliefs that we hold.","speaker":"PATRICK COLLISON","timecode":{"start":1361.79,"end":1376.1,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Recently, I've been reading a bunch of Irish and Scottish writers around then.","speaker":"PATRICK COLLISON","timecode":{"start":1376.11,"end":1383.3,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"It's very interesting, because for both the Irish and the Scots, there was a sort of a pressing and kind of obvious question where England was much more prosperous than they were or we were.","speaker":"PATRICK COLLISON","timecode":{"start":1383.3,"end":1398.24,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And there's no super obvious explanation for that.","speaker":"PATRICK COLLISON","timecode":{"start":1398.24,"end":1400.62,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"There wasn't an obvious climatic or natural resource endowment that England benefited from that was lacking in Ireland or Scotland.","speaker":"PATRICK COLLISON","timecode":{"start":1400.62,"end":1407.9,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"It wasn't like England was actually a vastly larger polity.","speaker":"PATRICK COLLISON","timecode":{"start":1407.91,"end":1410.84,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"The orders of magnitude were comparable.","speaker":"PATRICK COLLISON","timecode":{"start":1410.84,"end":1412.64,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And Bishop Berkeley wrote this book, \"The Querist.\"","speaker":"PATRICK COLLISON","timecode":{"start":1412.64,"end":1417.65,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"He was asking these questions directly, just like, what's going on?","speaker":"PATRICK COLLISON","timecode":{"start":1417.65,"end":1420.68,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"What's wrong with Ireland?","speaker":"PATRICK COLLISON","timecode":{"start":1420.68,"end":1421.82,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"You know, why can't we do this?","speaker":"PATRICK COLLISON","timecode":{"start":1421.82,"end":1423.2,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And then, you have the Act of Union in 1707, uniting Scotland and England -- and sort of similarly, of all these Scottish thinkers being like, all right, we're now literally the same country.","speaker":"PATRICK COLLISON","timecode":{"start":1423.21,"end":1432.08,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Why are we so much more impoverished?","speaker":"PATRICK COLLISON","timecode":{"start":1432.08,"end":1434.42,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And then, if you shift to England, there's Joel Mokyr and -- you've read his work -- and more recently, people like Anton Howes.","speaker":"PATRICK COLLISON","timecode":{"start":1434.42,"end":1440.48,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And in a similar vein, they go back to --","speaker":"PATRICK COLLISON","timecode":{"start":1440.49,"end":1444.35,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I mean, the word, improvement, came from Francis Bacon, or it was kind of popularized as a concept by Francis Bacon.","speaker":"PATRICK COLLISON","timecode":{"start":1444.35,"end":1451.692,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But that's noteworthy, right?","speaker":"PATRICK COLLISON","timecode":{"start":1451.692,"end":1452.9,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Like, that was not a pervasive broad concept in the 15th century.","speaker":"PATRICK COLLISON","timecode":{"start":1452.9,"end":1457.36,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I mean, literally, the word, improvement, in this broader societal context, came from word, \"translated,\" at the beginning of the 17th century.","speaker":"PATRICK COLLISON","timecode":{"start":1457.37,"end":1464.33,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And the ultimate conclusion that these historians and scholars and analysts of the Industrial Revolution come to -- and I think it's a correct one -- is somehow, whether it's through Bacon or Newton or various of the tinkerers who produced some of the earliest technological breakthroughs,","speaker":"PATRICK COLLISON","timecode":{"start":1464.33,"end":1485.12,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"that somehow, this improving mind-set became pervasive.","speaker":"PATRICK COLLISON","timecode":{"start":1485.12,"end":1489.68,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"You had societies explicitly --","speaker":"PATRICK COLLISON","timecode":{"start":1489.69,"end":1492.26,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"like the Hartlib Circle or the Lunar Society, or the Select Society, and the club, and so on -- all these societies explicitly devoted to figuring out ways to advance the state of affairs that prevailed.","speaker":"PATRICK COLLISON","timecode":{"start":1492.26,"end":1506.36,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And these societies were comprised of many of the leading people and thinkers and so on of the day.","speaker":"PATRICK COLLISON","timecode":{"start":1506.36,"end":1511.98,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And it seems maybe a bit satisfyingly squishy to attribute it to something so hard to pin down.","speaker":"PATRICK COLLISON","timecode":{"start":1511.99,"end":1520.22,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But as you run through all the possible other explanations, it's differences in IP law.","speaker":"PATRICK COLLISON","timecode":{"start":1520.22,"end":1525.59,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"It's difference in the Malthusian conditions.","speaker":"PATRICK COLLISON","timecode":{"start":1525.59,"end":1528.29,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"It's difference in the prevalence of coal, you know, et cetera, et cetera.","speaker":"PATRICK COLLISON","timecode":{"start":1528.29,"end":1532.61,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Through various cross-sectional analyses, you can exclude most of these in looking at all of Ireland, Scotland, and England.","speaker":"PATRICK COLLISON","timecode":{"start":1532.61,"end":1540.95,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"It really does seem to me that differences in the mind-set and in the culture are where you have to net out.","speaker":"PATRICK COLLISON","timecode":{"start":1540.96,"end":1547.58,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And that's not to say maybe that it's fully sufficient.","speaker":"PATRICK COLLISON","timecode":{"start":1547.58,"end":1550.91,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"There might be other preconditions that are important.","speaker":"PATRICK COLLISON","timecode":{"start":1550.91,"end":1553.86,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And then, maybe as a last thing to say, it is striking to me that many of these kind of original 18th-century economic writers and thinkers -- and again, the kind of people we look to as the founders of much of the discipline -- that they themselves were kind of centrally preoccupied with this.","speaker":"PATRICK COLLISON","timecode":{"start":1553.86,"end":1572.99,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And yeah, they were in favor of free trade and specialization and human labor and lots of these concepts that we're now very familiar with, but they really thought that general mind-set played a big role, too.","speaker":"PATRICK COLLISON","timecode":{"start":1573,"end":1585.78,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So let's talk about Joel Mokyr ideas for a minute.","speaker":"EZRA KLEIN","timecode":{"start":1585.79,"end":1588.46,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So Mokyr is an economic historian.","speaker":"EZRA KLEIN","timecode":{"start":1588.46,"end":1591.12,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"People should read his book, \"The Culture of Growth,\" which is really fascinating.","speaker":"EZRA KLEIN","timecode":{"start":1591.12,"end":1594.83,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"He argues, as you're saying, that in this period, this mind-set that we can increase the store of usable knowledge, and then use it to alter nature, to better the human condition, takes hold.","speaker":"EZRA KLEIN","timecode":{"start":1594.83,"end":1607.19,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"That's a new mind-set.","speaker":"EZRA KLEIN","timecode":{"start":1607.2,"end":1608.28,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"It's different than religious ideas of the past.","speaker":"EZRA KLEIN","timecode":{"start":1608.28,"end":1610.66,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"It's different than cultural ideas of the present.","speaker":"EZRA KLEIN","timecode":{"start":1610.66,"end":1613.17,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And that, plus a bunch of other things, particularly the republic of letters, the way people are writing letters back and forth, kind of combine into a culture that is able to grow.","speaker":"EZRA KLEIN","timecode":{"start":1613.17,"end":1622.3,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But one of the things that I really take from his work, that sits in my head, is he believes it's all very contingent.","speaker":"EZRA KLEIN","timecode":{"start":1622.31,"end":1629.37,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"He really believes it might have not happened.","speaker":"EZRA KLEIN","timecode":{"start":1629.37,"end":1632.78,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But the other is that I think it opens up this question that as a tech person, I'm curious to hear your thoughts on, which is, he really believes --","speaker":"EZRA KLEIN","timecode":{"start":1632.78,"end":1642.1,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Mokyr really believes -- that there is a communications infrastructure that arises at that time, that has a kind of culture of generosity and argument and honesty in it, and is built on writing letters slowly to one another, and then copying those letters over to other people.","speaker":"EZRA KLEIN","timecode":{"start":1642.1,"end":1657.04,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And that culture is really good for intellectual advancement.","speaker":"EZRA KLEIN","timecode":{"start":1657.05,"end":1660.86,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I think one of the promises of the internet and the age we live in is, it's all faster.","speaker":"EZRA KLEIN","timecode":{"start":1660.86,"end":1664.6,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"We can write to people immediately.","speaker":"EZRA KLEIN","timecode":{"start":1664.6,"end":1666.94,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Things we write can go viral and be seen by 5 million people all of a sudden.","speaker":"EZRA KLEIN","timecode":{"start":1666.94,"end":1670.9,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And that was going to speed up economic growth really, really rapidly.","speaker":"EZRA KLEIN","timecode":{"start":1670.91,"end":1674.11,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I would say, you don't see that.","speaker":"EZRA KLEIN","timecode":{"start":1674.11,"end":1676.94,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So I'm curious how you think about communication cultures here and what you think for all the advantages of ours we might not have.","speaker":"EZRA KLEIN","timecode":{"start":1676.94,"end":1685.87,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I mean, I think it's hard to say in aggregate.","speaker":"PATRICK COLLISON","timecode":{"start":1685.88,"end":1691.33,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I feel it's pretty likely that the effects are very heterogeneous across different populations.","speaker":"PATRICK COLLISON","timecode":{"start":1691.33,"end":1699.61,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And you've made the case that you think Twitter is bad for journalism and for journalists.","speaker":"PATRICK COLLISON","timecode":{"start":1699.61,"end":1706.57,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I guess you live this yourself with your now mostly inactive Twitter account, I guess, apart from announcements.","speaker":"PATRICK COLLISON","timecode":{"start":1706.58,"end":1712.97,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I think in the case of the internet, that it's almost certainly a tremendously large gain that billions of people now have access to educational materials.","speaker":"PATRICK COLLISON","timecode":{"start":1712.97,"end":1726.13,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And some of the otherwise hard-to-communicate tacit knowledge -- that things like YouTube videos now made legible and available.","speaker":"PATRICK COLLISON","timecode":{"start":1726.13,"end":1735.65,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I think it's true that there are various gravity equations that we see across different disciplines.","speaker":"PATRICK COLLISON","timecode":{"start":1735.66,"end":1743.35,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I mean, in economies themselves, in trade, where you rapidly decline in propensities to trade as countries get further from each other -- but you have versions of this in academic disciplines as well, where geographic distance correlates inversely with likelihood of the exchange of ideas and so on.","speaker":"PATRICK COLLISON","timecode":{"start":1743.35,"end":1757.61,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I think it's clearly the case that the sort of reaction surface area has increased substantially by the internet there and represents a kind of efficiency gain for people looking to exchange in ideas.","speaker":"PATRICK COLLISON","timecode":{"start":1757.62,"end":1771.88,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Many of the companies that Stripe works with are remote companies, and they might employ people across myriad countries, and that's a kind of communication and efficiency gain that would certainly not otherwise be achievable.","speaker":"PATRICK COLLISON","timecode":{"start":1771.88,"end":1785.08,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I think it's worth recognizing that the aggregate amount of G.D.P. that we are creating or gaining every year is so much larger now than --","speaker":"PATRICK COLLISON","timecode":{"start":1785.09,"end":1795.91,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I mean, the percentage might be the same.","speaker":"PATRICK COLLISON","timecode":{"start":1795.91,"end":1797.69,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But the total amount of stuff happening, or the increasing amount of stuff happening, is so much larger now than it was 100 or 200 or 300 years ago.","speaker":"PATRICK COLLISON","timecode":{"start":1797.69,"end":1806.45,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And so for all of those reasons, I think we should give superior communication technologies and faster communication technologies a significant amount of credit, even though the ways in which those are manifests might be hard to measure and somewhat prosaic.","speaker":"PATRICK COLLISON","timecode":{"start":1806.46,"end":1821.32,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Take my mom, for example.","speaker":"PATRICK COLLISON","timecode":{"start":1821.33,"end":1823.15,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"My mom works with a hospital in Minnesota.","speaker":"PATRICK COLLISON","timecode":{"start":1823.15,"end":1827.2,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Our youngest brother has a physical disability.","speaker":"PATRICK COLLISON","timecode":{"start":1827.2,"end":1829.52,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And in the course of that, she trained herself in treatment for cerebral palsy, this condition, and she wrote a book about it, and she did a master's in this.","speaker":"PATRICK COLLISON","timecode":{"start":1829.52,"end":1837.91,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And now, she's trying to improve treatment for this condition throughout Ireland, in the U.S. and other countries as well.","speaker":"PATRICK COLLISON","timecode":{"start":1837.91,"end":1844.78,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"She's a retired Irish mother who spends some of her year living in the U.S. near her sons, spends the rest of her year living in Ireland, working at a hospital in Minnesota, who just got a proposal to have her book translated into German a couple of days ago.","speaker":"PATRICK COLLISON","timecode":{"start":1844.79,"end":1863.08,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And that's a relatively prosaic story, but literally, millions of these stories exist in kind of aggregate form around the world.","speaker":"PATRICK COLLISON","timecode":{"start":1863.08,"end":1869.98,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"To circle back to the initial thrust of your question, though, I think it's at least possible that the internet is bad for civic discourse.","speaker":"PATRICK COLLISON","timecode":{"start":1869.99,"end":1877.51,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I'm not saying it is, but it's certainly in the realm of plausibility -- and that perhaps both things are true, where there's some kind of iceberg where there are these enormous welfare gains that are not that legible, not that visible, lie beneath the surface,","speaker":"PATRICK COLLISON","timecode":{"start":1877.51,"end":1891.61,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"and then certain of the most visible manifestations, like what we see on cable news or what we see written in the papers --","speaker":"PATRICK COLLISON","timecode":{"start":1891.61,"end":1899.14,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"perhaps that is worse, and perhaps, slightly more structural judiciousness would be desirable there.","speaker":"PATRICK COLLISON","timecode":{"start":1899.14,"end":1907.243,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I want to try to flip that and suggest that --","speaker":"EZRA KLEIN","timecode":{"start":1907.243,"end":1909.66,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"because I'm going to push some counter ideas on why we maybe don't see as much progress as we wish we did.","speaker":"EZRA KLEIN","timecode":{"start":1909.66,"end":1915.96,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But one is that I think possibly, very large welfare losses lie beneath the surface.","speaker":"EZRA KLEIN","timecode":{"start":1915.96,"end":1921.03,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And beneath the surface of stories like the one you just told about your mother, I think we all have stories of ways or people for whom the internet has unlocked a possibility.","speaker":"EZRA KLEIN","timecode":{"start":1921.03,"end":1930.78,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I mean, my whole career is built on the internet.","speaker":"EZRA KLEIN","timecode":{"start":1930.79,"end":1933.002,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I was an early blogger.","speaker":"EZRA KLEIN","timecode":{"start":1933.002,"end":1933.96,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I got rejected from my student newspaper.","speaker":"EZRA KLEIN","timecode":{"start":1933.96,"end":1936.6,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And if there was no blogging, like, god knows what would have happened to me.","speaker":"EZRA KLEIN","timecode":{"start":1936.6,"end":1940.11,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"[LAUGHS] I mean, nothing too terrible, probably, but I wouldn't have the career I have today.","speaker":"EZRA KLEIN","timecode":{"start":1940.11,"end":1945.15,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And at the same time, I think that the group of people who, by luck or by temperament, proved very, very good at using the internet, to some degree, distracts from the many, many, many people for whom the internet is fundamentally a distraction machine,","speaker":"EZRA KLEIN","timecode":{"start":1945.16,"end":1960.63,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"or for whom the internet is creating, because of what we built on it.","speaker":"EZRA KLEIN","timecode":{"start":1960.63,"end":1966.62,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"You know, shorter attention spans -- how many people would have had an idea, sitting in a room by themselves, or taking a walk, that they never have now, because they never have to have a moment where they're thinking alone?","speaker":"EZRA KLEIN","timecode":{"start":1966.62,"end":1977.43,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And so one thing that I think we're all loathe to do is we'll talk a lot about how it's weird that we have so much more knowledge, but productivity isn't increasing faster.","speaker":"EZRA KLEIN","timecode":{"start":1977.44,"end":1988.44,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"It's weird that we have so much more rapid communication between researchers, but science isn't advancing faster.","speaker":"EZRA KLEIN","timecode":{"start":1988.44,"end":1994.53,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And then, the idea that maybe there are things happening to us that makes us less able to use that increasing stock of knowledge well, or makes us less able to collaborate in a useful way, I think, gets dismissed rather quickly.","speaker":"EZRA KLEIN","timecode":{"start":1994.53,"end":2010.66,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But I don't think it's totally implausible.","speaker":"EZRA KLEIN","timecode":{"start":2010.67,"end":2012.525,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Now, I don't want to say, like, the greatest technology we ever had was letter-writing.","speaker":"EZRA KLEIN","timecode":{"start":2012.525,"end":2016.15,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Obviously, the greatest technology we ever had was blogging in the early aughts when I became a blogger.","speaker":"EZRA KLEIN","timecode":{"start":2016.15,"end":2020.483,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And whatever happened in your 20s is, like, as good as it was ever going to get.","speaker":"EZRA KLEIN","timecode":{"start":2020.483,"end":2024.53,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But I do wonder about these questions.","speaker":"EZRA KLEIN","timecode":{"start":2024.54,"end":2026.3,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I think something Mokyr is right to put a lot of attention on is communicative cultures.","speaker":"EZRA KLEIN","timecode":{"start":2026.3,"end":2031.66,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Communication is how we collaborate.","speaker":"EZRA KLEIN","timecode":{"start":2031.66,"end":2033.97,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And if communication is in any way getting worse, it's going to have pretty big macro effects.","speaker":"EZRA KLEIN","timecode":{"start":2033.97,"end":2038.12,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"The other thing is if you believe these cultures matter, weirdly, as big as we're getting, the internet allows a certain disciplines culture to stretch boundaries and borders in time in a way that it would have been harder.","speaker":"EZRA KLEIN","timecode":{"start":2038.13,"end":2049.03,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I suspect that labs were more different 50 years ago than they are today.","speaker":"EZRA KLEIN","timecode":{"start":2049.03,"end":2053.389,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"The countries and the disciplines of researchers and the cultures of researchers in countries or cities are more different from each other 50 years ago than today, which is great if we have the best of all cultures today,","speaker":"EZRA KLEIN","timecode":{"start":2053.399,"end":2066.01,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"but it's not that great if you actually think variation is really important.","speaker":"EZRA KLEIN","timecode":{"start":2066.01,"end":2069.636,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Let's wrap up there.","speaker":"PATRICK COLLISON","timecode":{"start":2069.636,"end":2071.219,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So first, I agree, as a basic matter, that there are welfare losses occurring across society that we should be worried about, and probably everybody listening to this is familiar with the Stephen Pinker case for optimism, and rather than focusing in the headlines,","speaker":"PATRICK COLLISON","timecode":{"start":2071.219,"end":2089.67,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"you zoom out, look at these long-term time series.","speaker":"PATRICK COLLISON","timecode":{"start":2089.67,"end":2091.989,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And once one does that, things seem a lot more encouraging, whether you look at it by income or life expectancy or infant mortality or choose your metric.","speaker":"PATRICK COLLISON","timecode":{"start":2091.989,"end":2099.63,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Something that's been striking to me of late is if you change the x-axis on those time series, and look at many of those phenomena and trends over a much shorter window, the valence changes substantially, and life expectancy in the U.S. is now, in fact, declining.","speaker":"PATRICK COLLISON","timecode":{"start":2099.64,"end":2115.89,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"According to C.D.C. data, 54 percent of teenage girls now report persistent feelings of sadness and hopelessness.","speaker":"PATRICK COLLISON","timecode":{"start":2115.89,"end":2124.62,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And you could say, well, teenagers were never stereotyped as the most cheerful lot, but we do have some degree of longitudinal data here, and that number is up from being in the 20s as recently as 2009.","speaker":"PATRICK COLLISON","timecode":{"start":2124.62,"end":2138.78,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"1\u002F2 the population now is either prediabetic or diabetic -- again, according to the C.D.C. Basically, point is, when we look at more recent windows, I think there are plenty of aggregate, emergent, complicated outcomes and phenomena that should give us concern.","speaker":"PATRICK COLLISON","timecode":{"start":2138.79,"end":2158.7,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"On the degree to which we should attribute the diagnosis to the internet or to our kind of communication media more broadly, it's less clear to me in that --","speaker":"PATRICK COLLISON","timecode":{"start":2158.7,"end":2170.52,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"not saying it's not true, but presumably, the life expectancy one is not -- or at least if it is, the mechanism has to be very complicated.","speaker":"PATRICK COLLISON","timecode":{"start":2170.52,"end":2178.2,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"There are a bunch of other health-related ones.","speaker":"PATRICK COLLISON","timecode":{"start":2178.21,"end":2181.24,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So take, for example, say, the incidence of diabetes or pre-diabetes.","speaker":"PATRICK COLLISON","timecode":{"start":2181.24,"end":2186.228,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And you could say, OK, fine, all those things might be true, but they're totally different.","speaker":"PATRICK COLLISON","timecode":{"start":2186.228,"end":2190.02,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I guess the question I wonder about is, well, we know that lots of basic biological outcomes are correlated with mental states and so on.","speaker":"PATRICK COLLISON","timecode":{"start":2190.02,"end":2198.79,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And so to what degree is there some more nuanced and complicated relationship there?","speaker":"PATRICK COLLISON","timecode":{"start":2198.8,"end":2203.67,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But I think it's a fair question, and I wonder a lot about it myself.","speaker":"PATRICK COLLISON","timecode":{"start":2203.67,"end":2206.715,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Let me ask you about how you think, over the long period here, about the relationship between technology and equity or egalitarianism.","speaker":"EZRA KLEIN","timecode":{"start":2237.73,"end":2245.358,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And something specific is in my mind.","speaker":"EZRA KLEIN","timecode":{"start":2245.358,"end":2246.9,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I flicked earlier at the way the Industrial Revolution, for an extended period of time, seems to have reduced a lot of people's living standards.","speaker":"EZRA KLEIN","timecode":{"start":2246.9,"end":2254.04,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And it wasn't till later you had changes in redistribution in labor unions and labor protections that the amount of material prosperity that was generating created more broad-based prosperity, particularly at a very high level.","speaker":"EZRA KLEIN","timecode":{"start":2254.04,"end":2269.092,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I don't know that you can sustain that kind of thing today.","speaker":"EZRA KLEIN","timecode":{"start":2269.092,"end":2271.55,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"We have much more a small-d democratic culture.","speaker":"EZRA KLEIN","timecode":{"start":2271.55,"end":2273.44,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"If things aren't working for people, it's much easier for them to organize and be heard.","speaker":"EZRA KLEIN","timecode":{"start":2273.44,"end":2277.16,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I think there's a much more direct and complicated relationship now between whether or not people feel benefited by technology, and whether or not they are going to accept the conditions and the risks of rapid technological advance.","speaker":"EZRA KLEIN","timecode":{"start":2277.17,"end":2288.89,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But I'm curious, from your vantage point, how you see that both kind of historically and currently.","speaker":"EZRA KLEIN","timecode":{"start":2288.89,"end":2293.61,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I agree with that.","speaker":"PATRICK COLLISON","timecode":{"start":2293.61,"end":2295.11,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I worry a lot about the basic stability of a society that does not successfully generate and make sufficiently broadly accessible the benefits of economic growth.","speaker":"PATRICK COLLISON","timecode":{"start":2295.11,"end":2309.32,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"The world simply has too little prosperity.","speaker":"PATRICK COLLISON","timecode":{"start":2309.32,"end":2312.95,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And if it is not the case that people in the U.S. or people in any country --","speaker":"PATRICK COLLISON","timecode":{"start":2312.95,"end":2321.08,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"if they either feel like things aren't progressing, or if they feel like maybe somewhere distant from them, things are progressing but they personally will never be able to benefit from it, I think we put ourselves in a very dangerous and likely unstable equilibrium.","speaker":"PATRICK COLLISON","timecode":{"start":2321.08,"end":2338.28,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And if you go back to --","speaker":"PATRICK COLLISON","timecode":{"start":2338.29,"end":2342.2,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"well, you don't have to go back very far in history to see, obviously, plenty of instances where this kind of instability brought the whole house of cards down.","speaker":"PATRICK COLLISON","timecode":{"start":2342.2,"end":2350.66,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And so as a consequence of that, I worry a lot about, how do we simply make sure that -- or one of the small things we each individually can do to try to make sure that society is generating enough economic gain and enough broadly experienced welfare gain that the whole compact can be maintained?","speaker":"PATRICK COLLISON","timecode":{"start":2350.66,"end":2370.43,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And again, I don't think there's a ready neat kind of singular answer to that.","speaker":"PATRICK COLLISON","timecode":{"start":2370.44,"end":2374.21,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Maybe Stripe as part of our small little contribution in one little fissure.","speaker":"PATRICK COLLISON","timecode":{"start":2374.21,"end":2379.8,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But I think the central question you're getting at is super important.","speaker":"PATRICK COLLISON","timecode":{"start":2379.8,"end":2384.03,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And one of the questions I wonder about there -- we've talked about the way progress has been very geographically lumpy, let's call it, right?","speaker":"EZRA KLEIN","timecode":{"start":2384.04,"end":2391.82,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"There's a lot that happens in very small places, and it ends up affecting the whole world.","speaker":"EZRA KLEIN","timecode":{"start":2391.82,"end":2396.59,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Obviously, then, the gains of progress sometimes have that quality, too.","speaker":"EZRA KLEIN","timecode":{"start":2396.59,"end":2400.97,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I do think of one of the politically destabilizing effects of the past, let's call it, 30 or 40 years of digital progress, is being the concentrations of wealth.","speaker":"EZRA KLEIN","timecode":{"start":2400.98,"end":2411.56,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"We just used to have a lot more spread.","speaker":"EZRA KLEIN","timecode":{"start":2411.56,"end":2414.32,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Even putting the questions of rising inequality aside, just where rich people were was different.","speaker":"EZRA KLEIN","timecode":{"start":2414.32,"end":2419.16,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And so where they were giving a lot of money to the local hospital was more spread out, say, across the country or in other countries across the land.","speaker":"EZRA KLEIN","timecode":{"start":2419.17,"end":2428.09,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But here, even as the internet is supposed to democratize distance, and in many ways, has --","speaker":"EZRA KLEIN","timecode":{"start":2428.09,"end":2432.89,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I mean, telework is not a fake phenomenon.","speaker":"EZRA KLEIN","timecode":{"start":2432.89,"end":2435.77,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"It has really concentrated the wealth of that to, literally, where we're sitting, but to New York.","speaker":"EZRA KLEIN","timecode":{"start":2435.77,"end":2442.58,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"There's a lot of money now in Austin.","speaker":"EZRA KLEIN","timecode":{"start":2442.58,"end":2444.5,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And then, on top of that, you often have barriers of entry, in terms of how many homes can be bought.","speaker":"EZRA KLEIN","timecode":{"start":2444.51,"end":2448.82,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So it's not even like people can move to the place where all the economic opportunity is happening.","speaker":"EZRA KLEIN","timecode":{"start":2448.82,"end":2453.36,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I do think that creates some of the skepticism you see of technology.","speaker":"EZRA KLEIN","timecode":{"start":2453.36,"end":2458.37,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I don't think a lot of people's --","speaker":"EZRA KLEIN","timecode":{"start":2458.38,"end":2460.25,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I think people are really excited about a lot of the goods they've gotten from it.","speaker":"EZRA KLEIN","timecode":{"start":2460.25,"end":2464.85,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But in this kind of macro political sense, as you're saying, in a period of a lot of change, a lot of folks with real backing in the data don't feel life has gotten better at the macro level.","speaker":"EZRA KLEIN","timecode":{"start":2464.85,"end":2475.94,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Life expectancy, happiness, political stability --","speaker":"EZRA KLEIN","timecode":{"start":2475.95,"end":2479.185,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"it's not like you can look around and say, well, I got this computer in my pocket, and everything else is going great, too.","speaker":"EZRA KLEIN","timecode":{"start":2479.185,"end":2484.31,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"It's like, I got this computer in my pocket, and what it keeps telling me is that everything is going to hell.","speaker":"EZRA KLEIN","timecode":{"start":2484.31,"end":2489.993,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Now, maybe it's telling me that a little bit too much, but there is validity to the narrative.","speaker":"EZRA KLEIN","timecode":{"start":2489.993,"end":2493.91,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Yeah.","speaker":"PATRICK COLLISON","timecode":{"start":2493.982,"end":2494.94,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So again, vehement in agreement on the sort of central importance of making sure that improvements in the standard of living are actually broadly realized across the society.","speaker":"PATRICK COLLISON","timecode":{"start":2494.94,"end":2505.68,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"That, too, I think, could serve as a manifesto for some of these Progress Studies ideas.","speaker":"PATRICK COLLISON","timecode":{"start":2505.68,"end":2509.82,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"On the internet in particular, or on technology and the technology sector and so forth, I think it's complicated and difficult to try to sort of fully collapse or linearize it or something, where on the one hand, you have some of these concentration dynamics you identify.","speaker":"PATRICK COLLISON","timecode":{"start":2509.83,"end":2524.52,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"At the same time, of course, it is also a tremendous and incredible dispersal agent in making some of those possibilities and opportunities be more broadly available.","speaker":"PATRICK COLLISON","timecode":{"start":2524.52,"end":2534.75,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I think it's dangerous to take an excessively U.S.-centric perspective here.","speaker":"PATRICK COLLISON","timecode":{"start":2534.76,"end":2538.8,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"If you interact with or look at survey data, or otherwise try to assess what's the sentiment of people in Poland, what's the sentiment of people in India, or what's the sentiment of people in Indonesia, they view the internet extremely positively.","speaker":"PATRICK COLLISON","timecode":{"start":2538.8,"end":2551.73,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I think correctly so, where their opportunities for advancement would be substantially curtailed in the absence of much of what the internet makes possible.","speaker":"PATRICK COLLISON","timecode":{"start":2551.73,"end":2559.68,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I think in places like the U.S., or actually, even at home in Ireland, some of this story is complicated by lots of other things, but including -- and I think, substantially -- dynamics around housing policy, where there's an extensive literature showing that, for example,","speaker":"PATRICK COLLISON","timecode":{"start":2559.69,"end":2573.58,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"a very substantial moderating effect on the increase in wealth inequality that would otherwise have happened, or income inequality, was geographic reallocation and people responding rationally to, OK, things in New York are going great, or things in California are going great.","speaker":"PATRICK COLLISON","timecode":{"start":2573.58,"end":2592.08,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And if you look at the rate of increase of the Californian population, say, through the 1960s, that was a tremendously potent mechanism for us redistributing some of the economic gains that were being realized at the time.","speaker":"PATRICK COLLISON","timecode":{"start":2592.09,"end":2604.53,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And of course, now, we have this crazy position, where California is losing population at the same time where the market caps of these companies and the profits of these companies are increasing very rapidly.","speaker":"PATRICK COLLISON","timecode":{"start":2604.53,"end":2614.89,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But as one assesses that dynamic and tries to ask the question of, well, why aren't these gains being better or more broadly distributed, it's certainly not clear to me that the answer even lies in the realm of technology qua technology.","speaker":"PATRICK COLLISON","timecode":{"start":2614.9,"end":2627.58,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I think it's certainly more broadly, again, some of these considerations like geographic allocation.","speaker":"PATRICK COLLISON","timecode":{"start":2627.58,"end":2636.287,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Let me ask one more question on the geographic dimension, and then I'll move on to it.","speaker":"EZRA KLEIN","timecode":{"start":2636.287,"end":2640.37,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And it's on my mind, in part because when I try to think about progress, when I try to think about what inventions and innovations are coming really quickly, I actually see a bunch here.","speaker":"EZRA KLEIN","timecode":{"start":2640.37,"end":2649.52,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I'll use A.I. as an example.","speaker":"EZRA KLEIN","timecode":{"start":2649.52,"end":2651.14,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I've met people who are trying to automate a bunch of legal contracts.","speaker":"EZRA KLEIN","timecode":{"start":2651.15,"end":2654.23,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"It makes a ton of sense.","speaker":"EZRA KLEIN","timecode":{"start":2654.23,"end":2656.12,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"People pay a lot all over the country -- to some degree, all over the world --","speaker":"EZRA KLEIN","timecode":{"start":2656.12,"end":2660.08,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"to get fairly basic legal contracts drawn up -- wills and real estate documents and merger agreements and all kinds of -- from the small to the large.","speaker":"EZRA KLEIN","timecode":{"start":2660.08,"end":2669.96,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"If you imagine that getting really effectively automated, though --","speaker":"EZRA KLEIN","timecode":{"start":2669.97,"end":2673.8,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"you think about Saint Louis, Missouri, where some of the people who are important pillars of the community work in law firms there, and what they do is contracts.","speaker":"EZRA KLEIN","timecode":{"start":2673.81,"end":2683.38,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"They do estate planning and all the things that people have to do in contracts.","speaker":"EZRA KLEIN","timecode":{"start":2683.38,"end":2687.37,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And if it actually does get concentrated to really, really great contracting firms in the Bay Area or in New York, on the one hand, the democratizing potential will really be realized.","speaker":"EZRA KLEIN","timecode":{"start":2687.37,"end":2697.56,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Those contracts will get cheaper.","speaker":"EZRA KLEIN","timecode":{"start":2697.56,"end":2699.67,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"There's also a theory in crypto of smart contracts.","speaker":"EZRA KLEIN","timecode":{"start":2699.68,"end":2702.57,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And on the other hand, you really will have a lot of that -- the gains of that, economically, going to smaller areas and aggregated across a bunch of different domains.","speaker":"EZRA KLEIN","timecode":{"start":2702.57,"end":2714.25,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So graphic design, in all kinds of areas of the country -- midlevel graphic designers get paid to make logos for local businesses.","speaker":"EZRA KLEIN","timecode":{"start":2714.25,"end":2722.52,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"It's pretty clear they're going to be able to do that really, really easily on things like DALL-E pretty fast.","speaker":"EZRA KLEIN","timecode":{"start":2722.53,"end":2728.49,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So you can imagine a lot of that area getting wiped out.","speaker":"EZRA KLEIN","timecode":{"start":2728.49,"end":2731.023,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And you kind of run through a couple of these.","speaker":"EZRA KLEIN","timecode":{"start":2731.023,"end":2732.94,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And before you get to really unbelievable and sci-fi-like dimensions of artificial intelligence, you just have a thing that is going to democratize a lot of capabilities in a way that's going to put the money for those capabilities both a little bit back into the pockets of the people","speaker":"EZRA KLEIN","timecode":{"start":2732.94,"end":2750.42,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"who need them, and then a lot into the people who run the best A.I. rigs and is going to have a really weird geographically destabilizing effect.","speaker":"EZRA KLEIN","timecode":{"start":2750.42,"end":2759.66,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And that paradox of the internet both democratizing geography, and then concentrating wealth and capital in very small areas is, to me, a central challenge.","speaker":"EZRA KLEIN","timecode":{"start":2759.67,"end":2770.46,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Because if you get that wrong, if it goes too much in the concentration area, I think we're going to lose a lot of the political stability we need here.","speaker":"EZRA KLEIN","timecode":{"start":2770.46,"end":2779.1,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But you're more on top of these technological advances than I am.","speaker":"EZRA KLEIN","timecode":{"start":2779.1,"end":2782.04,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Do you think the trends there are going to play out differently than I'm worried they will?","speaker":"EZRA KLEIN","timecode":{"start":2782.04,"end":2786.3,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"First, yeah, it's not --","speaker":"PATRICK COLLISON","timecode":{"start":2786.31,"end":2788.07,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I don't think it's foreordained whether or not these are going to be centralized technologies.","speaker":"PATRICK COLLISON","timecode":{"start":2788.07,"end":2792.93,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I don't know.","speaker":"PATRICK COLLISON","timecode":{"start":2792.93,"end":2793.74,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And on the one hand, there's, I think, an obvious feature we can contemplate, where there are only three A.I. models, and they are rooted in the hegemons, the citadels of Silicon Valley technology, and we all are digital serfs who are subsistence-farming on their gains.","speaker":"PATRICK COLLISON","timecode":{"start":2793.74,"end":2813.15,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I think there's also a very plausible story where these technologies prove substantially less defensible than we might have expected, and where, instead, they have this enormously decentralizing effect.","speaker":"PATRICK COLLISON","timecode":{"start":2813.16,"end":2827.01,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Because otherwise, economies of scale that only large firms could benefit from can now be realized and pursued, even by massively smaller firms.","speaker":"PATRICK COLLISON","timecode":{"start":2827.01,"end":2838,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And if we look at the recent history of A.I. --","speaker":"PATRICK COLLISON","timecode":{"start":2838,"end":2841.881,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I don't think any clear story there, but it does feel to me that it has been more biased towards the second story than the first.","speaker":"PATRICK COLLISON","timecode":{"start":2841.881,"end":2850.17,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"There are now multiple companies with large language models.","speaker":"PATRICK COLLISON","timecode":{"start":2850.18,"end":2855.09,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"There are a number of very successful open-source A.I. efforts.","speaker":"PATRICK COLLISON","timecode":{"start":2855.09,"end":2860.37,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Actually, there was a really cool example from Replit, which is a service --","speaker":"PATRICK COLLISON","timecode":{"start":2860.37,"end":2865.89,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"it's a programming I.D. in the browser, used by kids learning to code, but also increasingly used by people who are pursuing serious programming.","speaker":"PATRICK COLLISON","timecode":{"start":2865.89,"end":2874.11,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And they recently released a GitHub copilot-like technology, where it will kind of autocomplete your code in the editor, and where you can do some pretty cool things.","speaker":"PATRICK COLLISON","timecode":{"start":2874.12,"end":2884.43,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Like, you can highlight a block of code and ask it to be explained, and it'll turn code into natural language, into English, and say, hey, here's what this code is doing.","speaker":"PATRICK COLLISON","timecode":{"start":2884.43,"end":2893.43,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Anyway, they wrote a blog post about how they built this, and they describe how it was built by one guy over the course of a couple of weeks.","speaker":"PATRICK COLLISON","timecode":{"start":2893.44,"end":2901.11,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And maybe that's only the case in the early days of this AI technology.","speaker":"PATRICK COLLISON","timecode":{"start":2901.11,"end":2905.83,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I mean, in early computer games, the first games were built by a single heroic person, and now, it's these gigantic studios and enormous CapEx budgets.","speaker":"PATRICK COLLISON","timecode":{"start":2905.83,"end":2914.37,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And so I think the fact that this is the case today doesn't mean that it will remain the case through time.","speaker":"PATRICK COLLISON","timecode":{"start":2914.38,"end":2919.11,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But my takeaway is that at least not foreordained that AI or any of these other technologies will be centralizing forces.","speaker":"PATRICK COLLISON","timecode":{"start":2919.11,"end":2926.25,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And then, the other thing to observe is that when we talk about these being centralizing, I think there's a question as to, do we look at it in relative or absolute terms?","speaker":"PATRICK COLLISON","timecode":{"start":2926.25,"end":2936,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And my contention would be that, both from a moral standpoint, but maybe more importantly from kind of a political-economy standpoint, what will matter is whether, on an absolute basis, people feel like they are realizing opportunities,","speaker":"PATRICK COLLISON","timecode":{"start":2936.01,"end":2951.753,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"their lives are improving, that things are getting better, that their kids will be in a better situation and so forth.","speaker":"PATRICK COLLISON","timecode":{"start":2951.753,"end":2956.67,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And exactly how much value is realized by the companies themselves doesn't actually matter that much, compared to that former question.","speaker":"PATRICK COLLISON","timecode":{"start":2956.67,"end":2966.18,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And whether A.W.S. or whether any of these organizations has super high or super low profit margins, I don't know is nearly as important as what is the actual effect on these communities and individuals across the society.","speaker":"PATRICK COLLISON","timecode":{"start":2966.19,"end":2981.83,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And so in as much as one means --","speaker":"PATRICK COLLISON","timecode":{"start":2981.83,"end":2984.55,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"by centralizing, one means a large share of the profits, I think it is probably a more useful framing to look at it instead in terms of absolutes, and in particular, the absolute surplus generated by the users.","speaker":"PATRICK COLLISON","timecode":{"start":2984.55,"end":2994.99,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"[MUSIC PLAYING]","speaker":"PATRICK COLLISON","timecode":{"start":2995,"end":3027.15,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"What have you come to believe about the relationship between progress and war?","speaker":"EZRA KLEIN","timecode":{"start":3027.15,"end":3030.9,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I am somewhat skeptical that war is as conducive to breakthroughs as we might intuitively conclude, or as is sometimes claimed.","speaker":"PATRICK COLLISON","timecode":{"start":3030.91,"end":3043.14,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"You're probably familiar with Alexander Field's work on the '30s here.","speaker":"PATRICK COLLISON","timecode":{"start":3043.14,"end":3047.05,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And his basic claim is, the productivity gains we often attribute to the Second World War in the U.S. --","speaker":"PATRICK COLLISON","timecode":{"start":3047.05,"end":3052.92,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"like, those foundations actually were laid in the '30s, and then the first half of the '40s were a period of decreasing productivity as we massively, inefficiently reallocated","speaker":"PATRICK COLLISON","timecode":{"start":3052.92,"end":3062.43,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"our economic resources for the purposes of winning the war, which was probably a good thing to do, but inefficient in narrow economic terms.","speaker":"PATRICK COLLISON","timecode":{"start":3062.43,"end":3068.62,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And he has a new book coming out, I think, next month, that sort of extends this argument into the '50s.","speaker":"PATRICK COLLISON","timecode":{"start":3068.63,"end":3074.1,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And as one takes stock of the scientific breakthroughs -- and so Stripe Press recently republished Vannevar Bush's memoir, where he takes stock of this.","speaker":"PATRICK COLLISON","timecode":{"start":3074.11,"end":3083.64,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And obviously, you have, say, the Manhattan Project, and that's a big deal, certainly.","speaker":"PATRICK COLLISON","timecode":{"start":3083.65,"end":3090.03,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But it doesn't feel to me that had the Manhattan Project not occurred, that peaceful development of nuclear technology would have been massively stymied.","speaker":"PATRICK COLLISON","timecode":{"start":3090.03,"end":3100.77,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Maybe it would have taken another 10 years, but it was already happening to some meaningful extent.","speaker":"PATRICK COLLISON","timecode":{"start":3100.77,"end":3105.85,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And then, as you take stock of all the other breakthroughs that took place in the U.S. during the Second World War, there were some meaningful stuff like blood plasma and blood transfusions.","speaker":"PATRICK COLLISON","timecode":{"start":3105.86,"end":3115.83,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"There was some significant breakthroughs there.","speaker":"PATRICK COLLISON","timecode":{"start":3115.83,"end":3118.2,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Some of the first antimalarial medications, radar, the proximity fuse, which I'm not sure is all that useful outside of military applications.","speaker":"PATRICK COLLISON","timecode":{"start":3118.2,"end":3127.41,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But by the time you get down to invention 6 on the list, I don't know that as you compare that list to, again, some counterfactual of what would otherwise have ensued, that it looks radically better as you take stock of the Cold War and the enormous fraction of our economic resources","speaker":"PATRICK COLLISON","timecode":{"start":3127.42,"end":3148.59,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"and human capital that were devoted towards us, that the gains necessarily look that impressive.","speaker":"PATRICK COLLISON","timecode":{"start":3148.59,"end":3153.835,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And so again, it's super hard to judge.","speaker":"PATRICK COLLISON","timecode":{"start":3153.835,"end":3155.46,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"You don't have proper controls and so on.","speaker":"PATRICK COLLISON","timecode":{"start":3155.46,"end":3157.168,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But I'm skeptical.","speaker":"PATRICK COLLISON","timecode":{"start":3157.168,"end":3159.065,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Let me take the other side.","speaker":"EZRA KLEIN","timecode":{"start":3159.065,"end":3160.69,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So there's a question of, during war, how much did we invent during World War II.","speaker":"EZRA KLEIN","timecode":{"start":3160.69,"end":3165.18,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And that's a question of how much the threat of war or the competition with an adversary ends up charging up innovation and convinces us to put resources, both in terms of people and in terms of money, and maybe in terms of institutions, into projects we wouldn't otherwise have done.","speaker":"EZRA KLEIN","timecode":{"start":3165.18,"end":3182.317,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I think there's an argument, at least, that we went to the moon because of the Soviet Union.","speaker":"EZRA KLEIN","timecode":{"start":3182.317,"end":3186.15,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"It would not have done that for some time.","speaker":"EZRA KLEIN","timecode":{"start":3186.15,"end":3187.9,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Probably would have eventually done it, but also, who knows?","speaker":"EZRA KLEIN","timecode":{"start":3187.9,"end":3190.98,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"As Derek Thompson, who I'm working on a lot of these ideas with, likes to point out, the Apollo Project was unpopular.","speaker":"EZRA KLEIN","timecode":{"start":3190.99,"end":3197.34,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"It was not something that commanded wide popular support.","speaker":"EZRA KLEIN","timecode":{"start":3197.34,"end":3200.85,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Even now, if you look at the CHIPS Act that passed, it passed, with all that spending on semiconductor research and other kinds of next-generation technologies, under the framework of, let's compete more effectively with China.","speaker":"EZRA KLEIN","timecode":{"start":3200.86,"end":3214.57,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"If you look at all the things Darpa has done or been part of, the fact that \"defense\" is the first word in the Darpa acronym, I think, is meaningful.","speaker":"EZRA KLEIN","timecode":{"start":3214.57,"end":3222.63,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"There's something about what threat persuades societies to do, and persuades them to do technologically or what risks it allows otherwise-more-cautious governments to take, or what failures they could justify that allows them to have big successes.","speaker":"EZRA KLEIN","timecode":{"start":3222.64,"end":3238.26,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Something there doesn't seem to small to me.","speaker":"EZRA KLEIN","timecode":{"start":3238.26,"end":3240.84,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And maybe it's my political side, where I so often see scientific funding justified in Congress in terms of countries we're competing with or are adversaries with.","speaker":"EZRA KLEIN","timecode":{"start":3240.85,"end":3251.28,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I see what the defense industry can do that other institutions cannot, because they don't get a lot of political blowback.","speaker":"EZRA KLEIN","timecode":{"start":3251.28,"end":3257.592,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But I don't know.","speaker":"EZRA KLEIN","timecode":{"start":3257.592,"end":3258.3,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I worry a little bit about how much we seem to need the threat of another to accelerate things.","speaker":"EZRA KLEIN","timecode":{"start":3258.31,"end":3264.48,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And in a small way, maybe, we see what the pandemic -- where we were willing to move much, much quicker on things like mRNA technology than I think we would have outside of it.","speaker":"EZRA KLEIN","timecode":{"start":3264.48,"end":3271.932,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Yeah.","speaker":"PATRICK COLLISON","timecode":{"start":3271.932,"end":3272.89,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So I think it's certainly true that the crisis can cause the discontinuous shifts that have large effects, which in your example, say, are probably super beneficial.","speaker":"PATRICK COLLISON","timecode":{"start":3272.89,"end":3286.66,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I don't know.","speaker":"PATRICK COLLISON","timecode":{"start":3286.66,"end":3288.49,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"If you take Darpa as an example, it started as Arpa, as a more open-ended research institution and set of programs, and then with the Vietnam War, had the D pretended to it.","speaker":"PATRICK COLLISON","timecode":{"start":3288.49,"end":3305.53,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And we decided, in the face of threat, to make it more applied, to take more seriously its translational and kind of, quote unquote, \"competition-oriented mandate.\"","speaker":"PATRICK COLLISON","timecode":{"start":3305.54,"end":3317.66,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I think that was bad for Darpa.","speaker":"PATRICK COLLISON","timecode":{"start":3317.66,"end":3319.39,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And the internet, which arose under Arpa --","speaker":"PATRICK COLLISON","timecode":{"start":3319.39,"end":3323.77,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"it's hard to think of innovations of similar magnitudes that then occurred in then-Darpa's subsequent, say, two decades.","speaker":"PATRICK COLLISON","timecode":{"start":3323.77,"end":3332.62,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"If you take, say, U.S. science in general, the war --","speaker":"PATRICK COLLISON","timecode":{"start":3332.63,"end":3336.25,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"the Second World War --","speaker":"PATRICK COLLISON","timecode":{"start":3336.25,"end":3337.36,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"to some extent, the first, but much more so the second --","speaker":"PATRICK COLLISON","timecode":{"start":3337.36,"end":3339.79,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"precipitated an enormous centralization of U.S. science in its aftermath.","speaker":"PATRICK COLLISON","timecode":{"start":3339.79,"end":3344.86,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Because we really marshaled together all of the -- or a significant fraction of the scientific capacity of the U.S. in service of the war effort.","speaker":"PATRICK COLLISON","timecode":{"start":3344.86,"end":3354.01,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"For, example the 50 percent overhead, the fraction of government grants that goes to universities -- that was chosen in the early days of the coordination of the war effort, and has now become a kind of a pillar of academic and research funding in the U.S. And in the aftermath of the war,","speaker":"PATRICK COLLISON","timecode":{"start":3354.02,"end":3370.475,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"we sort have this question of OK, we've kind of pulled everything together.","speaker":"PATRICK COLLISON","timecode":{"start":3370.475,"end":3373.6,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Now, what do we do?","speaker":"PATRICK COLLISON","timecode":{"start":3373.6,"end":3374.77,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And that became, in various ways, the N.I.H. and the N.S.F. and so on.","speaker":"PATRICK COLLISON","timecode":{"start":3374.78,"end":3379.75,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I mean, the N.I.H. predated it, but the growth of the N.I.H. really occurred after the war.","speaker":"PATRICK COLLISON","timecode":{"start":3379.75,"end":3383.8,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And the federal government, shortly thereafter, for the first time, became the majority funder of US science.","speaker":"PATRICK COLLISON","timecode":{"start":3383.8,"end":3390.01,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And all that centralization -- and I mean, you pointed out the benefits of variety and of experimentation and of heterogeneity, and having some degree of institutional and structural diversity and so on, I totally agree with all of that.","speaker":"PATRICK COLLISON","timecode":{"start":3390.01,"end":3401.78,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I think all of that was very meaningfully curtailed by, again, the aftershocks of some of the threats that we faced during the war.","speaker":"PATRICK COLLISON","timecode":{"start":3401.79,"end":3408.55,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And if you think about the things that we're maybe happiest about having happened -- the founding of the major new U.S. research universities in the latter parts of the 19th century or the revolution in health care and kind of medical practice that first happened at Johns Hopkins,","speaker":"PATRICK COLLISON","timecode":{"start":3408.55,"end":3425.83,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"and then kind of codified in the Flexner Report, or the great industrial research labs of Bell and Park and so on -- or excuse me --","speaker":"PATRICK COLLISON","timecode":{"start":3425.83,"end":3433.51,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Xerox -- they didn't obviously come from a place of fear or a threat.","speaker":"PATRICK COLLISON","timecode":{"start":3433.51,"end":3438.31,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"They came from a place of hope and optimism and opportunity.","speaker":"PATRICK COLLISON","timecode":{"start":3438.32,"end":3442.39,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And maybe there are some inventions that you're more likely to get to from some of these external pressures.","speaker":"PATRICK COLLISON","timecode":{"start":3442.39,"end":3449.68,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But yeah, if you gave me a dial, and I can kind of turn up or down the threat or fear index of society, it's not super obvious to me that one would want to turn it up if what one cared about was the aggregate rate of progress.","speaker":"PATRICK COLLISON","timecode":{"start":3449.68,"end":3463.885,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"That's a good bridge, I think, to the question of institutions.","speaker":"EZRA KLEIN","timecode":{"start":3463.885,"end":3467.01,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I take one of the main concerns of yours, of progress studies, as being around institutional slowdown.","speaker":"EZRA KLEIN","timecode":{"start":3467.01,"end":3475.68,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"You have this idea that we don't meta-maintain institutions very well.","speaker":"EZRA KLEIN","timecode":{"start":3475.68,"end":3478.8,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"They start in one place, and then over time, they crust over, and we don't really know what to do with that.","speaker":"EZRA KLEIN","timecode":{"start":3478.81,"end":3484,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Give me a little bit of your thinking there.","speaker":"EZRA KLEIN","timecode":{"start":3484,"end":3487.41,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I think institutions, the cultures they instill and act as kind of coordination points and training sites for --","speaker":"PATRICK COLLISON","timecode":{"start":3487.42,"end":3498.17,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"those of enormous consequence --","speaker":"PATRICK COLLISON","timecode":{"start":3498.17,"end":3499.82,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I think much of the success of the U.S. and of various other Western countries has, in substantial part, been attributable to successful institutions.","speaker":"PATRICK COLLISON","timecode":{"start":3499.82,"end":3512.33,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Most people would accept, I think, that there is, to some extent, consistent trends that tend to happen with institutions through time.","speaker":"PATRICK COLLISON","timecode":{"start":3512.33,"end":3523.67,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Just maybe most basically, the problem that gives rise to an institution in the first place is probably a pretty real and significant problem.","speaker":"PATRICK COLLISON","timecode":{"start":3523.68,"end":3533.72,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"No one would have taken the time to found the institution if it wasn't.","speaker":"PATRICK COLLISON","timecode":{"start":3533.72,"end":3537.65,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And there can be some degree of drift there, where we don't necessarily decommission the institution once the problem has subsided or abated.","speaker":"PATRICK COLLISON","timecode":{"start":3537.65,"end":3545.39,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And then, you tend to attract a certain kind of person in the early days of an institution -- people who are slightly less status and reputation and procedure-oriented, because a new institution almost never has that.","speaker":"PATRICK COLLISON","timecode":{"start":3545.4,"end":3555.47,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And then, through time, the sort of collective or the mission-oriented incentives of the institution can kind of drift somewhat from the individual incentives that particular people are subject to.","speaker":"PATRICK COLLISON","timecode":{"start":3555.47,"end":3565.1,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I think all this stuff exists.","speaker":"PATRICK COLLISON","timecode":{"start":3565.11,"end":3566.78,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And the thing that I observe, or that I just find myself thinking about is, we've had eras of institution formation in the U.S. It has not been kind of a constant rate through time.","speaker":"PATRICK COLLISON","timecode":{"start":3566.78,"end":3577.58,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And the New Deal maybe, and say, the 30 years afterwards, and the Great Society -- we bookend it with those start and endpoints.","speaker":"PATRICK COLLISON","timecode":{"start":3577.58,"end":3586.28,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"That was a period of tremendously active institution construction and formation in the U.S., Darpa being -- or Arpa originally being a good example, and indeed, NASA.","speaker":"PATRICK COLLISON","timecode":{"start":3586.29,"end":3597.26,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I guess I find myself wondering, one, if we didn't have any of these institutions -- and I'm not saying we should get rid of them.","speaker":"PATRICK COLLISON","timecode":{"start":3597.26,"end":3603.12,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But if we didn't have them, what institutions would we found today, first, and how high in the list would NASA be, for example?","speaker":"PATRICK COLLISON","timecode":{"start":3603.12,"end":3611.24,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And then, secondly, in as much as we accept that some of these institutional dynamics exist, like the fact that sclerosis as an emergent property arises, what do we do about that?","speaker":"PATRICK COLLISON","timecode":{"start":3611.25,"end":3625.89,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And lots of people have told us it's pretty --","speaker":"PATRICK COLLISON","timecode":{"start":3625.89,"end":3628.61,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"doesn't need a lot of teasing apart to see it as one compares NASA and SpaceX and the respective budgets, and the respective achievements, and so forth, I think it's hard to not at least wonder about their respective efficiencies.","speaker":"PATRICK COLLISON","timecode":{"start":3628.61,"end":3645.68,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And say, if society could only have SpaceX or NASA, which one would we choose, and what should we conclude from that, and to what extent do those phenomena generalize elsewhere?","speaker":"PATRICK COLLISON","timecode":{"start":3645.69,"end":3654.063,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I don't have answers to these questions.","speaker":"PATRICK COLLISON","timecode":{"start":3654.063,"end":3655.73,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But I find that in the political discourse -- not that anybody is celebrating that, but in the discourse, it's very easy to get, I think, very wrapped up in questions of optimal funding levels, and should this number be 10 percent or 50 percent or higher or whatever, whereas to me,","speaker":"PATRICK COLLISON","timecode":{"start":3655.73,"end":3672.14,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"a lot of our satisfaction with the outcomes seems to hinge on deeper questions about the nature of the institution.","speaker":"PATRICK COLLISON","timecode":{"start":3672.14,"end":3677.58,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I don't know that the problem or benefit, or anything good or bad about NASA is attributable to the budget, per se.","speaker":"PATRICK COLLISON","timecode":{"start":3677.59,"end":3683.96,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"It seems more, kind of, resonant in some of these deeper cultural questions.","speaker":"PATRICK COLLISON","timecode":{"start":3683.96,"end":3688.85,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And then, in the recent pandemic, or in the --","speaker":"PATRICK COLLISON","timecode":{"start":3688.85,"end":3691.638,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I don't know.","speaker":"PATRICK COLLISON","timecode":{"start":3691.638,"end":3692.18,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I was going to say, ongoing pandemic.","speaker":"PATRICK COLLISON","timecode":{"start":3692.18,"end":3693.722,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But I guess as of two days ago, with the President's verdict, it is now over.","speaker":"PATRICK COLLISON","timecode":{"start":3693.722,"end":3697.623,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"It's over.","speaker":"EZRA KLEIN","timecode":{"start":3697.623,"end":3698.54,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Congratulations, everybody.","speaker":"EZRA KLEIN","timecode":{"start":3698.54,"end":3699.59,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Exactly.","speaker":"PATRICK COLLISON","timecode":{"start":3699.6,"end":3700.673,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But anyway, I think that was maybe a vivid demonstration of many of these dynamics, where I don't know this any of the story about the institutional response to the pandemic should be primarily one of funding.","speaker":"PATRICK COLLISON","timecode":{"start":3700.673,"end":3711.81,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I think it's much more about the dispositions and the attitudes and the cultural biases of entities like the N.I.H. and the F.D.A. and the C.D.C.","speaker":"PATRICK COLLISON","timecode":{"start":3711.81,"end":3720.42,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I find the NASA SpaceX example an interesting and provocative one.","speaker":"EZRA KLEIN","timecode":{"start":3720.43,"end":3723.78,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Because on the one hand, I think what you're saying is completely true.","speaker":"EZRA KLEIN","timecode":{"start":3723.78,"end":3727.56,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And where a lot of the NASA programs and projects have gone in recent decades, is just --","speaker":"EZRA KLEIN","timecode":{"start":3727.56,"end":3733.26,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"it's sad.","speaker":"EZRA KLEIN","timecode":{"start":3733.26,"end":3734.37,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"It's just a sad story.","speaker":"EZRA KLEIN","timecode":{"start":3734.37,"end":3736.38,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And on the other hand, the idea that you --","speaker":"EZRA KLEIN","timecode":{"start":3736.39,"end":3738.21,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"the thought experiment of choosing between NASA and SpaceX --","speaker":"EZRA KLEIN","timecode":{"start":3738.21,"end":3741.57,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"the thing that it immediately asks is, well, you can't.","speaker":"EZRA KLEIN","timecode":{"start":3741.57,"end":3746.34,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Because without NASA, there is no SpaceX.","speaker":"EZRA KLEIN","timecode":{"start":3746.34,"end":3749.54,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And one way the private sector handles a lot of these questions --","speaker":"EZRA KLEIN","timecode":{"start":3749.54,"end":3752.29,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I mean, I'm always struck by how much of the way biotech research works is that big pharmaceutical companies acquire small biotech firms that have made a breakthrough or have come up with a very promising candidate.","speaker":"EZRA KLEIN","timecode":{"start":3752.29,"end":3764.25,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"This is kind of an accepted thing that the big companies -- they do a fair amount of research, but a major, major innovation transmission there is small groups do more, quicker, and they're just going to buy them.","speaker":"EZRA KLEIN","timecode":{"start":3764.25,"end":3775.86,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And the NASA SpaceX example has a little bit of that dynamic to it, although with a different mechanism of financing.","speaker":"EZRA KLEIN","timecode":{"start":3775.86,"end":3783.342,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I don't know.","speaker":"EZRA KLEIN","timecode":{"start":3783.342,"end":3784.05,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I wonder if there aren't deeper lessons there.","speaker":"EZRA KLEIN","timecode":{"start":3784.05,"end":3786.21,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Yeah, I don't mean here in the NASA example -- like, I don't think reducing it to a simple binary of this-or-that is correct.","speaker":"PATRICK COLLISON","timecode":{"start":3786.22,"end":3793.2,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"It's more, what should we make of the differences in these two organizations?","speaker":"PATRICK COLLISON","timecode":{"start":3793.2,"end":3797.82,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And given those observations or beliefs, what do we then think an efficient outcome might look like?","speaker":"PATRICK COLLISON","timecode":{"start":3797.82,"end":3804.24,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And do we think that where we are today -- this prevailing status quo -- is optimal?","speaker":"PATRICK COLLISON","timecode":{"start":3804.25,"end":3808.32,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Or are there other things we can do better?","speaker":"PATRICK COLLISON","timecode":{"start":3808.32,"end":3810.21,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And maybe an important thing to say within all of this is, to the extent that these are all kind of inevitably determined outcomes, maybe it doesn't really matter if we think things would be better or worse.","speaker":"PATRICK COLLISON","timecode":{"start":3810.21,"end":3821.333,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"We're going to end up in the same place, regardless.","speaker":"PATRICK COLLISON","timecode":{"start":3821.333,"end":3823.5,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But I think for all of these, it's super contingent.","speaker":"PATRICK COLLISON","timecode":{"start":3823.5,"end":3826.29,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And various aspects of both funding decisions and, kind of, the precepts and methodologies of the N.I.H., how we design I.P. law, how we regulate and require and run clinical trials --","speaker":"PATRICK COLLISON","timecode":{"start":3826.29,"end":3841.98,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"there are tons of individual contingent decisions that we kind of have collectively made that give rise to the biotech and to the pharma ecosystem.","speaker":"PATRICK COLLISON","timecode":{"start":3841.98,"end":3851.8,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And certainly, in the case of space, you know, like, it doesn't have to be this way other.","speaker":"PATRICK COLLISON","timecode":{"start":3851.81,"end":3856.05,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Universes, no pun intended, are possible.","speaker":"PATRICK COLLISON","timecode":{"start":3856.05,"end":3858.15,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I think perhaps the thing that people underappreciated with science in the U.S. is, it has been very different in the not-too-distant past.","speaker":"PATRICK COLLISON","timecode":{"start":3858.15,"end":3867.78,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Peer review is a relatively recent invention.","speaker":"PATRICK COLLISON","timecode":{"start":3867.79,"end":3870.72,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Modern journals are a relatively recent invention.","speaker":"PATRICK COLLISON","timecode":{"start":3870.72,"end":3873.42,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"As I mentioned, the federal government being the primary funder of basic research is a relatively recent invention.","speaker":"PATRICK COLLISON","timecode":{"start":3873.42,"end":3879.78,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And molecular biology was, in significant part, a thesis by Warren Weaver at the Rockefeller Foundation.","speaker":"PATRICK COLLISON","timecode":{"start":3879.79,"end":3888,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"There's a thing here, and we should aggressively pursue it.","speaker":"PATRICK COLLISON","timecode":{"start":3888,"end":3891.87,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But importantly, it was not --","speaker":"PATRICK COLLISON","timecode":{"start":3891.87,"end":3894.81,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"it required an institution, an organization, that was not part of the standard apparatus, for want of a better term.","speaker":"PATRICK COLLISON","timecode":{"start":3894.81,"end":3902.43,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And the Broad Institute, over the last 25 years, has been enormously successful in the field of genomics and functional genomics and CRISPR, et cetera.","speaker":"PATRICK COLLISON","timecode":{"start":3902.44,"end":3912.48,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And the Broad Institute is itself a kind of structural innovation, breaking somewhat from the more traditional prevailing university model.","speaker":"PATRICK COLLISON","timecode":{"start":3912.48,"end":3922.42,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And so I think the fact that so many of our successes are associated with some degree of structural and institutional change should be somewhat thought-provoking for us.","speaker":"PATRICK COLLISON","timecode":{"start":3922.42,"end":3932.07,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"You've been trying to work in the space of institution-building here, too.","speaker":"EZRA KLEIN","timecode":{"start":3932.08,"end":3935.94,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I want to talk about Fast Grants and about Arc a little bit.","speaker":"EZRA KLEIN","timecode":{"start":3935.94,"end":3938.53,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So let's begin with Fast Grants.","speaker":"EZRA KLEIN","timecode":{"start":3938.53,"end":3940.35,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"What is it, and what has it taught you?","speaker":"EZRA KLEIN","timecode":{"start":3940.35,"end":3942.96,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Well, it's mostly \"what was it.\"","speaker":"PATRICK COLLISON","timecode":{"start":3942.97,"end":3945.18,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"In the early days of the pandemic --","speaker":"PATRICK COLLISON","timecode":{"start":3945.18,"end":3948.16,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"well, I should preface all of this by saying --","speaker":"PATRICK COLLISON","timecode":{"start":3948.16,"end":3950.26,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"well, I'll reaffirm my preface that I don't know, to every question.","speaker":"PATRICK COLLISON","timecode":{"start":3950.26,"end":3953.093,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But more importantly here, I will say, my now-wife is herself a scientist.","speaker":"PATRICK COLLISON","timecode":{"start":3953.093,"end":3958.26,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"We've known each other since we were teenagers.","speaker":"PATRICK COLLISON","timecode":{"start":3958.26,"end":3960.93,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"We spend a lot of time talking about science in various forms.","speaker":"PATRICK COLLISON","timecode":{"start":3960.93,"end":3963.643,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"You met --","speaker":"EZRA KLEIN","timecode":{"start":3963.643,"end":3964.56,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"am I allowed to say this?","speaker":"EZRA KLEIN","timecode":{"start":3964.56,"end":3965.602,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"You met at a science competition.","speaker":"EZRA KLEIN","timecode":{"start":3965.602,"end":3967.838,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"That is true.","speaker":"PATRICK COLLISON","timecode":{"start":3967.838,"end":3969.13,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"We met at a science competition, 100 teenagers, and --","speaker":"PATRICK COLLISON","timecode":{"start":3969.13,"end":3972.472,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And she beat you.","speaker":"EZRA KLEIN","timecode":{"start":3972.472,"end":3973.68,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And yes.","speaker":"PATRICK COLLISON","timecode":{"start":3973.69,"end":3974.787,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I was the runner-up, and she was the winner.","speaker":"PATRICK COLLISON","timecode":{"start":3974.787,"end":3976.62,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I had created a programming language and a new dialect of lisp, and she had created a new treatment for urinary tract infections.","speaker":"PATRICK COLLISON","timecode":{"start":3976.62,"end":3984.36,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And so I really don't envy the judges for having to figure out what framework one should use to make all these comparisons and lots of other people.","speaker":"PATRICK COLLISON","timecode":{"start":3984.36,"end":3992.018,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"You sound a little bitter, man.","speaker":"EZRA KLEIN","timecode":{"start":3992.018,"end":3993.81,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"[CHUCKLES] I was gonna say, but no, we can all agree this the correct outcomes ensued.","speaker":"PATRICK COLLISON","timecode":{"start":3993.82,"end":3998.885,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Anyway, so we were living together in March of 2020, holed up.","speaker":"PATRICK COLLISON","timecode":{"start":3998.885,"end":4003.65,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And a number of her friends and colleagues were unsurprisingly with, I guess, a large fraction of all biology scientists, were trying to urgently repurpose their work to figure out, well, could they do something that would be somehow benefit to accelerating the end of the pandemic?","speaker":"PATRICK COLLISON","timecode":{"start":4003.65,"end":4021.82,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And by early April, so a couple of weeks into lockdown, when it was becoming apparent and striking to us, which was it is difficult for these people to get funding for their work.","speaker":"PATRICK COLLISON","timecode":{"start":4021.83,"end":4033.912,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And that might sound a bit, kind of, surprising, because you think, well, don't they have some degree of money already?","speaker":"PATRICK COLLISON","timecode":{"start":4033.912,"end":4038.87,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And couldn't they just go and just spend that?","speaker":"PATRICK COLLISON","timecode":{"start":4038.87,"end":4040.87,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But there are, obviously, significant rules around and restrictions around that which one can do with one's grant money.","speaker":"PATRICK COLLISON","timecode":{"start":4040.88,"end":4047.59,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"This is money provided by the government for a purpose.","speaker":"PATRICK COLLISON","timecode":{"start":4047.59,"end":4050.51,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And so it's not like you can go and readily spend it on something totally unrelated.","speaker":"PATRICK COLLISON","timecode":{"start":4050.51,"end":4054.79,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And the money is administered by the university, and so you have to go through their proper procurement processes.","speaker":"PATRICK COLLISON","timecode":{"start":4054.8,"end":4059.56,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Point is, lots of restrictions on scientists' pecuniary ability to suddenly repurpose the research agendas.","speaker":"PATRICK COLLISON","timecode":{"start":4059.56,"end":4066.25,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And we kind of thought, well --","speaker":"PATRICK COLLISON","timecode":{"start":4066.25,"end":4068.29,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"we assume maybe in the early weeks, that presumably various bodies --","speaker":"PATRICK COLLISON","timecode":{"start":4068.29,"end":4072.22,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I don't know who -- some kind of amorphous other, some combination of C.D.C., F.D.A., N.I.H., philanthropies -- whatever.","speaker":"PATRICK COLLISON","timecode":{"start":4072.22,"end":4077.65,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Somebody will come along and just give these scientists the obvious money that society clearly should, so they can go, and they can pursue these programs.","speaker":"PATRICK COLLISON","timecode":{"start":4077.66,"end":4084.643,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Didn't seem to be happening.","speaker":"PATRICK COLLISON","timecode":{"start":4084.643,"end":4085.81,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I mean, to be fair, I don't want to give us too much credit.","speaker":"PATRICK COLLISON","timecode":{"start":4085.81,"end":4088.31,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Various people were doing things right off the bat in various different places, but we just personally knew of lots of specific examples of really good scientists who were unable to make progress of their work to the extent that they would like.","speaker":"PATRICK COLLISON","timecode":{"start":4088.31,"end":4099.109,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So we tried to set up what we thought would be a pretty small initiative, and called Fast Grants.","speaker":"PATRICK COLLISON","timecode":{"start":4099.109,"end":4103.75,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"The basic idea would be, you send us some kind of proposal.","speaker":"PATRICK COLLISON","timecode":{"start":4103.76,"end":4106.689,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And initially, within 48 hours, you would get a funding decision and either receive money or not.","speaker":"PATRICK COLLISON","timecode":{"start":4106.689,"end":4112.455,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"We started out with a pretty small amount of money.","speaker":"PATRICK COLLISON","timecode":{"start":4112.455,"end":4114.58,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"The initial donors -- we were among them, but there were a number --","speaker":"PATRICK COLLISON","timecode":{"start":4114.59,"end":4117.413,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"contributed, best I recall, about $10 million.","speaker":"PATRICK COLLISON","timecode":{"start":4117.413,"end":4120.37,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Launched the website early April 2020.","speaker":"PATRICK COLLISON","timecode":{"start":4120.37,"end":4122.71,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Quickly inundated with, I think, four and a half thousand applications, which, given our promised 48-hour turnaround, was somewhat challenging.","speaker":"PATRICK COLLISON","timecode":{"start":4122.71,"end":4131.8,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I should say this was myself.","speaker":"PATRICK COLLISON","timecode":{"start":4131.81,"end":4133.24,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"This was Silvana, my wife, and this was Tyler Cohen.","speaker":"PATRICK COLLISON","timecode":{"start":4133.24,"end":4135.609,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So we had an immediate question as to, how do we actually run a philanthropic endeavor?","speaker":"PATRICK COLLISON","timecode":{"start":4135.609,"end":4139.84,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And how do we stand it up in very short order?","speaker":"PATRICK COLLISON","timecode":{"start":4139.84,"end":4141.76,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And he, through Mercatus and through Emergent Ventures, had some experience of very efficient and somewhat-scaled grant-giving.","speaker":"PATRICK COLLISON","timecode":{"start":4141.76,"end":4147.97,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And so the three of us worked together to put it together over the course of a week or so.","speaker":"PATRICK COLLISON","timecode":{"start":4147.97,"end":4151.72,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"We proceeded over the course of, roughly speaking, the next year, slightly more, to make about 200 grants, eventually dispersing almost --","speaker":"PATRICK COLLISON","timecode":{"start":4151.72,"end":4161.17,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"or slightly over, actually -- $50 million in total, to universities around the world, though primarily in the U.S.","speaker":"PATRICK COLLISON","timecode":{"start":4161.17,"end":4167.62,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And you ask, kind of, what did we learn?","speaker":"PATRICK COLLISON","timecode":{"start":4167.63,"end":4169.93,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"A big surprise was how slowly other parts of the establishment mobilized.","speaker":"PATRICK COLLISON","timecode":{"start":4169.93,"end":4176.29,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And various of the projects we funded or the labs we funded and so on -- they've gone on to now do -- none of them were directly implicated in the vaccine research project that ended up yielding so much fruit.","speaker":"PATRICK COLLISON","timecode":{"start":4176.29,"end":4187.842,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So again, I don't want to give Fast Grants too much credit.","speaker":"PATRICK COLLISON","timecode":{"start":4187.842,"end":4190.3,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Eventually, the thing that really mattered, we had nothing to do with.","speaker":"PATRICK COLLISON","timecode":{"start":4190.3,"end":4193.217,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But versus the projects, things like Saliva Direct, which was in the summer an early discovery that saliva tests work basically as well as the nasopharyngeal swabs we were all being subject to, or various discoveries around possible therapeutics, some of which are --","speaker":"PATRICK COLLISON","timecode":{"start":4193.217,"end":4208.93,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"still continue to go through clinical trials, and may still turn out to matter to a significant extent.","speaker":"PATRICK COLLISON","timecode":{"start":4208.93,"end":4213.31,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And that 500 people are still dying in the U.S. per day from Covid, and --","speaker":"PATRICK COLLISON","timecode":{"start":4213.31,"end":4216.49,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"despite the existence of the vaccines and so on.","speaker":"PATRICK COLLISON","timecode":{"start":4216.49,"end":4218.49,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So anyway, various discoveries ensued that I think will prove to be important.","speaker":"PATRICK COLLISON","timecode":{"start":4218.5,"end":4222.11,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And the second thing we learned, which is not really related to Covid or the pandemic, but has certainly been significant for us, is --","speaker":"PATRICK COLLISON","timecode":{"start":4222.11,"end":4230.89,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"it just got us thinking more deeply and broadly about the questions of, how do scientists choose what to do?","speaker":"PATRICK COLLISON","timecode":{"start":4230.89,"end":4237.28,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And what are the constraints they're subject to as a practical and applied matter?","speaker":"PATRICK COLLISON","timecode":{"start":4237.28,"end":4243.1,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And this gets back to all this discussion about both culture and institutions.","speaker":"PATRICK COLLISON","timecode":{"start":4243.11,"end":4246.64,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And towards the end of Fast grants, we ran a survey of the grant recipients.","speaker":"PATRICK COLLISON","timecode":{"start":4246.64,"end":4251.5,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And these are essentially all people who don't normally -- certainly don't normally work on Covid.","speaker":"PATRICK COLLISON","timecode":{"start":4251.5,"end":4255.85,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Covid didn't exist.","speaker":"PATRICK COLLISON","timecode":{"start":4255.85,"end":4257.023,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But they don't even normally work on viruses, for the most part.","speaker":"PATRICK COLLISON","timecode":{"start":4257.023,"end":4259.69,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"These are basically kind of broadly drawn as a cross section across biology.","speaker":"PATRICK COLLISON","timecode":{"start":4259.69,"end":4264.49,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And we just asked them, as a general matter in your regular research, if you could spend your grant money however you want, how much would you change your research agenda?","speaker":"PATRICK COLLISON","timecode":{"start":4264.49,"end":4274.963,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So not an increase in the funding level, which tends to be what we discuss in as much as we're discussing science policy across society.","speaker":"PATRICK COLLISON","timecode":{"start":4274.963,"end":4280.63,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But much more specifically and narrowly, if you had complete autonomy in how you spend whatever grant money you're getting, how much of your research agenda would change?","speaker":"PATRICK COLLISON","timecode":{"start":4280.63,"end":4290.11,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And our intuition was that maybe a third of people would like to be doing something meaningfully different to what they actually are.","speaker":"PATRICK COLLISON","timecode":{"start":4290.11,"end":4296.89,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But of these scientists, and these are really good scientists, four out of five told us that they would change their research agendas, quote, \"a lot.\"","speaker":"PATRICK COLLISON","timecode":{"start":4296.9,"end":4306.025,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"We gave them three options.","speaker":"PATRICK COLLISON","timecode":{"start":4306.025,"end":4307.15,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Not much, or not at all, a little, and then a lot.","speaker":"PATRICK COLLISON","timecode":{"start":4307.15,"end":4309.64,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Four out of five chose the maximum option on our survey.","speaker":"PATRICK COLLISON","timecode":{"start":4309.64,"end":4314.228,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So I just find this incredibly thought-provoking.","speaker":"PATRICK COLLISON","timecode":{"start":4314.228,"end":4316.27,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Basically, we seem to be in a situation where most of our top scientists aren't doing what they think would be best for them to do.","speaker":"PATRICK COLLISON","timecode":{"start":4316.28,"end":4323.94,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And we could say, no, our various committees and governing bodies and decision-making apparatus and so on, they know better.","speaker":"PATRICK COLLISON","timecode":{"start":4323.94,"end":4331.28,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I'm not saying it would be completely unreasonable for one to maintain that.","speaker":"PATRICK COLLISON","timecode":{"start":4331.28,"end":4336.27,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But that would seem to be a very central question about the construction of our scientific apparatus.","speaker":"PATRICK COLLISON","timecode":{"start":4336.27,"end":4342.178,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I think that should give us some pause.","speaker":"PATRICK COLLISON","timecode":{"start":4342.178,"end":4343.97,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"There are a couple things there.","speaker":"EZRA KLEIN","timecode":{"start":4343.98,"end":4345.803,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"One is that it is a consistent observation I have learning about new areas that there is a way we're taught the thing works, or people think the thing works, and there's this huge middle layer.","speaker":"EZRA KLEIN","timecode":{"start":4345.803,"end":4357.09,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Right?","speaker":"EZRA KLEIN","timecode":{"start":4357.09,"end":4357.59,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So in politics, which I know very well, and legislation, you have the \"Schoolhouse Rock\" version of how a bill becomes a law.","speaker":"EZRA KLEIN","timecode":{"start":4357.59,"end":4363.65,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And then it's, like, a filibuster is how a bill becomes a law or does not become a law.","speaker":"EZRA KLEIN","timecode":{"start":4363.65,"end":4368.33,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"We were talking about drug innovation earlier.","speaker":"EZRA KLEIN","timecode":{"start":4368.34,"end":4370.73,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I think the folk way people think it works is we make a discovery about a drug, and then, like, we make a drug out of it after some tests.","speaker":"EZRA KLEIN","timecode":{"start":4370.73,"end":4376.76,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But you talk to people who work on pharmaceuticals and just clinical trials.","speaker":"EZRA KLEIN","timecode":{"start":4376.76,"end":4381.53,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And in science --","speaker":"EZRA KLEIN","timecode":{"start":4381.54,"end":4382.61,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I think if you had asked me as a high schooler, had some science classes, I'd have told you something about the scientific method.","speaker":"EZRA KLEIN","timecode":{"start":4382.61,"end":4389.5,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And then you talk to a scientist, and it's grants.","speaker":"EZRA KLEIN","timecode":{"start":4389.5,"end":4392.39,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Like, grants are how science works.","speaker":"EZRA KLEIN","timecode":{"start":4392.39,"end":4394.28,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Grants are the middle layer between -- you are a scientist, and you can do some science.","speaker":"EZRA KLEIN","timecode":{"start":4394.28,"end":4399.77,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And grants are how the N.S.F. and the N.I.H. work.","speaker":"EZRA KLEIN","timecode":{"start":4399.77,"end":4403.04,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"They're how a lot of the universities work.","speaker":"EZRA KLEIN","timecode":{"start":4403.04,"end":4404.84,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"There's fund-raising.","speaker":"EZRA KLEIN","timecode":{"start":4404.84,"end":4405.715,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I mean, there are different ways that it happens.","speaker":"EZRA KLEIN","timecode":{"start":4405.715,"end":4407.99,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"To make the question of \"Are we doing science well?\"","speaker":"EZRA KLEIN","timecode":{"start":4407.99,"end":4410.81,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"a little bit more precise, I think one version of that question is, \"Are we doing grants well?\"","speaker":"EZRA KLEIN","timecode":{"start":4410.81,"end":4416.66,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I think that question is more tractable.","speaker":"EZRA KLEIN","timecode":{"start":4416.66,"end":4418.843,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"People don't feel as defensive about it.","speaker":"EZRA KLEIN","timecode":{"start":4418.843,"end":4420.51,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But I've talked to a lot of scientists in the course of my work.","speaker":"EZRA KLEIN","timecode":{"start":4420.52,"end":4424.22,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I've covered health care for my entire career.","speaker":"EZRA KLEIN","timecode":{"start":4424.22,"end":4426.45,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I don't know any who think we're doing grants well.","speaker":"EZRA KLEIN","timecode":{"start":4426.45,"end":4428.99,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I don't know any who will not complain to you for hours.","speaker":"EZRA KLEIN","timecode":{"start":4428.99,"end":4431.42,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And they may be wrong.","speaker":"EZRA KLEIN","timecode":{"start":4431.43,"end":4433.122,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I do want to note -- because they also just have somewhat different incentives.","speaker":"EZRA KLEIN","timecode":{"start":4433.122,"end":4436.58,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I mean, I was noting earlier, and I think it's very real.","speaker":"EZRA KLEIN","timecode":{"start":4436.58,"end":4439.16,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"The government, particularly when it gives out grants, needs to worry about the reputational cost of the grant.","speaker":"EZRA KLEIN","timecode":{"start":4439.16,"end":4444.11,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"If the grant goes wrong, if not enough of the grants pay out into useful research.","speaker":"EZRA KLEIN","timecode":{"start":4444.11,"end":4448.61,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"If Rand Paul can stand up in Senate and make what you did sounds silly, these things really end up mattering.","speaker":"EZRA KLEIN","timecode":{"start":4448.61,"end":4453.59,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And so you get a process that is optimizing for a lot of different things.","speaker":"EZRA KLEIN","timecode":{"start":4453.59,"end":4457.8,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But the question of whether or not we do grants well ends up being really, really, really important in every country that does major capital science that I know of, and is just not the main question for a bunch of different reasons we ask.","speaker":"EZRA KLEIN","timecode":{"start":4457.81,"end":4471.6,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Yeah.","speaker":"PATRICK COLLISON","timecode":{"start":4471.61,"end":4473.13,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Another question we asked in our survey was how much time they spend on the grants.","speaker":"PATRICK COLLISON","timecode":{"start":4473.13,"end":4477.9,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I think to some extent, this is perhaps -- at least, of those who've spent some amount of time interacting with scientists, kind of more broadly known than perhaps the finding with respect to how they do -- or the degree to which they can choose what they work on.","speaker":"PATRICK COLLISON","timecode":{"start":4477.9,"end":4491.22,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But we found that -- or they reported to us that they spend on the order of 40 percent of their time on grant administration.","speaker":"PATRICK COLLISON","timecode":{"start":4491.22,"end":4500.91,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And even if one were to maintain that the decision-making apparatus around what scientists do is somehow efficient, I think it is a very tenuous position to also try to argue that 40 percent of the best scientist's time","speaker":"PATRICK COLLISON","timecode":{"start":4500.92,"end":4518.25,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"is optimally allocated towards grant applications, authorship and administration.","speaker":"PATRICK COLLISON","timecode":{"start":4518.25,"end":4524.16,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And we're not talking about an inconsequential 40 percent here.","speaker":"PATRICK COLLISON","timecode":{"start":4524.16,"end":4528.79,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I mean, this is 40 percent of the time of this super-elite 10,000, 100,000, whatever it is, some relatively finite number of people.","speaker":"PATRICK COLLISON","timecode":{"start":4528.8,"end":4540.66,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And we've chosen to take and to redeploy almost half of their time in service of technocratic, bureaucratic undertaking.","speaker":"PATRICK COLLISON","timecode":{"start":4540.66,"end":4549.63,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And getting back again to this point about people perhaps falsely assuming that things have been more inter-temporally consistent than they have, that percentage has increased very substantially over the last couple of decades as the overall edifice of science has grown,","speaker":"PATRICK COLLISON","timecode":{"start":4549.63,"end":4566.76,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"and as the kind of acceptance rates and the various thresholds for various grants has become more exacting.","speaker":"PATRICK COLLISON","timecode":{"start":4566.76,"end":4573.28,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"How we allocate people's time is really important.","speaker":"EZRA KLEIN","timecode":{"start":4573.29,"end":4576.1,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But also, just how we allocate talent is really important.","speaker":"EZRA KLEIN","timecode":{"start":4576.1,"end":4579.73,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And it brings me to something you said that I wanted to ask you about.","speaker":"EZRA KLEIN","timecode":{"start":4579.73,"end":4582.94,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"This was in response to a question about whether big tech companies are hogging all the talent in society.","speaker":"EZRA KLEIN","timecode":{"start":4582.94,"end":4587.74,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And you said, quote, \"I don't think that the ambitious upstarts who go into high speed rail in America, anyway, are going to have a great time or have much success in convincing their friends to follow them.","speaker":"EZRA KLEIN","timecode":{"start":4587.75,"end":4599.03,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I suspect that for various reasons, too many domains look somewhat like high speed rail.\"","speaker":"EZRA KLEIN","timecode":{"start":4599.03,"end":4603.94,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And so you go on to say that there's a view that the internet is a frontier of last resort, and that you don't think that's totally wrong.","speaker":"EZRA KLEIN","timecode":{"start":4603.94,"end":4612,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So tell me about that.","speaker":"EZRA KLEIN","timecode":{"start":4612.01,"end":4612.96,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Tell me about the idea of the internet as a frontier of last resort.","speaker":"EZRA KLEIN","timecode":{"start":4612.96,"end":4615.793,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But behind that, this idea that other frontiers where talented people might want to go and make their mark on society have closed.","speaker":"EZRA KLEIN","timecode":{"start":4615.793,"end":4624.822,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"You're familiar with and you've probably written about the Stephen Teles idea of kludgeocracy.","speaker":"PATRICK COLLISON","timecode":{"start":4624.832,"end":4630.91,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I kind of like the term \"kludgeocracy,\" because rather than making some of the inhibitions that people might encounter in pursuing something like high speed rail, rather than casting those as being deliberate, the valence is more that it's this kind of emergent, inadvertent and kind","speaker":"PATRICK COLLISON","timecode":{"start":4630.91,"end":4648.31,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"of complicated phenomena that nobody perhaps particularly wants or chose.","speaker":"PATRICK COLLISON","timecode":{"start":4648.31,"end":4654.05,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I think the case of California's high speed rail is quite striking, where --","speaker":"PATRICK COLLISON","timecode":{"start":4654.06,"end":4659.92,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"you've written about this and kind of similar projects and the New York subway expansion and so on.","speaker":"PATRICK COLLISON","timecode":{"start":4659.92,"end":4665.2,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And congestion pricing and so on.","speaker":"PATRICK COLLISON","timecode":{"start":4665.2,"end":4667.87,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But it's striking where it's not actually obviously a question of first order political will.","speaker":"PATRICK COLLISON","timecode":{"start":4667.87,"end":4673.117,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Like, we're willing to fund the high speed rail in California.","speaker":"PATRICK COLLISON","timecode":{"start":4673.117,"end":4675.7,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"We're clearly willing to invest in building the subway expansion in New York.","speaker":"PATRICK COLLISON","timecode":{"start":4675.7,"end":4680.53,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But somehow, somewhere between that first order decision and desire and our actual ability to kind of instantiate it, something really goes wrong.","speaker":"PATRICK COLLISON","timecode":{"start":4680.53,"end":4689.92,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And you contrast that with stories of --","speaker":"PATRICK COLLISON","timecode":{"start":4689.93,"end":4693.58,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"in the case of, say, California, Henry Kaiser and these various other early part of the 20th century operators in the physical realm.","speaker":"PATRICK COLLISON","timecode":{"start":4693.58,"end":4703.72,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And for a variety of reasons, but mostly prosaic state and county-level complications and things that would extend the time horizon of one's project, it has simply become meaningfully less-appealing for those people to undertake these initiatives.","speaker":"PATRICK COLLISON","timecode":{"start":4703.72,"end":4723.82,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I mean, Foster City, not too far from where we are now, that's named after the eponymous Mr. Foster.","speaker":"PATRICK COLLISON","timecode":{"start":4723.82,"end":4730.21,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"He was a developer.","speaker":"PATRICK COLLISON","timecode":{"start":4730.22,"end":4731.12,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"He decided, well, with reclaimed wetlands, I'm going to build a city.","speaker":"PATRICK COLLISON","timecode":{"start":4731.12,"end":4734.92,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"California is growing quickly.","speaker":"PATRICK COLLISON","timecode":{"start":4734.92,"end":4736.3,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"The Bay Area is a -- kind of propitious and will be a long-term successful area.","speaker":"PATRICK COLLISON","timecode":{"start":4736.3,"end":4741.14,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I think this place simply needs more housing.","speaker":"PATRICK COLLISON","timecode":{"start":4741.14,"end":4743.62,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And he, with that kind of founder energy, was able to give birth and rise to the city that now bears his name.","speaker":"PATRICK COLLISON","timecode":{"start":4743.63,"end":4750.79,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I haven't met anybody pitching me on a similar city on the shores of the Bay in the last couple of years.","speaker":"PATRICK COLLISON","timecode":{"start":4750.79,"end":4758.53,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But I would imagine that were one to adopt that ambition today and to propose that maybe the San Jose Marsh wetlands should themselves be an expansion of San Jose, I don't think one would get very far.","speaker":"PATRICK COLLISON","timecode":{"start":4758.53,"end":4771.59,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And in fact, even for much more sort of limited things, like additional runways or runway expansions at S.F.O., even they have now been stymied for decades at this point.","speaker":"PATRICK COLLISON","timecode":{"start":4771.6,"end":4781.63,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"That ability to translate that into something enunciated has dissipated and deteriorated.","speaker":"PATRICK COLLISON","timecode":{"start":4781.63,"end":4787.45,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And then I think the kind of individual version is, and if I want to be that heroic solar farm entrepreneur or railway magnate, that my practical ability to do so has been meaningfully curtailed.","speaker":"PATRICK COLLISON","timecode":{"start":4787.45,"end":4802.582,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Yeah.","speaker":"EZRA KLEIN","timecode":{"start":4802.582,"end":4803.29,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I mean, that's what I'm getting at here a little bit, which is talent really matters for a society.","speaker":"EZRA KLEIN","timecode":{"start":4803.29,"end":4807.94,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Where the most talented people go really matters for society.","speaker":"EZRA KLEIN","timecode":{"start":4807.94,"end":4810.82,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And a lot of those people want to go somewhere where they can have a really big effect.","speaker":"EZRA KLEIN","timecode":{"start":4810.82,"end":4814.445,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I think there's been a huge rush to digital land because you can build on digital land.","speaker":"EZRA KLEIN","timecode":{"start":4814.445,"end":4819.43,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"You can build quickly.","speaker":"EZRA KLEIN","timecode":{"start":4819.43,"end":4820.78,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I mean, it's interesting to some of the dynamics we're talking about, the temporal dynamics we're talking about, that you see this dynamic even within the tech world.","speaker":"EZRA KLEIN","timecode":{"start":4820.78,"end":4828.79,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"There was a while where it was really exciting to go join Facebook, go join Google, go join one of the big companies.","speaker":"EZRA KLEIN","timecode":{"start":4828.8,"end":4835.66,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Because you could do so much.","speaker":"EZRA KLEIN","timecode":{"start":4835.66,"end":4837.035,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And that's still, to some degree, true.","speaker":"EZRA KLEIN","timecode":{"start":4837.035,"end":4838.66,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But they got really big.","speaker":"EZRA KLEIN","timecode":{"start":4838.66,"end":4839.66,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And so crypto got -- whatever you think of crypto, one thing that is exciting about it to people is the idea that it's open land.","speaker":"EZRA KLEIN","timecode":{"start":4839.66,"end":4847.08,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"That you can go in there and have a really big effect on it.","speaker":"EZRA KLEIN","timecode":{"start":4847.08,"end":4849.58,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Build something new just with a couple of friends that might change the whole direction of the field.","speaker":"EZRA KLEIN","timecode":{"start":4849.58,"end":4855.34,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And on some level, it's always going to be harder for, say, putting high speed rail through the middle of California.","speaker":"EZRA KLEIN","timecode":{"start":4855.35,"end":4861.85,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Right?","speaker":"EZRA KLEIN","timecode":{"start":4861.85,"end":4862.42,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I mean, just building things in the world is just going to be tougher.","speaker":"EZRA KLEIN","timecode":{"start":4862.42,"end":4865.48,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But on the other hand, if you make building things in the world too hard, if you make grants too difficult -- if you --","speaker":"EZRA KLEIN","timecode":{"start":4865.49,"end":4871.15,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I know a lot of doctors who their advice to young people is don't become a doctor.","speaker":"EZRA KLEIN","timecode":{"start":4871.15,"end":4875.668,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And it always breaks my heart a little bit.","speaker":"EZRA KLEIN","timecode":{"start":4875.668,"end":4877.46,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"We need really great people to be doctors.","speaker":"EZRA KLEIN","timecode":{"start":4877.46,"end":4879.25,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And their point is not, don't go heal sick people.","speaker":"EZRA KLEIN","timecode":{"start":4879.26,"end":4881.65,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Their point is, being a doctor is too hard now.","speaker":"EZRA KLEIN","timecode":{"start":4881.65,"end":4884.17,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"The amount of time you spend dealing with insurance agencies and malpractice insurance and boards, and this and that, it's just too much administration.","speaker":"EZRA KLEIN","timecode":{"start":4884.17,"end":4894.88,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"When industries become very complicated to operate in, you want to select for people who are good at operating complicated industries, which may be different than the people who are good at moving really fast and changing things dramatically.","speaker":"EZRA KLEIN","timecode":{"start":4894.89,"end":4906.19,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But two, you kind of subtly bias where different kinds of people in your society go.","speaker":"EZRA KLEIN","timecode":{"start":4906.19,"end":4910.467,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I think in China, if you want to change a lot, you still probably go into infrastructure construction, among other things.","speaker":"EZRA KLEIN","timecode":{"start":4910.467,"end":4915.55,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Right?","speaker":"EZRA KLEIN","timecode":{"start":4915.55,"end":4916.09,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"The idea that you might be a genius rail mind, in China, that's great.","speaker":"EZRA KLEIN","timecode":{"start":4916.1,"end":4920.047,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"There's probably a lot of rail you can make.","speaker":"EZRA KLEIN","timecode":{"start":4920.047,"end":4921.88,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"That's not true here.","speaker":"EZRA KLEIN","timecode":{"start":4921.88,"end":4922.78,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And the point is not to make too much of the rail example, but to make a lot of the idea that talent flows towards where it can have an effect and people can live the kinds of heroic lives they want to lead.","speaker":"EZRA KLEIN","timecode":{"start":4922.78,"end":4934.31,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And if we have subtly pushed a lot of people into maybe not the right -- not the socially optimal directions, that over time will have a pretty big effect on a society.","speaker":"EZRA KLEIN","timecode":{"start":4934.31,"end":4944.51,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I think a constant is that some number of ambitious young people will want to do something, as you say, heroic.","speaker":"PATRICK COLLISON","timecode":{"start":4944.52,"end":4951.41,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And yeah, I think maybe two things have changed.","speaker":"PATRICK COLLISON","timecode":{"start":4951.41,"end":4954.83,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"For one, for whatever reason, our predisposition to putting those people in positions of authority has diminished.","speaker":"PATRICK COLLISON","timecode":{"start":4954.83,"end":4961.83,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And then secondly, even if placed, their ability to actually execute, again for various reasons, has been attenuated.","speaker":"PATRICK COLLISON","timecode":{"start":4961.83,"end":4968.36,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I've been reading about the university founders and presidents and those associated with some of the great US research institutions.","speaker":"PATRICK COLLISON","timecode":{"start":4968.37,"end":4977.51,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And one thing that is striking is how many of them were so young when placed in those positions of authority.","speaker":"PATRICK COLLISON","timecode":{"start":4977.51,"end":4984.26,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"You know, Daniel Coit Gilman at Johns Hopkins, or William Rainey Harper at the University of Chicago.","speaker":"PATRICK COLLISON","timecode":{"start":4984.26,"end":4990.29,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I think he was 32 when he was appointed president of the University of Chicago.","speaker":"PATRICK COLLISON","timecode":{"start":4990.29,"end":4994.61,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Even in the recent past.","speaker":"PATRICK COLLISON","timecode":{"start":4994.61,"end":4996.27,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So my dad was in the first year of the University of Limerick in Ireland.","speaker":"PATRICK COLLISON","timecode":{"start":4996.28,"end":5001.72,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Or at the time, it was called N.I.H.E. It kind of acquired university status later in its life.","speaker":"PATRICK COLLISON","timecode":{"start":5001.72,"end":5008.02,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And the Irish guy who founded it and was really the dynamo behind it, I think he was 29 when he was put in charge of that project.","speaker":"PATRICK COLLISON","timecode":{"start":5008.02,"end":5017.9,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I think it was in 1970 or '71 that he was charged with this mission.","speaker":"PATRICK COLLISON","timecode":{"start":5017.91,"end":5022.78,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But as recently as 1970 in Ireland, we were willing to put a 29-year-old --","speaker":"PATRICK COLLISON","timecode":{"start":5022.78,"end":5028.25,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I mean, that's a person meaningfully younger than me in charge of the project of overseeing the creation of a major new research institution.","speaker":"PATRICK COLLISON","timecode":{"start":5028.25,"end":5036.67,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I don't know that I have compelling or confident observations to offer in terms of the etiology underlying these changes.","speaker":"PATRICK COLLISON","timecode":{"start":5036.67,"end":5047.42,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But I think the changes themselves are important, or at least we should assume they're important if we come from a place of humility, where this is what has worked in the past.","speaker":"PATRICK COLLISON","timecode":{"start":5047.42,"end":5057.67,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Enabling these ambitious young people who are willing to contemplate spending multiple decades in pursuit of some ambitious and idiosyncratic vision.","speaker":"PATRICK COLLISON","timecode":{"start":5057.67,"end":5070,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And maybe we're more enlightened now.","speaker":"PATRICK COLLISON","timecode":{"start":5070.01,"end":5072.28,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Maybe we figured out how to get all the same innovation and all the same breakthroughs without unleashing that force.","speaker":"PATRICK COLLISON","timecode":{"start":5072.28,"end":5078.74,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But I guess my starting point, at least, would be, well, we should --","speaker":"PATRICK COLLISON","timecode":{"start":5078.74,"end":5082.3,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"before getting super confident in that or before really being deliberate about it, I think we should give some kind of credit and credence to the prescription and the methodology that's worked heretofore.","speaker":"PATRICK COLLISON","timecode":{"start":5082.3,"end":5093.97,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And before books, let me end on this.","speaker":"EZRA KLEIN","timecode":{"start":5093.98,"end":5096.11,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"We've talked a lot about scientific slowdown, about technological slowdown.","speaker":"EZRA KLEIN","timecode":{"start":5096.11,"end":5100.57,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But let's say in the next 15-year time frame, what are the three technological or scientific possibilities you're most excited by?","speaker":"EZRA KLEIN","timecode":{"start":5100.57,"end":5108.82,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"If in 20 --","speaker":"EZRA KLEIN","timecode":{"start":5108.82,"end":5109.885,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I guess it'd be 2037, we're having a conversation about how dumb this conversation was because it was right on the cusp of so much incredible stuff happening, what do you think is likely to be on that list?","speaker":"EZRA KLEIN","timecode":{"start":5109.885,"end":5120.44,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I don't know that I've super non-consensus answers.","speaker":"PATRICK COLLISON","timecode":{"start":5124.9,"end":5131.25,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I think that there are fundamental a priori reasons to believe that the rate of progress in biology could increase substantially over the years, and to your question, kind of decades to come.","speaker":"PATRICK COLLISON","timecode":{"start":5131.25,"end":5146.26,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So if in 2037 we are enormously impressed and struck by the discontinuity there, that would not shock me.","speaker":"PATRICK COLLISON","timecode":{"start":5146.26,"end":5153.48,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Clearly, over the past couple of years, there's been acceleration in progress in A.I. And kind of far for me to try to point estimate for kind of where that is in 2037.","speaker":"PATRICK COLLISON","timecode":{"start":5153.49,"end":5166.89,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But I would be surprised if that is not somewhere on that list.","speaker":"PATRICK COLLISON","timecode":{"start":5166.89,"end":5170.89,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And then I think there's something about education in the broadest sense that feels to me like a very significant, and hopefully very positive change happening in the world right now.","speaker":"PATRICK COLLISON","timecode":{"start":5170.9,"end":5184.86,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Maybe best embodied by YouTube.","speaker":"PATRICK COLLISON","timecode":{"start":5184.86,"end":5187.35,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But also by Twitter and by blogs and Substacks and even Zoom and kind of the growing ease of being in some kind of cultural proximity to people one aspires to emulating, or following in the footsteps of, or otherwise kind of being more like.","speaker":"PATRICK COLLISON","timecode":{"start":5187.35,"end":5211.38,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And to the extent that one believes my story about the significance of sociology, and culture, and mentorship, and the kind of delicate transmission of tacit knowledge, it has until very recently only been possible for that to happen to a meaningful extent through physical co-location.","speaker":"PATRICK COLLISON","timecode":{"start":5211.39,"end":5230.22,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And the fact that we've now thrown open those doors to such an extent feels to me like a really compelling and plausibly transformative change.","speaker":"PATRICK COLLISON","timecode":{"start":5230.22,"end":5241.47,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And if it were the case in 2037 that we have multiplied by 20 the number of people who can -- who have the initial mental models and understanding to become successful entrepreneurs, or successful scientists, or successful writers, or successful in whatever one might choose one's domain to be,","speaker":"PATRICK COLLISON","timecode":{"start":5241.47,"end":5264.98,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"again, I think that would not be shocking.","speaker":"PATRICK COLLISON","timecode":{"start":5264.98,"end":5266.73,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I think it's a pretty hopeful fact about the world.","speaker":"PATRICK COLLISON","timecode":{"start":5266.73,"end":5270.582,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And then always our final question.","speaker":"EZRA KLEIN","timecode":{"start":5270.582,"end":5272.54,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"What are the three books you'd recommend to the audience?","speaker":"EZRA KLEIN","timecode":{"start":5272.54,"end":5275.283,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Well, I'm right now reading \"Revolution and Empire,\" which is a book about Edmund Burke.","speaker":"PATRICK COLLISON","timecode":{"start":5275.283,"end":5279.7,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And it is just fabulous.","speaker":"PATRICK COLLISON","timecode":{"start":5279.7,"end":5281.5,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I very highly recommend it.","speaker":"PATRICK COLLISON","timecode":{"start":5281.5,"end":5283.18,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Edmund Burke, Ireland's foremost political philosopher.","speaker":"PATRICK COLLISON","timecode":{"start":5283.19,"end":5286.39,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I'm embarrassed to say that I have known less about him than I feel like I ought to have.","speaker":"PATRICK COLLISON","timecode":{"start":5286.39,"end":5290.997,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"So I recommend that very highly.","speaker":"PATRICK COLLISON","timecode":{"start":5290.997,"end":5292.33,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And the autobiography by Warren Weaver, who I mentioned, at Rockefeller.","speaker":"PATRICK COLLISON","timecode":{"start":5292.34,"end":5298.26,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"I can't remember if it's called \"Scene of Change\" or \"Scene of the Action.\"","speaker":"PATRICK COLLISON","timecode":{"start":5298.26,"end":5303.15,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But it's Warren Weaver's autobiography.","speaker":"PATRICK COLLISON","timecode":{"start":5303.15,"end":5305.61,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"That's not a great book in the sense that you don't read it -- you don't find it to be a vivid, compelling page-turner.","speaker":"PATRICK COLLISON","timecode":{"start":5305.62,"end":5312.51,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And your mind is not blown on every page.","speaker":"PATRICK COLLISON","timecode":{"start":5312.51,"end":5315.64,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But I find myself thinking back to it quite a lot and having various parts of it sort of ricochet to my mind.","speaker":"PATRICK COLLISON","timecode":{"start":5315.64,"end":5321.9,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And then it all depends on what people are interested in and all the rest.","speaker":"PATRICK COLLISON","timecode":{"start":5321.91,"end":5325.093,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And you should read the things you like.","speaker":"PATRICK COLLISON","timecode":{"start":5325.093,"end":5326.76,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But I have on my desk at home right now \"A Widening Sphere,\" which is a history of M.I.T. And I was re-reading it recently.","speaker":"PATRICK COLLISON","timecode":{"start":5326.76,"end":5337.48,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And my --","speaker":"PATRICK COLLISON","timecode":{"start":5337.48,"end":5337.98,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Who doesn't re-read the histories of M.I.T.?","speaker":"EZRA KLEIN","timecode":{"start":5337.99,"end":5340.313,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"[LAUGHS] Well, William Barton Rogers, the founder, was the son of an Irishman, and started M.I.T. substantially with his brother.","speaker":"PATRICK COLLISON","timecode":{"start":5340.313,"end":5348.93,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I find it very inspiring, I guess back to what we were saying earlier, how motivated he was and they were by a kind of broad-based desire for societal betterment.","speaker":"PATRICK COLLISON","timecode":{"start":5348.93,"end":5365.37,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Like, M.I.T. didn't inadvertently end up being a significant contribution to American prosperity and ingenuity and welfare.","speaker":"PATRICK COLLISON","timecode":{"start":5365.37,"end":5376.47,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"He was really immersed in that milieu.","speaker":"PATRICK COLLISON","timecode":{"start":5376.47,"end":5379.56,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"He paid a lot of attention to some of the cultural dynamics we were describing in England, and the Darwins.","speaker":"PATRICK COLLISON","timecode":{"start":5379.57,"end":5385.35,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And the early writing on M.I.T., if you go and just read the first two pages of the founding manifesto, it wasn't utopian in some kind of implausibly lofty sense.","speaker":"PATRICK COLLISON","timecode":{"start":5385.35,"end":5395.82,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But it was somebody who knew they weren't founding a run of the mill nth technical college.","speaker":"PATRICK COLLISON","timecode":{"start":5395.82,"end":5406.92,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"And I feel like it's easy to get cynical always.","speaker":"PATRICK COLLISON","timecode":{"start":5406.93,"end":5411.54,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"It's easy to assume that the things that really worked out worked out through happenstance, as opposed to optimism and ambition.","speaker":"PATRICK COLLISON","timecode":{"start":5411.54,"end":5420.66,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"But yeah, I find the history of MIT to be a kind of inspiring reminder that sometimes these implausible, lofty, ambitious, long-term initiatives can work out much better than one would hope.","speaker":"PATRICK COLLISON","timecode":{"start":5420.66,"end":5433.2,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"[MUSIC PLAYING]","speaker":"PATRICK COLLISON","timecode":{"start":5433.21,"end":5435.477,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Patrick Collison, thank you very much.","speaker":"EZRA KLEIN","timecode":{"start":5435.477,"end":5437.56,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Thanks for having me.","speaker":"PATRICK COLLISON","timecode":{"start":5437.57,"end":5439.185,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"[MUSIC PLAYING]","speaker":"PATRICK COLLISON","timecode":{"start":5439.185,"end":5441.554,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"\"The Ezra Klein Show\" is produced by Annie Galvin and Rogé Karma.","speaker":"EZRA KLEIN","timecode":{"start":5448.352,"end":5451.56,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Fact-checking by Michelle Harris, Mary Marge Locker and Kate Sinclair.","speaker":"EZRA KLEIN","timecode":{"start":5451.56,"end":5455.29,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Original music by Isaac Jones.","speaker":"EZRA KLEIN","timecode":{"start":5455.29,"end":5456.66,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Mixing by Sonia Herrero, Isaac Jones and Carole Sabouraud.","speaker":"EZRA KLEIN","timecode":{"start":5456.67,"end":5459.78,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Audience strategy by Shannon Busta.","speaker":"EZRA KLEIN","timecode":{"start":5459.78,"end":5461.76,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"Special thanks to Kristin Lin and Kristina Samulewski.","speaker":"EZRA KLEIN","timecode":{"start":5461.76,"end":5464.37,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"},{"text":"[MUSIC PLAYING]","speaker":"EZRA KLEIN","timecode":{"start":5464.38,"end":5467.72,"__typename":"AudioTimecode"},"__typename":"AudioTranscriptFragment"}],"__typename":"AudioTranscript"},"fileUrl":"https:\u002F\u002Fnyt.simplecastaudio.com\u002F3026b665-46df-4d18-98e9-d1ce16bbb1df\u002Fepisodes\u002Ffcb1ea11-4d31-4acf-97e9-0170278091cb\u002Faudio\u002F128\u002Fdefault.mp3?awCollectionId=3026b665-46df-4d18-98e9-d1ce16bbb1df&awEpisodeId=fcb1ea11-4d31-4acf-97e9-0170278091cb&nocache","section":{"id":"U2VjdGlvbjpueXQ6Ly9zZWN0aW9uL2Q3YTcxMTg1LWFhNjAtNTYzNS1iY2UwLTVmYWI3NmM3YzI5Nw==","name":"opinion","__typename":"Section"},"__typename":"Audio"}},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":2,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"EZRA KLEIN: Im Ezra Klein. This is “The Ezra Klein Show.”","formats":[]}]},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"This is a great conversation today. But its a tricky one to introduce, because the guest I have — Im not having him on for the thing hes best known for. So Patrick Collison — by day, co-founder and C.E.O. of the multibillion-dollar payments company, Stripe; by night, by weekend, I think, one of the most important thinkers now in Silicon Valley — certainly, one of the most quietly influential, someone who is forging and traversing an intellectual path that a lot of other people are now following.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":true,"index":3,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And its this second incarnation and role that Im really interviewing him in today — the soft power side, I guess, of Patrick Collison. Collisons work here centers around this question of progress. The argument is that human progress is much more precious and rare and fragile than we realize.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":4,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"We maybe take it for granted. We live in this time when things have been changing, atop decades and decades, even centuries and centuries, even millennia now, when things have kept changing. But for most of human history, that was not true. It was not true.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":5,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"There just was no market rapid advance in human living standards. Its only in the past 10,000 years, and then practically in the past few hundred — just an eye-blink in the time human beings have been on Earth — that things kept changing, usually for the better. And the question is, why?","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":6,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And Collisons particular meta question is, given the clear fragility of forward motion here, given how rare it has proven to be — and so how easy it might be to lose — why isnt the question of the conditions of progress more central? Why isnt the study of progress in a wide multidisciplinary way a more common and central discipline?","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":7,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"Collison has written a few influential essays here, with the economist Tyler Cowen. He called for the inauguration of a discipline — they call it progress studies — and that now has people studying it. Theres people creating journals for it, creating syllabi and podcasts and books around the topic. Its one of the more singularly successful calls for a research direction I have seen.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":true,"index":8,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"Separately, in a piece co-authored with the scientist, Michael Nielsen, Collison and Nielsen argued that, though it is hard to measure, it seems like the rate of scientific progress is slowing down, and thats particularly true if you account for how much more were putting into science, in terms of money, of people, of time and technology.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":9,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"Now, these ideas are not original to Collison. The point is not that nobody studied human progress before this or worried about the pace of scientific research. He wouldnt claim that. It wouldnt be true. But he is playing a distinctive role in their framing and their popularization, and in creating and funding a community around them.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":10,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And what I see in my travels here is that it is working. Something is burbling here. But I cant find many big pieces where Collison really lays out his worldview. There are a couple essays, tweets, interviews, but hes not been primarily writing this down.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":11,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"What he has been doing is funding it through Fast Grants, which has been successful, but more than that, intellectually influential effort to show you can give out scientific grants quickly and with very little overhead, through the Arc Institute, a big biotech organization hes creating to push a researcher-first approach to biotech, and through giving a bit of money, and a bit of time, and a bit of prestige, and a bit of networking to a lot of different projects that circle these questions.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":12,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"Hes got this funny quality of being nowhere in particular, but also somehow, almost everywhere, if youre interested in these questions. So what I wanted to do in this conversation was try to get as close as I could to the Patrick Collison worldview, the underlying theory of the case here that animates his thinking his funding, and the ways in which hes trying to nudge the culture hes a part of, or the ways in which hes trying to actively create a culture he doesnt yet see.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":13,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"As always, my email — ezrakleinshow@nytimes.com.","formats":[]}]},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"Patrick Collison, welcome to the show.","formats":[]}]},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"PATRICK COLLISON: Great to be back.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":14,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"EZRA KLEIN: So youve made the argument that science — all science — is slowing down, that were putting more money and more people into research, and were getting less and less out of it. Tell me about that.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":true,"index":15,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"PATRICK COLLISON: Well, I want to separate two things. Theres a question as to whether science in its totality is slowing down, in terms of the absolute returns from it. I think that might be true. You can maybe divide up the first half of the 20th century and the second half and so on, and sort of try to compare one with the other.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":16,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And we had general relativity and quantum mechanics and various other major breakthroughs in the first half. You can ask the question of, well, did we have as many in the second half? But in the second half, we did have the discovery of D.N.A. and molecular biology and lots of other things.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":17,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"So I dont know that I would claim a total slowdown. The thing that I think is clearer and should be very concerning to us is, as you look at the number of scientists engaged in the pursuit of science, and if you look at the total amount that were spending, and as you look at the total output, as coarsely measured by things like papers and number of journals, all of those metrics have grown by, depending on the number, lets say, between 20 and 100x between 1950 and, say, 2010.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":18,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And if you look at it on a per-capita basis, or a per-unit-of-work basis, now used to divide all those total outcomes by a factor of 50, and it seems like if you imagine yourself as the median scientist, youre meaningfully less likely to produce anything like as consequential a breakthrough as you would have, say, in 1920. And so Michael Nielsen and I, in order to try to put slightly more rigor on that question — we went and we surveyed a bunch of scientists across a number of universities in a number of different disciplines, and we presented them with different Nobel Prize-winning breakthroughs.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":19,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And we tried to compute an approximate ordering of their significance in the eyes of these scientists. And the thing that would kind of have to be true — for the per-capita impact, we remain in constant — is wed have to be discovering much more important things in the latter half of the 20th century in order to compensate for, to make it worthwhile, for us to be investing this 50-fold greater effort.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":20,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And we didnt find that. In physics, in the estimation of physicists, there was a kind of flat-to-declining trend. Its not super obvious which way it points, but in as much as theres a trend visible, its probably slightly downwards. And in other fields, it was maybe similarly equivocal, perhaps a slight increase, visible in some, but importantly, in no fields that it looked like were on this crazy, exponentially improving trajectory, which is what you would have to have for this per-capita phenomenon to not be present.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":21,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And I think that should be something were interested in for multiple reasons. One, because presumably, as a society, were interested in just how much more scientific progress and technological progress and so forth, how much more innovation is there going to be over the next 10 years or the next 50 years or the next century. But also, because theres kind of two possibilities. One possibility is, fundamentally, were running out of low-hanging fruit, and its just going to be harder to do this stuff.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":true,"index":22,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And in as much as were setting investment or making investment decisions around to what degree should be pursuing the stuff, I guess its important to know what we think the returns should be. Or the other possibility is, somehow, were doing it suboptimally. Something changed, and we were pursuing this process of discovery more effectively in the past, and presumably, for inadvertent reasons, something went wrong, and now, were just less efficient at it.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":23,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"But either explanation — and it doesnt necessarily have to be fully binary — but either explanation is important, and either explanation, I think, has prescriptions for what we should do going forward.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":24,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"EZRA KLEIN: Let me start with the low-hanging-fruit explanation, which I think is a more popular one. And you have — in the piece you did on this with Michael Nielsen, the sad, but in the very academic way, very funny quote from the physicist Paul Dirac, who says of the 1920s, there was a time when, quote, “Even second-rate physicists could make first-rate discoveries,” which I just kind of love.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":25,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"But the theory there is you can only make a lot of the big discoveries once. You discover quantum mechanics once. You discover the atom once. And most of them have just been made, so what you have now is more complicated, smaller, requires much larger teams of people, much more complicated experiments, with much more infrastructure.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":26,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"So were just structurally in a period where its going to get harder and harder and harder to make big gains. Do you believe that?","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":27,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"PATRICK COLLISON: I think its possible, but even though its intuitively compelling on some level, Im not sure that its true. Its probably true to at least some degree for some particular research direction, right? We go after discovering the various subatomic particles, and initially, without too much difficulty, we discover the electron or whatever.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":28,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And by the time weve discovered the nth quark, its now gotten super hard, and even with ever-larger particle accelerators, were not necessarily making breakthroughs of the same magnitude. So I think its pretty true for a given direction. But obviously, the question is, well, to what degree is progress in any area opening up other directions, right?","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":true,"index":29,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And so I mean, you mentioned the Dirac quote and, say, physics in the early part of the 20th century. Those discoveries opened up new techniques and investigation methodologies and so on, that then gave rise to molecular biology in the 50s, 60s and 70s. And so theres kind of a combinatorial benefit, where discoveries over here or discoveries over there might unlock opportunities and major breakthroughs in areas that we could not have foreseen in advance.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":30,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"There are lots of, quote unquote, “low-hanging-fruit discoveries” made in computers and computer science in the 70s, 80s, and 90s. Maybe were even still in that regime, right? Were still making some pretty fundamental breakthroughs. And of course, again, those, quote, “low-hanging discoveries” would not have been possible without a lot of this optimization and discovery in other fields.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":31,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And so I think its probably true for a given research direction, but the relevant question for society is, is it true in aggregate. And there, its much less clear to me that it is.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":32,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"EZRA KLEIN: I want to read something provocative you said in an interview with the economist Noah Smith. And you said, quote, “Most systems get worse in at least certain ways as they scale. The idea that science could have gotten worse in significant ways sometimes sounds strange to people. Like, were doing so much more. How could that be bad? But I think that misses the many examples of sensitivity of scientific processes to institutions and culture. Swiss nationals have won more than 10 times more science Nobels per capita than Italians have. 10 times. And yet, theyre neighbors. And Italy certainly isnt lacking in scientific tradition — Fermi, Galileo, the oldest university in Europe, et cetera. The how of science just really matters.”","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":33,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And this seems, to me, to be where your exploration really goes. So tell me what you think might have gone wrong in the “how” of science.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":34,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"PATRICK COLLISON: So I think this point about the sensitivity of scientific outcomes to the specifics of the institutions and the cultures is very important and probably underappreciated. At the beginning of the 20th century, not only was the U.S. not a scientific powerhouse, but it barely had a presence in frontier research, whatsoever.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":35,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"To become a credible researcher in the U.S. in 1900, you almost certainly had to go and spend time in, most likely, Germany, and failing that, in France or England — you know, what have you. And by 1900, the U.S. was already a pretty prosperous place, and it had a well-educated society, as societies went.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":true,"index":36,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And yet, somehow — and it had universities, right? I mean, Harvard was hundreds of years old by that time. And so it checked many of the ostensible boxes, and yet, the sum total of the U.S. research output as of 1900 was still de minimis.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":37,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"When James Conant, who was later president of Harvard for 20 years — when he went to Germany as a chemist, which was his original training, in the 1920s, he recounts how dispirited he was by what he found there and how far ahead of Harvard German research was, as of the early 20th century. And then, for a variety of reasons, all sorts of cultural, institutional funding — various transformations happened. And of course, by the latter half of the 20th century, the U.S. was the unquestioned leader at the frontier of scientific progress.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":38,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"If you look backwards, you see where that locus has been, where the most successful and fertile scientific grounds have been — it has repeatedly moved. As we just said, maybe the 19th century, it was Germany.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":39,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"Before that, in the 18th century, it was plausibly France. They had a couple of these really successful École Polytechnique and Grande École and so on. And so as a kind of first-order empirical matter, we can just notice, huh, this really seems to matter — and then, the example you just gave of the divergence between Switzerland and Italy.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":40,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And so then, if we kind of accept that, and we try to ask ourselves, well, specifically, what are the mechanisms? You know, whats actually going on? Its hard for me to say. It seems like the transmission of research culture by individual researchers matters a great deal.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":41,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And you see these kinds of pockets of the cultural transmission repeatedly crop up, where Gerty and Carl Cori — you probably havent heard of — they ran a little biology lab in Missouri, and no fewer than six of their trainees, of students they trained, went on themselves again to win Nobel Prizes.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":42,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And if we tell ourselves a standard kind of mechanistic story as to, well, its the funding level, its how much are we investing in science, or its something about whether theres an institution in the courser sense, that can possibly be amenable to it, its very hard to explain these eddies where you see these pockets of excellence really produce these outsized returns. So I think its a complicated question.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":true,"index":43,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"I think all of aggregate culture, funding, institutional characteristics, and so on all contribute to it. But if I had to isolate a single variable, it seems to me that the research culture set by specific people and the tacit knowledge transmitted through direct experience is probably the number-one thing.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":44,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"EZRA KLEIN: This, I think, is where I sometimes fall into my own pessimism on this. Because I want to believe, as you do, that we can double the rate of scientific advance, maybe even go further than that. But I think the prediction — if Im putting this on institutions, on culture, on pockets of transmission and mentorship — I think the prediction I would make is then, even if you believe, say, that America had a great 20th century, but its institutions have become sclerotic, and weve slowed down, and everything is piled in lawsuits and review boards now, somewhere else that didnt have that, that has a different culture, that has different institutions, would be pulling way ahead.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":45,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"So you might think, well, China will be pulling way ahead. And youve noted this in some places. Were getting a lot of peer-reviewed research out of China — huge number of citations out of China. Were not seeing them dominate the big breakthrough advances of the era.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":46,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"It doesnt seem like Europe is lapping us. And so if you think this slowdown is somewhat global, then that seems to me to militate against questions of individual institutions, cultures, how different labs work, because there is so much variation that you should have some of these labs that are doing it right, some of these places that havent piled on a little bit too much bureaucracy. But I dont think we really see that.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":47,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"PATRICK COLLISON: This diagnosis of these phenomena to cultural, institutional, mentorship-related, interpersonal dynamics, and your observation that its not obviously the case, that there are other places we can pointed that are doing it so much better — for me, my takeaway is that, well, successful cultures are a pretty narrow path. Homo sapiens emerged 200,000 years ago.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":48,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And as far as we can tell, for the first 190,000 years of our genesis, we think we were largely biologically equivalent to the people we are today. But as best we can tell, there was some kind of cultural capital that those people lacked for a very extended period of time before human societies in somewhat recognizable modern form started to emerge — agriculture, all the rest.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":49,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And in a similar vein, we had many billions of lives and centuries elapsed before the Industrial Revolution., and before we started to put together many of the input ingredients or enough of the input ingredients that we can get sustained improvement in standards of living and ongoing economic growth and progress. And so your point about, well, as I look around, I dont see anything or anywhere thats obviously better, I agree with that.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":true,"index":50,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"But again, my takeaway is that thats what makes the question of how do we improve or how can we do somewhat better so urgent and pressing, where its many things have to go right. Its not easy to be even as good as — or to get to a place where things are as good as they are today. What we have is very precious. And I think the threads and the themes that youve been pulling on of late — all of these dynamics underscore their importance.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":51,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"EZRA KLEIN: I think thats a good bridge to progress studies as an idea. And I want to have people hold in their heads that idea that progress is very narrow, that it is a very narrow bridge that we have walked on for a very short period of time. But lets try to define it.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":52,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"When you say progress here, what are you actually talking about? Is it just shorthand for economic growth or G.D.P.? What is progress?","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":53,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"PATRICK COLLISON: Well, I dont know that I would claim to put forth some kind of definitive definition. And I think, to some extent, our intuitions around it are probably broadly correct. And so it might not matter to define it super precisely and finely.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":54,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"For, me it is something along the lines of our success in realizing a liberal, pluralistic and prosperous society, and a sense among people that their offspring can and probably will do better than they themselves have, and that more broadly, the future will be better than the past, and that were at least making incremental progress towards embodying values and morals that we collectively think we can be proud of.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":55,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"But I dont think anything that novel in that. I dont think my conception of progress would differ that materially from some kind of average aggregate over any other group of people in the country.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":56,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"EZRA KLEIN: I do think theres something interesting, though, which is that if you look at eras that I think progress-studies-type people and economic-growth people and historians of economic growth study most closely, actually, some of the periods where people feel a lot of rapid progress dont fit that at all. You have, say, the Industrial Revolution, where life spans and lifestyle get worse for a lot of the people.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":true,"index":57,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"I dont think one will look at that period as unbelievably pluralistic. You have a lot of periods of war when you have very, very, very rapid technological progress, but it happens in context of much more martial societies. So there is an interesting tension, at least in periods — and some of them quite long, actually — where you can have fairly rapid economic progress, but it comes at a cost that I think isnt always acknowledged, but is an important thing to think about.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":58,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"PATRICK COLLISON: Yeah. So I dont think you could point to some of these periods in the past and say that they definitively embody to the extent that we would fully aspire to some of these broader traits and characteristics. But I think the question is more, what are they doing as — you have to judge it relative to the baseline that preceded them.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":59,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And I dont know that the 18th century in the U.K. is some ideal as a society. But if you compare it to the 16th century in the U.K., the ideals and ideas of natural rights and religious tolerance and so on — they were somewhat better embodied by the 18th century than they had just a couple of centuries previously.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":60,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And similarly, in the U.S., say, during either war or the 30s or whatever, again, its not like that was any kind of perfect society, but assessed relative to the society of 1830, I think it compares relatively favorably. And I think its not a coincidence that Adam Smith — his first book, of course, was on ethics and morals and trying to instill better general ideals and behaviors across a society.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":61,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And maybe after that, he then argued for and laid many of the foundations of what we would recognize as modern economics. So I dont think its perfect. But on average, I think the correlation is positive.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":62,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"EZRA KLEIN: So lets talk about the Industrial Revolution for a little bit here. I think a lot of people locate a takeoff in human living standards — it continues to this day — there. And its strange in a way, right? “There” is a very geographically contiguous spot. Its the U.K. — England, actually, I should say, at that point.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":63,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And there is a moment in time that probably could have come at another moment in time, depending on how human history plays out in the counterfactual. I know that you have an interest in the theories of why then, why there. How do you work your way through them? What do you think is persuasive for why then, why there?","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":true,"index":64,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"PATRICK COLLISON: Well, you know, again, I caveat. With all of these topics were discussing through this podcast, maybe the first-order banner for all of them should be, I dont know, these are my best guesses, and I think its important that all of us were pretty humble in the claims and the assertions and the beliefs that we hold.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":65,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"Recently, Ive been reading a bunch of Irish and Scottish writers around then. Its very interesting, because for both the Irish and the Scots, there was a sort of a pressing and kind of obvious question where England was much more prosperous than they were or we were. And theres no super obvious explanation for that. There wasnt an obvious climatic or natural resource endowment that England benefited from that was lacking in Ireland or Scotland.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":66,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"It wasnt like England was actually a vastly larger polity. The orders of magnitude were comparable. And Bishop Berkeley wrote this book, “The Querist.” He was asking these questions directly, just like, whats going on? Whats wrong with Ireland? You know, why cant we do this?","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":67,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And then, you have the Act of Union in 1707, uniting Scotland and England — and sort of similarly, of all these Scottish thinkers being like, all right, were now literally the same country. Why are we so much more impoverished? And then, if you shift to England, theres Joel Mokyr and — youve read his work — and more recently, people like Anton Howes.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":68,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And in a similar vein, they go back to — I mean, the word, improvement, came from Francis Bacon, or it was kind of popularized as a concept by Francis Bacon. But thats noteworthy, right? Like, that was not a pervasive broad concept in the 15th century.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":69,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"I mean, literally, the word, improvement, in this broader societal context, came from word, “translated,” at the beginning of the 17th century. And the ultimate conclusion that these historians and scholars and analysts of the Industrial Revolution come to — and I think its a correct one — is somehow, whether its through Bacon or Newton or various of the tinkerers who produced some of the earliest technological breakthroughs, that somehow, this improving mind-set became pervasive.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":70,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"You had societies explicitly — like the Hartlib Circle or the Lunar Society, or the Select Society, and the club, and so on — all these societies explicitly devoted to figuring out ways to advance the state of affairs that prevailed. And these societies were comprised of many of the leading people and thinkers and so on of the day.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":true,"index":71,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And it seems maybe a bit satisfyingly squishy to attribute it to something so hard to pin down. But as you run through all the possible other explanations, its differences in IP law. Its difference in the Malthusian conditions. Its difference in the prevalence of coal, you know, et cetera, et cetera. Through various cross-sectional analyses, you can exclude most of these in looking at all of Ireland, Scotland, and England.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":72,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"It really does seem to me that differences in the mind-set and in the culture are where you have to net out. And thats not to say maybe that its fully sufficient. There might be other preconditions that are important. And then, maybe as a last thing to say, it is striking to me that many of these kind of original 18th-century economic writers and thinkers — and again, the kind of people we look to as the founders of much of the discipline — that they themselves were kind of centrally preoccupied with this.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":73,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And yeah, they were in favor of free trade and specialization and human labor and lots of these concepts that were now very familiar with, but they really thought that general mind-set played a big role, too.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":74,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"EZRA KLEIN: So lets talk about Joel Mokyr ideas for a minute. So Mokyr is an economic historian. People should read his book, “The Culture of Growth,” which is really fascinating. He argues, as youre saying, that in this period, this mind-set that we can increase the store of usable knowledge, and then use it to alter nature, to better the human condition, takes hold.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":75,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"Thats a new mind-set. Its different than religious ideas of the past. Its different than cultural ideas of the present. And that, plus a bunch of other things, particularly the republic of letters, the way people are writing letters back and forth, kind of combine into a culture that is able to grow.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":76,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"But one of the things that I really take from his work, that sits in my head, is he believes its all very contingent. He really believes it might have not happened. But the other is that I think it opens up this question that as a tech person, Im curious to hear your thoughts on, which is, he really believes — Mokyr really believes — that there is a communications infrastructure that arises at that time, that has a kind of culture of generosity and argument and honesty in it, and is built on writing letters slowly to one another, and then copying those letters over to other people.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":77,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And that culture is really good for intellectual advancement. I think one of the promises of the internet and the age we live in is, its all faster. We can write to people immediately. Things we write can go viral and be seen by 5 million people all of a sudden.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":true,"index":78,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And that was going to speed up economic growth really, really rapidly. And I would say, you dont see that. So Im curious how you think about communication cultures here and what you think for all the advantages of ours we might not have.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":79,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"PATRICK COLLISON: I mean, I think its hard to say in aggregate. I feel its pretty likely that the effects are very heterogeneous across different populations. And youve made the case that you think Twitter is bad for journalism and for journalists.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":80,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And I guess you live this yourself with your now mostly inactive Twitter account, I guess, apart from announcements. And I think in the case of the internet, that its almost certainly a tremendously large gain that billions of people now have access to educational materials. And some of the otherwise hard-to-communicate tacit knowledge — that things like YouTube videos now made legible and available.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":81,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And I think its true that there are various gravity equations that we see across different disciplines. I mean, in economies themselves, in trade, where you rapidly decline in propensities to trade as countries get further from each other — but you have versions of this in academic disciplines as well, where geographic distance correlates inversely with likelihood of the exchange of ideas and so on.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":82,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And I think its clearly the case that the sort of reaction surface area has increased substantially by the internet there and represents a kind of efficiency gain for people looking to exchange in ideas. Many of the companies that Stripe works with are remote companies, and they might employ people across myriad countries, and thats a kind of communication and efficiency gain that would certainly not otherwise be achievable.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":83,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"I think its worth recognizing that the aggregate amount of G.D.P. that we are creating or gaining every year is so much larger now than — I mean, the percentage might be the same. But the total amount of stuff happening, or the increasing amount of stuff happening, is so much larger now than it was 100 or 200 or 300 years ago.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":84,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And so for all of those reasons, I think we should give superior communication technologies and faster communication technologies a significant amount of credit, even though the ways in which those are manifests might be hard to measure and somewhat prosaic.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":true,"index":85,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"Take my mom, for example. My mom works with a hospital in Minnesota. Our youngest brother has a physical disability. And in the course of that, she trained herself in treatment for cerebral palsy, this condition, and she wrote a book about it, and she did a masters in this. And now, shes trying to improve treatment for this condition throughout Ireland, in the U.S. and other countries as well.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":86,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"Shes a retired Irish mother who spends some of her year living in the U.S. near her sons, spends the rest of her year living in Ireland, working at a hospital in Minnesota, who just got a proposal to have her book translated into German a couple of days ago. And thats a relatively prosaic story, but literally, millions of these stories exist in kind of aggregate form around the world.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":87,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"To circle back to the initial thrust of your question, though, I think its at least possible that the internet is bad for civic discourse. Im not saying it is, but its certainly in the realm of plausibility — and that perhaps both things are true, where theres some kind of iceberg where there are these enormous welfare gains that are not that legible, not that visible, lie beneath the surface, and then certain of the most visible manifestations, like what we see on cable news or what we see written in the papers — perhaps that is worse, and perhaps, slightly more structural judiciousness would be desirable there.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":88,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"EZRA KLEIN: I want to try to flip that and suggest that — because Im going to push some counter ideas on why we maybe dont see as much progress as we wish we did. But one is that I think possibly, very large welfare losses lie beneath the surface. And beneath the surface of stories like the one you just told about your mother, I think we all have stories of ways or people for whom the internet has unlocked a possibility.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":89,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"I mean, my whole career is built on the internet. I was an early blogger. I got rejected from my student newspaper. And if there was no blogging, like, god knows what would have happened to me. [LAUGHS] I mean, nothing too terrible, probably, but I wouldnt have the career I have today.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":90,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And at the same time, I think that the group of people who, by luck or by temperament, proved very, very good at using the internet, to some degree, distracts from the many, many, many people for whom the internet is fundamentally a distraction machine, or for whom the internet is creating, because of what we built on it. You know, shorter attention spans — how many people would have had an idea, sitting in a room by themselves, or taking a walk, that they never have now, because they never have to have a moment where theyre thinking alone?","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":91,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And so one thing that I think were all loathe to do is well talk a lot about how its weird that we have so much more knowledge, but productivity isnt increasing faster. Its weird that we have so much more rapid communication between researchers, but science isnt advancing faster. And then, the idea that maybe there are things happening to us that makes us less able to use that increasing stock of knowledge well, or makes us less able to collaborate in a useful way, I think, gets dismissed rather quickly.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":true,"index":92,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"But I dont think its totally implausible. Now, I dont want to say, like, the greatest technology we ever had was letter-writing. Obviously, the greatest technology we ever had was blogging in the early aughts when I became a blogger. And whatever happened in your 20s is, like, as good as it was ever going to get.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":93,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"But I do wonder about these questions. And I think something Mokyr is right to put a lot of attention on is communicative cultures. Communication is how we collaborate. And if communication is in any way getting worse, its going to have pretty big macro effects.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":94,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"The other thing is if you believe these cultures matter, weirdly, as big as were getting, the internet allows a certain disciplines culture to stretch boundaries and borders in time in a way that it would have been harder. I suspect that labs were more different 50 years ago than they are today.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":95,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"The countries and the disciplines of researchers and the cultures of researchers in countries or cities are more different from each other 50 years ago than today, which is great if we have the best of all cultures today, but its not that great if you actually think variation is really important.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":96,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"PATRICK COLLISON: Lets wrap up there. So first, I agree, as a basic matter, that there are welfare losses occurring across society that we should be worried about, and probably everybody listening to this is familiar with the Stephen Pinker case for optimism, and rather than focusing in the headlines, you zoom out, look at these long-term time series. And once one does that, things seem a lot more encouraging, whether you look at it by income or life expectancy or infant mortality or choose your metric.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":97,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"Something thats been striking to me of late is if you change the x-axis on those time series, and look at many of those phenomena and trends over a much shorter window, the valence changes substantially, and life expectancy in the U.S. is now, in fact, declining. According to C.D.C. data, 54 percent of teenage girls now report persistent feelings of sadness and hopelessness. And you could say, well, teenagers were never stereotyped as the most cheerful lot, but we do have some degree of longitudinal data here, and that number is up from being in the 20s as recently as 2009.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":98,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"½ the population now is either prediabetic or diabetic — again, according to the C.D.C. Basically, point is, when we look at more recent windows, I think there are plenty of aggregate, emergent, complicated outcomes and phenomena that should give us concern. On the degree to which we should attribute the diagnosis to the internet or to our kind of communication media more broadly, its less clear to me in that — not saying its not true, but presumably, the life expectancy one is not — or at least if it is, the mechanism has to be very complicated.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":true,"index":99,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"There are a bunch of other health-related ones. So take, for example, say, the incidence of diabetes or pre-diabetes. And you could say, OK, fine, all those things might be true, but theyre totally different. I guess the question I wonder about is, well, we know that lots of basic biological outcomes are correlated with mental states and so on.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":100,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And so to what degree is there some more nuanced and complicated relationship there? But I think its a fair question, and I wonder a lot about it myself.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":101,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"EZRA KLEIN: Let me ask you about how you think, over the long period here, about the relationship between technology and equity or egalitarianism. And something specific is in my mind. I flicked earlier at the way the Industrial Revolution, for an extended period of time, seems to have reduced a lot of peoples living standards. And it wasnt till later you had changes in redistribution in labor unions and labor protections that the amount of material prosperity that was generating created more broad-based prosperity, particularly at a very high level.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":102,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"I dont know that you can sustain that kind of thing today. We have much more a small-d democratic culture. If things arent working for people, its much easier for them to organize and be heard.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":103,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"I think theres a much more direct and complicated relationship now between whether or not people feel benefited by technology, and whether or not they are going to accept the conditions and the risks of rapid technological advance. But Im curious, from your vantage point, how you see that both kind of historically and currently.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":104,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"PATRICK COLLISON: I agree with that. I worry a lot about the basic stability of a society that does not successfully generate and make sufficiently broadly accessible the benefits of economic growth. The world simply has too little prosperity. And if it is not the case that people in the U.S. or people in any country — if they either feel like things arent progressing, or if they feel like maybe somewhere distant from them, things are progressing but they personally will never be able to benefit from it, I think we put ourselves in a very dangerous and likely unstable equilibrium.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":105,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And if you go back to — well, you dont have to go back very far in history to see, obviously, plenty of instances where this kind of instability brought the whole house of cards down. And so as a consequence of that, I worry a lot about, how do we simply make sure that — or one of the small things we each individually can do to try to make sure that society is generating enough economic gain and enough broadly experienced welfare gain that the whole compact can be maintained?","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":true,"index":106,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And again, I dont think theres a ready neat kind of singular answer to that. Maybe Stripe as part of our small little contribution in one little fissure. But I think the central question youre getting at is super important.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":107,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"EZRA KLEIN: And one of the questions I wonder about there — weve talked about the way progress has been very geographically lumpy, lets call it, right? Theres a lot that happens in very small places, and it ends up affecting the whole world. Obviously, then, the gains of progress sometimes have that quality, too.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":108,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And I do think of one of the politically destabilizing effects of the past, lets call it, 30 or 40 years of digital progress, is being the concentrations of wealth. We just used to have a lot more spread. Even putting the questions of rising inequality aside, just where rich people were was different.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":109,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And so where they were giving a lot of money to the local hospital was more spread out, say, across the country or in other countries across the land. But here, even as the internet is supposed to democratize distance, and in many ways, has — I mean, telework is not a fake phenomenon. It has really concentrated the wealth of that to, literally, where were sitting, but to New York. Theres a lot of money now in Austin.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":110,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And then, on top of that, you often have barriers of entry, in terms of how many homes can be bought. So its not even like people can move to the place where all the economic opportunity is happening. And I do think that creates some of the skepticism you see of technology.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":111,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"I dont think a lot of peoples — I think people are really excited about a lot of the goods theyve gotten from it. But in this kind of macro political sense, as youre saying, in a period of a lot of change, a lot of folks with real backing in the data dont feel life has gotten better at the macro level.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":112,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"Life expectancy, happiness, political stability — its not like you can look around and say, well, I got this computer in my pocket, and everything else is going great, too. Its like, I got this computer in my pocket, and what it keeps telling me is that everything is going to hell. Now, maybe its telling me that a little bit too much, but there is validity to the narrative.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":true,"index":113,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"PATRICK COLLISON: Yeah. So again, vehement in agreement on the sort of central importance of making sure that improvements in the standard of living are actually broadly realized across the society. That, too, I think, could serve as a manifesto for some of these Progress Studies ideas.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":114,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"On the internet in particular, or on technology and the technology sector and so forth, I think its complicated and difficult to try to sort of fully collapse or linearize it or something, where on the one hand, you have some of these concentration dynamics you identify. At the same time, of course, it is also a tremendous and incredible dispersal agent in making some of those possibilities and opportunities be more broadly available.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":115,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"I think its dangerous to take an excessively U.S.-centric perspective here. If you interact with or look at survey data, or otherwise try to assess whats the sentiment of people in Poland, whats the sentiment of people in India, or whats the sentiment of people in Indonesia, they view the internet extremely positively. And I think correctly so, where their opportunities for advancement would be substantially curtailed in the absence of much of what the internet makes possible.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":116,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"I think in places like the U.S., or actually, even at home in Ireland, some of this story is complicated by lots of other things, but including — and I think, substantially — dynamics around housing policy, where theres an extensive literature showing that, for example, a very substantial moderating effect on the increase in wealth inequality that would otherwise have happened, or income inequality, was geographic reallocation and people responding rationally to, OK, things in New York are going great, or things in California are going great.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":117,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And if you look at the rate of increase of the Californian population, say, through the 1960s, that was a tremendously potent mechanism for us redistributing some of the economic gains that were being realized at the time. And of course, now, we have this crazy position, where California is losing population at the same time where the market caps of these companies and the profits of these companies are increasing very rapidly.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":118,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"But as one assesses that dynamic and tries to ask the question of, well, why arent these gains being better or more broadly distributed, its certainly not clear to me that the answer even lies in the realm of technology qua technology. And I think its certainly more broadly, again, some of these considerations like geographic allocation.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":119,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"EZRA KLEIN: Let me ask one more question on the geographic dimension, and then Ill move on to it. And its on my mind, in part because when I try to think about progress, when I try to think about what inventions and innovations are coming really quickly, I actually see a bunch here. And Ill use A.I. as an example.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":true,"index":120,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"Ive met people who are trying to automate a bunch of legal contracts. It makes a ton of sense. People pay a lot all over the country — to some degree, all over the world — to get fairly basic legal contracts drawn up — wills and real estate documents and merger agreements and all kinds of — from the small to the large.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":121,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"If you imagine that getting really effectively automated, though —","formats":[]}]},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"you think about Saint Louis, Missouri, where some of the people who are important pillars of the community work in law firms there, and what they do is contracts. They do estate planning and all the things that people have to do in contracts. And if it actually does get concentrated to really, really great contracting firms in the Bay Area or in New York, on the one hand, the democratizing potential will really be realized. Those contracts will get cheaper.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":122,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"Theres also a theory in crypto of smart contracts. And on the other hand, you really will have a lot of that — the gains of that, economically, going to smaller areas and aggregated across a bunch of different domains. So graphic design, in all kinds of areas of the country — midlevel graphic designers get paid to make logos for local businesses.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":123,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"Its pretty clear theyre going to be able to do that really, really easily on things like DALL-E pretty fast. So you can imagine a lot of that area getting wiped out. And you kind of run through a couple of these. And before you get to really unbelievable and sci-fi-like dimensions of artificial intelligence, you just have a thing that is going to democratize a lot of capabilities in a way thats going to put the money for those capabilities both a little bit back into the pockets of the people who need them, and then a lot into the people who run the best A.I. rigs and is going to have a really weird geographically destabilizing effect.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":124,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And that paradox of the internet both democratizing geography, and then concentrating wealth and capital in very small areas is, to me, a central challenge. Because if you get that wrong, if it goes too much in the concentration area, I think were going to lose a lot of the political stability we need here. But youre more on top of these technological advances than I am. Do you think the trends there are going to play out differently than Im worried they will?","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":125,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"PATRICK COLLISON: First, yeah, its not — I dont think its foreordained whether or not these are going to be centralized technologies. I dont know. And on the one hand, theres, I think, an obvious feature we can contemplate, where there are only three A.I. models, and they are rooted in the hegemons, the citadels of Silicon Valley technology, and we all are digital serfs who are subsistence-farming on their gains.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":126,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"I think theres also a very plausible story where these technologies prove substantially less defensible than we might have expected, and where, instead, they have this enormously decentralizing effect. Because otherwise, economies of scale that only large firms could benefit from can now be realized and pursued, even by massively smaller firms. And if we look at the recent history of A.I. — I dont think any clear story there, but it does feel to me that it has been more biased towards the second story than the first.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":true,"index":127,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"There are now multiple companies with large language models. There are a number of very successful open-source A.I. efforts. Actually, there was a really cool example from Replit, which is a service — its a programming I.D. in the browser, used by kids learning to code, but also increasingly used by people who are pursuing serious programming.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":128,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And they recently released a GitHub copilot-like technology, where it will kind of autocomplete your code in the editor, and where you can do some pretty cool things. Like, you can highlight a block of code and ask it to be explained, and itll turn code into natural language, into English, and say, hey, heres what this code is doing.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":129,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"Anyway, they wrote a blog post about how they built this, and they describe how it was built by one guy over the course of a couple of weeks. And maybe thats only the case in the early days of this AI technology. I mean, in early computer games, the first games were built by a single heroic person, and now, its these gigantic studios and enormous CapEx budgets.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":130,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And so I think the fact that this is the case today doesnt mean that it will remain the case through time. But my takeaway is that at least not foreordained that AI or any of these other technologies will be centralizing forces. And then, the other thing to observe is that when we talk about these being centralizing, I think theres a question as to, do we look at it in relative or absolute terms?","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":131,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And my contention would be that, both from a moral standpoint, but maybe more importantly from kind of a political-economy standpoint, what will matter is whether, on an absolute basis, people feel like they are realizing opportunities, their lives are improving, that things are getting better, that their kids will be in a better situation and so forth. And exactly how much value is realized by the companies themselves doesnt actually matter that much, compared to that former question.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":132,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And whether A.W.S. or whether any of these organizations has super high or super low profit margins, I dont know is nearly as important as what is the actual effect on these communities and individuals across the society. And so in as much as one means — by centralizing, one means a large share of the profits, I think it is probably a more useful framing to look at it instead in terms of absolutes, and in particular, the absolute surplus generated by the users.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":133,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"[MUSIC PLAYING]","formats":[]}]},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"EZRA KLEIN: What have you come to believe about the relationship between progress and war?","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":true,"index":134,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"PATRICK COLLISON: I am somewhat skeptical that war is as conducive to breakthroughs as we might intuitively conclude, or as is sometimes claimed. Youre probably familiar with Alexander Fields work on the 30s here. And his basic claim is, the productivity gains we often attribute to the Second World War in the U.S. — like, those foundations actually were laid in the 30s, and then the first half of the 40s were a period of decreasing productivity as we massively, inefficiently reallocated our economic resources for the purposes of winning the war, which was probably a good thing to do, but inefficient in narrow economic terms.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":135,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And he has a new book coming out, I think, next month, that sort of extends this argument into the 50s.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":136,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And as one takes stock of the scientific breakthroughs — and so Stripe Press recently republished Vannevar Bushs memoir, where he takes stock of this.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":137,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And obviously, you have, say, the Manhattan Project, and thats a big deal, certainly. But it doesnt feel to me that had the Manhattan Project not occurred, that peaceful development of nuclear technology would have been massively stymied. Maybe it would have taken another 10 years, but it was already happening to some meaningful extent.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":138,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And then, as you take stock of all the other breakthroughs that took place in the U.S. during the Second World War, there were some meaningful stuff like blood plasma and blood transfusions. There was some significant breakthroughs there. Some of the first antimalarial medications, radar, the proximity fuse, which Im not sure is all that useful outside of military applications.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":139,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"But by the time you get down to invention 6 on the list, I dont know that as you compare that list to, again, some counterfactual of what would otherwise have ensued, that it looks radically better as you take stock of the Cold War and the enormous fraction of our economic resources and human capital that were devoted towards us, that the gains necessarily look that impressive. And so again, its super hard to judge. You dont have proper controls and so on. But Im skeptical.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":140,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"EZRA KLEIN: Let me take the other side. So theres a question of, during war, how much did we invent during World War II. And thats a question of how much the threat of war or the competition with an adversary ends up charging up innovation and convinces us to put resources, both in terms of people and in terms of money, and maybe in terms of institutions, into projects we wouldnt otherwise have done.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":true,"index":141,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"I think theres an argument, at least, that we went to the moon because of the Soviet Union. It would not have done that for some time. Probably would have eventually done it, but also, who knows?","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":142,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"As Derek Thompson, who Im working on a lot of these ideas with, likes to point out, the Apollo Project was unpopular. It was not something that commanded wide popular support.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":143,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"Even now, if you look at the CHIPS Act that passed, it passed, with all that spending on semiconductor research and other kinds of next-generation technologies, under the framework of, lets compete more effectively with China. If you look at all the things Darpa has done or been part of, the fact that “defense” is the first word in the Darpa acronym, I think, is meaningful.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":144,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"Theres something about what threat persuades societies to do, and persuades them to do technologically or what risks it allows otherwise-more-cautious governments to take, or what failures they could justify that allows them to have big successes. Something there doesnt seem to small to me.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":145,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And maybe its my political side, where I so often see scientific funding justified in Congress in terms of countries were competing with or are adversaries with. And I see what the defense industry can do that other institutions cannot, because they dont get a lot of political blowback. But I dont know.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":146,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"I worry a little bit about how much we seem to need the threat of another to accelerate things. And in a small way, maybe, we see what the pandemic — where we were willing to move much, much quicker on things like mRNA technology than I think we would have outside of it.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":147,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"PATRICK COLLISON: Yeah. So I think its certainly true that the crisis can cause the discontinuous shifts that have large effects, which in your example, say, are probably super beneficial. I dont know. If you take Darpa as an example, it started as Arpa, as a more open-ended research institution and set of programs, and then with the Vietnam War, had the D pretended to it.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":true,"index":148,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And we decided, in the face of threat, to make it more applied, to take more seriously its translational and kind of, quote unquote, “competition-oriented mandate.” And I think that was bad for Darpa. And the internet, which arose under Arpa — its hard to think of innovations of similar magnitudes that then occurred in then-Darpas subsequent, say, two decades.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":149,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"If you take, say, U.S. science in general, the war — the Second World War — to some extent, the first, but much more so the second — precipitated an enormous centralization of U.S. science in its aftermath. Because we really marshaled together all of the — or a significant fraction of the scientific capacity of the U.S. in service of the war effort.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":150,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"For, example the 50 percent overhead, the fraction of government grants that goes to universities — that was chosen in the early days of the coordination of the war effort, and has now become a kind of a pillar of academic and research funding in the U.S. And in the aftermath of the war, we sort have this question of OK, weve kind of pulled everything together. Now, what do we do?","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":151,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And that became, in various ways, the N.I.H. and the N.S.F. and so on. I mean, the N.I.H. predated it, but the growth of the N.I.H. really occurred after the war. And the federal government, shortly thereafter, for the first time, became the majority funder of US science. And all that centralization — and I mean, you pointed out the benefits of variety and of experimentation and of heterogeneity, and having some degree of institutional and structural diversity and so on, I totally agree with all of that.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":152,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And I think all of that was very meaningfully curtailed by, again, the aftershocks of some of the threats that we faced during the war. And if you think about the things that were maybe happiest about having happened — the founding of the major new U.S. research universities in the latter parts of the 19th century or the revolution in health care and kind of medical practice that first happened at Johns Hopkins, and then kind of codified in the Flexner Report, or the great industrial research labs of Bell and Park and so on — or excuse me — Xerox — they didnt obviously come from a place of fear or a threat.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":153,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"They came from a place of hope and optimism and opportunity. And maybe there are some inventions that youre more likely to get to from some of these external pressures. But yeah, if you gave me a dial, and I can kind of turn up or down the threat or fear index of society, its not super obvious to me that one would want to turn it up if what one cared about was the aggregate rate of progress.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":154,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"EZRA KLEIN: Thats a good bridge, I think, to the question of institutions. And I take one of the main concerns of yours, of progress studies, as being around institutional slowdown. You have this idea that we dont meta-maintain institutions very well.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":true,"index":155,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"They start in one place, and then over time, they crust over, and we dont really know what to do with that. Give me a little bit of your thinking there.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":156,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"PATRICK COLLISON: I think institutions, the cultures they instill and act as kind of coordination points and training sites for — those of enormous consequence — I think much of the success of the U.S. and of various other Western countries has, in substantial part, been attributable to successful institutions. Most people would accept, I think, that there is, to some extent, consistent trends that tend to happen with institutions through time.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":157,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"Just maybe most basically, the problem that gives rise to an institution in the first place is probably a pretty real and significant problem. No one would have taken the time to found the institution if it wasnt. And there can be some degree of drift there, where we dont necessarily decommission the institution once the problem has subsided or abated.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":158,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And then, you tend to attract a certain kind of person in the early days of an institution — people who are slightly less status and reputation and procedure-oriented, because a new institution almost never has that. And then, through time, the sort of collective or the mission-oriented incentives of the institution can kind of drift somewhat from the individual incentives that particular people are subject to.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":159,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"I think all this stuff exists. And the thing that I observe, or that I just find myself thinking about is, weve had eras of institution formation in the U.S. It has not been kind of a constant rate through time. And the New Deal maybe, and say, the 30 years afterwards, and the Great Society — we bookend it with those start and endpoints.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":160,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"That was a period of tremendously active institution construction and formation in the U.S., Darpa being — or Arpa originally being a good example, and indeed, NASA. And I guess I find myself wondering, one, if we didnt have any of these institutions — and Im not saying we should get rid of them. But if we didnt have them, what institutions would we found today, first, and how high in the list would NASA be, for example?","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":161,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And then, secondly, in as much as we accept that some of these institutional dynamics exist, like the fact that sclerosis as an emergent property arises, what do we do about that? And lots of people have told us its pretty — doesnt need a lot of teasing apart to see it as one compares NASA and SpaceX and the respective budgets, and the respective achievements, and so forth, I think its hard to not at least wonder about their respective efficiencies.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":true,"index":162,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And say, if society could only have SpaceX or NASA, which one would we choose, and what should we conclude from that, and to what extent do those phenomena generalize elsewhere? I dont have answers to these questions. But I find that in the political discourse — not that anybody is celebrating that, but in the discourse, its very easy to get, I think, very wrapped up in questions of optimal funding levels, and should this number be 10 percent or 50 percent or higher or whatever, whereas to me, a lot of our satisfaction with the outcomes seems to hinge on deeper questions about the nature of the institution.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":163,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"I dont know that the problem or benefit, or anything good or bad about NASA is attributable to the budget, per se. It seems more, kind of, resonant in some of these deeper cultural questions. And then, in the recent pandemic, or in the — I dont know. I was going to say, ongoing pandemic. But I guess as of two days ago, with the Presidents verdict, it is now over.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":164,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"EZRA KLEIN: Its over. Congratulations, everybody.","formats":[]}]},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"PATRICK COLLISON: Exactly. But anyway, I think that was maybe a vivid demonstration of many of these dynamics, where I dont know this any of the story about the institutional response to the pandemic should be primarily one of funding. I think its much more about the dispositions and the attitudes and the cultural biases of entities like the N.I.H. and the F.D.A. and the C.D.C.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":165,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"EZRA KLEIN: I find the NASA SpaceX example an interesting and provocative one. Because on the one hand, I think what youre saying is completely true. And where a lot of the NASA programs and projects have gone in recent decades, is just — its sad. Its just a sad story.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":166,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And on the other hand, the idea that you — the thought experiment of choosing between NASA and SpaceX — the thing that it immediately asks is, well, you cant. Because without NASA, there is no SpaceX. And one way the private sector handles a lot of these questions — I mean, Im always struck by how much of the way biotech research works is that big pharmaceutical companies acquire small biotech firms that have made a breakthrough or have come up with a very promising candidate. This is kind of an accepted thing that the big companies — they do a fair amount of research, but a major, major innovation transmission there is small groups do more, quicker, and theyre just going to buy them. And the NASA SpaceX example has a little bit of that dynamic to it, although with a different mechanism of financing. And I dont know. I wonder if there arent deeper lessons there.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":167,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"PATRICK COLLISON: Yeah, I dont mean here in the NASA example — like, I dont think reducing it to a simple binary of this-or-that is correct. Its more, what should we make of the differences in these two organizations? And given those observations or beliefs, what do we then think an efficient outcome might look like?","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":168,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And do we think that where we are today — this prevailing status quo — is optimal? Or are there other things we can do better? And maybe an important thing to say within all of this is, to the extent that these are all kind of inevitably determined outcomes, maybe it doesnt really matter if we think things would be better or worse.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":true,"index":169,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"Were going to end up in the same place, regardless. But I think for all of these, its super contingent. And various aspects of both funding decisions and, kind of, the precepts and methodologies of the N.I.H., how we design I.P. law, how we regulate and require and run clinical trials — there are tons of individual contingent decisions that we kind of have collectively made that give rise to the biotech and to the pharma ecosystem.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":170,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And certainly, in the case of space, you know, like, it doesnt have to be this way other. Universes, no pun intended, are possible. I think perhaps the thing that people underappreciated with science in the U.S. is, it has been very different in the not-too-distant past.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":171,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"Peer review is a relatively recent invention. Modern journals are a relatively recent invention. As I mentioned, the federal government being the primary funder of basic research is a relatively recent invention.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":172,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And molecular biology was, in significant part, a thesis by Warren Weaver at the Rockefeller Foundation. Theres a thing here, and we should aggressively pursue it. But importantly, it was not — it required an institution, an organization, that was not part of the standard apparatus, for want of a better term.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":173,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And the Broad Institute, over the last 25 years, has been enormously successful in the field of genomics and functional genomics and CRISPR, et cetera. And the Broad Institute is itself a kind of structural innovation, breaking somewhat from the more traditional prevailing university model. And so I think the fact that so many of our successes are associated with some degree of structural and institutional change should be somewhat thought-provoking for us.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":174,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"EZRA KLEIN: Youve been trying to work in the space of institution-building here, too. I want to talk about Fast Grants and about Arc a little bit. So lets begin with Fast Grants. What is it, and what has it taught you?","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":175,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"PATRICK COLLISON: Well, its mostly “what was it.” In the early days of the pandemic — well, I should preface all of this by saying — well, Ill reaffirm my preface that I dont know, to every question. But more importantly here, I will say, my now-wife is herself a scientist. Weve known each other since we were teenagers. We spend a lot of time talking about science in various forms.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":true,"index":176,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"EZRA KLEIN: You met — am I allowed to say this? You met at a science competition.","formats":[]}]},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"PATRICK COLLISON: That is true. We met at a science competition, 100 teenagers, and —","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":177,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"EZRA KLEIN: And she beat you.","formats":[]}]},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"PATRICK COLLISON: And yes. I was the runner-up, and she was the winner. I had created a programming language and a new dialect of lisp, and she had created a new treatment for urinary tract infections. And so I really dont envy the judges for having to figure out what framework one should use to make all these comparisons and lots of other people.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":178,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"EZRA KLEIN: You sound a little bitter, man.","formats":[]}]},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"PATRICK COLLISON: [CHUCKLES] I was gonna say, but no, we can all agree this the correct outcomes ensued. Anyway, so we were living together in March of 2020, holed up. And a number of her friends and colleagues were unsurprisingly with, I guess, a large fraction of all biology scientists, were trying to urgently repurpose their work to figure out, well, could they do something that would be somehow benefit to accelerating the end of the pandemic?","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":179,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And by early April, so a couple of weeks into lockdown, when it was becoming apparent and striking to us, which was it is difficult for these people to get funding for their work. And that might sound a bit, kind of, surprising, because you think, well, dont they have some degree of money already? And couldnt they just go and just spend that?","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":180,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"But there are, obviously, significant rules around and restrictions around that which one can do with ones grant money. This is money provided by the government for a purpose. And so its not like you can go and readily spend it on something totally unrelated.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":181,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And the money is administered by the university, and so you have to go through their proper procurement processes. Point is, lots of restrictions on scientists pecuniary ability to suddenly repurpose the research agendas. And we kind of thought, well — we assume maybe in the early weeks, that presumably various bodies — I dont know who — some kind of amorphous other, some combination of C.D.C., F.D.A., N.I.H., philanthropies — whatever.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":182,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"Somebody will come along and just give these scientists the obvious money that society clearly should, so they can go, and they can pursue these programs. Didnt seem to be happening. I mean, to be fair, I dont want to give us too much credit.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":true,"index":183,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"Various people were doing things right off the bat in various different places, but we just personally knew of lots of specific examples of really good scientists who were unable to make progress of their work to the extent that they would like. So we tried to set up what we thought would be a pretty small initiative, and called Fast Grants.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":184,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"The basic idea would be, you send us some kind of proposal. And initially, within 48 hours, you would get a funding decision and either receive money or not. We started out with a pretty small amount of money.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":185,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"The initial donors — we were among them, but there were a number — contributed, best I recall, about $10 million. Launched the website early April 2020. Quickly inundated with, I think, four and a half thousand applications, which, given our promised 48-hour turnaround, was somewhat challenging.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":186,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"I should say this was myself. This was Silvana, my wife, and this was Tyler Cohen. So we had an immediate question as to, how do we actually run a philanthropic endeavor? And how do we stand it up in very short order? And he, through Mercatus and through Emergent Ventures, had some experience of very efficient and somewhat-scaled grant-giving.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":187,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And so the three of us worked together to put it together over the course of a week or so. We proceeded over the course of, roughly speaking, the next year, slightly more, to make about 200 grants, eventually dispersing almost — or slightly over, actually — $50 million in total, to universities around the world, though primarily in the U.S.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":188,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And you ask, kind of, what did we learn? A big surprise was how slowly other parts of the establishment mobilized. And various of the projects we funded or the labs we funded and so on — theyve gone on to now do — none of them were directly implicated in the vaccine research project that ended up yielding so much fruit. So again, I dont want to give Fast Grants too much credit. Eventually, the thing that really mattered, we had nothing to do with.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":189,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"But versus the projects, things like Saliva Direct, which was in the summer an early discovery that saliva tests work basically as well as the nasopharyngeal swabs we were all being subject to, or various discoveries around possible therapeutics, some of which are — still continue to go through clinical trials, and may still turn out to matter to a significant extent. And that 500 people are still dying in the U.S. per day from Covid, and — despite the existence of the vaccines and so on.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":true,"index":190,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"So anyway, various discoveries ensued that I think will prove to be important. And the second thing we learned, which is not really related to Covid or the pandemic, but has certainly been significant for us, is — it just got us thinking more deeply and broadly about the questions of, how do scientists choose what to do? And what are the constraints theyre subject to as a practical and applied matter?","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":191,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And this gets back to all this discussion about both culture and institutions. And towards the end of Fast grants, we ran a survey of the grant recipients. And these are essentially all people who dont normally — certainly dont normally work on Covid. Covid didnt exist.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":192,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"But they dont even normally work on viruses, for the most part. These are basically kind of broadly drawn as a cross section across biology. And we just asked them, as a general matter in your regular research, if you could spend your grant money however you want, how much would you change your research agenda?","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":193,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"So not an increase in the funding level, which tends to be what we discuss in as much as were discussing science policy across society. But much more specifically and narrowly, if you had complete autonomy in how you spend whatever grant money youre getting, how much of your research agenda would change? And our intuition was that maybe a third of people would like to be doing something meaningfully different to what they actually are.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":194,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"But of these scientists, and these are really good scientists, four out of five told us that they would change their research agendas, quote, “a lot.” We gave them three options. Not much, or not at all, a little, and then a lot. Four out of five chose the maximum option on our survey. So I just find this incredibly thought-provoking.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":195,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"Basically, we seem to be in a situation where most of our top scientists arent doing what they think would be best for them to do. And we could say, no, our various committees and governing bodies and decision-making apparatus and so on, they know better. And Im not saying it would be completely unreasonable for one to maintain that. But that would seem to be a very central question about the construction of our scientific apparatus. And I think that should give us some pause.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":196,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"EZRA KLEIN: There are a couple things there. One is that it is a consistent observation I have learning about new areas that there is a way were taught the thing works, or people think the thing works, and theres this huge middle layer. Right? So in politics, which I know very well, and legislation, you have the “Schoolhouse Rock” version of how a bill becomes a law. And then its, like, a filibuster is how a bill becomes a law or does not become a law.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":true,"index":197,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"We were talking about drug innovation earlier. I think the folk way people think it works is we make a discovery about a drug, and then, like, we make a drug out of it after some tests. But you talk to people who work on pharmaceuticals and just clinical trials.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":198,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And in science — I think if you had asked me as a high schooler, had some science classes, Id have told you something about the scientific method. And then you talk to a scientist, and its grants. Like, grants are how science works. Grants are the middle layer between — you are a scientist, and you can do some science. And grants are how the N.S.F. and the N.I.H. work. Theyre how a lot of the universities work. Theres fund-raising.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":199,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"I mean, there are different ways that it happens. To make the question of “Are we doing science well?” a little bit more precise, I think one version of that question is, “Are we doing grants well?” And I think that question is more tractable. People dont feel as defensive about it.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":200,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"But Ive talked to a lot of scientists in the course of my work. Ive covered health care for my entire career. And I dont know any who think were doing grants well. I dont know any who will not complain to you for hours.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":201,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And they may be wrong. And I do want to note — because they also just have somewhat different incentives. I mean, I was noting earlier, and I think its very real. The government, particularly when it gives out grants, needs to worry about the reputational cost of the grant. If the grant goes wrong, if not enough of the grants pay out into useful research. If Rand Paul can stand up in Senate and make what you did sounds silly, these things really end up mattering. And so you get a process that is optimizing for a lot of different things.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":202,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"But the question of whether or not we do grants well ends up being really, really, really important in every country that does major capital science that I know of, and is just not the main question for a bunch of different reasons we ask.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":203,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"PATRICK COLLISON: Yeah. Another question we asked in our survey was how much time they spend on the grants. I think to some extent, this is perhaps — at least, of those whove spent some amount of time interacting with scientists, kind of more broadly known than perhaps the finding with respect to how they do — or the degree to which they can choose what they work on. But we found that — or they reported to us that they spend on the order of 40 percent of their time on grant administration.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":true,"index":204,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And even if one were to maintain that the decision-making apparatus around what scientists do is somehow efficient, I think it is a very tenuous position to also try to argue that 40 percent of the best scientists time is optimally allocated towards grant applications, authorship and administration. And were not talking about an inconsequential 40 percent here.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":205,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"I mean, this is 40 percent of the time of this super-elite 10,000, 100,000, whatever it is, some relatively finite number of people. And weve chosen to take and to redeploy almost half of their time in service of technocratic, bureaucratic undertaking. And getting back again to this point about people perhaps falsely assuming that things have been more inter-temporally consistent than they have, that percentage has increased very substantially over the last couple of decades as the overall edifice of science has grown, and as the kind of acceptance rates and the various thresholds for various grants has become more exacting.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":206,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"EZRA KLEIN: How we allocate peoples time is really important. But also, just how we allocate talent is really important. And it brings me to something you said that I wanted to ask you about. This was in response to a question about whether big tech companies are hogging all the talent in society.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":207,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And you said, quote, “I dont think that the ambitious upstarts who go into high speed rail in America, anyway, are going to have a great time or have much success in convincing their friends to follow them. And I suspect that for various reasons, too many domains look somewhat like high speed rail.” And so you go on to say that theres a view that the internet is a frontier of last resort, and that you dont think thats totally wrong.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":208,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"So tell me about that. Tell me about the idea of the internet as a frontier of last resort. But behind that, this idea that other frontiers where talented people might want to go and make their mark on society have closed.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":209,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"PATRICK COLLISON: Youre familiar with and youve probably written about the Stephen Teles idea of kludgeocracy. And I kind of like the term “kludgeocracy,” because rather than making some of the inhibitions that people might encounter in pursuing something like high speed rail, rather than casting those as being deliberate, the valence is more that its this kind of emergent, inadvertent and kind of complicated phenomena that nobody perhaps particularly wants or chose.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":210,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And I think the case of Californias high speed rail is quite striking, where — youve written about this and kind of similar projects and the New York subway expansion and so on. And congestion pricing and so on. But its striking where its not actually obviously a question of first order political will.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":true,"index":211,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"Like, were willing to fund the high speed rail in California. Were clearly willing to invest in building the subway expansion in New York. But somehow, somewhere between that first order decision and desire and our actual ability to kind of instantiate it, something really goes wrong.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":212,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And you contrast that with stories of — in the case of, say, California, Henry Kaiser and these various other early part of the 20th century operators in the physical realm. And for a variety of reasons, but mostly prosaic state and county-level complications and things that would extend the time horizon of ones project, it has simply become meaningfully less-appealing for those people to undertake these initiatives. I mean, Foster City, not too far from where we are now, thats named after the eponymous Mr. Foster.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":213,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"He was a developer. He decided, well, with reclaimed wetlands, Im going to build a city. California is growing quickly. The Bay Area is a — kind of propitious and will be a long-term successful area. And I think this place simply needs more housing.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":214,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And he, with that kind of founder energy, was able to give birth and rise to the city that now bears his name. I havent met anybody pitching me on a similar city on the shores of the Bay in the last couple of years. But I would imagine that were one to adopt that ambition today and to propose that maybe the San Jose Marsh wetlands should themselves be an expansion of San Jose, I dont think one would get very far.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":215,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And in fact, even for much more sort of limited things, like additional runways or runway expansions at S.F.O., even they have now been stymied for decades at this point. That ability to translate that into something enunciated has dissipated and deteriorated. And then I think the kind of individual version is, and if I want to be that heroic solar farm entrepreneur or railway magnate, that my practical ability to do so has been meaningfully curtailed.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":216,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"EZRA KLEIN: Yeah. I mean, thats what Im getting at here a little bit, which is talent really matters for a society. Where the most talented people go really matters for society. And a lot of those people want to go somewhere where they can have a really big effect.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":217,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"I think theres been a huge rush to digital land because you can build on digital land. You can build quickly. I mean, its interesting to some of the dynamics were talking about, the temporal dynamics were talking about, that you see this dynamic even within the tech world.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":true,"index":218,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"There was a while where it was really exciting to go join Facebook, go join Google, go join one of the big companies. Because you could do so much. And thats still, to some degree, true. But they got really big.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":219,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And so crypto got — whatever you think of crypto, one thing that is exciting about it to people is the idea that its open land. That you can go in there and have a really big effect on it. Build something new just with a couple of friends that might change the whole direction of the field.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":220,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And on some level, its always going to be harder for, say, putting high speed rail through the middle of California. Right? I mean, just building things in the world is just going to be tougher.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":221,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"But on the other hand, if you make building things in the world too hard, if you make grants too difficult — if you — I know a lot of doctors who their advice to young people is dont become a doctor. And it always breaks my heart a little bit. We need really great people to be doctors.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":222,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And their point is not, dont go heal sick people. Their point is, being a doctor is too hard now. The amount of time you spend dealing with insurance agencies and malpractice insurance and boards, and this and that, its just too much administration.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":223,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"When industries become very complicated to operate in, you want to select for people who are good at operating complicated industries, which may be different than the people who are good at moving really fast and changing things dramatically. But two, you kind of subtly bias where different kinds of people in your society go. I think in China, if you want to change a lot, you still probably go into infrastructure construction, among other things. Right?","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":224,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"The idea that you might be a genius rail mind, in China, thats great. Theres probably a lot of rail you can make. Thats not true here. And the point is not to make too much of the rail example, but to make a lot of the idea that talent flows towards where it can have an effect and people can live the kinds of heroic lives they want to lead. And if we have subtly pushed a lot of people into maybe not the right — not the socially optimal directions, that over time will have a pretty big effect on a society.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":true,"index":225,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"PATRICK COLLISON: I think a constant is that some number of ambitious young people will want to do something, as you say, heroic. And yeah, I think maybe two things have changed. For one, for whatever reason, our predisposition to putting those people in positions of authority has diminished. And then secondly, even if placed, their ability to actually execute, again for various reasons, has been attenuated.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":226,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"Ive been reading about the university founders and presidents and those associated with some of the great US research institutions. And one thing that is striking is how many of them were so young when placed in those positions of authority. You know, Daniel Coit Gilman at Johns Hopkins, or William Rainey Harper at the University of Chicago. I think he was 32 when he was appointed president of the University of Chicago. Even in the recent past.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":227,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"So my dad was in the first year of the University of Limerick in Ireland. Or at the time, it was called N.I.H.E. It kind of acquired university status later in its life. And the Irish guy who founded it and was really the dynamo behind it, I think he was 29 when he was put in charge of that project.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":228,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And I think it was in 1970 or 71 that he was charged with this mission. But as recently as 1970 in Ireland, we were willing to put a 29-year-old — I mean, thats a person meaningfully younger than me in charge of the project of overseeing the creation of a major new research institution. And I dont know that I have compelling or confident observations to offer in terms of the etiology underlying these changes. But I think the changes themselves are important, or at least we should assume theyre important if we come from a place of humility, where this is what has worked in the past. Enabling these ambitious young people who are willing to contemplate spending multiple decades in pursuit of some ambitious and idiosyncratic vision.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":229,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And maybe were more enlightened now. Maybe we figured out how to get all the same innovation and all the same breakthroughs without unleashing that force. But I guess my starting point, at least, would be, well, we should — before getting super confident in that or before really being deliberate about it, I think we should give some kind of credit and credence to the prescription and the methodology thats worked heretofore.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":230,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"EZRA KLEIN: And before books, let me end on this. Weve talked a lot about scientific slowdown, about technological slowdown. But lets say in the next 15-year time frame, what are the three technological or scientific possibilities youre most excited by? If in 20 — I guess itd be 2037, were having a conversation about how dumb this conversation was because it was right on the cusp of so much incredible stuff happening, what do you think is likely to be on that list?","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":231,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"PATRICK COLLISON: I dont know that Ive super non-consensus answers. I think that there are fundamental a priori reasons to believe that the rate of progress in biology could increase substantially over the years, and to your question, kind of decades to come. So if in 2037 we are enormously impressed and struck by the discontinuity there, that would not shock me.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":true,"index":232,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"Clearly, over the past couple of years, theres been acceleration in progress in A.I. And kind of far for me to try to point estimate for kind of where that is in 2037. But I would be surprised if that is not somewhere on that list.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":233,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And then I think theres something about education in the broadest sense that feels to me like a very significant, and hopefully very positive change happening in the world right now. Maybe best embodied by YouTube. But also by Twitter and by blogs and Substacks and even Zoom and kind of the growing ease of being in some kind of cultural proximity to people one aspires to emulating, or following in the footsteps of, or otherwise kind of being more like.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":234,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And to the extent that one believes my story about the significance of sociology, and culture, and mentorship, and the kind of delicate transmission of tacit knowledge, it has until very recently only been possible for that to happen to a meaningful extent through physical co-location. And the fact that weve now thrown open those doors to such an extent feels to me like a really compelling and plausibly transformative change. And if it were the case in 2037 that we have multiplied by 20 the number of people who can — who have the initial mental models and understanding to become successful entrepreneurs, or successful scientists, or successful writers, or successful in whatever one might choose ones domain to be, again, I think that would not be shocking. And I think its a pretty hopeful fact about the world.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":235,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"EZRA KLEIN: And then always our final question. What are the three books youd recommend to the audience?","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":236,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"PATRICK COLLISON: Well, Im right now reading “Revolution and Empire,” which is a book about Edmund Burke. And it is just fabulous. I very highly recommend it.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":237,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"Edmund Burke, Irelands foremost political philosopher. And Im embarrassed to say that I have known less about him than I feel like I ought to have. So I recommend that very highly.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":238,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And the autobiography by Warren Weaver, who I mentioned, at Rockefeller. I cant remember if its called “Scene of Change” or “Scene of the Action.” But its Warren Weavers autobiography.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":true,"index":239,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"Thats not a great book in the sense that you dont read it — you dont find it to be a vivid, compelling page-turner. And your mind is not blown on every page. But I find myself thinking back to it quite a lot and having various parts of it sort of ricochet to my mind.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":240,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And then it all depends on what people are interested in and all the rest. And you should read the things you like. But I have on my desk at home right now “A Widening Sphere,” which is a history of M.I.T. And I was re-reading it recently. And my —","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":241,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"EZRA KLEIN: Who doesnt re-read the histories of M.I.T.?","formats":[]}]},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"PATRICK COLLISON: [LAUGHS] Well, William Barton Rogers, the founder, was the son of an Irishman, and started M.I.T. substantially with his brother. And I find it very inspiring, I guess back to what we were saying earlier, how motivated he was and they were by a kind of broad-based desire for societal betterment. Like, M.I.T. didnt inadvertently end up being a significant contribution to American prosperity and ingenuity and welfare. He was really immersed in that milieu.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":242,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"He paid a lot of attention to some of the cultural dynamics we were describing in England, and the Darwins. And the early writing on M.I.T., if you go and just read the first two pages of the founding manifesto, it wasnt utopian in some kind of implausibly lofty sense. But it was somebody who knew they werent founding a run of the mill nth technical college.","formats":[]}]},{"__typename":"Dropzone","adsMobile":true,"adsDesktop":false,"index":243,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"And I feel like its easy to get cynical always. Its easy to assume that the things that really worked out worked out through happenstance, as opposed to optimism and ambition. But yeah, I find the history of MIT to be a kind of inspiring reminder that sometimes these implausible, lofty, ambitious, long-term initiatives can work out much better than one would hope.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":244,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"[MUSIC PLAYING]","formats":[]}]},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"EZRA KLEIN: Patrick Collison, thank you very much.","formats":[]}]},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"PATRICK COLLISON: Thanks for having me.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":false,"index":245,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"[MUSIC PLAYING]","formats":[]}]},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"EZRA KLEIN: “The Ezra Klein Show” is produced by Annie Galvin and Rogé Karma. Fact-checking by Michelle Harris, Mary Marge Locker and Kate Sinclair. Original music by Isaac Jones.","formats":[]}]},{"__typename":"Dropzone","adsMobile":false,"adsDesktop":true,"index":246,"bad":false},{"__typename":"ParagraphBlock","textAlign":"LEFT","content":[{"__typename":"TextInline","text":"Mixing by Sonia Herrero, Isaac Jones and Carole Sabouraud. Audience strategy by Shannon Busta. 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