926 lines
96 KiB
HTML
926 lines
96 KiB
HTML
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<!DOCTYPE html>
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<title>
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Researchers Pinpoint Reason Infants Die From SIDS | BioSpace
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</title>
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<p>
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<span style="font-size: 14.6667px; line-height: 17.60004px;"><span style="font-family: sans-serif;">We use cookies to give you a better BioSpace experience. By continuing to use our site, you are agreeing to the use of cookies as set in our <a href="https://www.biospace.com/privacy-policy/" target="_blank">Privacy Policy</a>.</span></span>
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<a href="javascript:void(0);" id="hs-eu-confirmation-button" role="button">Accept</a>
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<noscript><iframe src="//www.googletagmanager.com/ns.html?id=GTM-N4MVRTW" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript> <!-- End Google Tag Manager Body -->
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<div class="container js-container">
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<a accesskey="S" title="Access key: S" href="#main">Skip to main content</a>
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</p>
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<div data-block="header-top" class="position-static"></div>
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<div data-block="header-main" class="position-static">
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<header role="banner" class="banner">
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<li class="togglable-nav__item secondary-nav__item secondary-nav--jobseekers jobseekers jobseekers-nav">
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<li class="togglable-nav__item jobseekers__item jobseekers__item--sign-in">
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<a href="/logon/">Login</a><span class="text or">|</span>
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<a href="/"><img src="//www.biospace.com/assets/dist/images/logo.png;v=3d4a2d9c30152a980c1e355d5990da83" title="BioSpace" alt="BioSpace logo" /></a>
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<div id="div-gpt-ad-1488483310486-0" style="padding-top: 20px; padding-bottom: 15px;">
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<script>
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googletag.cmd.push(function() { googletag.display("div-gpt-ad-1488483310486-0"); });
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<nav aria-label="Main" id="primary-nav" class="primary-nav togglable-nav js-togglable-nav">
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<li class="primary-nav__item">
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<button class="primary-nav__dropdown-button" href="#" aria-haspopup="true" aria-expanded="false">News</button>
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<ul class="primary-nav__dropdown" aria-label="submenu">
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|
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<a href="https://www.biospace.com/news/research/">Clinical Research</a>
|
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<a href="https://www.biospace.com/news/money/">Finance</a>
|
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|
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<li>
|
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<a href="https://www.biospace.com/news/coronavirus-covid-19-news/">Covid-19</a>
|
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</li>
|
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<li>
|
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<a href="https://www.biospace.com/news/">See all news</a>
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<li class="primary-nav__item">
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<button class="primary-nav__dropdown-button" href="#" aria-haspopup="true" aria-expanded="false">Jobs</button>
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<a href="/searchjobs/">Search jobs</a>
|
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<li>
|
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<a href="/newalert/">Job alerts</a>
|
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</ul>
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<li class="primary-nav__item">
|
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<button class="primary-nav__dropdown-button" href="#" aria-haspopup="true" aria-expanded="false">Hotbeds</button>
|
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<ul class="primary-nav__dropdown" aria-label="submenu">
|
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|
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<a href="https://www.biospace.com/biotech-bay/">Biotech Bay</a>
|
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|
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<li>
|
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<a href="https://www.biospace.com/genetown/">Genetown</a>
|
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|
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<li>
|
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<a href="https://www.biospace.com/biotech-beach/">Biotech Beach</a>
|
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</li>
|
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<li>
|
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<a href="https://www.biospace.com/biomidwest/">BioMidwest</a>
|
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|
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</li>
|
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<li>
|
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<a href="https://www.biospace.com/pharm-country/">Pharm Country</a>
|
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</li>
|
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<li>
|
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|
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<a href="https://www.biospace.com/hotbeds/">See all regions</a>
|
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|
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</ul>
|
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</li>
|
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<li class="togglable-nav__item primary-nav__item">
|
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<button class="primary-nav__dropdown-button" href="#" aria-haspopup="true" aria-expanded="false">Career Resources</button>
|
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<ul class="primary-nav__dropdown" aria-label="submenu">
|
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<li>
|
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<a href="https://www.biospace.com/news/interviews/">Interviews</a>
|
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</li>
|
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<li>
|
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|
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<a href="https://www.biospace.com/news/job-search-strategy/">Job search strategy</a>
|
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|
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</li>
|
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<li>
|
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|
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<a href="https://www.biospace.com/news/resumes-and-cover-letters/">Resumes & cover letters</a>
|
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</li>
|
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<li>
|
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<a href="https://www.biospace.com/careerfairs/">Events</a>
|
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|
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</ul>
|
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<li class="togglable-nav__item primary-nav__item">
|
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<a class="primary-nav__link" href="https://www.biospace.com/staticpages/10286/newsletters/">Newsletters</a>
|
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|
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<li class="togglable-nav__item primary-nav__item">
|
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<a class="primary-nav__link" href="/employers/">Company Profiles</a>
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<li class="togglable-nav__item primary-nav__item primary-nav__item--recruiter">
|
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<a class="primary-nav__link" href="https://employer.biospace.com/">Advertise</a>
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<div class="sector-nav--smallscreen" data-set="sector-nav"></div>
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<nav aria-label="Sector" id="sector-nav" class="sector-nav togglable-nav">
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<div class="wrapper">
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<div class="sector-nav--desktop" data-set="sector-nav">
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<ul class="sector-nav__items togglable-nav__items cf js-append-around">
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<li class="sector-nav__item sector-nav__item--first togglable-nav__item">
|
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<a class="sector-nav__link" href="/biotech-bay/">Biotech Bay</a>
|
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</li>
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<li class="sector-nav__item togglable-nav__item">
|
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|
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<a class="sector-nav__link" href="/biotech-beach/">Biotech Beach</a>
|
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</li>
|
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<li class="sector-nav__item togglable-nav__item">
|
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|
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<a class="sector-nav__link" href="/biocapital/">BioCapital</a>
|
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</li>
|
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|
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<li class="sector-nav__item togglable-nav__item">
|
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<a class="sector-nav__link" href="/biomidwest/">BioMidwest</a>
|
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</li>
|
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<li class="sector-nav__item togglable-nav__item">
|
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<a class="sector-nav__link" href="/bio-nc/">Bio NC</a>
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<li class="sector-nav__item togglable-nav__item">
|
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<a class="sector-nav__link" href="/bioforest/">BioForest</a>
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Researchers Pinpoint Reason Infants Die From SIDS
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<span class="palm-block-level">Published: May 11, 2022</span> <span class="palm-block-level">By Rosemary Scott</span>
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<img alt="BabyFeet/Getty" src="https://admin.biospace.com/getasset/bae8d5ab-791d-40ac-b9ed-2e44427100dd/?&Test=Test" />
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Sudden infant death syndrome (SIDS) accounts for about 37% of sudden unexpected infant deaths a year in the U.S., and the cause of SIDS has remained largely unknown. On Saturday, researchers from The Children's Hospital Westmead in Sydney <strong><a href="https://www.sciencedirect.com/science/article/pii/S2352396422002225">released</a></strong> a study that confirmed not only how these infants die, but why. 
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SIDS refers to the unexplained deaths of infants under a year old, and it usually occurs while the child is sleeping. According to <em>Mayo Clinic</em>, many in the medical community <strong><a href="https://www.mayoclinic.org/diseases-conditions/sudden-infant-death-syndrome/symptoms-causes/syc-20352800#:~:text=SIDS%20is%20sometimes%20known%20as,breathing%20and%20arousal%20from%20sleep.">suspected</a></strong> this phenomenon could be caused by a defect in the part of the brain that controls arousal from sleep and breathing. The theory was that if the infant stopped breathing during sleep, the defect would keep the child from startling or waking up. 
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The Sydney researchers were able to confirm this theory by analyzing dried blood samples taken from newborns who died from SIDS and other unknown causes. Each SIDS sample was then compared with blood taken from healthy babies. They found the activity of the enzyme butyrylcholinesterase (BChE) was significantly lower in babies who died of SIDS compared to living infants and other non-SIDS infant deaths. BChE plays a major role in the brain’s arousal pathway, explaining why SIDS typically occurs during sleep. 
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Previously, parents were told SIDS could be prevented if they took proper precautions: laying babies on their backs, not letting them overheat and keeping all toys and blankets out of the crib were a few of the most important preventative steps.
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While safe sleep practices are still important for protecting infants, many children whose parents took every precaution still died from SIDS. These parents were left with immense guilt, wondering if they could have prevented their baby’s death.
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Dr. Carmel Harrington, the lead researcher for the study, was one of these parents. Her son unexpectedly and suddenly died as an infant 29 years ago. In an interview with the <em>Australian Broadcasting Corporation (ABC)</em>, Harrington <strong><a href="https://www.abc.net.au/news/2022-05-08/sydney-researchers-find-enzyme-marker-could-prevent-sids/101047156">explained</a></strong> what she was told about the cause of her child’s death. 
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"Nobody could tell me. They just said it's a tragedy. But it was a tragedy that didn't sit well with my scientific brain.” 
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Since then, she’s worked to find the cause of SIDS, both for herself and for the medical community as a whole. She went on to explain why this discovery is so important for parents whose babies suffered from SIDS. 
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"These families can now live with the knowledge that this was not their fault," she said.
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In the study, the researchers wrote, “This finding represents the possibility for the identification of infants at risk for SIDS infants prior to death and opens new avenues for future research into specific interventions.” 
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As the cause is now known, researchers can turn their attention to a solution. In the next few years, those in the medical community who have studied SIDS will likely work on a screening test to identify babies who are at risk for SIDS and hopefully prevent it altogether.
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